Received: 15 July 2019 Revised: 9 August 2019 Accepted: 14 August 2019

DOI: 10.1002/ptr.6494

REVIEW

Nutricosmetics: A brief overview

Irene Dini | Sonia Laneri

Department of Pharmacy, University of Naples

Federico II, Naples 80131, Italy The nutricosmetics are products and ingredients that act as nutritional supplements
to care skin, nails, and hair natural beauty. They work from the inside to promote
Correspondence
Irene Dini, Department of Pharmacy, beauty from within. Nutricosmetic is the latest trend in the beauty industry. This
University of Naples Federico II, Via Domenico
tendency rapidly gained many followers because it fits with the modern culture:
Montesano 49, Naples 80131, Italy.
Email: [email protected] Today, consumers are very careful with the food that they introduce into their
body, and there is also an increasing demand for natural products able to enhance
one's health and beauty without side effects and significant traction before use.
However, many nutricosmetic products are considered effective due to the histor-
ical use and word of mouth. Comprehensive analysis of the global nutricosmetics
market is conducted considering form, end‐user applications, and some product
components such as collagen, peptides, proteins, vitamins, carotenes, minerals,
and omega‐3 fatty acid are reported. Plant extract ingredients used in nutricosmetic
are also described.

K E Y W OR D S

hair care product, key market segments, nail care product, nutricosmetics, skin care product,
regulation

1 | N U T RI C O S M E T I C M A R K E T 2 | N U T R I C O S M ET I C SU P P LE M E N T S

The term “nutricosmetics” defines ingestible natural health pro- Nutritional (food) supplements are concentrated sources of mole-
ducts that enhance the function and appearance of human skin, cules with a nutritional or physiological effect (Piccardi & Manissier,
nails, and hair. They are agents that increase beauty internally with 2009) and contain nutrients (collagen, peptides, proteins, vitamins,
protective or responsive effects that offer beautification and/or carotenes, minerals, and omega‐3 fatty acids) derived from food
personal hygiene benefits. Nutricosmetics market will reach 7.9 bil- products and/or herbal and fruit extracts concentrated in a liquid, pill,
lion in 2025 registering a compounded average growth rate of capsule, powder, or tablet form. They are widely available in the mar-
5.0 % in the forecasted period (Global Industry Analysts, 2017). ket and are mostly sold as over‐the‐counter products.
Europe is the largest investor in the market, followed by
Asia‐Pacific and North America. Asia‐Pacific is the fastest growing
region in the market. This positive trend is due to consumers'
alertness regarding esthetic demand, skin aging, and wrinkle forma- 3 | N U T R I C O S M ET I C F O O D A N D
tion. Nutricosmetics are consumed orally by supplements or by food BEVERAGES
fortification in liquid and solid forms. Generally, antiaging and skin
care nutricosmetics are produced as pills, whereas the ones that Nutricosmetic food and beverages are functional foods in which
concern skin care and body health are proposed in liquid form. The some molecules with medical or beauty benefits have been added.
major target of nutricosmetics is the skin care products market. Snack bars, bakery products, and confectioneries are fortified foods
The stringent regulations are the major restraint in the global used by the beauty nutricosmetic industry to ameliorate skin, nails,
nutricosmetics market. and hair beauty appearance. Fortified beverages such as fortified

Phytotherapy Research. 2019;1–10. wileyonlinelibrary.com/journal/ptr © 2019 John Wiley & Sons, Ltd. 1
2 DINI AND LANERI

water, herbal tea, fortified coffee, and fruit and vegetable juices help cytokines to promote wound healing (Huang, Wang, Yang, Chou, &
the natural skin hydration. Fang, 2018).

