Asynch - Task - Sciences - LEPT Competency-Based Reviewers
Asynch - Task - Sciences - LEPT Competency-Based Reviewers
AREA 1: BIOLOGY
1. Plant and Animal Biology (℅: DR. NIKKO)
1.1. Demonstrate familiarity with the classification of plants and animals and their basic needs
for survival
1.2. Show how plants and animals maintain homeostasis and energy acquisition for
sustainability
● Plants perform photosynthesis using its organelle – chloroplast, which contains the green
pigment known as chlorophyll which captures light energy.
● Animals depend on their food/diet to other organisms.
● Both plants and animals perform cellular respiration via mitochondria to produce energy in
the form of adenosine triphosphate (ATP).
● Animals and Plants have cell transport systems that allow them to maintain the balance
between and amongst cells: Diffusion, Osmosis, and Active Transport.
2. Genetics (VILLAR)
2.1. Illustrate the roles of chromosomes and genes in genetic technology
● Genetic technology is the term given to a range of activities concerned with understanding
gene expression, taking advantage of natural genetic variation, modifying genes and
transferring genes to new hosts. It provides medical assistance and treatment to alter
abnormalities or developing diseases due to occurrence of mutation during replication.
● Chromosomes are thread-like structures that carry hereditary information in the form of
genes, definitely genes made up of DNA which are completely and tightly packaged within
the nucleus and also called itself as a genome. Living organisms do not have no the same
numbers of chromosomes such as humans with 23 pairs of chromosomes, dogs with 78
grand total of chromosomes, cats with 19 pairs of chromosomes etc. Every pair of
chromosomes must have correct genetic codes and properly arrange before it undergoes the
process called cell division. If there are issues occurring, it will probably jump to mutation, but
with the help of technology there are many chances to change the particular issues that
make up solutions for genetic disorders and diseases. Genetic Technology presented by
many professional scientists to look what’s the best alternative solution to resolve the
particular issues such chromosomes and genes carrying disorder may no longer be passed
and come out in another generation.
2.2. Identify the benefits, derived from genetic technology in the fields of medicine and
agriculture
● To prevent developing symptoms or disease brought by the viruses and other pathogens.
● Protection for any types of dangerous disease like polio, measles, smallpox and some
infections.
● Provide protection against Sexual Transmitted Diseases.
● To produce healthy vitamins that everyone can take orally.
● Boosting immunity.
● To provide treatment for diseases that come from mutation such as cancer, hemophilia,
leukemia, and genetic disorders.
● To improve drugs against biotic drug resistant and viral diseases.
● Production of clean cow’s milk that can be drunk even if the person has lactose intolerance.
● Reduce the use of pesticides.
● Reduce the use of fertilizer with higher cost.
● Provide protection to crops, vegetables and fruits against attackers such as bugs, bacteria,
fungi and parasites.
● Enhance food nutrients and quality.
● Increased tolerance to various biotic and abiotic stresses.
● Increased supply of food with reduced cost and longer shelf life.
● Faster growing plants and animals.
● Disease and drought-resistant plants that require fewer environmental resources.
● WHAT IS CELL?
-Cells are the basic building blocks of all living things.
- Structural and fundamental units of life.
- Complexes and their components perform various functions in organisms.
- Cells have many parts called organelles used as specialized structures that perform certain
tasks.
***Organelles
1. Cell Membrane, Nucleus, Mitochondria, Endoplasmic Reticulum, Golgi Apparatus,
Lysosomes, Vacuoles, Cytoplasm, Chloroplasts, Peroxisome
***Sub-organelles
1. Centrosomes, Ribosomes, Cilia and Flagella, Centrioles
● WHAT IS MOLECULE?
- a group of atoms bonded together, representing the smallest fundamental unit of a chemical
compound that can take part in a chemical reaction.
- It made up of one or more atoms
- They can vary greatly in size and complexity.
3.2. Exhibit the characteristics and functions of the cell as the fundamental unit of life
● The cell is the basic structural and functional unit of life. Cells are independent, single-celled
organisms that take in nutrients, excrete wastes, detect and respond to their environment,
move, breathe, grow, and reproduce. The macromolecules carbohydrates, proteins, lipids,
and nucleic acids make up all of the structural and functional units of cells.
1. cellular organization- This simply means that living things are made of cells. Cells are the
most basic unit of life.
2. reproduction- If something is alive it must be capable of reproducing. Multicellular life forms
such as humans reproduce sexually, while unicellular life forms like bacteria reproduce
asexually. (Mitosis and Meiosis)
3. Metabolism- is essentially a collection of chemical reactions occurring within the body (or
cell). These reactions vary in form and function but promote processes such as protein
synthesis, chemical digestion, cell division, or energy transformation.
4. Homeostasis- is the term used to describe maintaining a stable internal environment. In
other words, think about how our bodies maintain a constant body temperature or how
blood sugar levels are consistent.
5. Heredity - means that our genetic information can be passed from one generation to
another. (DNA Replication)
6. Response to stimuli- is the next characteristic in our countdown. This is simply a reaction
to an internal or external force. (Human reactions, Plant Tropism)
● Bacteria ● Protists
● Archaea ● Viruses
● Fungi ● Microscopic Animals
- Some microbes make us sick, others are important for our health.
Common Microbes
VIRUS
Common Name: Hanta Virus
Scientific Name: Orthohanta
Pathogenic Diseases(s) and its short description:
Hantavirus is spread when virus-containing particles from
rodent urine, droppings, or saliva are stirred into the air.
PROTIST
Common Name: Meliodosis- Whitmore's disease
Scientific Name: Burkholderia pseudomallei
Pathogenic Diseases(s) and its short description:
Most people infected with B. pseudomallei experience no
symptoms, but those who do experience symptoms have
signs and symptoms that range from mild, such as fever,
skin changes, pneumonia, and abscesses, to severe
with inflammation of the brain, inflammation of the joints,
and dangerously low blood pressure that causes death.
Common Name: Toxoplasmosis
Scientific Name: Toxoplasma gondii
Pathogenic Diseases(s) and its short description:
A toxoplasma gondii is an intracellular protozoan parasite
that is found in contaminated food and water, animal feces
and undercooked meat. Once a person becomes infected
they will experience certain infections such as
toxoplasmosis, form cysts that affect your internal organs,
and weaken your immune system.
FUNGI
NEMATODES
Common Name: Oriental lung fluke
● WHAT IS A DISEASE?
- A disease is an abnormal condition affecting a living organism. Diseases are generally understood
to be medical conditions that involve a pathological process associated with a specific set of
symptoms.
- The diseases causing microorganisms include bacteria, viruses, protozoa, fungi and a few variations
of worms.
- Once they invade the host cell, they disrupt or damage the normal cellular activities. This leads to
diseases on a larger scale.
● Diseases Caused By Microorganisms
-Viral diseases are caused by viruses. These include both acute and infectious diseases like the
common cold, to chronic disease like AIDS. Apart from these acute diseases, viruses are also
responsible for mumps, polio, rabies etc.
-Diseases caused by bacteria include diphtheria, typhoid, cholera etc.
-Malaria and sleeping sickness are diseases caused by protozoa.
-Worms like roundworms, tapeworms could cause diseases like Ascariasis and Taeniasis
respectively.
● Types of Host
Fomite - A fomite refers to inanimate objects that can carry and spread disease and infectious agents.
Fomites can also be called passive vectors.
Living Host - a living animal or plant on or in which a parasite lives.
4.2. Distinguish bacteria, protists, and viruses and their effects on humans
● Viruses
- Viruses can be seen only through an electron microscope. They are inactive outside a living cell.
- Once they are inside the host body, they take over the entire cellular activities of the organism. They
cannot be destroyed by antibiotics.
- Common cold, measles, mumps, smallpox are some of the diseases caused by viruses.
