DETAILED School PAMUKID NATIONAL HIGH Quarter 3RD QUARTER

LESSON SCHOOL
PLAN Teacher MARIO D. ROMERO JR. Designation STUDENT TEACHER
Date MARCH 06, 2024 Learning Area/Grade Science 10
Teaching Schedule 8:30-9:30 AM

I. OBJECTIVES
A. CONTENT STANDARDS The learners demonstrate an understanding of how genetic engineering is used to produced novel
products.
B. PERFORMANCE
STANDARDS
C. LEARNING Describe the process of genetic engineering (S11/12LT-IIej-17)
COMPETENCIES
Specific Objectives At the end of the lesson students should be able to:

1. Describe the process of producing recombinant DNA;

2. cite the advantage and disadvantage of genetic engineering, and
3. create a Venn diagram that compares genetically modified organisms and non-genetically
modified organisms.

II. CONTENT Genetic Engineering

III. LEARNING RESOURCES

A. Module Science 10 Learner’s Material, page 292

B. Other learning Teacher’s Guide pages Pg 179, https://www.youtube.com/watch?v=-SPRPkLoKp8
resources
C. Materials TV, laptop, Manila Paper, Marker
D. Integrated Values Participation, Collaboration and Appreciation
E. 21st Century Skills Critical thinking, understanding, observing, communication and collaborative skills
IV. PROCEDURES
a. Method 7E’s (Elicit, Engage, Explore, Explain, Elaborate, Evaluate, and Extend)
b. Strategies Interdisciplinary, Visualization, Collaborative learning, Critical thinking skills, Inquiry-based

METHOD TEACHER’S ACTIVITIES STUDENTS’ ACTIVITIES

A. BEFORE THE LESSON
Preliminary Activities:
Greetings Good morning class! Good morning, Ma’am!

How’s your morning? ” Good morning, Sir!”

Prayer Nice to hear that! Please stand for our prayer. “Good Sir!”
Miriam, please lead the prayer. (The students will stand and pray.)

Securing the cleanliness Before you take your seats, kindly pick up all the
pieces of paper near you and please arrange your (Students will pick up the pieces of dirt and
chairs properly. arrange their chairs.)
Checking of Attendance
Class beadle did you already check the attendance
of your classmates?
Checking of Assignment “Yes Sir”
Thank you. Last meeting, I gave you an assignment,
please pass it in front and I’ll check it later. (The students will pass their assignment)

Let me remind you again about our classroom rules.

(The teacher will present the classroom rules)

Is that clear?
“Yes Sir.”

B. DURING THE LESSON

ELICIT

Reviewing the previous Last meeting, we discuss about chromosomal

lesson or presenting the mutation.
new lesson Again, what chromosomal mutation? “Sir chromosomal mutations involve changes in
Yes Olive the number or structure of chromosomes.”
 Very good!
What are the four types of chromosomal mutation?
Yes Carmela “Sir the four types of chromosomal are mutations,
deletion, duplication, inversion, and
translocation.”
That’s correct! Who can differentiate these
chromosomal mutations?
Yes Jonathan “Sir, deletion involves the loss of all or part of a
chromosome. Duplication produces an extra copy
of all or part of a chromosome. Inversion reverses
the direction of parts of a chromosome. Lastly,
translocation occurs when part of one
chromosome breaks off and attaches to another.”
Excellent!
It seems like you’ve learned a lot and now ready to
learn something new.
ENGAGE

a) Establishing a Before we formally begin our discussion, I have here (The students will identify the given pictures)
purpose for the a video. I want you to watch this attentively and
lesson write down important details.
(the teacher will present the video)

Okay, class did you understand the video? “Yes Sir!”

b) Presenting What is the main idea of the video? “The main idea of the video is to explain how
examples/ scientists can modify the DNA of living things to
Instances of the give them new traits.”
new lesson Very good! What are the three steps involved in
creating a new trait in an organism, as described in “The three steps involved in creating a new trait in
the video? an organism are: (1) cutting the DNA at a specific
location, (2) inserting a new piece of DNA into the
cut, and (3) letting the cell repair itself.”
Excellent! What is the role of enzymes in the
process of modifying DNA, according to the video?
“Sir enzymes play a crucial role in the process of
modifying DNA by helping to break apart the
double helix and insert new pieces of DNA.”
That’s right! What is the final product of the process
described in the video, and how does it differ from
the original organism? “Sir, the final product of the process described in
the video is a modified organism with a new trait,
which differs from the original organism because
it has a changed DNA sequence.”
Very well said! In connection with that, what do you
think is our topic for today? “Sir, I think our topic for today is all about genetic
engineering.”
Presentation of Lesson That’s right! Our topic for today is all about genetic
Objectives engineering. Throughout our discussion we will be
guided by the following objective. Please read
Loren.
At the end of the lesson, students should be able
to:

1. Describe the process of producing

recombinant DNA;
2. cite the advantage and disadvantage of
genetic engineering, and
3. Create a Venn diagram that compares
genetically modified organisms and non-
genetically modified organisms.
Unlocking of Difficulties Here are the unfamiliar words that we will Gene: A segment of DNA that contains the
encounter as we go on with our topic. instructions for a specific protein or function
Please read.
within an organism.