5.2 | Peptides: Collagen peptides

4 | N U T RI CO S M E TI C S R E G U LA T I O N
Collagen is a structural protein of connective tissues (skin, cartilages,
Under the Dietary Supplement Health and Education Act (1994),
tendons, and bones). There are various collagen types, but the most
the Food and Drug Administration regulates the nutricosmetic
studied is Type II collagen (Figure 2).
market in the United States. In Europe, the framework of Regulation
It is produced in the connective tissue by fibroblasts and in numer-
1924/2006 guidelines of the European Food Safety Authority “guid-
ous epithelial cells (Matsuda et al., 2006). Collagen supplements are
ance on the scientific requirements for health claims related to
used to maintain skin, hair, nails, and body tissue healthy. Oral collagen
bone, joints, skin, and oral health” delimits health claims relating to
peptide supplementation significantly increases skin hydration and
“maintaining the normal structure of the skin, its hydration, elasticity,
the fragmentation of the dermal collagen network inducing collagen
or appearance.” Nutricosmetics are evaluated by member states on a
and glycosaminoglycan production (Asserin, Lati, Shioya, & Prawitt,
case‐by‐case basis. Foods for Specified Health Uses rules clearly state
2015). Moreover, collagen supplements, improving creatine formation,
what can and cannot be claimed for a product in Japan.
enhance the lean muscle gain, decrease recovery time, reconstruct
damaged joint structure, and advance cardiovascular performances
5 | K E Y M A R K E T SE G M E N T S OF (Asserin et al., 2015).
N U T RI CO S M ET I C S C O V E R ED BY T YP E
5.3 | Polysaccharides: Hyaluronic acid
The market is segmented based on the audience's behavior, treatment,
preference, and decision making. These variables depend on the Hyaluronic acid (HA) is a polysaccharide composed by D‐glucuronic
product to be marketed. Ingredient trend includes use of food ingredi- acid and N‐acetyl‐D‐glucosamine (Figure 3). It is a constituent of the
ents, novel ingredients, fair trade ingredients, and sourcing locally. The skin extracellular matrix and plays a key role in the dermis metabolism.
market by ingredient is segmented into lipid, peptides, polysaccha- With aging, the epidermal HA content decreases, and in senile skin,
rides, minerals, vitamins, secondary metabolites, and plant extracts. It when there is a low content of this product, the epidermis's ability
is supposed that the description of the ingredient and of their use to retain water decreases with the consequence of a loss in skin mois-
influences the individual buying decision. ture. HA supplementation enhances skin elasticity and skin hydration
and reduces skin roughness and wrinkle depths (King'Ori, 2011).
5.1 | Lipid: Omega‐3 fatty acids
5.4 | Minerals
Omega‐3 polyunsaturated fatty acids (docosahexaenoic acid,
eicosapentaenoic acid, α‐linolenic acid, and linoleic acid; Figure 1) 5.4.1 | Zinc
are used in skin‐related diseases to ameliorate the symptoms of
photoaging, cancer, dermatitis, wound healing, and melanogenesis. Zinc is a micronutrient involved in cell division, metabolic process,
They compete with the arachidonic acid to inhibit proinflammatory immune system functioning, glycemic control, antioxidant defense
eicosanoid production and regulate the synthesis and the activity of mechanism, coagulation, and wound healing. Dietary supplements

FIGURE 1 Omega‐3 fatty acids [Colour

figure can be viewed at wileyonlinelibrary.
com]
DINI AND LANERI 3

FIGURE 2 Type II collagen

FIGURE 3 Hyaluronic acid

contain several forms of zinc in percentage of elemental zinc vari-

able. Zinc plays an important role in morphogenesis, repair, and
maintenance of the skin, being an essential cofactor for several
metalloenzymes (MMPs), superoxide dismutase, metallothionein, and FIGURE 4 Vitamins
RNA polymerases (Gollner, Voss, Hehn, & Kammerer, 2017).

