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Contrast enhanced mammography (CEM) involves injecting an iodinated contrast medium intravenously before a mammogram to better visualize breast lesions. Early experiments with CEM date back to the 1930s and 1940s. In the 1970s, CT studies showed contrast enhancement of breast cancers, and in the 1980s dual-energy subtraction was developed to improve contrast visibility. The first clinical experience with CEM was published in 2003. A 2011 study demonstrated CEM could identify breast lesions better than mammography alone. The FDA approved CEM in 2011.

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35 views2 pages

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Contrast enhanced mammography (CEM) involves injecting an iodinated contrast medium intravenously before a mammogram to better visualize breast lesions. Early experiments with CEM date back to the 1930s and 1940s. In the 1970s, CT studies showed contrast enhancement of breast cancers, and in the 1980s dual-energy subtraction was developed to improve contrast visibility. The first clinical experience with CEM was published in 2003. A 2011 study demonstrated CEM could identify breast lesions better than mammography alone. The FDA approved CEM in 2011.

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MAMMO ( CONTRAST ENHANCED MAMMOGRAPHY (CEM)

Study online at https://quizlet.com/_egdp0f

1. 1930s and 1940s; , Emil Ries investigated contrast-enhanced mammogra-


and Nymphus Frederick Hick- phy to obtain better visualization of the mam-
en (1900-1998) mary ducts

2. 1970s when preliminary studies showed that in-


travenously injected iodinated medium con-
trast was associated with an enhancement of
breast cancer lesions on computed tomogra-
phy (CT)

3. 1980s; William Brody and col- the concept of dual-energy subtraction (a


leagues concept based on time subtraction to im-
prove contrast visibility) was first developed
_______

4. Jong et al. in 2003 the first published article on the clinical ex-
perience of using CEM was published by
______ ; —for the first time, this study
demonstrated the good ability of contrast
applied to mammography to identify breast
lesions

5. 2011 by Dromain et al. ; The first paper that used this specific mam-
mograph was published in ; The performance
of CEM in identifying breast lesions was sig-
nificantly better than mammography alone

6. 2011 CEM received approval from the Food and


Drug Administration in the same year.

7. 1913; ALBERT SOLOMON First mammogram

8. 1965; charles gros First Xray- Device Exclusively for the breast

9. 1970 ; Shapiro Etal First article on mammography screening

10. 1997 ; Niklason Etal Advent of breast tomosyntesys

11. 2000 Food And Drug Administration Approved


Digital Mammography
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MAMMO ( CONTRAST ENHANCED MAMMOGRAPHY (CEM)
Study online at https://quizlet.com/_egdp0f

12. 2011 Food And Drug Administration APPROVED


CEM

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