Arab board Dermatology

Part 1 – February 2021

Done by Dr . Mohammad Al-ahmad
00962785378899
 1- Langerhans cells originate from :
A- Ectoderm
B- Neural crest
C- Bone marrow
D- Mesoderm
E- Lymph node

Answer : C

2- Which of the following TLR is involved in recognizing

lipopolysaccharide :
A- TLR 3
B- TLR4
C- TLR7
D- TLR5

Answer : B

3- Sebaceous glands of superficial eyelid margin are known as :

A- Moll's gland
B- Gland of zeis
C- Meibomian gland
D- Montogomery Gland
E- Tyson's gland

Answer : B
 4- Which of the following cytokines is involved in stimulating
adaptive immunity :
A- IL-1
B- IL-2
C- IL-10
D- IFN-Alpha

Answer : B

5- 1 Melanocyte has contact with :

A- 6 keratinocytes
B- 12 keratinocytes
C- 18 keratinocytes
D- 30 keratinocytes
E- 36 Keratinocyte

Answer : E

6- What is the primary component of sebum :

A- Cholesterol
B- Cholesterol ester
C- Squalene
D- Wax ester
E- Triglyceride

Answer : E
7- What test is most appropriate to identify a new genetic
mutation :
A- Nucleic acid array
B- Western blot
C- PCR
D- Reverse transcription PCR
E- DNA sequencing

Answer : E

8- Eosinophils are activated by which interlukin :

A- IL-1
B- IL-2
C- IL-3
D- IL-4
E- IL-5

Answer : E

9- Langerhans cell don’t express which of the following marker :

A- CD35
B- CD1a
C- MHCII
D- CD54
E- CD80/86

Answer :A
10- Which interlukin is responsible for neutrophilic chemotaxis
:
A- IL-1
B- IL-5
C- IL-8
D- IFN-Alpha
E- TGF-Beta

Answer : C

11- What is spectrum of UVA2 light :

A- 460-400 nm
B- 400-340 nm
C- 340-320 nm
D- 320-290 nm
E- 290-200 nm

Answer : C

12- Pain is detected by which of the following:

A- Pacini corpuscle
B- Meissner's corpuscle
C- Ruffini corpuscle
D- C-type fiber
E- Merkel cell

Answer : D
13- 5-alpha reductase convert testosterone to :
A- Androstenedione
B- Dihydrotestesterone
C- DHEA
D- 17-Alpha hydroxyprogesterone
E- 17-Alpha hydroxypregnenoline

Answer : B

14- Which of the following is most closely associated with

psoriasis :
A- HLA-B6
B- HLA-DR2
C- HLA-DQ8
D- HLA-DR6
E- HLA-Cw6

Answer : E

15- Which molecule or group of molecules is an extracellular

components of desmosome :
A- Keratin Filament
B- Desmoglein & Desmokeline
C- Plakopglopin & plakophilin
D- E- and P-Cadherine
E- Desmoplakin

Answer : B
16- Granulation Tissue is initially composed of :
A- Collagen I
B- Collagen II
C- Collagen III
D- Collagen IV
E- Collagen VI

Answer : C

17- Which of the following is able to Cross the placenta :

A- IgA
B- IgD
C- IgG
D- IgE
E- IgM

Answer : C

18- What of the following is the most inner portion of hair :

A- Henle's layer
B- Hair shaft cuticle
C- Inner root sheath
D- Huxely's layer
E- Glassy membrane

Answer : B
19- Topical Medication with antiscabietic , against acne &
seborrhea with Antiseptic Effect :
A- Crotamiton
B- Erythrmomycin
C- Precipitated Sulfur
D- Benzoyl peroxide
E- Tannic acid

Answer : C

20- Which of the following is melanogenic inhibitor :

A- Nitric Oxide
B- Catecholamine
C- Sphingolipid
D- Neurotrophins
E- Endothelin -1

Answer : C

21- The average density of scalp vellus and terminal hair in

neonate is :
A- 250 / cm2
B- 1135/cm2
C- 615/cm2
D- 485/cm2
E- 300/cm2

Answer : B
22- What is the most frequently affected organ in GFHD :
A- Stomach
B- Liver
C- Small intestine
D- Esophagus
E- Skin