5.4.2 | Selenium 5.5.2 | Vitamin C

Vitamin C (Figure 4) is a hydro‐soluble vitamin with antioxidant prop-

Selenium is an antioxidant trace element. In nature, there are two sele-
erties. It is a cofactor in systemic biosynthesis, participates in meta-
nium forms: selenate and selenite (inorganic) and selenomethionine
bolic processes as a molecule transferring electrons, influences the
and selenocysteine (organic). Both forms are good dietary sources,
collagen biosynthesis, speeds up wound and bedsore healing, contrib-
but the human body absorbs 90% of the organic form and only 50%
utes in the metabolism of fats, cholesterol, and bile acids, participates
of the inorganic form. Selenium is stored in liver, kidneys, skeletal
in the biosynthesis of adrenal hormones, facilitates the absorption of
muscles, brain, and testis. Selenium deficiency is related to skin cancer.
nonheme iron, participates in erythropoiesis, and has also immune‐
Selenium prevents oxidative stress and damage due to oxidative stress
stimulating and bacteriostatic properties (Szyszkowska, Łepecka‐
being a cofactor of glutathione peroxidases and thioredoxin reduc-
Klusek, Kozłowicz, Jazienicka, & Krasowska, 2014).
tases and helps removing harmful lipid hydroperoxides, hydrogen
peroxide, and peroxynitrites (Gollner et al., 2017).

5.6 | Secondary metabolites (Figure 5)

5.5 | Vitamins (Figure 4)

5.6.1 | Carotenoids
5.5.1 | Vitamin E
Carotenoids are tetraterpenoid natural pigments present in fruits
Vitamin E (Figure 4) is a liposoluble vitamin with antioxidant properties and vegetable, as well as in algae and some bacteria, that protect
because of its ability to quench singlet oxygen of reactive oxygen against excessive light. Cryptoxanthin, lutein, zeaxanthin, and lyco-
species (ROS), to inactive lipid peroxide‐free radical production and pene are the most common dietary carotenoids (Ross, Caballero,
inhibit their chain reactions that damage the cells. Vitamin E deficiency Cousins, Tucker, & Ziegler, 2012). A diet high in fruit and vegetables
makes premature skin aging, keratoses difficulty in wound healing, enhances the carotenoid concentration in human skin, but it can be
irritability, reduced fertility, and ability to concentrate. (Vollmer, West, decreased by UV radiation, alcohol, and smoking. (Lademann, Meinke,
& Lephart, 2018). Sterry, & Darvin, 2011). Carotenoids are used in nutricosmetic for skin
4 DINI AND LANERI

5.7 | Plant extracts

Since ancient times, botanical extracts have been used in cosmetics

and skin care product. They are a complex mixture of natural com-
pounds with different structures and functionalities.

5.7.1 | Fermented barley and soybean mixtures

Fermented barley and soybean (Figure 6) mixtures have a synergistic

protective effect that prevents UVB‐induced skin dehydration, matrix
degradation, oxidative stress, and collagen synthesis (Oh Wook et al.,
2015).

5.7.2 | Horsetail (Equisetum arvense L.)

FIGURE 5 Secondary metabolites Horsetail (Figure 7) extracts are a source of potassium, flavonoids, and
silicon with antibacterial, have remineralizing and regenerating pro-
perties, and are very advantageous to the epidermis, hair, and nail
photoprotection against UV radiation. The combined oral and beauty. Silicon levels influence collagen biosynthesis, reinforce the
topical application of carotenoids lutein and zeaxanthin showed more blood vessel walls, reduce their permeability, and accelerate the
pronounces cutaneous hydration compared with isolated treat- wound healing process. In senile age, nail and hair brittleness and fun-
ments (Palombo et al., 2007). The combined consumption of Skin‐ gal and bacterial infections predisposition are due to low silicon levels
ProbioticTM (probiotic) and carotenoids for 6 weeks decreases (Szyszkowska et al., 2014).
UV‐induced skin damage presupplementation with a moderate
dose of β‐carotene before and during sun exposure and protects
against sunburn by decreasing significantly erythema and increasing
Langerhans cells.

