Serial Comparison Algorithm Reference
Serial Comparison Algorithm Reference
Revision B
December 2015
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Philips Medizin Systeme
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PN 453564373101 Hewlett Packard Str. 2
Revision B 71034 Böblingen
Printed in USA German
Edition History
Revision A, June 2012
Revision B, December 2015
Copyright
Copyright © 2015
Koninklijke Philips Electronics
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Andover, MA 01810-1099 USA
(978)687-1501
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What is New? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
How the Serial Comparison Algorithm Analyzes Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Monitoring Infarct Evolution . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Overview of Serial Comparison Rules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Ventricular conduction delay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
Right Ventricular Infarct/Injury . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Requirements for Performing Serial Comparison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Serial Comparison Statement Display Options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
Comparing ECGs Using the Serial Comparison Algorithm. . . . . . . . . . . . . . . . . . . . . . . . 18
Undoing a Serial Comparison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
1
About the Philips Serial Comparison Algorithm
The following 2 statements apply only to an ECG that was serially compared on a
TraceMasterVue C.03.xx system (or older):
Serial comparison markings are displayed in every view in the ECGVue application
(unless you elect to hide statements, or serial comparison modifiers and/or symbols are
hidden at your site).
Serial comparison markings may also be present on the printed report, depending on the
settings at your site.
NOTE The support for serial comparison modifiers and/or symbols was discontinued in IntelliSpace ECG
A.01.
NOTE You can also perform a visual comparison between two ECGs by displaying them simultaneously on
the screen in Waveform view. This method does not involve the serial comparison algorithm. For
details, see the section on using the Waveform view in the client application Instructions for Use.
On a site-wide basis, the administrator can configure some display options for serial
comparison modifiers. See “Serial Comparison Statement Display Options” on page 18.
What is New?
In 2014 Philips introduced a new version of the DXL ECG analysis program(PH 110C) that
improves detection of acute myocardial infarction when ST confounders are present. The
following serial comparison algorithm modifications were made for compatibility with the
new Philips DXL algorithm.
When the serial comparison algorithm recognizes a significant change in rhythm, the
previous rhythm is called out in the summary.
1. Dr. J. Greenfield, Duke University; Dr. L. Crevasse and Dr. M. Ariet, University of Florida
For the rhythm categories, the algorithm uses a “statement only” approach, and does not
take measurements into account outside of heart rate. Similarly, in those few cases where
measurements are not available in the previous ECG, only statements are compared for the
diagnostic categories.
Although the comparison is only between two ECGs, the results of comparisons are
cumulative, so long as there are no significant measurement changes that would justify the
removal of a statement and statements are not deleted by an editing cardiologist. This allows
a diagnosis to be retained indefinitely.
The serial comparison algorithm compares interpretive statements and the waveform
measurements for each ECG to determine whether any change in statements is significant.
After performing the serial comparison between two ECGs, the comparison program adds
and/or deletes statements, as appropriate. The complete set of statements is saved with the
ECG.
NOTE You can undo the comparison at a later time, for example, if the comparison ECG was invalid, or a
more representative ECG was acquired that you want to compare to. For details, see “Undoing a
Serial Comparison” on page 18.
The comparison program is designed to compare abnormal conditions by category, which
correspond to the ECG diagnostic categories such as Basic Rhythm, Left Ventricular
Hypertrophy (LVH), Inferior Infarct , and so on. The program only looks for changes of
condition in those categories that correspond to the statements found in the interpretation
of the ECGs being compared.
The rhythm and morphology categories are analyzed as follows:
For rhythm categories, in addition to rhythm statement, heart rates are compared to
determine whether, for the same rhythm statement in the current and previous ECGs,
the heart rate has changed by 20 bpm or more.
NOTE This threshold can be configured by the user. See Configuring IntelliSpace ECG for more
information.
For the morphology categories, the program uses the concept of significant/insignificant
change. A significant change represents a change in a measurement variable that exceeds
the predefined limit. The change can be positive or negative, indicating a move toward a
higher or lower degree of severity within a category. For key threshold values used, see
Table 1.
Serial comparison is particularly helpful for tracking the evolution of myocardial infarction.
The program automatically includes the date of analysis in any infarct statement that has the
modifier “acute” or “recent” to indicate the date of the infarct. When serial comparison takes
place, if the date of the previous ECG is within 14 days of the current date, the program looks
for significant ST, T, or Q wave changes in the leads relevant to the infarct location. If the
changes are significant, the infarct is marked as Evolving. If changes continue on the next
ECG, the statement reads Evolution Continues.
in which the infarct is first identified as acute, and carries this date through successive ECGs.
The age of the infarct impacts how the data are compared.
1 First, there must be an infarct statement in the current ECG in a specific category of
interest. The previous ECG must also have an infarct statement in the same or related
category. That is, anterior MI (AMI), anterior lateral MI (ALI), lateral MI (LMI) or
inferior MI (IMI), posterior MI (PMI), lateral MI (LMI).