Answer : E

23- Island of sparing is characteristic for :

A- PR
B- PRP
C- Parapsoriasis
D- Psoriasis
E- MF

Answer : B

24- Fixed drug Eruption is considered :

A- Type I HSR
B- Type II HSR
C- Type III HSR
D- Type IV HSR
E- Type V HSR

Answer : D
25- Effects of salicylic acid include all of the following except :
A- Antiscabietic effect
B- Anti-inflammatory
C- Keratolytic
D- Keratoplast
E- Antimycotic

Answer : A

26- MHC II is located on chromosome

A- 1
B- 6
C- 12
D- 17
E- 9

Answer : B

27- Which Statement doesn’t apply to mast cell mediator

angioedema without wheals :
A- Can be seen as part of chronic spontaneous urticaria
B- Can be seen as a part of inducible urticaria
C- Bowel obstruction is not seen
D- Bradykinin is the main mediator
E- Laryngeal edema / obstruction is not a feature

Answer : D
28- Nikolsky's sign is positive in all of the following except
A- SSSS
B- Bollous pemphegoid
C- EM
D- Pemphigus Vulgaris
E- SJS

Answer : B

29- Row of Tombstone is histology occur in :

A- Pemphigus vulgaris
B- BP
C- Herpes zoster
D- Irritant dermatitis
E- DH

Answer : A

30- Most immunoglobulin type expressed in neonate is :

A- IgA
B- IgG
C- IgE
D- IgD
E- IgM

Answer : B
31- Which of the following hormones is secreted by posterior
pituitary glands :
A- GH
B- FSH
C- Prolactin
D- Vasopressin
E- ACTH

Answer : D

32- The embryonic epidermis is morphologically similar to

adult skin by :
A- Mid third trimester
B- Mid first trimester
C- Second trimester
D- 8 weeks gestation
E- 40 weeks gestation

Answer : A

33- Koilonychia may be seen most commonly in deficiency of :

A- Zinc
B- Iron
C- Folic Acid
D- Magnesium
E- Calcium

Answer : B
34- An immunological disorder characterized by abnormal high
titer in immunoglobulin :
A- Thymic hyperplasia
B- Severe combined immunodeficiency
C- Hypogammaglobulinemia
D- Gammopathy
E- Agammaglobulinemia

Answer : D

35- Natural killer cells don’t :

A- Contain serine protease
B- Kill only by damaging the target cell outer membrane
C- Contain TNF
D- Contain Perforin
E- Respond to interferon

Answer : B

36- Polymorphonuclear neutrophils :

A- Is a bone marrow stem cell.
B- Is closely similar to a mast cell.
C- Contains microbicidal cytoplasmic granules.
D- Is not a professional phagocytic cell.
E- Has granules which stain with eosin

Answer : C
 37- Hertogh sign is observed in :
A- Lichen planus
B- PR
C- PRP
D- Atopic dermatitis
E- Lichen striatus

Answer : D

38- One of the followings is Occasional side effect of MTX :

A- Nausea
B- Abdominal pain
C- Headeche
D- Loss of libido
E- Fatique

Answer : D

39- Test which detect the presence of multiple number of

antigen :
A- Comlement fixation test
B- Passive latex agglutination
C- Direct fluorescent antibody test
D- Indirect fluorescent antibody test
E- Immuno-Electrophoresis

Answer : E
40- Which of the following is found in fungal and mycoplasma
and absent in bacteria :
A- Chitin
B- Chlorophyll
C- Lipid
D- Muramic acid
E- Sterol

Answer : E

41- Lanolin refers to :

A- E-Wax
B- Soft parrafine
C- Hydrous wool fat
D- The obrama oil
E- None of the above

Answer : C

42- One of the following treatment for scabies is FDA approved

for infant ≥ 2 months of age :
A- Sulfur ointment 5-10%
B- Lindane lotion 1%
C- Permethrin cream 5 %
D- Crotamiton lotion or cream 10%
E- Ivermectin 3 mg tab

Answer : C
43- Which of the following is not used for treatment PVC :
A- Topical selenium
B- Topical miconazole
C- Topical ketoconazole
D- Systemic grisufulvin
E- Systemic fluconazole

