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Inflammatory Bowel Disease (Ibd)

Inflammatory bowel disease (IBD) describes two conditions - Crohn's disease and ulcerative colitis - where the gastrointestinal tract becomes inflamed and damaged over time. Common symptoms include abdominal pain, diarrhea, bloody stools, and weight loss. While the causes are unknown, genetics and an overactive immune system are thought to play a role. Diagnosis involves blood tests, endoscopy, and biopsies. Treatment ranges from medications to manage symptoms to surgery to remove inflamed sections of the bowels.
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0% found this document useful (0 votes)
325 views3 pages

Inflammatory Bowel Disease (Ibd)

Inflammatory bowel disease (IBD) describes two conditions - Crohn's disease and ulcerative colitis - where the gastrointestinal tract becomes inflamed and damaged over time. Common symptoms include abdominal pain, diarrhea, bloody stools, and weight loss. While the causes are unknown, genetics and an overactive immune system are thought to play a role. Diagnosis involves blood tests, endoscopy, and biopsies. Treatment ranges from medications to manage symptoms to surgery to remove inflamed sections of the bowels.
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INFLAMMATORY BOWEL DISEASE(IBD)

(CROHN'S DISEASE/ULCERATIVE COLITIS)

WHAT IS INFLAMMATORY BOWEL DISEASE?


Inflammatory Bowel Disease (IBD) is a term for two conditions (ulcerative colitis and
Crohn's disease), that is characterized by chronic inflammation of the gastrointestinal
tract and this prolonged inflammation causes damage to GI tract.
Crohn's disease causes inflammation of your digestive tract and presents as symptoms
of severe diarrhea, abdominal pain, fatigue, weight loss and malnutrition. Crohn's disease
can involve different parts of your gastrointestinal tract in different people.
Ulcerative colitis on the other hand is a long-term condition where distal parts of the
gastrointestinal tract such as the colon and rectum are inflamed and ulcerated with pus
production.

SIGNS AND SYMPTOMS:


The severity and incidence of symptoms varies among different people, however the
common symptoms experienced are,
● Bloody Stools
● Abdominal Pain
● Diarrhea
● Fever
● Rectal Pain
● Weight Loss
● Fatigue
● Malnutrition
● Feeling of full bowel even after defecation

Additional symptoms which are uncommon but may present are,


● Joint Pain and Swelling
● Nausea and Decreased appetite
● Skin problems
● Mouth sores
● Perianal Fistula
● Eye Inflammation
● Shortness of breath
● Decreased ability to exercise

CAUSES OF INFLAMMATORY BOWEL DISEASE:


According to researcher’s ulcerative colitis occurs due to an overactive immune system,
however, other factors that may contribute are genes, immune disorders and
environmental factors such as bacteria, virus and microorganisms.
The causes of Crohn’s disease are somewhat similar to ulcerative colitis, and the factors
that affect the severity of disease are smoking status, age, rectum involvement and
duration of time you have had the disease.

WHAT ARE RISK FACTORS OF IBD?


The common risk factors of Ulcerative colitis and Crohn’s disease are age, race, ethnicity,
family history, lifestyle, smoking, and appendectomy.

DIAGNOSIS:
For diagnosing Crohn’s disease or Ulcerative Colitis, no single diagnostic test is sufficient
and the tests commonly used to deduct diagnosis are,
● Blood Tests
● Stool Test
● Endoscopy
● Colonoscopy
● Imaging Techniques (CT Scan, Ultrasound, MRI)
● Biopsy or Tissue Sampling

MANAGEMENT OF IBD:

Medications:
The medication that your doctor will prescribe you depends upon the severity of your
symptoms and the commonly prescribed ones are Mesalamine, Sulfasalazine,
Balsalazine, Olsalazine and 5-aminosalicylate for mild symptoms. And if you have
moderate to severe symptoms, you may be prescribed Infliximab, Vedolizumab,
Ustekinumab, and Tofacitinib.

Surgery:
If less invasive treatments and lifestyle changes do not cure and lessen the symptoms of
inflammatory bowel disease, surgery becomes necessary and in 75% of people, it is the
ultimate necessary thing to do. Surgery involves removing the damaged portions of your
digestive tract and reconnecting the healthy portions.

REFERENCES:
https://www.healthline.com/health/crohns-disease
https://www.healthline.com/health/ulcerative-colitis
mayocl.in/3kjbmhX

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