aio, Le compounds Lo obtained axe at NGL BY anor 7 ; Ho pe : So containing anic clue %) CMLOUNL antibl ae — dnalogr ' = K Synthetic dalogen Girmpound > Cees A am anastnette daring audigy 4 CLASSIFICATION OF HALOGEN CONTAINING ae "COMPOUND —— : i On the basis of Compound conti Conpousad wo. of dnaloger — [sp))C—X Bond _,,jrmacnaney (SPE = % Mg (2) Drhal (2) Atle. nal den Q) bugle Anodic e1treN ATOMS 8 se a Oe J ON THE BASIC OF NUMBER. OF HALO monshaloge Compounds? [1- Halogen ator] Boo gp 3 a-H,-Be > CS ce 2:7 &,-tt, > ee tee et ; ore = a el) @ Cte Cl te B)Tuihallogen Compounds 1 [ 3- Hologen ator] Bm owe, f gum” (6) Polyhalogen. Conrpouncls? [>3- Halogen atom] Bie CCl, ( Carbon Tetiichieuidaumenal B1 COMPOUND CONTAINING ¢—% BOND} 9) ALKYL HALIDES [ cm ob (spt ;(2) AULYLICc HALIDES [ ep eee xX] 2 bn Miyptit raises , duoboger. wounected 10 @ caxbon utnat UU (sp?) riclerd amd tab cotban i comnected ‘40 a carbon thneis 5p* hybidlecd: 2 thu We vompounols inwtich a bonded. 0 om zp'-baybucieed CONIaae oddone adyouent sto carbon-carbon double bond (C=C) 3 8s csp’) espe 9) eee ee (SP | Usp? (©) BENZYLIC HALIDES | Cages arcmin goad vowed im wtih tie ata 4ato. 4 0. carbon-carbon clouble bond (6 C) - [ving Brom] csp) ¢x) ) (@) ARYL HALIDES . Bs corpouncl Or | mushich Ue hy ator vs dimect: bonded to a spt ' Stirs. cape cera) axcrnae tg Hi 2 ( é H IUPAC Nomunch, =, me [Peeper e + Prepinc # Word koot + Sub = “ate Ea ae 2 \ a p ie = o pe | s Bes Bromo i ‘ t L a { Bemocthany ‘OL, ; chs cH - Ces | se ¢ ) ERC), Gt Bra > | - Beam - zi 2 . tris os Uf beau 1 ie (c) FROM (©) HALOGEN meonors HYDROCARBONS on " EXCHANGE C OCARR % Bh ancl rth, Ww exon. alkanes 0) Ptnblesteun (® From alkenes (D) SANDMEVER'S ~ Reaction ping nase "[t) Addition of HX REACTION — (gy Sunt Ir) Addition a Xz Reach °) al et a HyPO wy Fon 4 W) using PCs Base G — = & wing Pll, [Al P i © Ww Solty f Using Hated He & ana d0Ud . ® a) Red PL wing Red Pe : : 1 > MiaduKe > conc .HCe k awh. cull, 44 CARE LUCAC REAGENT ; 2 Anh. > ROR + HOU mney sai (Alcohol) Cumnc.) CHatoate Gb > Utg-U,-On +ye ER D4 3'p aot" ecause yee Peet? Ber Hey | 2) ny NABH + Hy SOn a a OH + NOBK+ HO, ——> R-AK + HO + NaHsoy E 4 CMs -CHR0H + NAB + Hy80q ———* (1 CHy- By +H, 0 + NAH Soy Ethanol Buomottiant Bug KI + HPO, c EP HPO) + @-T + 1504 Kish, E Cg-0H + KI + N3 P04, > CHg3-L+H,0 + KH,POy Methanol dodomelrane La on 4 sa yf whe cotol with 222 sa i) found Ha 1, 2 bs ag A iy diz et, by i ieee Hence wt cbnmot Ut HpSOy Pts Pisani Talcktoride 1 SR-0H +PCt, ——> 3H tH;P0,“ee stots - Ud, Uy OH + PC —> hy Hy Ce +H ce +f ee ropa - 1 - of ee us Sote, [ [thionyl chbonide Tfonezent's METRE. 