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CC Automation

The document discusses early automation technologies used in clinical laboratories including centrifugal analyzers and dry slide technology. Centrifugal analyzers, developed in the late 1950s, use timing of reactions and centrifugal force to mix samples and reagents and allow multiple analyses to be performed. Dry slide technology uses multilayer chemical-coated slides where sample is applied, spreads, and reacts to produce color changes indicating results. Both technologies helped facilitate processing more samples in less time and with improved reproducibility compared to earlier manual methods.

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Jilycamae COSMOD
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© © All Rights Reserved
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Download as PDF, TXT or read online on Scribd
2 views

CC Automation

The document discusses early automation technologies used in clinical laboratories including centrifugal analyzers and dry slide technology. Centrifugal analyzers, developed in the late 1950s, use timing of reactions and centrifugal force to mix samples and reagents and allow multiple analyses to be performed. Dry slide technology uses multilayer chemical-coated slides where sample is applied, spreads, and reacts to produce color changes indicating results. Both technologies helped facilitate processing more samples in less time and with improved reproducibility compared to earlier manual methods.

Uploaded by

Jilycamae COSMOD
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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*

_1. use of barcodes A. ROBOTICS


_2. response time decreases B. COMPUTERS
_3.responsible for data handling C. SENSORS
_4.allow warnings of equipment malfunction
B
_5. to facilitate a less crude way of specimen
processing

B
_6.elevated results can be monitored
_7. QCs can also be monitored
L
_8. more samples processed at shorter time
_9.can also be built on microchip
C

EARLY AUTOMATIONS

A
_1.the use of air bubbles in sample & reagent A. CFA: SEGMENTED STREAM
stream B. CFA: FLOW INJECTION
B_2.valuable in enzyme level studies. C. CENTRIFUGAL ANALYSIS
_3.developed in late 1950s by Leonord Skeggs D. REAGENT PACKAGE

· _4.provides a high degree of reproducibility


_5.direct injection of sample was utilized
_6.permits test selectivity
TECHNOLOGY: DUPONT aca
E. DRY SLIDE TECHNOLOGY:
EASTMAN KODAK

i _7.developed in mid 1960s


_8.it is very slow, under 200 tests per hr

B
_9.timing of reactions
_10. centrifugal analyzers
_11.removal of air bubbles
_12.chemical and samples travel through the
instrument.

B
_13.multiple analysis is achieved
_14.contains all reagant necessary to a single
analysis
D_15.stationary flow through system

MAJOR PARTS OF ROTOR


n
_1.outer edge of rotor A. INNER CHAMBER
_2. sample compartment. B. REAGENT CHAMBER
_3. Specimens: serum, plasma, CSF, and urine. C. OUTER EDGES OF CHAMBER
_4.serves as cuvette for analysis D. ROTOR SPIN
_5.the use of very small volumes of the sample
_6.two chambers are separated by a plastic wall
L
_7.area where the light pass through the solution
_8.under pre-determined manner
_9.allow mixing and light readings to be made.

COMPONENTS OF DRY SLIDE

#_1.asa i drop ang sample from the machine


_2.contains all the chemicals necessary for the
A.SPREADING LAYER
B. REAGENT LAYER
specific reaction C. INDICATOR LAYER

&_3.Located at the bottom


_4.another optional layer (not present in all
D. SUPPORT LAYER

slides)

B_5. where the entire slides is constructed


_6. Point of contact of the sample
A_7.act as sieve and will not allow large
molecules as proteins to pass
B_8.transparent when the colored complex is
measured.

↑_9.range of 10microliter or less


_10.contains dye or some type of indicator

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