● Bacteria
- Bacteria are microscopic, single-celled organisms that exist in their millions, in every environment,
both inside and outside other organisms.
- Not all bacteria cause diseases. The bacteria that infects an organism produces toxins that can
cause diseases.
- Cholera, tuberculosis, and anthrax are caused by bacteria. These can be killed by antibiotics.
● Protists
- simple eukaryotic organisms that are neither plants nor animals or fungi. Protists are unicellular in
nature but can also be found as a colony of cells.
- Protozoans such as amoeba cause diseases such as amoebic dysentery. Malaria and sleeping
sickness is also caused by protozoans.
DERMIS
- Supports epidermis. Contains nerve endings, blood
vessels, and smooth muscles.
- Assist in thermoregulation, and aid in sensation
Papillary Dermis- The papillary dermis has connective
tissue and blood vessels that give nutrients to the epidermis
and help control the temperature of the skin.
Reticular Dermis- Is denser than the papillary dermis, and it
strengthens the skin, providing structure and elasticity.
It also supports other components of the skin, such as hair
follicles, sweat glands, and sebaceous glands.
2 types of glands
A) Sweat glands - controlled by nervous system
B) Sebaceous glands - produce oily secretions that help keep the epidermis flexible and waterproof.
HYPODERMIS/SUBCUTANEOUS TISSUE
- Located beneath the Dermis.
- It’s a layer of connective tissue made of fat.
- It’s a shock absorber, insulator, and energy storage.
- Anchors skin to underlying organs.
- Thickness varies throughout the body.
● Hair
- Aids in regulating body temperature.
- Filters out dust and dirt .
- Sensitive to movement
- Absorbs radiation from the sun that may be harmful.
- Mechanical protection for the skin increases sensory function.
● Nails
- To reinforce and protect the ends of the fingers and
toes. Sweat glands are exocrine glands that secrete
water and salt from the skin or hair.
COMMON DISEASES
● Acne
- Is a disorder of the hair follicles and sebaceous glands
that become clogged.
This leads to pimples and cysts.
- Acne is a common condition that usually begins during
puberty because of hormonal changes.
Acne can be either superficial or deep.
Cause:
Occurs when the opening of hair cells are blocked by dead
epidermal cells.
The oil from the sebaceous glands gets trapped and bacteria that live in your skin
build up and cause irritation that leads to inflammation
Treatment:
Acne treatments work by reducing oil production, speeding up skin cell turnover, fighting bacterial infection,
and reducing the inflammation of the affected area.
Each pore opens to a follicle. A follicle contains a hair and an oil gland. The oil released by the gland helps
remove old skin cells and keeps your skin soft.
When glands produce too much oil, the pores can become blocked and dirt, bacteria, and cells build up.
The blockage is called a plug or comedone.
If the top of the plug is white,
It is called a whitehead.
If the top of the plug is dark,
It is called a blackhead.
If the plug breaks open, swelling and red bumps occur.
● Psoriasis
Treatment
Topical treatments
Creams and ointments applied directly to the skin can be helpful for reducing mild to moderate psoriasis.
Topical psoriasis treatments include: Topical corticosteroids, Topical retinoids, Anthralin, Vitamin D
analogues, Salicylic acid and Moisturizer
Systemic medications
People with moderate to severe psoriasis, and those who have not responded well to other treatment types,
may need to use oral or injected medications.
Many of these medications can have severe side effects, and for that reason, doctors usually prescribe them
for short periods of time. These medications include: Methotrexate, cyclosporine (Sandimmune), Biologics
and Oral retinoids.
Light therapy
This psoriasis treatment uses ultraviolet (UV) or natural light. Sunlight kills the overactive white blood cells
that are attacking healthy skin cells and causing rapid cell growth. Both UVA and UVB light may be helpful in
reducing symptoms of mild to moderate psoriasis.
Bones are where new blood cells are generated (in the marrow), and require the mineral calcium for strength.
Osteocytes - cells that build and maintain bones.
There are 206 bones in an adult human skeleton.
● Radius and Ulna (Lower arm) -The radius and ulna refer to
the bones in your forearm that connect your wrist to your
elbow. The radius connects to the thumb side of your wrist and
is the larger of the two while the ulna connects to the pinky side
and is the smaller one.
● Cranium (Skull) -The bones that form the head. Is also made up
of cranial bones (bones that surround and protect the brain) and
facial bones (bones that form the eye sockets, nose, cheeks, jaw,
and other parts of the face).
Body System and Components and Common Diseases (at Ways of taking good
General Functions Specific Function least 2) care
2. Skeletal System
● Osteoporosis -Eats a lot of
● ● Sternum vegetables because
(breastbone) - It is a condition
where bones they’re one of the best
Cell Type: -Is a partially sources of vitamin C,
T-shaped vertical become thin and
lose their strength, which stimulates the
bone that forms the production of
anterior portion of the as they become
less dense and bone-forming cells. C’s
chest wall centrally. antioxidant effects may
their quality is
reduced. This can protect bone cells from
lead to broken damage Vegetables
bones, which also seem to increase
cause pain, bone mineral density.
disability, and
make everyday Perform Strength
activities Training and
extremely difficult. Weight-Bearing
Cause Exercises can help
increase bone
● Clavicle Bone structure and formation during bone
(shoulder body weight. growth and protect
blade) Petite and thin people bone health in older
-Is the bone that have a greater risk of adults, including those
connects the developing osteoporosis with low bone density.
breastplate (sternum) because they have less
to the shoulder. It is a bone to lose than people Consume Enough
very solid bone that with more body weight Protein a low protein
has a slight S-shape. and larger frames. intake can lead to bone
loss, while a high
protein intake can help
Treatment protect bone health
Treatments for during aging and
established osteoporosis weight loss.
may include exercise,
vitamin and mineral Eat High-Calcium
supplements, and Foods because it is the
medications. Exercise main mineral found in
and supplementation are bones and must be
often suggested to help consumed every day to
you prevent osteoporosis. protect bone health.
● Fibula and
Tibia (calf) Weight-bearing,
resistance and balance Getting Plenty of
-The tibia is a larger
exercises are all Vitamin D and
bone on the inside
important. Vitamin K for
much thicker than the
adequate amounts of
fibula while Fibula is a
vitamins D and K2 from
smaller bone on the
food or supplements
outside.
may help protect bone
health.
Maintaining a Stable,
Healthy Weight
because being too thin
or too heavy can
negatively affect bone
health. Furthermore,
maintaining a stable
weight, rather than
repeatedly losing and
regaining it, can help
preserve bone density.
● Vertebrae
(back)
- Protect and support
the spinal cord. They
also bear the majority
of the weight put upon
your spine. The body ● Scoliosis
of each vertebra is the - Is an abnormal
large, round portion of lateral curvature of
bone. the spine. It is
most often
diagnosed in
childhood or early
adolescence. The
spine's normal
curves occur at
the cervical,
thoracic and
lumbar regions in
the so-called
“sagittal” plane.
● Scapula
(shoulder)
-Also called the
shoulder blade, either
of two large bones of
the shoulder girdle in
vertebrates. In
humans they are
triangular and lie on
the upper back
between the levels of
the second and eighth
ribs.
Cause
Neuromuscular
conditions:
These conditions affect
the nerves and muscles.
They include cerebral
palsy, poliomyelitis, and
muscular dystrophy.
Congenital scoliosis:
● Pelvic bone Congenital means that
- Pelvis, also called the condition was present
bony pelvis or pelvic at birth. Scoliosis is rare
girdle. Basin-shaped at birth, but it can occur if
complex of bones that the bones in the spine
connects the trunk develop abnormally when
and the legs, supports the fetus is growing.
and balances the
trunk, and contains Specific genes:
and supports the Researchers believe that
intestines, the urinary at least one gene plays a
bladder, and the role in the development of
internal sex organs. scoliosis.