Engineering: The application of scientific

principles and techniques to design, build, and
 maintain structures, machines, and systems.

Modification: A change made to something, such

as a gene, protein, or organism, that results in a
new characteristic or property.

EXPLORE

a) Discussing new To attain our objectives, let’s have a group activity.

concepts and (The teacher will explain the activity.
practicing new Procedure:
skills #1 1. The class will be group into four groups.
2. Each group will do the activity and answer the
guide questions and choose one presenter.

Is that clear? “Yes Sir”

Before you start working on the activity, here is the

rubrics that I will use to grade your activity. (The
teacher will present the rubric)

You may go now to your respective group. Before I (Students will check the materials”
start the timer, check your materials first.

Do you have any question? clarification? “None Sir”

b) Discussing new If none, I’ll give you 10 minutes to do your activity. If (The students will do the activity)
concepts and you have question or clarification just raise your
practicing new hands. You may now start.
skills #2
EXPLAIN Time is up. Please post your output on the board
and kindly arrange your chairs properly and go back
Developing mastery to your own seat.
(Leads to Formative
Assessment) How was the activity class?
“It was fun and interesting sir.”
I’m glad to hear that. Each group will be given 3
minutes to present their output. Group 1 please (Group 1 will present their work)
present your work now.

Very good group 1. Class, let’s give them five claps. (The class will clap their hands)

Let’s now proceed to the group 2. (Group 2 will present their work)

Excellent group 2! Let’s give them also five claps. (The class will clap their hands)

Let’s now proceed to the group 3. (Group 3 will present their work)

Nice Job group 3! Let’s give them also five claps. (The class will clap their hands)

Now, let’s check your output. (The teacher will

check the answers)

Guide Questions:
1. What are some differences between GMOs and
non-GMOs? “GMOs are modified while the non-GMOs are
natural.”
2. How are GMOs created differently than non-
GMOs? “GMOs have been intentionally altered by humans
through genetic engineering, giving them new
attributes that are not found in non-GMOs. These
changes can include resistance to pests, increased
tolerance to environmental stressors, and
improved nutritional profiles. In contrast, non-
GMOs have evolved naturally over time through
the process of natural selection, resulting in
inherent genetic diversity that is not present in
GMOs”
3. What are some similarities between GMOs and
 non-GMOs in terms of their ability to reproduce and
adapt to their environments? ”Both types of organisms are capable of
reproducing and adapting to their environments,
and they both possess unique genetic traits that
define their species.”
(Teacher will check the student work using the
rubrics.)

Well done class! Do you have any questions so far?

“None Sir”
ELABORATE Now, let’s learn more about this very interesting
topic. (The teacher will present)

Genetic Engineering- a modern biotechnology that

produces transgenic or GM (Genetically Modified)
crops or organism.

Recombinant DNA- DNA from two different species

are joined together. This process uses restriction
enzymes to cleave one organism’s DNA into
fragments and other enzymes to splice the DNA
fragment into a plasmid or viral DNA.

a) Finding practical Today, molecular biologists are finding applications

application of for recombinant DNA technology: from medical
concepts and applications, including gene therapy and vaccines;
skills in daily living DNA fingerprinting used to identify persons
responsible for crimes and provide evidence for
identity of dead persons; to the creation of
genetically modified crops that are resistant to
pesticides, or that make extra vitamins and
minerals; to bacteria that can clean oil spills. While
the applications of recombinant DNA technology
are numerous, its limitations are its potential effects
on our ecosystem.

However, genetic engineering also raises several

concerns. The long-term effects of genetic
engineering on human health and the environment
are not yet fully understood, and there is a risk of
unintended consequences. Furthermore, the
possibility of genetic engineering being used for
malicious purposes, such as creating biological
weapons, is a concern that cannot be ignored.
Moreover, the cost and accessibility of genetic
engineering technology can limit its availability to
only certain segments of society, which can
exacerbate existing social and economic disparities.

What are the similarities and differences of

Genetically modified organisms (GMOs) and non-
genetically modified organisms (non-GMOs)? “Genetically modified organisms (GMOs) and non-
genetically modified organisms (non-GMOs) are
different in some ways. GMOs are changed by
scientists to have special traits, like being able to
grow in hard conditions or having more nutrients.
Non-GMOs don't have these changes because
 they haven't been altered by humans. They just
grow naturally.”
Very good. Another difference is that GMOs are
usually grown in controlled places, like farms, while
non-GMOs can grow anywhere. This means that
GMOs are easier to take care of and can be made to
grow faster, but non-GMOs can be affected by
things like weather and soil quality.

b) Making To sum up our discussion what is the process of

generalization producing recombinant DNA? “Sir the process includes isolation of plasmid, DNA
and abstraction cut by the enzyme, gene inserted in the plasmid,
about the lesson recombinant plasmid is inserted back in the
bacterium and the new gene directs bacterium to
make new proteins.”
Excellent! What is the advantage and disadvantage
of genetic engineering? “Sir the advantages and disadvantages include:”
Advantages:
 Increased crop yields
 Improved medical treatments
 Enhanced food production
 Reduced dependence on pesticides
Disadvantage
 Unknown long-term effects
 Ethical concerns
 Potential for misuse
 Cost and accessibility

Very Good! What are some differences between “MOs (Genetically Modified Organisms) are
GMOs and non-GMOs? organisms whose genetic material has been
altered using genetic engineering techniques,
allowing for the introduction of new traits or
characteristics. Non-GMOs, on the other hand, are
organisms that have not been genetically
modified and remain in their natural state.”
Very good! Do you have any questions?
None Sir!

