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QUARTER 1
CARINA
CONCENTRATION GRADIENTS
- Ridge of cartilage at the base of the
trachea separating and opening of - Gases move from areas of high to low
the L/RMB concentration.
- In the alveoli there’s higher
BRONCHIOLES concentration of oxygen, a lower
concentration of carbon dioxide
- Smaller tubes that branch from the
compared to the deoxygenated blood
bronchi . distribute air to specific
in the capillaries
regions within the lungs
- Right lung has 3 lobes while the left
DIFFUSION ACROSS RESPIRATORY
has 2 lobes MEMBRANE
- Oxygen diffuses from the alveoli
PARTS
(where it's abundant) into the blood in
- Terminal bronchioles the capillaries, while Co2 moves from
- Respiratory bronchioles the capillaries (concentration is
- Alveoli higher) into the alveoli. The
respiratory membrane is just the
combined thickness of the alveolar
wall and the capillary wall, and it’s - Diaphragm relaxes and returns to its
extremely thin, allowing quick and dome shape moving upward into the
efficient diffusion chest cavity
- Decreases the volume of the chest
FACTORS AFFECTING GAS EXCHANGE cavity and increases the internal air
pressure
PARTIAL PRESSURE DIFFERENCES - Air is pushed out of the lungs to
- Concentration gradients for oxygen equalize the pressure
and Co2 are maintained by the - Intercostal muscles relax, allowing the
differences in partial pressures rib cage to lower, which aids in
between these gases in the alveoli and reducing chest cavity volume
the blood. Difference drives the
movement of gases
- Heart
- Lungs
SYMPTOMS
- Blood
OBSTRUCTIVE
- shortness of breath
- wheezing
HEART TRICUSPID VALVE
- The heart is a muscular organ that - Door between your right atrium and
pumps blood throughout our body via right ventricle.
an intricate network of blood vessels. AORTIC VALVE
- The heart is a double pump made up - Opens when blood flows out of your
of 4 chambers, namely, the right and left ventricle to your aorta
MITRAL VALVE
left atrium,and right and left ventricles
- Door between your left atrium and left
ATRIUM (ATRIA) ventricle.
PULMONARY VALVE
- These are thin upper cavities of the
- Opens when blood flows from your
heart from which blood is passed to
right ventricle to your pulmonary
the ventricles
arteries
LEFT ATRIUM
- The pulmonary veins delivers blood to
DEOXYGENATED BLOOD
the left atrium after the lungs infused
it with oxygen
RIGHT ATRIUM VENA CAVA
CORONARY CIRCULATION
- This type of circulation provides the
heart with oxygenated blood so it can
function properly. (to the heart)
LESSON 3
HEREDITY
- It is also known as deoxyribonucleic
acid, is the genetic material in the
cells of all organisms.
- The two scientist who are given credit
for discovering the structure of the
DNA are Francis Crick and James Visual representation of the DNA structure, genes, and chromosomes
Watson
- The structure of a DNA is a double INCOMPLETE DOMINANCE
helix/twisted ladder
- There are four monomers; adenine, NON-MENDELIAN INHERITANCE
thymine, guanine, and cytosine - Any pattern of inheritance wherein
- Two bases that are purines are; traits do not segregate following
adenine, guanine Mendel’s law.
- Two bases that are pyrimidines are; ALLELE
thymine, cytosine - Genes of the same type that contain
- The base pairs are; adenine, thymine different kinds of information.
and guanine, cytosine - Alleles can be dominant or recessive.
- Gregol mendel - father of genetics HOMOZYGOUS
- Organisms that have two identical
GENES
alleles for a particular trait. Ex. XX, YY
- These are segments of HETEROZYGOUS
deoxyribonucleic acid (DNA) that - Organisms that have two different
contain the code for a specific protein alleles – hybrids. Ex. Xx, Yy
that functions in one or more types of HOMOZYGOUS DOMINANT
cells in the body. - It has both dominant alleles for a
particular trait.
HOMOZYGOUS RECESSIVE PUNNETT SQUARE & PROBABILITY
- It has both recessive alleles for a - Used to predict the possible gene
particular trait. makeup of offspring – Punnett Square
DOMINANT - Example: Black fur (B) is dominant
- The allele of a gene that masks or to white fur (b) in mice 1. Cross a
suppresses the expression of an heterozygous male with a homozygous
alternative allele recessive female.
- A trait that masks another trait. - 2. Cross 2 hybrid mice and give the
RECESSIVE
genotypic ratio and phenotypic ratio.
- An allele that is mashed by a - Example: A man and woman, both
dominant allele. with brown eyes (B) marry and have a
GENOTYPE
blue eyed (b) child. What are the
- The genetic makeup of organisms.
genotypes of the man, woman and
PHENOTYPE
child?
- The physical appearance of an
organism.
MENDELIAN INHERITANCE
- The observable characteristics of an
- Founder: Proposed by Gregor Mendel
organism
in the 19th century.