Leg length:
If one leg is longer than
the other, an individual
may develop scoliosis.
Syndromic scoliosis:
Scoliosis can develop as
part of a medical
condition, including
neurofibromatosis or
● Coccyx (tail Marfan’s syndrome.
bone)
-Triangular bony Osteoporosis:
structure located at Osteoporosis can cause
the bottom of the secondary scoliosis due
vertebral column. It is to bone degeneration.
composed of three to
five bony segments Other causes:
held in place by joints Poor posture, carrying
and ligaments backpacks or satchels,
connective tissue
disorders, and some
injuries can cause spinal
curvature.
Treatment
Braces
Wearing a brace won't
cure scoliosis or reverse
the curve, but it usually
prevents the curve from
getting worse.
Surgery
Surgical options include:
Spinal fusion
In this procedure,
surgeons connect two or
more of the bones in the
spine (vertebrae) together
so they can't move
independently. Pieces of
bone or a bone-like
material are placed
between the vertebrae.
Expanding rod
If the scoliosis is
progressing rapidly at a
young age, surgeons can
attach one or two
expandable rods along
the spine that can adjust
in length as the child
grows.
Healthy Bones
Bone health and
muscle health go
hand-in-hand, and
much like muscles,
A muscle strain is an your bones respond to
injury in which muscle weight-bearing
fibres tear as a result of exercise by becoming
overstretching. A muscle denser and stronger.To
strain is also commonly keep your bones
called a pulled muscle or healthy, get plenty of
2. Smooth muscle - torn muscle. (Strains are exercise, avoid
Internal organs often confused with smoking and consume
(except heart), one sprains, which are similar a diet rich in calcium
nucleus, nonstriated, injuries to ligaments.) and potassium.
involuntary control. Depending on the degree
of injury to muscle fibres, Hormonal Balance
a muscle strain can range
from mildly to extremely Aside from diet and
And also these painful. Besides pain, exercise, your muscle
muscles line the typical symptoms include mass (and bone mass)
insides of organs such stiffness and bruising in are heavily regulated
as the bladder, the area of the strained by your hormone
stomach and muscle. The photo here levels. Estrogen,
intestines. Smooth shows a large bruise testosterone and
muscles play an caused by a hamstring thyroid hormones all
important role in many muscle strain. Hamstring play a role, and it’s
body systems, strains are very common important that you keep
including the female in track and field athletes. these hormones in
reproductive system, In sprinters, for example, balance as you age.
male reproductive about one third of injuries
system, urinary are hamstring injuries. Anti-Inflammatory
system and Having a previous Foods
respiratory system. hamstring injury puts an
These types of athlete at increased risk Acute inflammation is
muscles work without for having another one. your body’s normal
you having to think response to hard
about them. Proper first aid for a exercise and other
muscle strain includes forms of stress.
five steps, which are Chronic inflammation,
represented by the however, is painful and
acronym PRICE. The potentially damaging to
PRICE steps should be muscle tissue.
followed for several days Fortunately, you may
after the injury. The five be able to stave off
steps are: inflammation with
1. Protection: Apply certain
soft padding to the anti-inflammatory
strained muscle to foods, including leafy
minimize impact green vegetables, olive
with objects that oil, nuts and berries. It
3. Cardiac muscle- might cause also helps to avoid
Heart, one nucleus, further damage. pro-inflammatory foods
striated, involuntary 2. Rest: Rest the such as refined sugar,
control. muscle to trans fats and
accelerate healing processed grains.
And these muscles and reduce the
line the heart walls. potential for Cutting Back on
They help your heart re-injury. Alcohol
pump blood that 3. Ice: Apply ice for reducing your alcohol
travels through your 20 minutes at a consumption can have
cardiovascular time every two a major impact on your
system. You don’t hours to reduce strength and longevity.
control cardiac swelling and pain. Alcohol tends to cause
muscles. Your heart 4. Compression: an inflammatory
tells them when to Apply a stretchy response, and can
contract. bandage to the make it more difficult
strained muscle to for your body to digest
reduce swelling. and absorb nutrients
from food. Even a few
5. Elevation: Keep drinks can cause
the strained dehydration if you’re
muscle elevated not vigilant about
to reduce the drinking enough water,
chance of blood which can lead to
pooling in the muscle pains and
muscle. cramps.
Non-steroidal
anti-inflammatory drugs
(NSAIDs, such as
ibuprofen) can help
reduce inflammation and
Structure: relieve pain. Because
such drugs interfere with
Tendons- Dense blood clotting, however,
strips of connective they should be taken only
tissue. after bleeding in the
Flexor- Muscles that muscle has stopped —
cause a joint to bend. not immediately after the
Extensor- Muscles injury occurs. For severe
that cause the joint to muscle strains,
straighten. professional medical care
Actin & Myosin- may be needed.
Enable muscles to
contract.
Myofibrils- A fiber
found in straighten
muscle cells and that
is responsible of
muscle contractions.
Sarcomere- Basic
unit of contraction in
skeletal and cardiac
muscles.
Origin- Muscle pulls
against origin.
Insertion- Bone that
moves when muscle
contracts.
- Biceps,triceps
Deltoids, Glutes and
Hamstrings.
4. Digestive System Major Organs and Gastroesophageal Restrict Alcohol
their Functions: Reflux Disease (GERD) Intake: Alcohol is a
● to convert food depressant and
particles into Mouth – to chew and relaxant, and it
simpler grind up food increases the acid
macromolecule content in the
s that can be -- saliva also begins stomach so should be
absorbed into the chemical used in moderation.
the breakdown
bloodstream
Keep a Diary: Keep a
and used by Esophagus – pipe
daily log of the food
the body. connecting mouth to
GERD (gastroesophageal you eat and any
● breaks stomach
nutrients into reflux disease, or chronic symptoms you
parts small Stomach – secretes acid reflux) is a condition experience to help
enough for an extraordinarily in which acid-containing you identify triggers.
your body to strong acid (pH = 2) contents in your stomach As triggers are not
absorb and that leads to persistently leak back up always food related,
use for energy, breakdown of food into your esophagus, the be sure to include
growth, and tube from your throat to other potential triggers
cell repair. -- once the food is your stomach. such as stress and
● broken down in the poor sleep.
Acid reflux happens
stomach and mixed
because a valve at the
with digestive juices, it De-Stress: The gut
end of your esophagus,
is called chyme and brain are closely
the lower esophageal
sphincter, doesn’t close connected so excess
Pancreas – secretes stress can cause the
properly when food
digestive enzymes, digestive system to go
arrives at your stomach.
produces the hormone into overdrive.
Acid backwash then flows
insulin that regulates Practice relaxation
back up through your
blood sugar levels techniques, such as
esophagus into your
throat and mouth, giving deep breathing
-- also help neutralize
you a sour taste. exercises, daily to
stomach acid
reduce stress.
Liver – produces bile, What are the main
which breaks down symptoms of GERD Exercise: Regular
fats in foods (chronic acid reflux)? exercise triggers
muscle contractions in
The main symptoms are the large intestine
Gallbladder –
persistent heartburn and which speeds up the
pouch-like organ that
acid regurgitation. Some movement of food.
stores bile for future
people have GERD This reduces the level
use
without heartburn. of water lost from
Instead, they experience
Small Intestine – after stools as they travel
pain in the chest,
digestion is complete, through the intestine,
hoarseness in the
the chyme enters the and keeps stools soft
morning or trouble
small intestine where and easy to pass.
swallowing. You may feel
it is absorbed into the
like you have food stuck
bloodstream Stop Eating When
in your throat, or like you
are choking or your throat You Feel Full: It can
-- the chyme is is tight. GERD can also take up to 20 minutes
propelled along by cause a dry cough and for your brain to
folded surfaces called bad breath. receive signals from
villi, on the intestine your stomach telling it
How common is GERD that you are full, so
Large Intestine – (chronic acid reflux)? eat slowly. A good
removes water from way to achieve this is
the chyme and gets GERD is very common. to ensure you chew
the waste ready for The condition and its your food around 30
excretion symptoms touch a huge
times per mouthful.
number of people: 20% of
the U.S. population.