'g wenoo Pi [industrial use J =) f-0H +Socf, —* ket + nels + $0,7 5 0,4 iB (ly CHy OH +5000 —F Ug tH, - + Hert +508 El Ne? Plly/PRtsvPI,/ qermpounds He PLLg /PbusKP Ze X f apnistieg ng ted Poud tu, 7 0H TOPS E Red P+ Ta (8) lig hud Pamd I, 7h-04 (8) Puipaxation palpi (1) From Alkane [by Foe ad Hobope beratiOon T a fr tad elo. uondaion Alkan Ines ov a Lee 9. some ie =k RB > R-L eae hv CHsCls + HCE Mellen tohonTenachlonisle » Fire Ext tinguishers 5 (Hy- (Hz =e (He- Het + Hee Ethane \ = Ue - ct Ps, PT Chg teas Ck py tHts Propene 1 -chlowoprepane | (MINOR) ot d-Unborwpopant (MAJOR) — a Wane Q-Monoohloninatecl products - Utg- Ul, ~ (Hy CH i 2 Mono- chlorinated ducts outa ses ote 7 Ag a |(oH Pek hy., 2 4 products Bree a a ? L products ae ae Up =H a ‘5 momochlotiae=> Ut) = (H- CH, + H-Re —_, us te , | (Propox) a [a - BHemopaopane | Aunrding do Harkowni Koy's Lubes a > Negative Pa seawent will attack '¢ * ator “HY okome . Epmsainling bets = Ch, = CH- (Hy + Bu- yeaa 02a thy — (troeide) “| ~ He OH 7 bun bx ; old (1- Bromopuopanc] to Makourn Kone Rule : TM, agin wil ete ata APPLIC (ABLE. OnLy oe Heb.[eto 5 yy — crs | | ee ee [ 1, 2 - Dichlorocthane J CVISCINAL] Btn Ee h =(H- CH, + Bay pace (Ha - CH - Hs ee ; Be by | 1, 2—Dibaomopropant ] « : | (9) Preparation of Haboarcnes pron Aromatic bngdltoceabonts bask, Anh : fees 1 Substitution ow axomatio part ) ot Ih. AlCl, i Bx +B AES Anh-FeBh, + HBK buemohimeme .Notes Apove reactions ane knousy a4 i. Heres i puostitutey of wnyp22 2 © > ElectHophile 4 ‘nd, cL electseopprte EE Nic = nusleophile ©? ELECTROPHILIC CUBSTITUTION ( CLEA Baia REACTION , NALS Os OtHs aa roo : —/ l qouert fAnsole fy * [D] Prepanation of Haloaxents samdmeyer'e Reaction NH2 e (from Anitene) piaxotixation. oh = a Nanb2_+ 2H : a T5C CusCea + HCe aniline = _ pale = aH,0 Benzene diazonium Cnt + HOt + Condmeyer eget Reag ent Cuz Bie tH ba = tam, : ~ Samdnneyer'y : + HON er heapedEIN REACTION oe dhe toe > Oe-th,- Bx + NAT M4 > CH-o-7 ¢pang Buomoetrame HPO Togomethane ay Arete proven Horwuiny of tly NOE MOM. coluble “+ Day acetene U Uued . NOR SHH. drcoluble sf perry: “% pitt avetowe, Bolus. (2) swaetz REACTION > Leachon ts lt —— e-r + [aga] (K8 tt, 8x) : ffi 9 Chy-Ct + Agr ——> H-F & hat Fluxomethane aA] [ge Fa] |Cors | [SbF ] > Swartz Reagents . x H OPTICAL ACTIVITY iid . ttbnia) Light: mae5 ° clockwise dinection Optically tmactwe © = positive : - optically ative © Dextho substance . taeve ¢ubitance o d Ob) Loo 4 Assymethic 'c’ Atom gh cine 'c? Atom Bon. aterm whore att fi valencies ane aatigied J ey He 2 calted i ae Fae CHO ; fl [ H —C*%—on ” So ch Be stones whieh coset inal xine Of ¢ ato Aiea Ho Ho g H—t*—0n 5 #444 ale d ott) » ud (-) ENANTIOMERS —_ praise(HOH © gonna ‘orom * 4 Chinal’c’ atom ; ; opti Uy ative » aptrcally anne * dextho substance ee eae Re 52.5 o 8 = a8, t RACEMIC MIXTURE ance amd 90% a4 its Laevy 5 Migdure of 0% dentwo use ubseunce v4 called HOCENUL WhILAHE - ¢ Minune of 50% d- et Big & Ae wy Oe oe ls" efacemic WUAAUNE di apically ee) due to enteral cannpunsation. FE CHEMICAL PROPERTIES OF HALDALKA NES #€ ca ye ras Vv, ———— (b) B- Elimination (c) Reaction Mekolsah +kow e (4) : 3 ats TS tts Chy-C— bk + kon a uM aR ck (ay) R-Beome-2 A= mettulascopame =p m-a-ol Tectany - butHlhsornide i Toiany - butytateohol SE eee atten —— Btomomettane Ket + (H,-0H metramnot + KB Ethane nitatle 2 CHy-tH,— Be + BAUM armen Clg = a, i oO iE + Me : Bromoetnane Etuplic — thy neyndies be Became Ki aw be ust ha bd a woble vaony metal moto FC! hy wan sight = In as tae Aah a 4 atta dnint attachmunt. a ruscleophiles usrich ushich poseses more war. ene Te We te dime founda donde tthe gM OMe wmucleopnilic topilic centne 0 aeAq -0-N=0 KON ————> (N.__ KNO, ———> ONO AgiN———* No Agno, ———+ NOs FEMELHANISM OF NUACLEOPHILIC SUBSTITUTION REACTION # —a Se OH" ts 0 on (Htag ont) | (by: pee ; (at) (podunk) CH: Os 3 (Hz —C -----B% J__» c® + Bu OBS be FLA E ei a ais aes Son oa Bc Net: * FSA Front vide Mock BSA 7 hace vide Nav Os ote C a Se [ txamaition State- 1] one, Cewpsutabenlule will be front ae tae the il be 9% etn j & 50% 9 truer of cempg wralian . WJ substnate ut optically active , then product wu be eprically martome due to Lcvrnol ) Canipunsctio jim Nocennke wmistire LRavimisation ) # SN? Substitution Nucleophilic Bimoleculor ] Reackion ° 4 4 | | Hea c-(t + On og eee + CteA) Ondo 4 SuaLtivity of ubseHale 1°52°)3° B)Atiavke 54 awcleophile will, torlly be prom backuite- HUALE , 100" thnuienr Of WOMfiguitien - 6) 44 subsrnate — optt achive aoe 3g Produc — sah ouctdne , jua the compignation A | awed x¥d—ot x Lod TO] B- tommatter, ,pemylrohalogenation | aoe Reagent! » Me. KOH * KDR + Altohol » Kon + Ethanol * oH + CaHs0H e CrHg8 ‘ * potaasiunn vthoride possible names tn qucetion : oondad th 0 © Sadium athaide . 4 mo $ A 04 COnbOr ay ge Wi 2 Bu - O At + ? OG Jed, wie ey {eller ¢ Hs - A ee CH, = Uy elle © Ju b- Ca ae ae theme . ~ HOChlonepropane waa Juugpens 2- Arornobusaine sence wit KOH aie cil : H tthawal 2 me of Me. koH GH | UR,~ (Hs aco eH =O 1 AH [MOR] (Bis, [But - 1-wme) = g- vlimiuation CH, -CH = CH UL (MA]IL] : : > Souptzed{"t product —— : [ but - R- ene ) | 4 —F Suupteety's Rule 6 Laitior's dude t eat teaction alkune ushich A ee a ee Mability of Hatoatkaut alto depot on agp oconjugation ee OOH _, Mate oxnple a-H 3 = a a CH,> CH —tHz- Uz k pHs—CH= ty ce | L 2K-H Lise an °° More Stable > txplain why OGULOUd KOH fosrouse alveholic Kou pei Uimination 94eqs PU» Cy,-(Hy