5 Diseases Proven To Respond Better To

Cannabis Than Prescription Drugs

by MARCO TORRES

The reason cannabis is so effective medicinally is

directly related to its ability to interact with receptors in the body which inhibit inflammation and

prevent disease. Cannabis does this so well, that few drugs can compete with its level of potency

which come essentially with no side effects. These are just 5 diseases that are proven to respond

better to cannabis than to drugs, however, there are many studies currently being conducted

that may prove dozens more.

Many researchers have noted that there was “inadequate” data for decaded to determine

whether smoked marijuana was safe or effective in treating symptoms of pain and preventing

disese. The primary reason for the lack of data had to do with the National Institute on Drug

Abuse, or NIDA, which was the only source of cannabis for research and they were blocking the

most meaningful studies due to close ties with pharmaceutical companies.

This view was supported by Dr. David Bearman, the executive vice president for the Academy of

Cannabinoid Medicine/Society of Cannabis Clinicians. “Part of the problem in the United States is

that the NIDA has blocked almost all meaningful studies on cannabis,” Bearman said. Bearman
argues that while synthetic cannabis pills do offer pain relief, marijuana is cheaper, has fewer

side effects and can be more effective.

Now decades of propaganda is being reversed as scientists and the public are being exposed to

the true potential of cannabis and its ability to both heal and prevent disease.

Excellent cannabis strains which treat various medical conditions include Charlotte’s

Web, Harlequin, Sour Tsunami and Cannatonic.

Noting cannabis’ vastly superior side effect profile DEA Administrative Law Judge, Francis L.

Young, after a two-year hearing to reschedule cannabis in 1998 said:

“Nearly all medicines have toxic, potentially lethal effects. But marijuana is not such a substance.

There is no record in the extensive medical literature describing a proven, documented cannabis-

induced fatality… In strict medical terms marijuana is far safer than many foods we commonly

consume … Marijuana, in its natural form, is one of the

safest therapeutically active substances known to man.”

5 DISEASES PROVEN TO RESPOND BETTER TO

Cannabinoids, the active components of marijuana, inhibit tumor growth and also kill cancer

cells. Tetrahydrocannabinol (THC), the principal psychoactive constituent (or cannabinoid) of the

cannabis plant, targets cannabinoid receptors similar in function to endocannabinoids, which are

cannabinoids that are naturally produced in the body and activate these receptors.
Researchers have now found that cannabidiol has the ability to ‘switch off’ the gene responsible

for metastasis in an aggressive form of cancer. Importantly, this substance does not produce the

psychoactive properties of the cannabis plant.

A Spanish team, led by Dr Manuel Guzmon, wanted to see whether they could prevent a form of

cancer (glioblastoma multiforme) from growing by cutting off its blood supply. Glioblastoma

multiforme is one of the most difficult cancers to treat – it seldom responds to any medical

intervention, especially conventional methods which poisoning and primatively destroy cells such

as radiotherapy, chemotherapy and surgery.

Genes associated with blood vessel growth in tumors through the production of a chemical called

vascular endothelial growth factor (VEGF) have their activity reduced when exposed to

cannabinoids.

Cannabinoids halt VEGF production by producing Ceramide. Ceramide controls cell death.

Dr Manuel Guzmon tested a cannabinoid solution of patients had glioblastoma multiforme and

had not responded to chemotherapy, radiotherapy or surgery. The scientists took samples from

them before and after treating them with a cannabinoids solution – this was administered directly

into the tumor.

Amazingly, both patients experienced reduced VEGF levels in the tumor as a result of treatment

with cannabinoids.

A study published in the July 2002 edition of the medical journal Blood, which found that THC

and some other cannabinoids produced “programmed cell death” in different varieties of human
leukemia and lymphoma cell lines, thereby destroying the cancerous cells but leaving other cells

unharmed.

A study published in a 1975 edition of the Journal of the National Cancer Institute, which showed

that THC slowed the growth of lung cancer, breast cancer and virus-induced leukemia in rats.

Titled Antineoplastic activity of cannabinoids, this study was funded by the US National Institute

of Health, and performed by researchers at the Medical College of Virginia. Despite the promising

results, no further research was made, and the study has essentially disappeared from the

scientific literature.

A 1994 study, which documented that THC may protect against malignant cancers, and which

was buried by the US government. The $2 million study, funded by the US Department of Health

and Human Services, sought to show that large doses of THC produced cancer in rats. Instead,

researchers found that massive doses of THC had a positive effect, actually slowing the growth of

stomach cancers. The rats given THC lived longer than their non-exposed counterparts.

he study was unpublished and the results hidden for almost three years, until it was finally leaked

to the media in 1997. (CC#17, THC for tumors).

2. Fibromyalgia (FM)

More and more patients with FM are finding effective relief from cannabis.

So say the results of a recent online survey of over 1,300 subjects conducted by The National

Pain Foundation and NationalPainReport.com. Among those surveyed, 379 subjects said that they

had used cannabis therapeutically. Sixty-two percent of them rated the substance to be “very

effective” in the treatment of their condition.

rated the drug as “very effective,” and 60 percent said it did “not work at all.” Among those who

had used Lyrica (Pregabalin), ten percent said that drug was “very effective,” versus 61 percent

who reported no relief. Among those who had used Savella (Milnacipran), ten percent rated the

drug as effective, and 68 percent said it was ineffective.

Commenting on the survey results, Dr. Mark Ware — associate professor in family medicine and

anesthesia at McGill University in Montreal — told the National Pain Report, “We desperately

need someone to step up and explore this potential for the efficacy of cannabis.”