Add Fibre to Your
Anyone of any age can Diet: Fibre slows the
develop GERD, but some absorption rate of
may be more at risk for it. foods and so provides
For example, the chances a steady release of
you’ll have some form of energy, rather than
GERD (mild or severe) sudden peaks and
increase after age 40. crashes in energy.The
best dietary sources
You’re also more likely to of fibre are
have it if you’re: vegetables, fruits, and
beans.
● Overweight or
obese.
Add Probiotics:
● Pregnant.
● Smoking or are Probiotics such as
regularly exposed Acidophilus help to
to second-hand balance ‘good'
smoke. bacteria within the
● Taking certain digestive tract, and
medications that improve the
may cause acid functioning of the
reflux. digestive system.
● Heartburn.
● Regurgitation
(food comes back
into your mouth
from the
esophagus).
● The feeling of food
caught in your
throat.
● Coughing.
● Chest pain.
● Problem
swallowing.
● Vomiting.
● Sore throat and
hoarseness.
● Frequent small
vomiting episodes.
● Excessive crying,
not wanting to eat
(in babies and
infants).
● Other respiratory
(breathing)
difficulties.
● Frequent sour
taste of acid,
especially when
lying down.
● Hoarse throat.
● Feeling of choking
that may wake the
child up.
● Bad breath.
● Difficulty sleeping
after eating,
especially in
infants.
-Chronic diarrhea
Chronic diarrhea is
defined as loose stools
that last for at least four
weeks. This usually
means three or more
loose stools per day.
There are many possible
causes of chronic
diarrhea. Treatment is
aimed at correcting the
cause of diarrhea
(whenever possible),
firming up loose stools,
and dealing with any
complications of diarrhea.
Chronic diarrhea can
have a substantial impact
on your quality of life and
overall health. At its
mildest, diarrhea is an
inconvenience; at its
worst, it may be disabling
and even life threatening.
Fortunately, effective
treatments are available.
CHRONIC DIARRHEA
CAUSES
Inflammatory bowel
disease — There are
several types of
inflammatory bowel
disease, two of the most
common of which are
Crohn disease and
ulcerative colitis. These
conditions may develop
when the body's immune
system attacks parts of
the digestive tract. A clue
to the presence of
inflammatory bowel
disease is the presence
of blood in the stool.
Infections — Intestinal
infections are a cause of
chronic diarrhea.
Infections that cause
chronic diarrhea can be
seen in people who travel
or live in tropical or
resource-limited
countries. Intestinal
infections can also
develop after eating
contaminated food or
drinking contaminated
water or unpasteurized
("raw") milk.
Endocrine disorders —
An overactive thyroid
(hyperthyroidism) can
cause chronic diarrhea
and weight loss. Diabetes
can cause chronic
diarrhea if the nerves that
supply the digestive tract
are injured.
Food allergy or
sensitivity — Food
allergies and
hypersensitivity can
cause chronic diarrhea.
People with celiac
disease are sensitive to
gluten, a major
component of wheat flour
which can cause diarrhea
and weight loss. Patients
with lactose intolerance
develop diarrhea and gas
when they ingest milk.
Medicines — Medicines
(prescription and
nonprescription), herbs,
and dietary supplements
can cause diarrhea as a
side effect. To determine
if a medicine could be the
cause of your diarrhea,
review your list of
medicines with your
doctor, nurse, or
pharmacist. This
information may also be
available on the medicine
bottle or paperwork that
comes with most
prescriptions.
5. Circulatory Heart Attack Maintain a healthy
System The parts of your weight.
circulatory system are
● to deliver your: Don’t smoke.
oxygenated
blood to the ● Heart, a Exercise a minimum of
various cells muscular 30 minutes a day, most
and organ organ that days of the week.
systems in pumps blood
your body so throughout Maintain a healthy,
they can your body. low-fat, low-cholesterol
undergo ● Blood diet with more fruits,
cellular vessels, which vegetables, and whole
respiration include your grains.
● Circulates arteries, veins
OXYGEN and and capillaries. A heart attack occurs Avoid trans fats and
removes ● Blood, made when the flow of blood to saturated fats, which
Carbon up of red and the heart is severely are often found in
Dioxide. white blood reduced or blocked. The processed foods and
● Provides cells cells, plasma blockage is usually due to fast food.
with and platelets. a buildup of fat,
NUTRIENTS. cholesterol and other Limit salt and alcohol
● Removes the There are three main substances in the heart intake.
waste products types of blood (coronary) arteries. The
of metabolism vessels: fatty, Use relaxation and
to the cholesterol-containing self-care to reduce
● Arteries: deposits are called
excretory stress.
Arteries are plaques. The process of
organs for
thin, muscular plaque buildup is called
disposal.
tubes that atherosclerosis.
● Protects the
carry Sometimes, a plaque can
body against
oxygenated rupture and form a clot
disease and
blood away that blocks blood flow. A
infection.
from the heart lack of blood flow can
● Clotting stops
and to every damage or destroy part of
bleeding after
part of your the heart muscle.
injury.
body. The A heart attack is also
●
aorta is the called a myocardial
body’s largest infarction.
artery. It starts Prompt treatment is
at the heart needed for a heart attack
and travels up to prevent death. Call 911
the chest or emergency medical
(ascending help if you think you might
aorta) and then be having a heart attack.
down into the
stomach
(descending Symptoms
aorta). The Symptoms of a heart
coronary attack vary. Some people
arteries branch have mild symptoms.
off the aorta, Others have severe
which then symptoms. Some people
branch into have no symptoms.
smaller Common heart attack
arteries symptoms include:
(arterioles) as
they get farther ● Chest pain that
from your may feel like
heart. pressure,
● Veins: These tightness, pain,
blood vessels squeezing or
return aching
oxygen-deplet ● Pain or discomfort
ed blood to the that spreads to the
heart. Veins shoulder, arm,
start small back, neck, jaw,
(venules) and teeth or
get larger as sometimes the
they approach upper belly
your heart. ● Cold sweat
Two central ● Fatigue
veins deliver ● Heartburn or
blood to your indigestion
heart. The ● Lightheadedness
superior vena or sudden
cava carries dizziness
blood from the ● Nausea
upper body ● Shortness of
(head and breath
arms) to the
heart. The High Blood Pressure
inferior vena
cava brings
blood up from
the lower body
(stomach,
pelvis and
legs) to the
heart. Veins in
the legs have
valves to keep
blood from
flowing
backward.
● Capillaries:
These blood
vessels
connect very
small arteries
High blood pressure, also
(arterioles) and
called hypertension, is
veins
blood pressure that is
(venules).
higher than normal. Your
Capillaries blood pressure changes
have thin walls throughout the day based
that allow on your activities. Having
oxygen, blood pressure measures
carbon dioxide, consistently above normal
nutrients and may result in a diagnosis
waste products of high blood pressure (or
to pass into hypertension).
and out of
cells. The higher your blood
pressure levels, the more
risk you have for other
health problems, such as
heart disease, heart
attack, and stroke.
Chronic obstructive
pulmonary disease
(COPD)
Emphysema develops
when the tiny air sacs in
the lungs (alveoli)
become damaged and
less elastic. This reduces
the ability of the sacs to
move oxygen and other
gases between the air
that is breathed in and the
blood. This can lead to a
lack of oxygen in the
blood (hypoxia) and a
buildup of toxic waste
products.
Chronic bronchitis is a
condition where the lining
of the bronchial tubes
becomes irritated and
inflamed. The swelling
can make it more difficult
to breathe and cause an
overproduction of mucus.