t ANUBK SB tHe Be +gnat OAs iy os u | Ebhane J [ouomonnethan ] bi via 16 eltoweds tm wenck wth. soda (Hy-CHy-h + Annee + CHeeHyc) —PM_s yoy, —un-Ghy +anace Le [Butane] Be cg cit 00s oh ake, Peele (CHe-CL + ANA + CO- cH, - yy 6 - edi seve, (oes + ANace * te :[ cretunanD a Ally L Magnesite Hauide A Uy Be + M ernie tH, MqB% de] ae pea ei scwicou. | tnopatiy 4 yuigpene BP imax + er 6 H+ MAOH) ay oi Eye @ Sty, yuget + HH —> oy * mg (et vd ¥ Methane. | -FE(HEMICAL PROPERTIES OF HALOARENES # Siege WW anopnit (tear th # weophilc Subsicution t eae Z “nn peactian (2) EESnANCe (1) HALDUENATION (s) wuerz- FITC @) DIFFRENCE OF (2) NITRATION REACTION HYBRIDISATION () swPHoNATION @) ecTTltr REACT 3) el (H) FRIEDEL CRAFT'¢ REPULSION FACED BY ALKYLATION INCOMING NucLeoPHie (5) FRIEDEL crrer's ACYLATIONone dikjvund Od vammpasied. td haloanents 2) +e 1 RESONANCE wtolivned bute casivon wan nabogive peaking of c-% poral becomes di 2 H2 DIFFERENCE OF HYGRIDIZATION (spe) 87 -$) tay-4% (Haloalkane) — (Raloayurt) a | % More > of S-nanacter » more will be ectnanegativily : | A dn nalocrus , ‘0's pt apprised ama Dente Ue wa atin . Luxor, bono butt CF Bi mun At : : hme gl: Ming Bsmt HE % UNSTABLE PHENYL CARBOCATION Be espe) C 38-33 %e-$) Bk A ®e 6 or + BA, OA pct [ Unstable Structure ] LegePS Ynough wider vigorous onlition Alas eaction 0 ‘ mM made pow ce ONA oH | a NaOH Q seauaniR is q 623 K (Avidigicasion) | [cnterobenauet] 300 ba — [sodtammmpnenoride ] LPacnol] Note Above process UU known oA p ct by on 2 wes Husk 4 eat : ? NO, = x added to NO, iy. uw ie ie plily the ud vonditiond 3 No, UW) NADH 5 er ae eB ¥ NO, & good electron Nop ae wt tulrawing qroup No 0 OH Ms nnn te, Ws ¢ - Nts pee Nov [2,4 6 -Trinitne phenol [ Paiouie Aud Jnitive & plo dinecting gvoups Hoy, Mabe etes, 1,2- didalorebmrne — mM an dethon donating group . 1, - oictlorobee 0 Mas De pL Cr 3 Nithabing mite is a Combination Af concemtxated HNO, t “onsentHated HpCOn Ca b ee con. HeS0u_, % N NO: es HNO Weer re d q : no Conc.) t ze) 1-Chlore-2-nitrobenzax ee 1-Chlono-4- nitvobencene, | (8202 [Oleum] 3 ee” 4 H,$04 & S05 tt'5- FRIEDEL CRAFT'S ACYLATION tt , 9 a Ct -k re OM) OOxR a ature 2 © + eee ct ey at (He + a erb insu A-tbo OWcekO folLno on & (Hs (C0) REACTION WITH METALS 4- Udooacetophtuaay “44F. WURTZ ~ PITTI REACTION (Hy 3 Hy -Ut Banh 7 tt-—<75) Duy Een j Toluene + 2NaCE. TT REALTION F ANat CLO) ae oOrz) Ao carbon akows Z yb, ; a. ieee UMEHEMLLS vols ouuuawoal’ : 8 four of ee a “ ee 3 CH,-CH- : i OH,- CH, BKO. 0 ) tt ae alo i haboatieeme wilh be very Lee in WAL “bus ane ead, soluble Lm MEM Ole soluimts Lily Elly [PDT Dichboww diphungt tnichlovometiane | | ORGANIC ce = |_ ENSECTICIDE H H i HOW. ay ae ct H H A