Practice Test - 04 Principle of Inheritance and variations 18/03/2023

BIOLOGY

Section A (All Questions Compulsory) (3) Six (4) Eight

7. For law of segregation to study we need cell
1. Which of the following statements for which is:
chromosomal theory of inheritance is incorrect? (1) Haploid
(1) Pairing and separation of chromosomes
(2) Non-meiotic cell
would lead to the segregation of a factor
only. (3) Diploid cell undergoing meiosis
(2) Behaviour of chromosomes is parallel to the (4) Cell undergoing mitosis
behaviour of genes.
(3) The two alleles of a gene pair are located on 8. Linked genes can be separated through:
homologous sites on homologous
chromosomes. (1) Segregation
(4) Chromosomes as well as genes occur in (2) Crossing over
pairs. (3) Independent assortment
(4) Linkage
2. Experimental verification of the chromosomal
theory of inheritance was given by-
(1) Sutton and Boveri 9. Crossing over can separate ___________.
(2) Correns (1) Genes of one gene loci
(3) T.H. Morgan (2) Genes of different gene loci on different
(4) Tschermak chromosome
(3) Genes which are linked
3. Morgan performed _________ on Drosophila.
(4) All of the above
(1) Monohybrid cross
(2) Dihybrid cross
(3) Reciprocal cross 10. Aneuploidy which results in loss of a complete
(4) Both (1) and (3) homologous pair of chromosome is
(1) Trisomy (2) Tetrasomy
4. The cross–over frequencies between the genes P (3) Nullisomy (4) Euploidy
and Q, P and R along with Q and R are 6%, 15%
and 21% respectively. What is the possible
11. In which of the following disorder a single protein
sequence of genes on chromosome?
that is a part of the cascade of proteins involved in
(1) P, Q, R
(2) Q, P, R, blood clotting is affected?
(3) P, R, Q (1) Thalassemia (2) Sickle cell anaemia
(4) Either Q, P, R or R, P, Q (3) Haemophilia (4) Phenylketonuria

5. Frequency of crossing over will be relatively more 12. Mark the correct statement (w.r.t. sickle cell
if: anaemia)
(1) Distance between the two genes is less
(1) Homozygous individuals for HbS are
(2) Distance between the two genes is more
(3) Linked genes are more apparently unaffected
(4) Both (2) & (3) (2) Heterozygous individuals exhibit sickle cell
trait
6. In a cross between double heterozygous tall and (3) Heterozygous individuals are affected as well
round with similar genotype will result in as carrier
___________ genotype. (4) Homozygous individuals for HbA show the
(1) Nine (2) Four diseased phenotype
13. The defect sickle cell anaemia is caused by the
___ of glutamic acid by valine at the 6th position 20. Point mutations are caused by:
of the ___globin chain of the haemoglobin (1) substitution (2) deletion
molecule (3) insertion (4) all of above
(1) Substitution, β (2) Deletion, α
(3) Duplication, β (4) Translocation, α 21. Mutation can be induced by:
(1) radiation (2) temperature
(3) chemicals (4) all of above
14. A normal woman, whose father had colour
blindness, married a normal man. What is the
22. If the haploid number of chromosomes in a plant
chance of occurrence of colour blindness in the
is 12, then the number of chromosomes in
progeny?
monosomic condition is:
(1) 25% (2) 50%
(1) 26 (2) 23
(3) 100% (4) 75% (3) 22 (4) 25

15. In phenylketonuria 23. Which one of the following is a sex linked

(1) Break down of phenylalanine is rapid character:
(2) Accumulation of phenylalanine in body (1) AB blood group in humans
(3) Chromosomal constitution of patient changes (2) White eye in Drosophila
(4) TSD gene situated on chromosome 15 (3) Duffy blood group in human beings
undergoes mutation (4) Vestigial wing

24. A genetic disease, which is never passed on from

16. A species has 2n = 16 chromosomes. How many
father to son is:
chromosomes will be found per cell in each of the
(1) X–chromosomal linked disease
following mutant species?
(2) Y–chromosomal linked disease
I. Monosomic
(3) Autosomal linked disease
II. Autotriploid (4) None of above
III. Trisomic
IV. Double monosomic 25. The given pedigree represents:
V. Nullisomic
The correct sequence of chromosomes for (I to V)
are
(1) 15, 24, 17, 14, 14
(2) 24, 32, 18, 40, 12
(3) 16, 22, 14, 21, 16
(4) 26, 34, 20, 42, 14
(1) Autosomal Recessive
17. White eyes in male fruit fly is determined by a: (2) Autosomal Dominant
(1) dominant gene on X
(2) recessive gene on Y (3) Sex linked Recessive
(3) dominant gene on Y (4) Y- linked
(4) recessive gene on X

18. ZZ/ZW type of sex determination is seen in: 26. Identify the pedigree with Autosomal Recessive
(1) peacock (2) cockroach inheritance.
(3) apple snail (4) human

19. Homologous chromosomes similar in both sexes

are called:
(1) androsomes (2) autosomes
(3) heterosomes (4) none of the above
 (1) chromosome
(4) men are hemizygous and one defective gene
is enough to make colour blind