Symptoms
● A frequent or
chronic cough
● A cough that
produces a lot of
mucus
● Wheezing
● A squeaking or
whistling sound
when you breathe
● Shortness of
breath that is
worse with activity
● Tightness in your
chest
● Sensitivity to
respiratory
infections like
colds or the flu
● Weight loss
● Weakness
● Swelling in your
legs and feet
● A blue tinge to
your lips or
fingernails
(cyanosis)
Diagnosis
Health care professionals
use your medical history,
a physical exam, and
tests to diagnose kidney
stones. The tests may
also be able to show
problems that caused a
kidney stone to form.
Treatment
Health care professionals
may treat your kidney
stones by removing the
kidney stone or breaking
it into small pieces. You
may be able to prevent
kidney stones by drinking
enough water, changing
the way you eat, or taking
medicines.
Scrotum
Epilepsy
Epilepsy is a long-term
brain condition where a
person has repeated
seizures. It is thought to
affect about 3 in every
100 Australians.
to control growth,
development, Get plenty of exercise.
metabolism and
reproduction through Eat a nutritious diet.
the production and
secretion of hormones Go for regular medical
checkups.
Sends Hormones into Diabetes mellitus,
Your Bloodstream. Talk to the doctor
commonly known as before taking any
diabetes, is a metabolic supplements or herbal
Regulates the Release disease that causes high
of Hormones. treatments.
blood sugar. The
hormone insulin moves Let the doctor know
sugar from the blood into about any family history
your cells to be stored or of endocrine problems,
used for energy. With such as diabetes or
diabetes, your body either thyroid problems.
doesn’t make enough
insulin or can’t effectively
When Should I Call
use the insulin it does
the Doctor?
make.
Let the doctor know if
you:
Untreated high blood
sugar from diabetes can drink a lot of water but
damage your nerves, are still thirsty
eyes, kidneys, and other
organs. have to pee often
Hyperthyroidism
(overactive thyroid)
occurs when your thyroid
gland produces too much
of the hormone thyroxine.
Hyperthyroidism can
accelerate your body's
metabolism, causing
unintentional weight loss
and a rapid or irregular
heartbeat.
Symptoms
Hyperthyroidism can
mimic other health
problems, which can
make it difficult for your
doctor to diagnose. It can
also cause a wide variety
of signs and symptoms,
including:
● Unintentional
weight loss, even
when your
appetite and food
intake stay the
same or increase
● Rapid heartbeat
(tachycardia) —
commonly more
than 100 beats a
minute
● Irregular heartbeat
(arrhythmia)
● Pounding of your
heart (palpitations)
● Increased appetite
● Nervousness,
anxiety and
irritability
● Tremor — usually
a fine trembling in
your hands and
fingers
● Sweating
● Changes in
menstrual patterns
● Increased
sensitivity to heat
● Changes in bowel
patterns,
especially more
frequent bowel
movements
● An enlarged
thyroid gland
(goiter), which
may appear as a
swelling at the
base of your neck
● Fatigue, muscle
weakness
● Difficulty sleeping
● Skin thinning
● Fine, brittle hair
5.2. Discuss the recent inventions that have improved the health and longevity of life.
Vaccines
● A vaccine is a biological preparation that provides active acquired immunity to a particular infectious
disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and
is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins.
● Vaccines mimic the virus or bacteria that causes disease and triggers the body’s creation of
antibodies. These antibodies will provide protection once a person is infected with the actual
disease-causing virus or bacteria. An immunization(vaccine) is a way to build your body’s natural
immunity to a disease before you get sick. This keeps you from getting and spreading the disease.
● Our body builds a defense system to fight foreign germs that could make you sick or hurt you. It’s
called your immune system.
● To build up your immune system, your body must be exposed to different germs. When your body is
exposed to a germ for the first time, it produces antibodies to fight it. But that takes time, and you
usually get sick before the antibodies have built up. But once you have antibodies, they stay in your
body.
● The next time you’re exposed to that germ, the antibodies will attack it, and you won’t get sick.
Importance
1. Vaccines help reduce the risk of certain illnesses by introducing dead or weakened versions of
disease-causing germs (bacteria or viruses) to the immune system which stimulate the production of
antibodies to provide immunity against one or several diseases.
2. Vaccines protect vulnerable people in our community – such as very young children, the elderly, or
those who are too sick to be immunized.
3. Some vaccines offer lifelong immunity.
4. Immunization greatly reduces the risk of catching a disease, which in turn reduces the risk of
complications.
A significant turning point in the way diseases are diagnosed, treated, or prevented has the potential to
extend and save lives. Medical advancements are also vital to society, progression in science reduces the
financial burden of disease and protects healthcare systems.
● There are many reasons why new drugs are important, such as new diseases, the development of
drug resistance, and our increasing understanding of health conditions allowing treatment of
previously untreatable conditions.
● Antibiotics are one of the most commonly used and well-known drugs for fighting bacterial and fungal
infections. Since 1990 only three new classes of antibiotics have been established, although many
derivatives of existing drugs have been developed.
● Advances in medical treatment have helped people avoid disability and death caused by disease,
lowered overall treatment costs, and has lowered death rates for heart disease, stroke, cancer, and
other deadly diseases for several decades. Innovation in drug discovery, biotechnology, digital health
and medical devices has the potential to provide new and improved treatments for some of the
leading causes of death such as heart disease, strokes and cancer. They also have the power to
eradicate diseases and prevent patients from developing conditions at all.
● The COVID-19 pandemic has highlighted the possibility of new diseases occurring. New drugs are
required to treat the symptoms of new diseases but also to prevent the spread of new diseases by
vaccination. The continued incidence of new diseases is likely to continue as humans interact more
and more with other species. Many new diseases, like SARS-CoV-2, originate in animals.
● There are many examples of recent diseases that have crossed from an animal host to humans.
Examples of virus transmission are HIV/AIDS, Ebola, flu, and even the common cold. In addition to
virus transmission, diseases can also be caused by bacterial or fungal infections or by animal-borne
parasites such as malaria.
● Outlined above are some reasons why new drugs are required. New drugs must be developed so that
we can continue our chosen lifestyles and prevent the misery and death caused by diseases.
Disease-causing vectors continue to evolve, throwing up new challenges and in general, humans are
living longer so they have more time to be exposed to diseases.
● To maintain our health, we need to be able to fight against well-known and increasing health
conditions, such as cardiovascular disease which kills seventeen million people a year, and new
diseases such as COVID-19 which can massively disrupt the world and kill millions of people in the
first year it occurs.
Timeline of improvement
Hans Berger recorded the first human electroencephalogram (EEG), charting electrical
activity of his son’s brain. He also invented the first electroencephalogram device.
The negative pressure ventilator, or iron lung, was a mechanical respirator. Although there
were prior prototypes, the Drinker respirator, which was first used in 1928 to treat a girl with
polio, went into production after her recovery. Negative pressure ventilation has been
replaced almost completely by positive pressure ventilation through an endotracheal or
tracheostomy tube. Sure, now it’s virtually obsolete, but during its heyday, the iron lung saved
lives. It’s also a good reminder that continued innovation is an integral part of MedTech.
The first minimally invasive surgery involved using a cystoscope to treat bladder lesions.
Other techniques followed, such as a balloon embolectomy catheter for removing blood clots.
Researchers had applied electrical impulses to stimulate the heart for a number of years, but
in 1932, Dr. Albert Hyman devised a spring-wound, hand-cranked electro-mechanical
instrument he called the “artificial pacemaker.” In 1958, the first patient received an
implantable pacemaker.