Answer : D

44- Ballooning degeneration occur in :

A- Thermal burn
B- Electrical burn
C- Herpes simplex
D- Pemphigus
E- EM

Answer : C

45- Which of the following is not antioxidant :

A- Zinc
B- Green tea ( Tea Polyphenol)
C- Vitamin C
D- Vitamin E
E- None of the above

Answer : E
46- In case of shock which of the following compensatory
factor is responsible for increasing BP :
A- Carotid body chemoreceptor
B- Ischemic brain receptor
C- Brain-bridge reflex
D- Arterial baroreceptor reflex
E- Atrial stretch receptor

Answer : D

47- Dose of dexamethazone which is equivalent to 80 mg

prednisolone is :
A- 4 mg
B- 12 mg
C- 20 mg
D- 40 mg
E- 80 mg

Answer : B

48- One of the following is class D2 Corticosteroids :

A- Betamethazone dipropionate
B- Betamethazone valerate
C- Hydrocortisone valerate
D- Clobetazole dipropionate
E- Mometazone furate

Answer : C
49- One of the following is not produced by Th2 :
A- IL-4
B- IL-9
C- IL-1
D- IL-5
E- IL-6

Answer : C

50- The following is true about chemistry of proteoglycan

A- Core protein are attached to branched suger
B- Attachment to protein core occur at site of amino acid glycine
C- Attachment to core is through a specific oligopolysaccahride
chain
D- Sugar chains can have many suger
E- Fructose is a major component

Answer : D

51- Ecthyme is :
A- Crusted impetigo
B- Ulcerative impetigo
C- Cicinate impetigo
D- Bollous impetigo
E- None of the above

Answer : B
52- One of the following statement is correct about Erythema
nodosum :
A- Malignancy is a frequent cause
B- Underlying cause is found in all cases
C- Nodule commonly ulcerate and heal with scarring
D- Streptococcal URTI is most triggering factor
E- This is the least type of panniculitis

Answer : D

53- Birbeck's granules typical of histocytosis are present in :

A- Melanocyte
B- Keratinocyte
C- Langerhans cell
D- Granulocyte
E- Histocytes

Answer : C

54- Which of the following is not a feature of behcet disease :

A- Oro – genital ulcer
B- Blindness
C- Recurrent DVT
D- Pulmonary fibrosis
E- Pathergy test

Answer : D
55- The key enzyme in melanin biosynthesis pathway is :
A- Tyrosinase
B- 5,6-DHI oxidase
C- 5,6-DHICA polymerase
D- Dihydroxyphenylamine synthase
E- Tyrosinase- related protein 1

Answer : A

56- Which of the following is part of alternative complement

cascade system :
A- C1
B- C1 INH
C- C3
D- C5a
E- Anaphylotoxin

Answer : C

57- Which of the following is cytoskeleton anchor in adherent

junction :
A- Plectin
B- Actin
C- Alpha-catanin
D- E-cadherin
E- Myosin

Answer : B
58- The target lesion is present in :
A- SJS
B- TEN
C- Erythema multiforme
D- Impetigo
E- SSSS

Answer : C

59- The most important cell in wound healing is :

A- Fibroblast
B- Neutrophil
C- Macrophage
D- Lymphocyte
E- Mast cells

Answer : C

60- Stratum lucidum is present mainly in :

A- Scalp
B- Genitalia
C- Leg
D- Back
E- Palms & soles

Answer : E
61- One of the following is not mediator of pain :
A- Tryptase
B- Prodtaglandin E
C- Substance P
D- M-opioid receptor agonist
E- Nerve growth factor

Answer : D

62- Which cytokines is not produced by keratinocyte :

A- IL-1
B- IL-3
C- IL-2
D- TNF-Alpha
E- IL-6

Answer : C

63- Ash leaf is characteristic of :

A- NF-1
B- NF-2
C- Tuberous sclerosus
D- Cowden disease
E- Gardner disease

Answer : C
64- Plasma cell do not reside in one of the following :
A- Bone marrow
B- Blood
C- Respiratory tract
D- GIT
E- Spleen

Answer : B

65- Which of the following is arranged in a network formation :

