Tumour
Tumour
Dr.Omar A. Ajaj
Associate professor
F.I.C.M.S
The most common abdominal tumor
in infants and children
Neuroblastoma(most
common).
Renal tumors
The differential diagnosis for a malignant abdominal
mass in a child
Neuroblastoma
WT.
Hepatoblastoma.
Rhabdomyosarcoma.
Lymphoma.
WILMS TUMOR
Also referred to as nephroblastoma
or renal embryoma
WT is the most frequent tumor of
the kidney in infants and children.
One case per 10,000 infants.
Most children presenting between the ages of 1 and 4
years.
Pathology:- WTs are currently divided into those with
‘favorable’histology(90%) and those with ‘unfavorable’
histology.
Clinical Presentation and Diagnosis
WT is often noted during a bath or by doctor at a
routine visit as painless abdominal mass.
Examination:- the mass mostly not cross the
middline
This is in marked contrast to neuroblastoma,
which is frequently presents with painful
abdominal mass.
Radiographic imaging is confirm a renal origin to the
mass.
WT arise from within the kidney and distort its
internal configuration.
The treatment for WT includes operation,
chemotherapy, and in some cases, radiation therapy
(RT).
Neuroblastoma is the most common
solid extra cranial malignancy of
childhood and the most common
malignant tumor in infants.
Neuroblastoma is an embryonal tumor
of the sympathetic nervous system.
Patients with neuroblastoma
usually present with signs and
symptoms that reflect the
primary site and extent of
disease
As 75% of neuroblastoma occurs in the abdominal
cavity, an abdominal mass detected on physical
examination is a common clinical feature, as is the
complaint of abdominal pain.
The mass cross the middline.
Neuroblastoma is characterized by secretion of
catecholamine products, which can be detected in the
urine of more than 90% of patients with
neuroblastoma.
Hepatic tumors
The most common malignant hepatic neoplasms are
metastatic lesions.
Infantile hepatic hemangioma (IHH) is the most
common benign solid hepatic tumor in children.
The most common primary liver tumors occurring in
the first two years of life:-
1-Hepatoblastoma.
2-Infantile hepatic hemangioma.
TERATOMAS