2 The evolution logic looks for significant measurement differences (SMD) in the category
of interest. The differences are generally an increase or decrease in the involved leads in
one of the following measurements:
– ST onset of +/-0.1 mV
– T amplitude of +/-0.2 mV
– Q duration of +/-20 ms
3 If the infarct evolution logic indicates there are SMDs and there is less than 15 days
between the current ECG and the date when the infarct was first identified as acute, and
the previous infarct is not evolving, the Evolving Infarct statement (MI-97) is generated.
If the previous infarct is evolving, the Evolution Continues (MI-98) statement is
generated.
If the previous infarct statement is evolving and there are no SMDs, the No Further
Evolution (MI-99) statement is generated.
4 Once the infarct age reaches 15 days, evolution logic is discontinued. If there is an
evolution statement in the previous ECG, the current infarct statement is used. The
exception is if an ST-onset elevation of 0.1 mV remains in the involved leads, then the
ST Elevation Persists (MI-93) statement is generated. After 60 days, this statement is
replaced by the current infarct statement.
5 If at any time there is no current infarct statement in the category or related category,
the infarct evolution statement is removed.
In an acute/evolving phase, it is likely that the ECG tracings of infarct location correspond to
a single occlusion in the coronary arteries. In a series of serial comparisons, the location of the
infarct may appear to change due to minor measurement variations that trigger different
statements due to exceeding different algorithm thresholds. The algorithm minimizes this
variability by grouping some infarct locations to represent the same occlusion. For example,
a statement of acute inferior infarct in an analysis can be followed by a statement of posterior
infarct in the next ECG. When this happens, the algorithm reports the inferior infarct (acute or
evolving) and adds the statement, Consider Posterior Wall Involvement (CPWI).
The algorithm has been tested extensively in clinical settings against cardiologist edits to the
interpretive statements. In general, it has been found that the number of editing changes
cardiologists need to make to the interpretive statements generated by the analysis algorithm
is greatly reduced when ECGs are compared versus when individual ECG analyses are
reviewed.2 This reduction occurs in part because the serial comparison algorithm benefits
from any edits made to the previous ECG and because SMDs need to be present for most
statements to be changed.
2. Gregg RE, Deluca DC, Chien CH, Helfenbein ED, Ariet M. Automated serial ECG comparison improves
computerized interpretation of 12-lead ECG. J Electrocardiol 2012; 45: 561-5.
Conduction Disturbance
Infarcts (continued)
Rhythm Comparison
The algorithm compares primary and secondary rhythm between the two ECGs.
Primary rhythm changes. Primary rhythm changes are always labeled as Significant
rhythm changes.
Primary rhythm:
“Sinus”, and related subcategories, including among others, “sinus bradycardia”,
“sinus tachycardia”, “sinus arrhythmia”. “Atrial”, and subcategories including “atrial
fibrillation”, “atrial flutter”, and so on. “Junctional” and “Ventricular” and related
subcategories.
These changes are labeled as follows:
Significant rate increase if the rhythms have the same condition and the current
rate is 20 or more beats per minute (bpm) greater than in the previous ECG.
Significant rate decrease if the rhythms have the same condition and the current
rate is 20 or more bpm smaller than in the previous ECG.
No change in rhythm.
When a change occurs between sinus rhythm (SR) and sinus arrhythmia (SA), the
statement No significant rhythm change is added, since these are both types of
sinus rhythm.
A change in rate (20 bpm) is not labeled significant rhythm change unless the basic
rhythm statements change between normal sinus rhythm and sinus bradycardia or
sinus tachycardia.
Secondary rhythm changes. Secondary rhythm changes are always labeled as
No significant changes.
Secondary rhythm is the second rhythm statement on the report and comprises
premature complexes; pauses; AV block, AV conduction; miscellaneous arrhythmias;
pre-excitation.
These changes are labeled as follows:
Rate increase when the rate is higher than in the previous ECG.
Rate decrease when the rate is lower than in the previous ECG.
No change in rhythm (= and Remains).
Contour/Morphology Comparison
The algorithm looks at each statement in the previous ECG and develops a list of categories
that are present, and then compares the two ECGs for each of the categories at a time,
See Table 1 on page 6 for the threshold values used for key categories.
When examining Infarct categories, if the statement modifier in the current or previous
ECG is Acute, the program determines whether there are significant Q, ST, or T
changes in the appropriate leads, and labels the changes as follows:
Evolving when the ECG date is within 14 days of the acute infarct date and relevant
measurement changes are significant.
Evolution Continues when the ECG date is within 14 days of the acute infarct date,
the previous ECG had the Evolving statement, and there continue to be significant
evolution changes.
No Further Evolution when the ECG date is within 14 days of the acute infarct
date, and there are no significant evolution changes.
ST Persists when the ECG date is more than 14 days from the acute infarct date,
and relevant measurement changes are significant.
The following table summarizes the SC05 serial comparison statement set.
Table 4 SC05 serial comparison statement set
Summary Statements
For each comparison performed, one of the following summary statements is added to the
ECG.