A- Elastic tissue
B- EC matrix
C- Papillary collagen
D- Reticular collagen
E- Filamentous protein

Answer : A

66- Glomus cells are primirly found on :

A- Hands & feet
B- Trunk
C- Lateral thigh
D- Genital skin
E- Face

Answer : A
67- Pediculus humanus var corporis is vector for :
A- Endemic typhus
B- Epidemic typhus
C- Q fever
D- Rickettsiaplox
E- RMSF

Answer : B

68- Which of the following joints not involved in rheumatic

fever :
A- Elbow
B- Knee
C- Wrist
D- Ankle
E- Proximal interphalengeal

Answer : E

69- One of the following stains blue by giemsa:

A- Amyloid
B- Mast cell granules
C- Nuclei
D- Acid fast organism
E- Sulfared mucopolysaccharides

Answer : C
70- Which of the following is not DDx of grenz zone :
A- Granuloma faciale
B- Granuloma annulare
C- Lepromatous leprosy
D- Leukemia cutis
E- Lymphoma cutis

Answer : B

71- Which of the following is secondary lesion :

A- Macule
B- Papule
C- Vesicle
D- Excoriation
E- Pustule

Answer : D

72- Naked granuloma is characteristic of :

A- Sarcoidosis
B- Granuloma annulare
C- Cutaneous TB
D- Leishmaniasis
E- Foreign body granuloma

Answer : A
73- One of the following is not STD :
A- Scabies
B- Molluscum contagiousum
C- Condylomats accuminata
D- Eczema herpeticum
E- Herpes progenitalis

Answer : D

74- Which of the following topical agent can cause ACD :

A- Capsaicin
B- Doxepin
C- Menthol
D- Tacrolimus
E- Pimecrolimus

Answer :B

75- Krause end bulbs are :

A- Adaptive mechanoreceptor found on weight bearing sites that
respond to vibrational stimuli
B- Found on the vermilion border of lips
C- Located in dermal papillae in digital skin
D- Located in deep dermis and within subcutis in weight bearing
site of body
E- Found at orifices of hair follicle and particularly sensitive to
cold

Answer : B
76- The prominent collagen in fetal skin is :
A- Collagen I
B- Collagen II
C- Collagen III
D- Collagen IV
E- Collagen V

Answer : C

77- Which of the following assess hepatic fibrosis prior to liver

biopsy in case of MTX :
A- Procollagen I
B- Procollagen II
C- Procollagen III
D- Procollagen IV
E- Procollagen V

Answer : C

78- Factor XIII is positive in :

A- Kaposi sarcoma
B- Langerhans cell histocytosis
C- Merkle cell carcinoma
D- Neurofibroma
E- Dermatofibroma

Answer : E
79- String of pearls ( crown of jewels ) is associated with :
A- IgA Pemphigus
B- Chronic bollous disease of childhood
C- DH
D- Bollous pemphigoid
E- Pemphigus vulgaris

Answer : B

80- Which of the following must be in atopic dermatitis

A- Itchy skin lesion
B- Eczema in flexure
C- Less than 2 years
D- Xerosis

Answer : A

81- About stem cells which of the following is incorrect :

A- Self renewal is unlimited
B- Potential for differentiation is multipotent
C- Cycling in normal epidermis is slow
D- Proliferative potential is high
E- Growth in culture is small abortive clone

Answer : E
82- In leprosy which of the following is correct :
A- Lepromaous leprosy is multibacillary
B- Nerve invasion is late in tuberculoid type
C- Numerous patches are characterized in tuberculoid type
D- Well demarcation is feature of lepromatous type
E- All of the above

Answer : A

83- The best temperature for virus transport is :

A- 4 C
B- -20 C
C- 25 C
D- 42 C
E- 37 C

Answer : B

84- Which properity will not differentiate fungi from bacteria:

A- Formation of aerial hyphae in culture
B- Possession of mitochodria
C- Presence of Nuclear membrane
D- Production of sexual spores
E- Synthesis of cell wall chitin

Answer : A
85- Which property can differentiate Chlamydia from virus:
A- Ability to elicit delayed hypersensitivity
B- Sensetive to tetracyclines
C- Existence as obligate intracellular parasites
D- Filterable nature of Infection unit
E- Formation of inclusion bodies in infected cell