● 1943: Dialysis
Dr. Willem Johan Kolff is credited with the first working dialyzer. He constructed it during Nazi
occupation in the Netherlands, when resources were scarce, building it from beverage cans,
washing machine parts, and other available materials. Another important lesson here: when
there’s a will…
A 14-year-old boy’s heart stopped during surgery, and Dr. Claude Beck at the University
Hospital of Cleveland ordered his research unit that he had used to deliver AC to the
exposed hearts of animals be brought up to save him. The unit had two metal tablespoons
attached to wooden handles to deliver the shock. In 1965, Frank Pantridge installed the first
portable defibrillator — weighing 150 pounds and powered by car batteries — in an
ambulance in Belfast, Northern Ireland.
The Nobel Prize in Physics that year went to Felix Bloch and Edward Mills Purcell for
developing nuclear magnetic resonance. The first MRI exam on a patient took place in 1977,
beginning an era of non-invasive diagnosis.
Heart-lung bypass, supporting a patient’s heart and lung functions during open-heart surgery,
was invented by Dr. John Heysham Gibbon, and used successfully for the first time in 1953.
1953 also marked the first cochlear prosthesis, which stimulated the cochlear nerve to
facilitate hearing. Innovator André Djourno also performed the first cochlear implantation in
1957.
lthough Doppler ultrasound had been used in a variety of applications prior, in 1958, Dr.
A
Edward H. Hon of Yale used it to detect a fetal heartbeat. It has since become a standard in
prenatal care. (Sending results to bakeries for pink or blue icing inside cakes falls much later
on the timeline.)
Insulin pumps, which eliminate the need for multiple insulin injections each day and make
controlling blood glucose levels more possible, were invented by Dr. Arnold Kadish. In 1973,
Dean Kamen (also inventor of the Segway) invented the first wearable infusion pump.
● 1971: CT Scanner
Dr. Godfrey Hounsfield is credited with developing the first commercial CT scanner. The first
CT scan occurred in London, on a patient suspected of having a frontal lobe tumor. The
surgeon who operated on the patient remarked, “It looks exactly like the picture.”
● 1982: First Successful Implantation of an Artificial Heart
Dr. William DeVries implanted the Jarvik 7, named after the device’s inventor, Dr. Robert
Jarvik, giving Dr. Barney Clark the first permanent artificial heart. Today, artificial implants are
used as a bridge until a heart is secured for transplant.
his was the year science fiction seemed to meet healthcare when robots became part of
T
laparoscopic surgery procedures and lasers were used to correct vision.
A patient with muscular cancer received the “Edinburgh Modular Arm System,” the first bionic
limb. The patient wore a cap that contained micro-sensors which detected brain impulses
sent to his missing limb and used them to control the arm. Today, computer chips sync joints
to Bluetooth devices that coordinate movement.
Prosthetics had been around for years, but in 2004, the Ossur Corporation produced a
microprocessor controlled knee that adapts to terrain and permits activities such as cycling,
walk-to-run, and climbing stairs.
D printing technology has enabled researchers to print body parts, not just with synthetic
3
materials, but using bioprinting, growing cells from a patient’s stem cells to, for example, print
skin to encourage faster burn or wound healing.
Advancement of genetics and other biotechnology for the discovery of gene therapy, genetic
engineering, stem cell technology, hybridoma cell technology
● Taking time to learn about genetics can help you understand your own health and make healthy
choices. Genes that do not work correctly can cause problems. A group of rare diseases are caused
when a single gene stops working normally.
● Genetics research studies how individual genes or groups of genes are involved in health
and disease. Understanding genetic factors and genetic disorders is important in learning
more about promoting health and preventing disease.
● Gene therapy involves altering the genes inside your body's cells in an effort to treat or stop
disease. Genes contain your DNA — the code that controls much of your body's form and
function, from making you grow taller to regulating your body systems. Genes that don't work
properly can cause disease.Gene therapy replaces a faulty gene or adds a new gene in an
attempt to cure disease or improve your body's ability to fight disease. Gene therapy holds
promise for treating a wide range of diseases, such as cancer, cystic fibrosis, heart disease,
diabetes, hemophilia and AIDS.
● Stem cell therapy, also known as regenerative medicine, promotes the repair response of
diseased, dysfunctional or injured tissue using stem cells or their derivatives. It is the next
chapter in organ transplantation and uses cells instead of donor organs, which are limited in
supply. Studies have discovered that stem cell therapy can help enhance the growth of new
healthy skin tissue, enhance collagen production, stimulate hair development after incisions
or loss, and help substitute scar tissue with newly developed healthy tissue.
● Hybridoma technology is one of the most common methods used to produce monoclonal
antibodies. In this process, antibody-producing B lymphocytes are isolated from mice after
immunizing the mice with specific antigen and are fused with immortal myeloma cell lines to
form hybrid cells, called hybridoma cell lines. Hybridoma technology produces highly pure
and specific antibodies (monoclonal antibodies). This method is highly reproducible and
scalable. This method provides an unlimited production of monoclonal antibodies. It can be
used to perform highly sensitive and specific assays.
AREA 2: CHEMISTRY
1. Inorganic Chemistry (BARQUILLA)
1.1. Distinguish the three states of matter and the types of mixture
● The three states of matter are:
❖ Solid
➔ Highly Strong intermolecular forces between the molecules, leads to a definite
volume in Solids.
➔ Has a definite shape
➔ The intermolecular space between solids is absent.
➔ The force of attraction between the molecules is incredibly high.
❖ Liquid
➔ The intermolecular forces are stronger than gases but weaker than solids.
➔ Has no definite shape
➔ The intermolecular space is moderate but present.
➔ The force of attraction between molecules is moderate.
❖ Gas
➔ The intermolecular forces are practically non-existent. Thus, there is no definite
volume.
➔ Has no definite shape
➔ The intermolecular space is free-flowing and plenty.
➔ There is no intermolecular force of attraction between the molecules.
❖ Homogenous
➢ has a uniform composition and appearance
➢ Individual substances cannot be visually differentiated.
➢ Example: sugar in coffee, alcohol in water and milkshakes.
❖ Molecular Formula: gives the total number of atoms of each element in each molecule of a
substance.
Example: N2O4 = There are two nitrogen atoms and 4 oxygen atoms.
❖ Structural Formula: identify the location of chemical bonds between the atoms of a molecule.
Example: H-O-H or water (H2O)
● Chemical Notations:
➔ All atoms of a particular element have the same number of protons in their nucleus.
➔ Atomic number refers to the number of protons found in the nucleus in any given atom of an element.
➔ Atomic Mass= No. of Protons + No. of Neutrons
❖ Subscript
-are used to denote the exact number of atoms present.
-are always written to the bottom right of the element it is referring to.
-are used when more than one atom of an element is present. If no subscript is written, it is
assumed only one atom of that element is present.
Example: A molecule of methane has one atom of carbon and four atoms of hydrogen. The
chemical formula is = CH4
. (subscript "4" to the right of the H, indicating that there are four atoms of hydrogen in
this molecule.)
❖ Superscript
-appear on the top right of the symbol or formula.
-appear either as an "+" or "-" sign with an associated number. Together, these refer to the
number and kind of charge present on the ion.
-represents the mass number of the element.
➢ Hydroxyl group - a alkyl group bonded a single bond to oxygen and hydrogen bond
■ Alcohols - A class of organic compounds characterized by one or more hydroxyl
groups(-OH)
➢ Carboxyl group - a functional group that consists of hydroxyl group (OH) and carbonyl
group (=O).
■ Formic acid - is the simplest carboxylic acid containing a single carbon.
■ Acetic acid - is a byproduct of fermentation, and gives vinegar its characteristic odor.
Vinegar is about 4-6% acetic acid in water.
2.2. Describe the basic reactions of organic compounds
❖ Addition Reaction - is an organic reaction in which two or more molecules combine to
generate a bigger one. This reaction is common in alkene.
➢ Halogenation - a chemical reaction that involves the reaction of a compound with a
halogen and results in the halogen being added to the compound.