INCOMPLETE DOMINANCE
- Principles: Based on three principles:
- It is referred to as the dilution of the
the Principle of Dominance, the
dominant allele with respect to the
Principle of Segregation, and the
recessive allele
- This pattern of inheritance in which Principle of Independent Assortment.
i IAi IBi
LESSON 5.2
i IAi IBi
SEX LINKED TRAITS
XC
Example: XcXc XcY
Draw a Punnett square which shows the
inheritance of the sex chromosomes.
Phenotype: Female colorblind carrier, Normal
male, Female colorblind, Male colorblind
Genotype: XXC, XY, XCXC, XCY ( 25% female ➢If one of its components experienced
colorblind carrier; 25% normal male; 25% changes and it doesn’t adapt to its new
female colorblind, 25% male colorblind)
environment or situation it may probably die
and lessen in numbers.
LESSON 6
BIODIVERSITY AND EVOLUTION INTERACTIONS
- Biodiversity is the term used to - When the sea otter population is
describe the number and variety of healthy and abundant, they keep the
life found on Earth. sea urchin population in check by
- Biodiversity has three types: genetic, consuming them
species, and ecosystem - When the sea urchin population is
GENETIC DIVERSITY controlled, the kelp forests flourish, as
- Refers to the variety of genetic there are fewer sea urchins to eat
ECOSYSTEM DIVERSITY
- Refers to the variety of habitats, living ADAPTATION OR DECLINE
communities, and ecological - If, for some reason, sea urchins could
processes in the living world. not adapt to an environment with less
- Examples of different ecosystems kelp (maybe there's not enough
include deserts, rainforests, alternative food sources), their
grasslands, wetlands, and coral reefs, numbers would also start to decrease
to name just a few. after initially booming.
- Each ecosystem provides habitats for - The decline in both sea otters and kelp
a unique set of species and has its could lead to a decrease in sea urchin
own processes that contribute to the numbers, even if they were initially the
planet's overall system. "winners" in the Scenario. kelp forests
➢All parts of the ecosystem are interacting sea otter sea urchin
with one another.
RICHNESS ➢ 1 represents a community with perfect
- Ribose is a sugar, like glucose, but - Rosalind Franklin and Maurice Wilkins
with only five carbon atoms in its worked with X-ray crystallography to
molecule find more clues about the structure of
- Deoxyribose is almost the same but DNA.
lacks one oxygen atom - Franklin’s X-ray images suggested a
PHOSPHATE GROUP helical structure.
- A molecule made up of phosphorus
and oxygen that plays a vital role in WATSON AND CRICK
the structure of DNA. - James Watson and Francis Crick were
THE BASES also working on discovering the
structure of DNA.
- Applied Chargaff’s rule, assumed that
A always pairs with T, C with G.
- Watson was not entirely convinced of
the helical structure that Franklin had
suggested, and his critique of her work
led her to doubt herself.
- Wilkins consulted with Watson and
COMPLEMENTARY NATURE Crick. Without Franklin’s knowledge,
he handed them the data that he and
- Adenine-Thymine Rule: Adenine
Franklin had worked on.
always pairs with thymine, forming
- Watson immediately recognized the
two hydrogen bonds.
significance. He and Crick went to
- Cytosine-Guanine Rule: Cytosine
work on a model of DNA.
always pairs with guanine,
establishing three hydrogen bonds. FUNCTION OF DNA
- It stores genetic information necessary
DNA STRUCTURE for organisms to develop, survive, and
- DNA usually consists of a double reproduce.
strand of nucleotides - Damage to DNA may cause cells to
- The sugar-phosphate chains are on stop dividing, cell death, or become
the outside and the strands are held malignant.
together by chemical bonds between
the bases THE INTERNAL STRUCTURE OF A LEAF
- The paired strands are coiled into a - Leaves have a large surface area for
spiral called A DOUBLE HELIX absorption of light, and they are also
thin which speeds up the exchange of
gases. Chloroplast
– occurs in the chloroplast specifically the – What is really absorbed are the red and
chlorophyll which is the green coloring matter blue light which in turn absorbs the light
of the leaves. energy being used.
Thylakoid
– is the internal membrane of chloroplasts
An ordinary leaf consists of the lower and and cyanobacteria, and provides the
upper epidermis, the vascular bundles platform for the light reactions of
(veins), the mesophyll, and the stomata. photosynthesis.
These parts are responsible for the following:
– the flattened interconnected sacs.
a.) Lower and upper epidermis
– the covering or protection of other parts of Stroma
the leaf. – colorless fluid surrounding the granum
within the chloroplast.
b.) Stomata
– holes in the lower epidermis where the air is Photosynthesis occurs in a two-part process.
exchanged
d.) Mesophyll
– contains the chloroplasts where
photosynthesis occurs.
LOWER EPIDERMIS
- Contains openings called stoma
(stomata).
- Carbon dioxide enters through here.
- Oxygen passes out from here.
MESOPHYLL LAYER:
- Located between the upper and lower
epidermis.
- Composed of:
1. Palisade cells: Arranged like
columns.
2. Spongy cells: Loosely arranged
cells.
- Contains organelles known as
chloroplasts. UNDERSTANDING THE FOOD-MAKING PROCESS IN PLANTS
1. Have green pigments that trap - Dive into photosynthesis, the
energy from the sun. ingenious process where plants
transform sunlight into sustenance,
powering life on Earth.