Answer : B

86- Which organism is classed as eukaryotic :

A- Candida albicans
B- Micropolyspora faeni
C- Nocardia asteroids
D- Streptobacillus moniliformis
E- Streptomyces madurae

Answer :A

87- Which of the following is not feature of HPV :

A- Non enveloped
B- DsDNA
C- Family of papoviredia
D- Cervical cancer is caused by HPV 16 & 18
E- Large virus

Answer : E
88- Aspirin can cause which of the following :
A- Urticaria
B- Popular urticaria
C- Discoid Eczema
D- Heridatary Angioedema
E- ACD

Answer : A

89- Merkel cell marker is :

A- CK20
B- CK 10
C- CK 15
D- Loricrin
E- Envoplakin

Answer : A

90- Layer most involved in spongiosis is :

A- S. basal
B- S. spinosus
C- S.Granulosum
D- S.lucidum
E- S.corneum

Answer: B
91- Several of Complemnt component are :
A- Antibodies
B- Hormone
C- Cytokines
D- Enzymes
E- Glycolipid

Answer : D

92- 35 years present With perifollicular violaceous patches of

cicatricial alopecia and biopsy show BMZ vacular degeneration
and civate body most likely Diagnosis is :
A- DLE
B- SLE
C- Lupus vulgaris
D- LPP
E- Lichen sclerosus

Answer : D

93- Pox virus is :

A- DNA Virus
B- RNA virus
C- Roseola is an example
D- Big molecular weight
E- 200-300 nm diameter

Answer : A
94- The target in Pemphigus foliaceous is :
A- Dsg 1
B- Dsg 3
C- TGM 1
D- TGM 3
E- Dsc 3

Answer : A

95- Mollouscum contagiosum is :

A- Primary lesion is nearly vesicles
B- In adult is sexual transmitted disease
C- RNA virus
D- Erythema multiforme coexist
E- In some children usually all infection by MCV2

Answer : B

96- Which of the following is not topical antipruritic :

A- Calamine
B- Benzoyl peroxide
C- Menthol
D- Crotamion
E- Camphor

Answer : B
97- The systemic agent which show effect in renal pruritis :
A- Doxepin
B- Nalfurafine
C- Paroxitime
D- Naloxone
E- Mirtazapine

Answer : B

98- Number of hair emerging from each hair pores on the

beard or body :
A- 1
B- 2
C- 3
D- 4
E- 5

Answer : C

99- Hepatitis C is associated with :

A- Lichen planus
B- Eczema
C- Psoriasis
D- Urticaria
E- Pyoderma gangrenosum

Answer : A
100- The epithelium that lies on the volar surface of the digit is :
A- Nail bed
B- Nail matrix
C- Nail plate
D- Hyponychium
E- Eponychium

Answer : D

101- Which of the following is correct about perlecan :

A- Attacment to lamina densa

102- An important proteoglycan in the dermis is :

A- Dermatan

103- An elderly women present with well demarcated red

tender warm plaque on calf associated with fever . the
diagnosis is :
A- Erysipelas

104- Most abundant in dermis is :

A- Fibronectin
105- Which of the following is transmembrane
A- Cadherine

106- Which of the following excarpate gutate psoriasis :

A- Excaerbate by streptococcal Infection

107- About leishmania life cycle which of the following is

incorrect :
A- Amastigote back to promastigote
B- Promastigote Return back to amastigote
C- Replicate in reticulendothelial system
D- Larvea inside its GIT
E- ??????

108- Blood vessels in dermis differ from those of body by being :

109- Apoptosis :

110- Which of the following is correct about fibroblast :

111- Stain for fungal cell wall is :

A- PAS stain
112- All of the followings are feature of secondary syphilis
except :
A- Bollous lesion

113- Which cell differrente and going up :

A- Transient amplifying cell

114- All of the following are true about mycobacterium except :

A- Destroyed by NAOH

115- Proteglycan that regulate thrombin is :

A- Heparin

116- Which of the following is correct about free nerve ending

‫جزيل الشكر لكل من ساعد يف تجميع اسئلة االمتحان‬

‫وبالتوفيق للجميع‬