Significant Rhythm Changes Added when there is a change in the primary rhythm or
has a change of 20 bpm or more
Significant Contour Changes Added when Now Present, Now Absent, More
Prominent, Less Prominent modifiers are present
Significant Rhythm and Contour Added when a combination of the rhythm and contour
Changes statements are present.
No Significant Change Added when there is no significant change in
measurements.
Statement Criteria
VCD which are based primarily on QRS duration, whereas others are related to pronounced
QRS axis deviation. Because some of these conditions can exist together, the DXL program
includes combination statements such as “Incomplete RBBB and LAFB” or “Borderline
IVCD with LAD.” Even more complications arise because some of these conditions may hide
others; for example, the presence of right bundle-branch block (RBBB) makes the diagnosis of
any underlying borderline incomplete VCD (IVCD) impossible. We can apply the same idea
to the axis deviation area and say that left axis deviation is “masked” by left anterior fascicular
block (LAFB).
In the SC algorithm design, we split the compound statements into their components. In the
design, the conditions are laid out in a directed graph so that as one progresses along the graph
(as in borderline IVCD to incomplete right bundlebranch block to RBBB), the later conditions
cover up (mask) the previous ones. For conditions that can coexist, such as LAFB and RBBB,
there is no path to get from one to the other.
When the comparison algorithm starts the VCD category analysis, any compound statements
are split into their component conditions. Those components are scanned to find any masking
relationships between current and previous conditions. If any masking condition is noted, the
statements will be changed according to the rules described in Table 7. Finally, the program
will attempt to recombine the results into compound statements whenever the appropriate
statement exists.
Table 7 Summary of the criteria used in the category of VCD
Masking
Current masks previous Label masking (current) Label masking (current)
(previous to current in statement “now present” and statement “insignificant
downward direction) suppress masked (previous) measurement” and suppress
condition masked (previous) condition
Unmasking
Previous unmasks current Label unmasked (current) Label masking (previous)
(previous to current in statement “remains” and statement “remains” and
upward direction) label masking (previous) suppress unmasked (current)
statement “now absent” condition
ECG 16 minutes later indicates that there is an evolving inferior infarct and enough ST
elevation in V4R to trigger the RV involvement statement.
Figure 1 Panel A, The first ECG indicates the presence of inferoposterior infarct.
Panel B, The DXL interpretation indicates RV involvement in addition to
inferoposterior infarct.
Exclusion criteria ECGs that meet the conditions in this section cannot be serially
compared.
Current and/or previous ECGs with paced rhythm or paced
complexes are not compared.
Current and previous ECGs that are for a pediatric (age <
16) patient. (Serial change is generally not a major concern
in pediatric ECG analysis.)
System-defined criteria Serial comparison must be enabled on the system by your
for performing serial IntelliSpace ECG administrator.
comparison
Current and previous ECGs must have been analyzed with
a supported criteria version.
Supported versions are 08, 09, 0A, and 0B.
Current and previous ECGs must have interpretive
statements.
If the current or previous EGG’s measurement matrix is not
present, the serial comparison algorithm performs a
statement-based comparison.
If there is a mismatch in age or gender, or a significant
change is detected in height, a comparison is still
performed, but a statement is added to the current ECG
regarding the mismatch.
Uncoded statements, remarks, and custom statements are
not compared.
Current and previous ECG must have standard 12 or 12+
(e.g. 15-lead, 16-lead) electrode placement.
Current and previous ECG must not have any “No further
analysis...” coded statements.
Site-specific These settings are configured for your site by the IntelliSpace
(Administrator defined) ECG administrator using the System Configuration utility on
criteria for performing the server.
serial comparison
These requirements for serial comparison are in addition to
those described above.
NOTE The options below show the factory default setting. Check
with your administrator to determine whether changes were made.
Previous ECG is or is not confirmed, as configured at your
site.
Contact your IntelliSpace ECG administrator to determine
what the setting is.
The algorithm checks whether the previous ECG is more
than a few minutes older than the current ECG to be used in
comparison, based on the time interval configured by your
administrator.
If the time difference does not meet the requirements, the
algorithm checks the next previous ECG. By default, the
time difference is set to 30 minutes. You can decrease this
time interval, if desired, in 1 minute increments, to a
minimum of 1 minute.
Previous ECG must be from same institution, and
optionally, facility (or not) as configured at your site.
The location-related options depend on a variety of system
configuration factors. Talk with your administrator about
the exact location requirements for serial comparison at
your site.
When undoing a comparison, the system removes any statements that were added to the ECG
during serial comparison, as well as any edits that were made to the statements after the serial
comparison was performed. The ECG is returned to the state it was in immediately prior to
comparison. After saving the changes, you can perform a new serial comparison on the ECG,
if desired.
NOTE If an ECG has undergone multiple serial comparisons, any changes prior to the immediately previous
serial comparison are not modified.
Printed in USA
453564373101
Revision B
December 2015
*453564373101*
*B*