➢ Hydrogenation - The reaction of hydrogen and nitrogen to form ammonia and the
reaction of hydrogen and carbon monoxide to form methanol or hydrocarbons,
depending on the choice of catalyst.
3. Biochemistry (VILLANUEVA)
3.1. Show understanding of the structure, functions and reactions of macromolecules
❖ Carbohydrates - are large macromolecules made up of carbon (C), hydrogen (H), and oxygen (O)
with the general formula Cx(H2O)y. The primary function of carbohydrates is that they are the primary
source of energy and preferred energy of the brain.
➢ Types of Carbohydrates
■ Monosaccharides - The simplest forms of sugar and the most basic units (monomers)
from which all carbohydrates are built are known as simple sugars. They are typically
colorless, crystalline solids that are water soluble. ( fructose ”fruit sugar”, galactose
and glucose)
■ Polysaccharides - are the most prevalent carbohydrates in food. They are polymeric
long-chain carbohydrates made up of monosaccharide units linked together by
glycosidic linkages. (cellulose, starch, and glycogen)
❖ Lipids - a substance that is insoluble in water and soluble in alcohol, ether, and chloroform. Lipids are
an important component of living cells. The structure of lipids is typically made of a glycerol backbone,
2 fatty acid tails (hydrophobic), and a phosphate group (hydrophilic).
➢ Unsaturated - Unsaturated fatty acid is indicated when a fatty acid has more than one double
bond. “Often, naturally occurring fatty acids possess an even number of carbon atoms and are
unbranched.” On the other hand, unsaturated fatty acids contain a cis-double bond(s) which
create a structural kink that disables them to group their molecules in straight rod-like shape.
➢ Saturated - Lack of carbon-carbon double bonds indicate that the fatty acid is saturated. The
saturated fatty acids have higher melting points compared to unsaturated acids of the
corresponding size due to their ability to pack their molecules together thus leading to a
straight rod-like shape.
❖ Proteins - Protein is an essential component of a healthy diet. Proteins are composed of chemical
'building blocks' known as amino acids. Amino acids are used by the body to build and repair muscles
and bones, as well as to produce hormones and enzymes. They can also be used as a source of
energy.
❖ Nucleic acid - are large biomolecules that are required by all cells and viruses. Nucleic acids play an
important role in the storage and expression of genomic information. DNA, or deoxyribonucleic acid,
encodes the information that cells require to produce proteins.
➢ Types of Nucleic Acid
■ Deoxyribonucleic acid (DNA) - An
organic chemical that contains
genetic information as well as
protein synthesis instructions. It can
be found in the majority of cells in all
organisms. DNA is an important
component of reproduction in which
genetic heredity is passed down from
parent to offspring.
■ Ribonucleic acid (RNA) - a
nucleic acid found in all living cells that
resembles DNA in structure. RNA, unlike
DNA, is typically single-stranded.
Instead of the deoxyribose found in
DNA, the backbone of an RNA
molecule is made of alternating
phosphate groups and the sugar
ribose.
● mRNA - serves as
intermediary between DNA and protein; used by ribosomes to direct synthesis
of protein it encodes.
● rRNA - Ensures the proper alignment of mRNA, tRNA, and ribosome during
protein synthesis; catalyzes peptide bond formation between amino acids
● tRNA - Carries the correct amino acid to the site of protein synthesis in the
ribosome
3.2 Discuss how bacteria, viruses and chemicals affect human health
❖ Bacteria - can cause a variety of diseases in humans, including cholera, diphtheria, dysentery,
bubonic plague, pneumonia, tuberculosis (TB), typhoid, and many others. When the human body is
exposed to bacteria that it does not recognize as beneficial, the immune system attacks them. While
the bacteria which help in human health are called probiotics like Lactobacillus acidophilus or
L.acidophilus which help digestion food. Some bacteria are being used to produce some chemical
that is beneficial to the health like E.coli to produce Insulin through Gene editing (CRISPR).
❖ Viruses - Some viruses that infect humans can cause severe and often fatal diseases, but other
viruses can be manipulated to be beneficial to human health. These viruses hold the promise of
curing cancer, correcting genetic disorders, and combating pathogenic viral infections. An example of
a good virus that is beneficial to humans is the latent (non-symptomatic) herpes viruses that can
help human natural killer cells (a specific type of white blood cell) identify cancer cells and cells
infected by other pathogenic viruses.
❖ Chemicals - the common misconception that all chemicals can be hazardous or toxic since some
Chemicals can be toxic because they can harm us when they enter or contact the body and some are
volatile. But some of the chemicals that we are using are very beneficial to human health it being
used for sanitation, hygiene, sterilization, disinfectants, antiseptics, in pharmaceutical manufacturing
of medicines for example the amides that being used to make “paracetamol”, etc. to improve human
health.
C. PHYSICS
1.2. Illustrate the transfer of energy from one place to another and from one form to another (VILLAGORDA)
Energy can be transferred from one place to another and from one form to another;
● Energy Transfers
- Energy can be transferred from one place to another
Example:
1. Think of the electricity that flows from your wall socket, then moves through a
charger and into a battery. The energy is being transferred from the wall socket
to the battery.
2. Heat energy is transferred from the element in stove to the pot when you are
cooking
3. When you kick a soccer ball down the field with your moving leg (transferring
energy from your leg to the ball)
● Energy Transformations
- Energy can be transformed from one form to another, which makes things in our world
happen. When something or somebody moves or jumps or falls or explodes or
breathes or thinks or dances or does anything, it's because energy is being
transformed.
Example:
1. Chemicals in food give us mechanical energy
2. The sunlight provides light energy for the tree to make its own food (chemical)
4. The electrical energy plug creates the heat to run the stove
Resources:
https://www.google.com/amp/s/slideplayer.com/amp/9369460/
https://www.solarschools.net/knowledge-bank/energy/conversion
https://mskuksclass.weebly.com/lesson-3-energy-transformations.html
1.3. Discuss the uses of electromagnetism for motors, generators, transformers, x – ray, etc.
(PAGULONG). Add Ohm’s Law (Resistance, Current, and Voltage)
Devices Function
Hard disk drive A hard disk drive (HDD), hard disk, hard drive, or fixed disk is
an electro-mechanical data storage device that stores and
retrieves digital data using magnetic storage and one or more
rigid rapidly rotating platters coated with magnetic material.
The platters are paired with magnetic heads, usually arranged
on a moving actuator arm, which read and write data to the
platter surfaces. Data is accessed in a random-access
manner, meaning that individual blocks of data can be stored
and retrieved in any order. HDDs are a type of non-volatile
storage, retaining stored data even when powered off.
Modern HDDs are typically in the form of a small rectangular
box.
Current, voltage, and resistance is called Ohm’s Law, discovered by Georg Simon Ohm and published in his
1827 paper, The Galvanic Circuit Investigated Mathematically.
To be able to make meaningful statements about these quantities in circuits, we need to be able to describe
their quantities in the same way that we might quantify mass, temperature, volume, length, or any other kind
of physical quantity. For mass, we might use the units of “kilogram” or “gram.”
For temperature, we might use degrees Fahrenheit or degrees Celsius. Here are the standard units of
measurement for electrical current, voltage, and resistance:
Ohm’s principal discovery was that the amount of electric current through a metal conductor in a circuit is
directly proportional to the voltage impressed across it, for any given temperature. Ohm expressed his
discovery in the form of a simple equation, describing how voltage, current, and resistance interrelate:
In this algebraic expression, voltage (E) is equal to current (I) multiplied by resistance (R). Using algebra
techniques, we can manipulate this equation into two variations, solving for I and R, respectively:
1.4. Distinguish the characteristics and functions of waves and optics (VILLAGORDA)
● Crest is the highest part of a wave
● Wavelength is the distance two crests or two troughs
● Amplitude is the wave's height from the origin to a crest or to a trough
● Trough is the lowest part of a wave
● Frequency is the number of waves that pass a given point in one second
Resources:
https://www.pinterest.ph/pin/721561171523288874/
https://www.blendspace.com/lessons/MrPGJK2PUhiY4A/characteristics-of-waves
Plank’s Theory
1. Different atoms and molecules can emit or absorb energy in discrete quantities only. The smallest
amount of energy that can be emitted or absorbed in the form of electromagnetic radiation is known
as quantum.