31. Sex determination in Drosophila melanogaster is

based on
(1) X-Y chromosome mechanism
(2) Genetic balance between the X chromosome
and autosomes
(2)
(3) Chromosome – environment interaction
(4) Pseudoalleles

32. All sons of a couple are colour blind because

(1) Mother is homozygous colour blind
(2) Mother is heterozygous and father normal
(3) Mother is heterozygous and father colour
blind
(4) Mother is normal and father colour blind
(3)
33. Colour blindness is a disease usually affecting
man but the factor for it is transmitted to the
children always by woman. This is because
particular factor is located on
(1) X chromosome
(2) Y chromosome
(3) Both X and Y chromosomes
(4) (4) Autosome

34. If a normal woman marries a colour blind man

then all their
(1) Sons will be colour blind and daughter
normal
(2) Daughters will be colour blind and sons
normal
(3) Children will be normal
27. In β–thalassemia, the affected chromosome is (4) Children will be colour blind
(1) 16th (2) 14th
(3) 13th (4) 11th 35. A colour blind daughter is born when
(1) Father is colour blind, mother is normal
(2) Mother is colour blind, father is normal
28. Thalassemia is
(3) Mother is carrier, father is normal
(1) autosomal recessive disease (4) Mother is carrier, father is colour blind
(2) autosomal dominant disease
(3) sex–linked dominant disease Section B (Attempt any 10 Questions)
(4) sex–linked recessive disease
36. A sex linked recessive gene C produces red green
29. Polyploidy can be induced by the application of colour blindness in humans. A normal woman
(1) auxin (2) kinetin whose father was colour blind marries a colour
(3) colchicine (4) ethylene blind man. Of all the girls born to these parents,
what percentage is expected to be colour blind?
(1) 25 percent (2) 50 percent
30. More men suffers from colour blindness than (3) 75 percent (4) 100 percent
women because
(1) women are more resistant 37. Sex chromosomes of a female bird are represented
(2) male sex hormone testosterone causes the by
disease (1) XO (2) XX
(3) XY (4) ZW
(3) the colour blind gene is carried by Y-
 (1) Same locus on homologous chromosomes
38. If a genetic disease is transferred from a (2) Same locus on heterologous chromosomes
phenotypically normal but carrier female to only (3) Different loci on homologous chromosomes
some of the male progeny, the disease is (4) Different loci on heterologous
(1) autosomal dominant
(2) autosomal recessive 44. A test cross between AaBb with aabb gave 700
(3) sex–linked dominant parental type then calculate percent of
(4) sex–linked recessive recombinants if total obtain progeny is 1000?
(1) 30 % (2) 70 %
(3) 15% (4) 20%
39. The chromosome constitution 2n-2 of an organism
represents 45. Two non-allelic genes produces the new
(1) Monosomic (2) Nullisomic phenotype when present together but fail to do so
(3) Haploid (4) Trisomic independently then it is called:
(1) Epistasis
40. Sickle cell anaemia (2) Polygene
(I) Follows the same inheritance pattern as that (3) Non complimentary gene
of hemophilia (4) Complimentary gene
(II) Follows the same inheritance pattern as that
of albinism 46. In multiple allele system a gamete possesses:
(III) Is a sex–limited trait (1) Two alleles (2) Three alleles
(IV) Is due to a single recessive point mutation (3) One allele (4) Several alleles
leading to the substitution of a single amino
acid in the β–chain of hemoglobin.
47. Haploid cell have ____________.
The correct statements are
(1) One set of dissimilar chromosomes
(1) All are correct
(2) Two set of chromosomes
(2) All except (I) are correct
(3) One set of homologous pair
(3) All except (III) are correct
(4) One set of similar chromosome
(4) (I) and (IV) are correct

48. A plant with genotype Tt produces pollen with

41. In phenylketonuria, the phenylalanine gets
converted to genotype:
(1) acetic acid (1) T (2) tT
(2) phenyl acetic acid (3) tt (4) t or T
(3) phenyl pyruvic acid
(4) pyruvic acid 49. Which is true about hybridization experiment
conducted by Mendel?
(1) use statistical analysis
42. Haemophilia is due to mutation in (2) mathematical logic
(1) X and Y- chromosomes (3) large sampling size
(2) Y- chromosomes (4) all of the above
(3) X- chromosomes
(4) Autosomal chromosome 50. Mendel selected 14 true breeding
(1) character (2) varieties
43. Multiple alleles are situated on (3) pea plant (4) all of the above
 ANSWER KEY

1. (1) 12. (2) 23. (2) 34. (3) 45. (4)

2. (3) 13. (1) 24. (1) 35. (4) 46. (3)
3. (2) 14. (1) 25. (1) 36. (2) 47. (1)
4. (4) 15. (2) 26. (1) 37. (4) 48. (4)
5. (2) 16. (1) 27. (4) 38. (4) 49. (4)
6. (1) 17. (4) 28. (1) 39. (2) 50. (2)
7. (3) 18. (1) 29. (3) 40. (4)
8. (2) 19. (2) 30. (4) 41. (3)
9. (3) 20. (4) 31. (2) 42. (3)
10. (3) 21. (4) 32. (1) 43. (1)
11. (3) 22. (2) 33. (1) 44. (1)