Evaluation sheet NGDicleam % Name: a Date: Assignment: Performance: Hint to improve performance: ‘1 © Understand what the question CG Excellent wants G Very good D Study topic: C Average © Needs improvement O Use better sequencing of points PROGRESS: © Use more keywords C Improving O Take a look at marking scheme CG Same © Make sure your words are C Worse than last accurate Other Notes: Use of data in graph / table questions: (if found) Skill Good | Average | Needs Improvement Extracting data from graph/table Comparative data figures Data manipulation (calculations) i Scanned with CamScanner15 36 Whatis a difference between T-lymphocytes and B-lymphocytes in the immune system? T-ymphooytes B-lymphocytes R do not form plasma cells form plasma cells which secrete antibodies into the blood stream do not stimulate macrophages to | stimulate macrophages to carry out 8 carry out phagocytosis phagocytosis © | formed from cells in the thymus formed from bone marrow cells D produce memory cells do not produce memory cells 37 In an investigation into the immune response, a volunteer was exposed to two different antigens, X and Y. The relative antibody concentration in the blood was measured at regular intervals over 60 days. The graph shows the time when the volunteer was exposed to each antigen and the antibody concentration against time for antigens X and Y. antibody concentration /arbitrary units, antibody for antigen X antibody for antigen Y *f 5 10 15 20 apse 35 40 45 50 55 60 first exposure second exposure time /days to antigen X to antigen X first exposure to antigen Y What is the explanation for the results displayed on the graph? ‘A A primary and secondary immune response against antigen X occurred, with the memory B-lymphocytes inhibiting the secondary immune response against antigen Y. B_ A primary immune response to antigen Y occurred and memory B-lymphocytes specific to antigen Y enhanced the secondary immune response to antigen X. © Memory B-lymphocytes specific to antigen X enabled a secondary immune response to ‘occur; different B-lymphocytes were activated for a primary immune response for antigen Y. D Plasma cells remaining from the first exposure to antigen X undergo rapid clonal selection to produce high levels of antibody against antigen X and lower levels of antibody against antigen Y. Scanned with CamScanner38 Which row correctly describes B-lymphocytes? processed in release antibodies immediately after the.thyenus formation A v v B v x c x v D x x key Jv = correct X = incorrect 16 39 Which features of monoclonal antibodies are important to their use in the treatment of cancer? 1 They can bind to tumour-associated antigens. 2 They can distinguish between different strains of pathogens. 3 They can deliver drugs to specific targets. 1 9oOm > SESS 2 v x v x x SS Jo key is important X= is not important Scanned with CamScanner39 40 7 When a person is given a vaccination immunity to certain pathogens develops. Which of the effects of vaccination are correct? 1. production of antibodies to protect against future infections 2 results in artificial active immunity 3 stimulation of appropriate lymphocytes A 1,2and3 B 1and2only C 1and3only D 2and3only What is the first response by the immune system to a pathogen? ‘A ingestion of the pathogen by phagocytes B production of antibodies © production of antigens D stimulation of B memory cells Scanned with CamScanner40 Why are spleen cells fused with myeloma cells during monoclonal antibody production? A B c D so that the antibodies become specific for the necessary antigen s0 that the resulting hybridoma cells can reproduce indefinitely to allow antibodies that are not specific for the required antigen to be removed to increase the rate of production of antibodies produced by the hybridoma cells Scanned with CamScanner38 Where are antigens found? aeeess in blood plasma A v v key B wv x J/= antigens found c x v X= antigens not found D x x 39 The graph shows how the body reacts following exposure to an antigen for the first and second time. second exposure first concentration exposure of antibody time What is the direct cause of the increase in antibody production after the second exposure to antigens? A B-memory cells B_ macrophages © plasma cells D_ T-memory cells Scanned with CamScanner