2. The energy of the radiation absorbed or emitted is directly proportional to the frequency of the
radiation.
3. It is named after Max Plank.
Formula: E = h ν
Where,
E = Energy of the radiation
h = Planck’s constant (6.626×10–34 J.s)
ν= Frequency of radiation
Modern Physics- it deals with the post newtonian concepts. It involves an advanced description of nature
through new theories which were different from the classical descriptions and involves elements of quantum
mechanics and Einsteinian relativity. For instance, quantum effects typically involve distances related to
atoms. On the other hand, relativistic effects typically involve velocities compared to the speed of light.
D. EARTH SCIENCE
1. Meteorology and Astronomy (ABES)
1.1. Explain the interconnections of land, ocean and atmosphere to human life on Earth
● The components of the system: the land, ocean, atmosphere and humans are inextricably
intertwined. Without the atmosphere , earth’s surface would be frozen and life would not not be
possible. Atmosphere does not only contain the oxygen we need to live but it also protects us from
ultraviolet solar radiation and keeps temperature habitable for our living earth. The oceans are the
atmosphere’s partner in the physical climate system.Oceans help in creating rains and typhoons by
evaporation of ocean to atmosphere. However, land provides vital socioeconomic resources to
humans.
1.2. Illustrate the cycles of water, carbon, rock and other materials that sustain the inhabitants of
planet Earth
The water cycle describes how water evaporates from the atmosphere, cools and condenses into
rain and falls again to the surface as precipitation.
The rock cycle is the process in which rocks are continuously transformed between the three rock
types: igneous, sedimentary and metamorphic .
The carbon cycle is nature's way of reusing the carbon atoms which travel from the atmosphere into
organisms in the earth and then back into the atmosphere.
1.3. Demonstrate the characteristics of non – Earth bodies and phenomena such as the sun, moon,
stars, planets, etc.
-Stars can be defined by five basic characteristics : brightness,color, surface temperature,size and
mass.
-The moon is Earth’s only natural satellite. It is a spherical rocky body, probably with a small metallic
core.
- Just like the other stars, the sun is made up mostly of hydrogen and helium.
1.4. Describe the benefits derived from space exploration
- Space exploration thus supports innovation and economic prosperity by stimulating advances in
science and technology.
Individuals live together in populations. Different populations together make up a community. Communities
together with the non-living things in their surroundings make up an ecosystem. All the ecosystems on Earth
make up the biosphere.
2.2. Deliberate the food chain links which show how the organisms are related in utilizing energy and
nutrient
● A food chain shows how energy is transferred from one living organism to another via food. It
is important for us to understand how the food chain works so that we know what are the important
living organisms that make up the food chain and how the ecology is balanced.
● Photosynthesis is only the beginning of the food chain. There are many types of animals that will
eat the products of the photosynthesis process. Examples are deer eating shrub leaves, rabbits
eating carrots, or worms eating grass. When these animals eat these plant products, food energy
and organic compounds are transferred from the plants to the animals.
● A food chain describes how energy and nutrients move through an ecosystem. At the basic
level there are plants that produce the energy, then it moves up to higher-level organisms like
herbivores. After that when carnivores eat the herbivores, energy is transferred from one to the
other.
● In the food chain, energy is transferred from one living organism through another in the form
of food. There are primary producers, primary consumers, secondary consumers and
decomposers- all part of the food chain.
E. SCIENCE INSTRUCTION
● Teamwork skills
- Cooperative learning
- Forming teams
- Cooperative learning structures
- Turning groups into high-performance teams
- Dealing difficulties
Reference: Corpuz, Brenda B. LET Comprehensive Reviewer Based on the NCBTS and Table of Specifications (TOS): Specialization Biological
Science. Lorimar Publishing Incorporated, 2018.
2. Research (GUEVARA)
2.1. Manifest familiarity with the basic investigative research in science
● Scientific investigation
○ Asking a Question
○ Forming a Hypothesis
○ Testing the Hypothesis
○ Drawing Conclusions
○ Communicating Results
● Steps of the Scientific Method
1) Describe what it means to "Ask a Question."
2) Describe what it means to "Construct a Hypothesis."
3) How does a scientist conduct a fair test?
4) What does a scientist do if the hypothesis is not supported?
● General format of a research paper
○ Chapter 1: Problem & its background
■ Introduction
■ Conceptual and/or theoretical framework
■ Statement of the problems
■ Research hypothesis
■ Significance of the study
■ Scope and delimitation
■ Definition of Terms
○ Chapter 2: Review of related literature and studies
■ Related Literature (Local and Foreign)
■ Related Studies (Local and Foreign)
○ Chapter 3: Methodology
■ Research design
■ Material development
■ Research locale and participants
■ Research instruments
■ Research procedure and ethics
■ Statistical tools and data analysis
○ Chapter 4: Results and discussion
○ Chapter 5: Summary, conclusion and recommendation
■ Summary of the study
■ Summary of findings
■ Conclusions
■ Recommendations
Resources:
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Book%3A_Introductory_Biology_(CK-12)/01%3A_Introduction_to_Biology/1.
01%3A_Scientific_Investigation
[Lawsin, N. (2021). Research Writing: Designs, Tools, Analysis, and Reports. Pamantasan ng Lungsod ng Muntinlupa]
2.2 Demonstrate proficiency in interpreting graphical presentations of data and conclusions drawn
from inferential analysis of results
● Inferential Analysis - Collects data from a sample and draws conclusions about the population and
from the sample
● Types of inferential analysis tests
Chi-square test (x2 test): used to identify Questions that the chi-square test could
the difference between groups when all of answer might be:
the variables are nominal (also known as, a ● Are education level and marital
variable with values that don’t have a status related for all people in the
numerical value), like gender, salary gap, United States?
political affiliation, and so on. ● Is there a relationship between voter
intent and political party
membership?
● Does gender affect which holiday
people favor?
Data Analysis
1. Descriptive Statistics = “to describe the sample or population”
❖ Common Questions, “What is the level…?”, “How can the sample be described in terms of
their academic performance?”
❖ Frequency, percentages, mean (scores are normally distributed), median (scores are
skewed).’
❖ It can be presented through graphs to see the trends of data.
➢ Skewed Distribution
■ Interval-Ratio = Kruskall-Wallis (2 groups); Welch F-test (3 or more)
❖ Significant relationship:
➢ By pair of variables (A vs B) or if you have 3 variables (A vs B), (B vs C), and (A vs C)
➢ Nominal = chi-square test of independence; Ordinal = Spearman Rank Order
Correlation Coefficient or Spearman rho; Interval-Ratio = Pearson Product Moment
Correlation Coefficient or Pearson R.
REFERENCES
● R.A. 7836: Philippine Teachers Professionalization Act, s. 1994, Sec. 14. Scope of Examination: The examination for the elementary and
secondary school teachers shall be separate. The examination in the elementary level shall consist of two (2) parts, namely: professional
education and general education. The examination for teachers in the secondary level shall consist of three (3) parts, namely: professional
education, general education, and field of specialization CHED Memorandum OrderNo. 75, s. 2017: Policies, Standards and Guidelines for
Bachelor of Secondary Education (BSEd)
● DepEd Order No. 42, s. 2017: National Adoption and Implementation of the Philippine Professional Standards for Teachers (PPST) by
integrating the 7 Domains of Quality Teaching
● R.A. 10968: The Philippine Qualifications Framework (PQF) Act of 2018