5.6.2 | Astaxanthin

The astaxanthin is a xanthophyll carotenoid. Supplements based on

FIGURE 6 Barley and soy seeds [Colour figure can be viewed at
astaxanthin improve the skin fine lines/wrinkles, the age spot size,
wileyonlinelibrary.com]
the skin texture, the moisture content of the corneocyte layer, and
the skin elasticity. Moreover, the astaxanthin stimulates collagen Type
I and basic fibroblast growth factor, decreases DNA damage, inflam-
mation, and oxidative stress, and enhances the immune response
increasing natural killer cells, T cells, B cells, and IL‐6 levels (Vollmer
et al., 2018).

5.6.3 | Coenzyme Q10

Coenzyme Q10, a vitamin‐like nutrient and lipid‐soluble compound, is

formed by 10 isoprenoid units attached to benzoquinone rings. It
has three redox states (ubiquinone, semiquinone, and ubiquinol).
Coenzyme Q10 has antioxidant properties: In human fibroblasts, it
accelerates the regeneration of ATP levels after irradiation, and in
human keratinocytes, it maintains cellular energy levels. On human
skin, it prevents photoaging detrimental effects, reduces wrinkles, FIGURE 7 Horsetail (Equisetum arvense L.) [Colour figure can be
and increases skin smoothness (Vollmer et al., 2018). viewed at wileyonlinelibrary.com]
DINI AND LANERI 5

in phenolic compounds and diterpenes (carnosic acid), which are com-

ponents of oral supplements with anti‐inflammatory, photoprotective,
and antiaging effects (Figure 10). Product consumption decreases
the depth of wrinkles and increases the elasticity of the skin (Pérez‐
Sánchez et al., 2018).

5.7.6 | Red orange complex

The dietary supplements contained in 2.8–3.2% w/w anthocyanins,

8.5–9.5% w/w flavone glycosides, 1.8–2.2% w/w hydroxycinnamic
acids, and 5.5–6.5% w/w ascorbic acid are used to reduce UV‐induced
skin erythema and to ameliorate skin appearance and pigmentation
FIGURE 8 Aloe vera [Colour figure can be viewed at (Figure 11; Pérez‐Sánchez et al., 2018).
wileyonlinelibrary.com]

5.7.3 | Aloe vera (Figure 8) 5.7.7 | Polypodium leucotomos extract

Aloe gel supplementation improves collagen production and reduces Polypodium leucotomos (Figure 12) is a tropical plant related to the

collagen‐degrading MMP‐1 gene expression, enhancing wrinkles and Phlebodium genus that is found in Central and South America. It

elasticity in photoaged human skin, with no dose‐response relationship contains polyphenolic compounds (benzoic acid, cinnamic acid,

(Cho et al., 2009). Aloe sterol ingestion contributes to collagen and HA caffeic acid, and ferulic acid), monosaccharides, coumaric acid, quinic

production in human dermal fibroblasts ameliorating skin moisture, acid, shikimic acid, malic acid, glucuronic, and vanillic acid. Polypodium

trans‐epidermal water loss and, skin elasticity (Tanaka et al., 2016). leucotomos extracts supplementation decreases UV‐induced inflamma-
tory responses and UV‐mediated oxidative DNA mutations. Moreover,

