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Pharmaceuticals Dosage Forms

This document discusses pharmaceutical dosage forms and drug delivery systems. It defines dosage forms as means of delivering drug molecules to sites of action in the body. It then classifies dosage forms based on route of administration (oral, topical, etc.) and physical form (solid, semisolid, liquid). Various oral solid dosage forms are described including tablets, capsules, and modified release formulations. The document provides examples of different drug delivery systems according to route of administration.

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13 views24 pages

Pharmaceuticals Dosage Forms

This document discusses pharmaceutical dosage forms and drug delivery systems. It defines dosage forms as means of delivering drug molecules to sites of action in the body. It then classifies dosage forms based on route of administration (oral, topical, etc.) and physical form (solid, semisolid, liquid). Various oral solid dosage forms are described including tablets, capsules, and modified release formulations. The document provides examples of different drug delivery systems according to route of administration.

Uploaded by

Lama Qaimari
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Pharmaceutical Dosage

Forms
Types of dosage forms:

Definition: Dosage forms are the means by which drug


molecules are delivered to sites of action within the
body.
The need for dosage forms:
1- Accurate dose.
2- Protection from gastric juice e.g. coated tablets,
sealed ampules
3- Masking taste and odour.
4- Placement of drugs within body tissues.
5- Sustained release medication.
6- Controlled release medication.
7- Optimal drug action.
8- Insertion of drugs into body cavities (rectal, vaginal)
9- Use of desired vehicle for insoluble drugs.
Types of dosage forms (Cont.):

They are classified according to:

Route of administration Physical


form
Oral Solid
Topical Semisolid
Rectal liquid
Parenteral
Vaginal
Inhaled
Ophthalmic
Otic
Dosage Form/ Drug Delivery
System by route of administration
 Oral  Sublingual
◼ Tablets ◼ Tablets
◼ Capsules ◼ Troches and
◼ Solutions Lozenges
◼ Syrups  Parenteral
◼ Elixirs ◼ Solutions
◼ Suspensions ◼ Suspensions
◼ Magmas  Conjunctival
◼ Gels ◼ Contact lens inserts
◼ Powders ‘ ◼ Ointments
Dosage Form/ Drug Delivery
System by route of administration
 Epicutaneous /  Intraocular/ intraaural
transdermal ◼ Solutions
◼ Ointments ◼ Suspensions
◼ Creams  Intranasal
◼ Infusion pumps ◼ Solutions
◼ Pastes ◼ Sprays
◼ Plasters ◼ Inhalers
◼ Powders ◼ Ointments
◼ Aerosols  Intrarespiratory
◼ Lotions ◼ Aerosols
◼ Transdermal patches,
discs, solutions
Dosage Form/ Drug Delivery
System by route of administration
 Vaginal  Rectal
◼ Solutions ◼ Solutions
◼ Ointments ◼ Ointments
◼ Emulsion foams ◼ Suppositories
◼ Gels  Urethral
◼ Tablets ◼ Solutions
◼ Inserts, ◼ suppositories
suppositories,
sponges
Solid Dosage Forms

Powders and Granules


Capsules and Tablets
Powders and Granules
 Powders
◼ Blending Powders
◼ Medicated Powders
◼ Aerosolized Powders
 Granules
◼ Effervescent
Capsules
 Hard Gelatin Capsules
 Soft Gelatin Capsules
Hard Gelatin Capsules
Tablets
 Compressed tablets  Chewable Tablets
(C.T.)  Effervescent Tablets
 Multiple Compressed  Molded Tablets
tablets (M.C.T.)  Immediate release
 Sugar-Coated Tablets Tablets (I.R.)
(S.C.T.)  Instant Disintegrating
 Film Coated Tablets /Dissolving Tablets
(F.C.T)  Extended release
 Gelatin Coated Tablets Tablets (E.R.)
 Enteric Coated Tablets  Vaginal Tablets
(E.C.T.)
 Buccal or Sublingual
Tablets
Compressed Tablets contains:

 Medicinal agent
 Diluents or filler
 Binders or
adhesives
 Disintergrants
 Lubricants
 Miscellaneous
adjuncts
◼ Colorants and
flavorants
Tablets

Compressed tablets Multiple Compressed tablets Sugar-Coated Tablets Film Coated Tablets

Gelatin Coated Tablets Enteric Coated Tablets


Modified-Release Dosage Forms
and Drug Delivery Systems
 Modified Release  Terminology of
 Extended Release extended release
◼ Sustained Release (SR)
 Delayed Release
◼ Sustained Action (SA)
 Repeat action
◼ Prolonged Action (PA)
 Targeted Release ◼ Controlled Release (CR)
◼ Extended Release (ER)
◼ Timed Release (TR)
◼ Long Acting (LA)
Modified Release
Extended Release
Delayed Release
Controlled Release (CR) &
Sustained Release (SR)
-Extended Release

%
Timed Release (TR)
Modified-Release Dosage Forms
Example of oral control release
capsule

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