MAY 2004

1-Behcet syndrome which HLA: B51

2-Erythema multiforme associated with herpes simplex which HLA:
a/ B1 b/B12
c/B15 d/ B?
3- Chronic bullous disease of childhood, which antigen: 71KDA
a/ collagen VII
4- in HIV, white superficial onychomycosis, which organism:
a/ T.rubram b/T.mentagrophyte
5- Cryptococcus neoformans ,stain
6-Inflixibam, mechanism of action;
7- Dermatitis herpetiformis, with dapsone , what will reactivate the disease:
a/ ketoconazole b/cimetidine
8-wolfe…….? Reaction with which drug:
a/ azathioprine b/ cyclosporine
9- more systemic photosensivity, which drug : griseofulvin
10-8 years boy with erythema migrans, best drug: penicillin
11- young boy with gram negative folliculitis , best drug:
a/ ciprofloxcillin b/ doxycycline
12-to preserve typhus, which you will use;
a/ formaline b/alcohol
c/gluteraldehyde d/water

13- in pathogenesis of psoriasis, which expression will be decreased:

a/ intermediate filament

d/size of keratohyaline granules b/ filaggrin c/ integrin

14- in vitro when you add acitretine to psoriatic skin what will be upregulated:
a/fillagrin

15- when you treat psoriatic pt with calcitronin, which IL will be increased:
a/ IL-10 b/1L-8 c/IL-6
16-gene NEMO for which syndrome:
17-premature aging, perioral furrow, delayed teething, hypohydrosis,brittle hair,? Syndrome:
a/ cokayene syndrome b/ Werner syndrome
c/ Ruthmond Thomson syndrome
18-pyoderma gangerosum, associated with which paraproteinemia: IgA
19-staining of michealis- gutmann bodies:
20-RXR- what natural retinoic acid binds:
a/ 9 cis-retinoic acid b/all trans retinoic acd
c/oxo-all trans retinoic acid
d/4 hydroxy-all trna retinoic acid e/ carotene
21- RAR: most common subtype: alph/ beta/ gamma
22-in azathioprine what you will determine before giving to pt:
a/ TMPT
23- Thioguanine side effect:
a/ myelosuppression b/ git upset
c/hepatotoxcity
24- which drug causes phtosensivity: griseofulvin
25- minocycline, which side effect causes: lupus like
26- which drug causes linear IgA dermatosis: vancomycin
27-high dose of acyclovir, side effect: acute renal failure
28-facial artery branch for supra trochlear artery: from ophthalmic artery
> branch from internal carotid artery
29-stain for leshmaniasis:
30- erythema necrolytic migratory: zinc deficiency
31- oroya fever, vector: sandfly
32-HPV,E2,4,5,6…..infections of:
a/ stratum corneum b/ basal, suprabasal
c/mid melphegi
33- methemoglobulinemia, in which drug: methotrexate
34-long acting local anaesthesia: bupivacaine
35-best suture for horizontal subcuticular for easy removal:

a/braided nylon b/silk

c/catgut
36-chemical peeling, deep: phenol
37- pt want to feed goat, infection on her hand:
a/parapox virus b/ortho c/pox virus
38- Kaposi sarcoma: HHV8
39-5th disease; parvovirus 19
40-urticaria in which amyloid:
primary/ nodular/ lichenoid/ macular
41- eryspeloid, common site:
a/hands b/face c/foot
42-tinea corporis gladitorum, common site:
a/arms b/chest c/face d/back
43-lethal midline granuloma:
a/lymphoma b/mycobacterium
44-venom sphingomylinase, type of enzyme
a/esterase b/phospholipase c/protease d/hydrolase
45-exofytic scalp lesion, immunohistochemistry:
a/vimentin b/cytokeratine c/spindle cell
d/S-100 e/factor VIII
46-HIV pt with lipodystrophy, lab abnormality:
a/ high TGA b/ high HDL
47-pitting nail characteristic which:
a/nethorton syndrome b/ alopecia areata
48-to differentiate HSV-1 from HSV-2 fast and specific:
a/serology
b/ T zank smear c/viral culture
49-which is X- linked:
a/hypodermal hypoplasia
b/cutis laxa c/estogenic imperfecta d/ehlers danlos
50-mucus cyst of digit arise from: fibroblast
51-sebaceous nevus in scalp, most common tumor:
a/scc b/sebaceous ca c/cylindroma
d/tricho?blastoms/ epithelioma
52-cause of interdigital blastomycosis
a/ candida b/pseudomona aeuroginosa
c/blastomycetis
53-drug that cause subacute cutaneous SLE :
a/trimethoprim b/allopurinol c/phenol
54-acquired deficiency of C1 –esterase inhibitors present in:
a/ SLE b/ antiphospholipid syndrome
55- alpha- antitrypsine deficiency associated panniculitis, most common presentations:
a/ulcerative nodules b/ nodules on lower limbs
c/painless
56- defect in melanosomes transfer in which disease:
a/piebaldism b/ albinism
57- scarring in which disease :
a/PLEVA b/PNP c/pityriasis alba d/pityriasis rosea
58-? …. Striata in which disease:
a/focal dermal hypoplasia
59- hepatitis b in:
a/poly arteritis nodosa b/SLE
60-hepatitis c:
a/autoimmune thyroiditis b/rheumatoid arthritis
c/SLE
61-TIE-2 mutations in :
62-mutations in ATPase CA channel in which disease:
a/dyskeratosis b/ focal hyperplasia
63-2 weeks old baby with progressing enlarging hemangioma lt eye, what you do:
a/observation b/ laser
64-which laser absorbs water: erbium:yag
65-phton in which wave length acquire high energy:
a/UVC b/visible light
c/UVA d/INFRARED
65-target of bullous impetigo:desmoglein 1
67-mutation in psoriasis decreased in:
a/keratin 6 b/ ki 67 ag
68-topical macrolids decrease:
a/PG b/lymphocyte c/neutrophil
d/ag presentations
69-in lepromatous leprosy which increased:
a/IL-2 b/IL-4 c/TNF-ALPHA
d/IF- ALPHA
70-in clear cell acanthoma, which enzyme is increased:
a/ hyalourinidase
71-which is fungicidal: terbinafine
72-in erythrasma, which porphyrine is responsible for fluorescence:
a/coproporphyrine b/uroporphyrine III
c/ ALA
73-if you examine under microscopy, trichothiodystrophy:
a/ alternating polarizing zones
74-treatment of choice in norcordiasis:
a/sulfamethoxazole-trimethoprime
75-in hereditary ataxia telengiectasia, most common cancer:
76-eccrine innervation:
a/cholinergic- sympethatic
77-which drug is contraindicated with erythromycine:
a/terfinadine b/probencid c/folic acid
d/cimetidine e/ketoconazole

-*** MATCHING:
78-incontitence pigmentosa
79-bazex syndrome
80-medulloblastoma
81-tripe hand
82-floride cutaneous papillamatosis
-chronic renal failure
-oesophagus ca
-gastric ca
-merckel cell ca
- heart failure
83-syphillis
83-yaws
84-pinta
85-erythema migrans
86-chronic acrodermatitis atrophica
- T. pallidum
-T.pallidum ssp pertenue
-T. carateum
-borrelia burgdorferi

87-CREST
88-MCTD
89-SLE
90-sjogren syndrome
91-drug induced SLE
-anti centromere antibody
- URNP
-Sm antibody
-anti Ro/SS-A
-Histones

92-MHC class 11
93-MHC class 1
94-ICAM-1
95-B7
96-LAF-3
-CD4
-CD8
-LFA-1
-CD28
-CD2

* IN MICROSCOPIC EXAMINATION OF
97-COCCIDOMYCOSIS
98-PARACOCCIDOMYCOSIS
99-HISTOPLASMOSIS
100-SPOROTRICOSIS
101-BLASTOMYCOSIS
-spherules
- septate with buds
-grows in macrophages as yeast and grows outside as mould
-cigar shaped
-double contoured wall

*MATCH THE GENE DEFECT

102-epidermolysis bullosa simplex
103-JEB
104-DystrophicEB
-K5,14
-Laminin5
-collagen7
-