5.7.4 | Pine bark (Pinus pinaster; Figure 9) oral intake accelerates removal of UV‐induced photoproducts and has
significant implications in the prevention of skin cancer (El‐Haj &
Pine bark extract supplements contain mainly flavonoids (catechins and Goldstein, 2015).
procyanidins) and phenolic acids (caffeic, ferulic, and p‐hydroxybenzoic
acids) and are able to have photoprotective effect and to increase the 5.8 | Probiotics and prebiotics
hydration and the elasticity of the skin. Their biological effects are
related to the increase of HA synthase, to the RNA expression, and to Lactococcus lactis strain supplementation improves hair follicles
gene expression involved in collagen de novo synthesis (Pérez‐Sánchez, and skin elasticity and hydration. Lactobacillus reuteri, Lactobacillus
Barrajón‐Catalán, Herranz‐López, & Micol, 2018). rhamnosus, Lactococcus lactis, and Streptococcus thermophilus supple-
mentation enhances melanin formation and minimize trans‐epidermal
5.7.5 Citrus paradisi and Rosmarinus officinalis
| water losses. Galacto‐oligosaccharides (prebiotics) supplementation
extracts increases skin hydration and cathepsin‐L‐like activity (indicator of
keratinocyte differentiation and a marker of skin barrier function;
Citrus extract, obtained from the immature grapefruits of Citrus paradisi, Lolou & Panayiotidis, 2019).
contains naringenin and rosemary extract (Rosmarinus officinalis), is rich

5.9 | Mushrooms

Several mushrooms such as Lentinula edodes, Ganoderma lucidum,

Inonotus obliquus, Grifola frondosa, and some of their metabolites are
used in nutricosmetic products to rejuvenate skin appearance (Hyde,
Bahkali, & Moslem, 2010).

6 | KEY MARKET NUTRICOSMETIC

S E GM E N T S C O V E R ED BY A P P LI CA T I O N

6.1 | Skin care

FIGURE 9 Pine bark (Pinus pinaster) [Colour figure can be viewed at Skin beauty is a multifactorial phenomenon principally determined by
wileyonlinelibrary.com] alterations of the concentration and the function of HA, collagen,
6 DINI AND LANERI

FIGURE 10 Citrus paradisi and Rosmarinus

officinalis [Colour figure can be viewed at
wileyonlinelibrary.com]

FIGURE 11 Red orange [Colour figure can

be viewed at wileyonlinelibrary.com]

and elastin fibers. Color, texture, and elasticity of the skin depend on by UV radiation, chemical oxidants, ozone, air pollutants, cigarette,
intrinsic aging due to nutritional status, on physiological factors that and microorganisms (Indo et al., 2015) able to decrease cell‐mediated
reduce the elastic fibers amount and on some extrinsic aging (photo- immunity, to increase matrix metalloproteinases (extracellular matrix
aging), which determine abnormal elastic fibers accumulation in the enzymes able to degrade collagen and elastin fibers), and to decrease
papillary dermis (Lee, Oh, & Chung, 2016; Pérez‐Sánchez et al., transforming growth factor beta, a multifunctional cytokine able to
2018). The extrinsic aging factors actions are due to ROS generated stimulate the fibroblasts in the dermis and to synthesize several
DINI AND LANERI 7

water transport along a better osmotic gradient (Puntoni et al.,

2004), within the corneocytes (moisturizing factor) and intercellular
lipids in the stratum corneum. They support the skin's barrier function,
avoid moisture water loss, prevent structural integrity of the skin
damaged by pollution and other external agent, act as anti‐
inflammatory, and inhibit the formation of corneous cells, making skin
soft and smooth (Sougrat et al., 2002; Verdier‐Sevrain & Bonte, 2007).
In‐hydrate products are formulated to ameliorate skin hydration
(Table 2; Prakash & Majeed, 2009; Oba et al., 2013; Oba et al.,
2013; Ohara et al., 2010; Shimizu et al., 2015; Tanaka, Koyama, &
Nomura, 2009; Liang et al., 2010; Zague et al., 2011).