CHLOROPHYLL AND LIGHT ABSORPTION:
- Photosynthesis is initiated by the
CHLOROPLAST:
chlorophyll present in the chloroplast.
- Enclosed by a double membrane: 1. Absorbs light energy, primarily
- Outer membrane. from sunlight.
- Inner membrane. - Plant Leaf Coloration:
1. Leaves are predominantly
green because:
- Chlorophyll absorbs most colors ➢ Electrons in the reaction center become
except green. energized.
- Reflects green light, giving leaves their ➢ Energized electrons leave PSII for an
green appearance.
electron
ENTRY OF RAW MATERIALS: acceptor in the electron transport chain.
- Co2 enters and leaves via tiny ➢ To replace these electrons, water is split,
openings of the stomata resulting in:
- Water and nutrient absorption plant • Release of oxygen.
soaks up dissolved water and nutrients • Production of two hydrogen ions.
from the soil • Production of two electrons.
VASCULAR TISSUES
ELECTRON JOURNEY AND ROLE OF PS1
- Plants contain special tissues known
as vascular tissues or xylem and Electron Journey and Role of PSI:
phloem ➢ Electrons move from PSII to PSI via the
- Xylem - water electron transport chain.
- Phloem - food ➢ Hydrogen ions are pumped from the
stroma into the thylakoid by a protein in this
FORMULA FOR PHOTOSYNTHESIS
chain.
6 CO2+ 6 H2O + light energy → C6H12O6+ 6 ➢ As electrons transition between
O2 photosystems, they lose energy.
➢ PSI absorbs light to re-energize these
LIGHT DEPENDENT STAGE OF electrons.
PHOTOSYNTHESIS
➢ Chemical NADP accepts the electron and
-
hydrogen, transforming into high-energy
LOCATION AND REQUIREMENT
molecule NADPH.
- Occurs in the thylakoid membrane.
• Requires a continuous supply of
FORMATION OF ATP
light.
ROLE OF CHLOROPHYLL • Accumulated H+ ions inside the thylakoid
Absorbs light energy and converts it into are allowed to diffuse back to the stroma by
chemical energy. ATP synthase.
• Comprises two units of light-absorbing • This enzyme captures the energy of their
molecules: movement and stores it in ATP (adenosine
o Photosystem II (PSII) (1st) triphosphate).
o Photosystem I (PSI) (2nd)
BALANCING NADPH AND ATP PRODUCTION
- An enzyme in the thylakoid membrane
utilizes energy from electrons of both
PSII PSII and PSI to:
Begins when PSII receives light energy. • Produce more ATP.
➢ Light energy is transferred to a chlorophyll • Halt the generation of NADPH.
reaction center. • It's crucial to keep a balanced proportion of
NADPH and
ATP for the next phase of photosynthesis. five-carbon sugar molecule.
• The enzyme involved: Rubisco.
LIGHT DEPENDENT REACTION STAGE • The reaction results in an unstable
6-carbon molecule.
OXYGEN • This molecule splits into two 3-carbon
- Produced as a byproduct when water molecules known as 3 phosphoglyceric acid
molecules are split in the photosystem (3PGA).
II.
CO2 REDUCTION
ATP (ADENOSINE TRIPHOSPHATE) The process involves adding electrons and
- The main energy currency of the cell, energy to the carbon dioxide molecule.
produced from ADP and inorganic
phosphate via the ATP synthase • When 3PGA interacts with ATP (from the
complex as protons flow down their light-dependent reaction), it transforms into
gradient from the thylakoid lumen into biphosphoglycerate (BPGA).
the stroma. • BPGA then combines with NADPH, which
carries a high-energy electron enhanced by
NADPH
light energy and also carries a hydrogen
- Reduced form of NADP+. It is
proton.
produced when NADP+ accepts the
• NADPH donates this high-energy electron
high-energy electrons (along with a
and hydrogen to BPGA, converting it into
proton) after they pass through the
phosphoglyceraldehyde (PGAL).
photosystems.
• Carbohydrate ADP and NAD+ are sent back
to the thylakoid to be transformed again into
CALVIN CYCLE (LIGHT INDEPENDENT ATP and NADPH via the light-dependent
REACTION)
reaction.
- Location: Occurs in the stroma of the
• One of the 3PGA molecules is reserved for
chloroplast.
glucose synthesis, while the majority move on
to the next phase of the Calvin cycle.
REGENERATION OF RUBP
-
Regeneration of RuBP:
• In this phase, RuBP molecules are formed
using
Phases of the Calvin Cycle:
ATP, which then combine with the 3PGA
• Carbon Fixation:
molecules.
• Carbon dioxide (CO2) from the
• This RuBP later combines with additional
atmosphere is captured and diffuses into the
carbon dioxide molecules to eventually form
stroma.
the
•Here, it encounters RuBP
glucose molecule.
(Ribulosediphosphate), a
• The cycle turns six times, with each turn
adding
only one carbon atom from the incoming
carbon
dioxide to the glucose molecule.