C. AFTER THE LESSON

EVALUATE Okay let’s test if you really understand our
Evaluate Learning discussion today. Please get ¼ sheet of paper, we
will have a quiz.

I. Multiple Choice. Choose the letter of the correct

answer.

1. What is the result of the recombinant DNA

process?
a) The bacterium produces a new protein product
b) The plasmid is replicated and passed on to
subsequent generations
c) The bacterium becomes resistant to antibiotics
d) The bacterium undergoes a change in its genetic
code

2. Where does the gene for protein come from in

the recombinant DNA process?
a) It is synthesized in vitro
b) It is taken from another cell
c) It is derived from the bacterial chromosome
d) It is obtained from a virus

3. What is the advantage of using recombinant DNA

technology?
a) It allows for the production of large amounts of a
protein product
b) It enables the introduction of new genes into an
organism
 c) It allows for the modification of the bacterial
chromosome
d) It provides a way to create genetically modified
organisms

II. Enumeration
4. Give one advantage of Genetic Engineering
5. Give one disadvantage of Genetic Engineering

III. Essay
6-10. Using Venn Diagram what is the difference
between GMOs and non-GMOs?

EXTEND Give five recent products or development in genetic

engineering.

That’s all for today class and goodbye!

Goodbye Sir!

V. REMARKS

VI. REFLECTIONS

Prepared by:

Mario D. Romero Jr.

Student Teacher

Observed by:

Jean I. de Los Santos

Teacher II.

Noted by: Noted by:

Grizelein D. Abiog Fe L. Sibulo

Head Teacher III. Principal II

RUBRIC FOR ACTIVITY

CRITERIA Excellent Proficient Adequate Limited
5 4 3 2
 Participation Group member Group member Group member Group member did not
participate fully in participate in almost participate in few participate in any
every discussion and every discussion and discussions and discussion and
decision. decision. decision. decision.

Students spoke clearly Students spoke clearly Student did not speak Student did not present
Oral Presentation and concisely and and concisely, seemed very clearly or or was not prepared to
rehearse their part of to practice a little for concisely, didn’t seem present.
the presentation. the part of the to practice.
presentation.

Correct Answers All the answers are One or two incorrect Three or four incorrect Five or more incorrect
correct answers. answers answers.
.

Finished the activity Finished the activity on Finished the activity Finished the activity
Timeliness before the given time. time. two minutes after the five minutes after the
given time. given time.

RATING SCALE:

20 - 100

19 - 98

18 - 96

17 - 94

16 - 92

15 - 90

14 - 88

13 - 86

12 - 84

11 - 82

10 - 80

Activity Sheet
“COMPARE ME!”
Objectives:
 Create a Venn diagram that compares genetically modified organisms and non-genetically modified organisms.

Materials:

 Activity Sheet
 Manila Paper
 Marking pen

Procedure:

1. Read the information provided below.

2. Create a Venn diagram that compares genetically modified organisms and non-genetically modified organisms.
3. Answer the guide questions.

Genetically modified organisms (GMOs) and non-genetically modified organisms (non-GMOs) share some commonalities, but they
also have distinct characteristics. Both types of organisms are capable of reproducing and adapting to their environments, and they
both possess unique genetic traits that define their species. However, GMOs have been intentionally altered by humans through
genetic engineering, giving them new attributes that are not found in non-GMOs. These changes can include resistance to pests,
increased tolerance to environmental stressors, and improved nutritional profiles. In contrast, non-GMOs have evolved naturally
over time through the process of natural selection, resulting in inherent genetic diversity that is not present in GMOs. One key
distinction between GMOs and non-GMOs lies in their genetic makeup. GMOs have had their genomes intentionally altered by
humans, resulting in the introduction of foreign genes or the modification of existing ones. This genetic tampering allows for the
creation of novel traits that would not be possible through natural evolution. Non-GMOs, on the other hand, have not undergone
such manipulation and therefore retain their natural genetic composition. Another difference between the two is the level of control
that humans have over their development. GMOs are created and cultivated under strict controlled conditions, whereas non-GMOs
are subject to the whims of nature and are influenced by a complex array of environmental factors. This lack of control can
sometimes lead to unexpected variations in non-GMO populations, which can be both beneficial and detrimental.

Genetically Modified Non-Genetically

Organisms (GMOs) Modified Organisms
(non-GMOs)

Guide Questions:

1. What are some differences between GMOs and non-GMOs?

2. How are GMOs created differently than non-GMOs?

3. What are some similarities between GMOs and non-GMOs in terms of their ability to reproduce and adapt to their
environments?