FIGURE 12 Polypodium leucotomos [Colour figure can be viewed at

wileyonlinelibrary.com] TABLE 2 Nutricosmetics products that are useful to skin hydration

Composition Activity
proteins such as the collagen (El‐Domyati et al., 2014), the elastin, the
fibulin‐5, and proteoglycans. The collagen gives strength and flexibility Primrose oil, Vitamin E, and wheat Antioxidant
to the skin (Varani et al., 2006); the elastin and the fibulin‐5 seed extract

(Schiemann, Blobe, Kalume, Pandey, & Lodish, 2002) are important Coriander seed oil containing Antioxidant, prevent water loss,
linalool, γ‐terpinene, α‐pinene, repair lipid layers, and restore
for elastogenesis and HA producing (Ellis & Schor, 1996), whereas
p‐cymene, camphor, geranyl barrier functions.
the proteoglycans determines water retention and electrolyte acetate, and petroselinic acid
control (Westergren‐Thorsson, Schmidtchen, Särnstrand, Fransson, &
Linoleic acid, alpha‐linolenic acid, They are constituents of ceramides
Malmström, 1992). Furthermore, skin administration of antioxidants eicosapentaenoic acid, and sphingolipids present in the
is important to decrease skin aging and to protect the skin against docosahexaenoic acid stratum corneum able to avoid
harmful‐free radicals. The ROS are rapidly neutralized by chemical‐ moisture loss. Moreover, they
prevent the development of skin
free radical scavengers (Vitamins C and E and β‐carotene) and
cancer, increase skin barrier
enzymatic‐free radical scavengers (Se‐dependent gluthathione peroxi- function, decrease pruritus
dases, Cu/Zn‐superoxide dismutase, Mn‐superoxide dismutase, and elicited by dermatitis, prevent
catalase, Table 1; Steenvoorden & van Henegouwen, 1997; Thiele, UV‐induced inflammation and
hyperpigmentation, and speed
Dreher, & Packer, 2000).
up skin wound healing.
Other factors that can cause skin damage are the pollution and the
Polysaccharides (such as chitosan They prevent water loss from the
dehydration. Air pollution includes various particulate matters such as
and derivatives) skin.
nitrates, sulfates, tobacco smoke, smog, soot, house dust mite aller-
Policosanol derived from It hydrates the skin and beneficially
gens, pollen, the exhaust gas from traffic or hood, and so on, which sugarcane wax modulate sebum levels.
can be absorbed by the skin, causing local toxicity and systemic toxic-
Hyaluronic acid and collagen They increase skin firmness and
ity in other organs (Peden & Reed, 2010). The severity of these toxic- integrity, smooth out fine lines
ities depends on the age and the medical history of skin diseases. and wrinkles, and improve hair
Pollution contributes to inflammatory skin diseases (atopic dermatitis, strength and nail growth.
psoriasis, and acne), skin aging, androgenetic alopecia, skin cancer Low molecular weight glycans (e.i., It prevents water loss from the
(Guarnieri & Balmes, 2014; Song et al., 2011; Tsuji et al., 2011; Yang tamarind seed polysaccharides) skin.

et al., 2014), induces the formation of pigmented spots, the generation Diffuporine (INCI name: acetyl This peptide is able to activate the
hexapeptide‐37) human AQP3 promoter and to
of ROS, and the production of pro‐inflammatory cytokines (Kwack,
induce its protein transcription:
Ahn, Kim, Kim & Sung, 2012). Moreover, air pollutants are a high‐risk
This increases the water flux to
factor for malignant melanoma (Trueb, 2003). Concerning skin hy- the corneum stratum and
dration, it is critical to maintain skin tone and integrity. Water loss is promotes Type I collagen
regulated by the presence of natural hygroscopic agents such as aqua- synthesis and keratinocytes
proliferation that provide skin
porins, a family of small integral membrane proteins that facilitates
resiliency, strength,
compactness, and firmness,
giving an immediate and long‐
TABLE 1 Antioxidants classification (Cornelli, 2009)
lasting hydrating effect.
Class Types Action Coconut water, rich in nutrients It supports hydration and preserve
such as amino acids (arginine) skin elasticity.
Membrane or Vitamins A and E They act on collagen fibers,
lipophilic and β‐carotene elastin, and cellular Shea butter, cocoa butter, and It supports skin texture and
antioxidants structures. coconut oil derivatives hydration.
8 DINI AND LANERI

6.2 | Hair care Cho, S., Lee, S., Lee, M. J., Lee, D. H., Won, C. H., Kim, S. M., & Chung, J. H.
(2009). Dietary Aloe vera supplementation improves facial wrinkles and
elasticity and it increases the type I procollagen gene expression in
Human hair is composed by cuticle (dense outer protective layers),
human skin in vivo. Annuals in Dermatology, 21(1), 6–11. https://doi.
cortex (enclosed in the cuticle contains fibrous proteins and melano- org/10.5021/ad.2009.21.1.6
cytes that produce the pigment responsible for hair color), the Cornelli, U. (2009). Antioxidant use in nutraceuticals, USA. Clinics in Derma-
medulla (near or at the center of the hair shaft and intercellular tology, 27(2), 175–194. https://doi.org/10.1016/j.clindermatol.2008.
cement, which glues or binds the cells together and provides the main 01.010
pathway for diffusion into the hair fibers. Systemic hair care restores Costa, A. (2012). Tratado Internacional de Cosmecêuticos (primeira ed.). Rio
damaged hair and improves hair volume and growth. Essential nutri- de Janeiro: Guanabara Koogan.

ents and oxygen are transported into capillaries around the base of El‐Domyati, M., El‐Ammawi, T. S., Medhat, W., Moawad, O., Mahoney, M.
G., & Uitto, J. (2014). Expression of transforming growth factor‐beta
the bulb. Zinc, selenium, copper, molybdenum, and manganese have
after different non‐invasive facial rejuvenation modalities. Journal of
a good nutritional effect on hair. Pills containing iron, Vitamins B, D, Dermatology, 54(4), 396–404.
C, and E, proteins, and omega‐3 fatty acids are proposed to prevent El‐Haj, N., & Goldstein, N. (2015). Sun protection in a pill: the
brittleness and hair loss. photoprotective properties of Polypodium leucotomos extract. Interna-
tional Journal of Dermatology, 54, 362–366. https://doi.org/10.1111/
ijd.12611
6.3 | Nail care
Ellis, I. R., & Schor, S. L. (1996). Differential effects of TGF‐beta1 on
hyaluronan synthesis by fetal and adult skin fibroblasts: Implications
The nail plate is obtained by nail matrix keratinocytes proliferation for cell migration and wound healing. Experimental Cell Research,
and differentiation. Keratogenic nutricosmeceutics containing copper, 228(2), 326–33.14. https://doi.org/10.1006/excr.1996.0332
molybdenum, and manganese can be used to strengthen and restore Global industry analysts (2017) Nutricosmetics Market (Product type—
fingernails and toenails. Pills containing biotin are projected to Supplements (tablet, capsule, powder, and liquid) and beauty
improve the health of the nail. Supplements containing zinc, selenium, beverages/drinks; primary function—Skin care (sun care, anti‐ageing,
radiance and glow, and anti acne/pimple), hair and nail care, weight
Vitamin C, cysteine, and folic acid are proposed to ameliorate nail
management, and multifunctional; distribution channel—Modern trade,
growth. health and beauty stores, specialty stores, pharmacy stores, and e‐
commerce)—Global industry analysis, size, share, growth, trends and
forecast 2017–2025 XPLREP1863|Published On:June, 2017|No. of
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source for cosmetics. Fungal Diversity, 43, 1–9. https://doi.org/
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How to cite this article: Dini I, Laneri S. Nutricosmetics: A
Zague, V., Freitas, V., da Costa Rosa, M., de Castro, G. Á., Jaeger, R. G., &
brief overview. Phytotherapy Research. 2019;1–10. https://
Machado‐Santelli, G. M. (2011). Collagen hydrolysate intake increases
skin collagen expression and suppresses matrix metalloproteinase 2 doi.org/10.1002/ptr.6494