Ware, whose own clinical research has demonstrated inhaled pot’s efficacy in subjects with hard-

to-treat refractory pain, added: “The scientific rationale is there. There are some early

preliminary, proof-of-concept clinical trials that demonstrate cannabis may be effective. Now your

study adds additional weight that patients are reporting that cannabis may be better than the

existing therapies. I think that this really should provide incentives for researchers to take a hard

look at clinical trials to really explore that in much more detail.”

Some investigators already have. In 2006, German scientists reported that the administration of

oral THC significantly reduced both chronic and experimentally induced pain in patients with

fibromyalgia. Subjects in the trial were administered daily doses of 2.5 to 15 mg of THC, but

received no other pain medication during the study. Among those participants who completed the

trial, all reported significant reductions in daily pain and electronically induced pain.

More recently, Spanish researchers assessed the use of cannabis treatment of Fibromyalgia. A

cursory review of the results indicates why so many FM patients are preferring pot over pills.
Investigators reported, “The use of cannabis was associated with beneficial effects on some FM

symptoms. … After two hours of cannabis use, VAS (visual analogue scales) scores showed a

statistically significant reduction of pain and stiffness, enhancement of relaxation, and an

increase in somnolence and feeling of well being.”

3. Epilepsy

By far the most common approach to treating epilepsy is to prescribe antiepileptic drugs.

Commonly prescribed drugs include clonazepam, phenobarbital, and primidone. Some relatively

new epilepsy drugs includetiagabine, gabapentin, topiramate, levetiracetam, and felbamate.

Many medications amplify side effects such as fatigue and decreased appetite. Epilepsy

medication also may predispose people to developing depression or psychoses.

Several lines of evidence now suggest that cannabinoid compounds are anticonvulsant and

empirical evidence in many children is establishing conclusive evidence that cannabinoid therapy

may be the most effective treatment available for epileptics.

In “The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model

of Temporal Lobe Epilepsy”, Robyn Wallace explained that the data not only shows the

anticonvulsant activity of exogenously applied cannabinoids but also suggests that endogenous

cannabinoid tone modulates seizure termination and duration through activation of the CB1

receptor. By demonstrating a role for the endogenous cannabinoid system in regulating seizure

activity, these studies define a role for the endogenous cannabinoid system in modulating

neuroexcitation. The endogenous cannabinoid system thus provides on-demand protection

against acute excitotoxicity in central nervous system neurons.

Anti-convulsant drugs have potentially serious side-effects, including bone softening, reduced

production of red blood cells, swelling of the gums, and emotional disturbances. Other occasional

effects include uncontrollable rapid eye movements, loss of motor co-ordination, coma and even
death. In addition, these medications are far from ideal in that they only completely stop seizures

in about 60% of patients.

Large amounts of anecdotal reports and patient case studies indicate the assistance of cannabis

in controlling seizures. Cannabis analogues have been shown to prevent seizures. Patients report

that they can wean themselves off prescription drugs, and still not experience seizures if they

have a regular supply of cannabis.

The British company, GW Pharmaceuticals pursued advanced clinical trials for the world’s first

pharmaceutical developed from raw marijuana instead of synthetic equivalents. In response to

urgent need expressed by parents of children with intractable epilepsy, the U.S. Food and Drug

Administration is now allowing Investigational studies of purified CBD (cannabidiol) for seizures.

Ben Whalley and colleagues at the Center for Integrative Neuroscience and Neurodynamics,

University of Reading, using mouse models of epilepsy, established safety and showed that CBD

and another cannabinoid, CBDV, exert anti-seizure and anti-inflammatory effects. This

research came to the attention of families in the US who had loved ones with epilepsy.

The British Medical Association has stated that cannabis may prove useful as an ‘adjunctive

therapy’ for patients who cannot be kept satisfactorily free of seizures on current medications.

Likewise, the National Institutes of Health workshop considered that this is ‘an area of potential

value’, based largely on animal research showing anticonvulsant effects.

Charlotte’s Web is a sativa marijuana strain that has gained popularity as a good option for

treating seizures as well as a range of other medical conditions. This medical potency is due to its

high-CBD content, which was specifically cultivated by Colorado breeders The Stanley Brothers

for a young epileptic patient named Charlotte. This strain is effective with little to no psychoactive

effects, making it great for those who don’t want their medication to affect their daily tasks.
4. Multiple Sclerosis

The U.S. Food and Drug Administration (FDA) has alerted the public that patients diagnosed with

multiple sclerosis (MS) have developed serious brain infections after taking the drug Gilenya

(fingolimod).

Other drugs like Tysabri are antibody treatments designed to block certain white blood cells that

cause MS when they attack nerves. the problem is they have a history of also making patients

vulnerable to infection. Biogen and Elan yanked theirs off the market after two cases of the brain

disease were confirmed among patients taking the drug; a month later, a third case was

confirmed. The FDA allowed the drug to return to the market in July 2006 after they stated

benefits outweighed the risks, no doubt with some help from Big Pharma.

GW received government approval in 1998 to develop cannabis-based plant extracts. Their

flagship product Sativex is a highly defined extract containing an approximately 50-50 mix of CBD

and THC that has been approved by regulators in the UK and more than 20 other countries for

treating pain and spasticity in Multiple Sclerosis.

Some forms of medical marijuana are proven to alleviate certain symptoms in patients with

multiple sclerosis (MS), according to guidelines published in the journal Neurology.

In a review of 2,608 studies, the researchers were able to assess which therapies had sufficient

evidence to indicate that they may be effective for patients with MS. Overall, researchers

discovered that certain forms of medical marijuana — a spray form and a pill form — appeared to

have the most evidence indicating they may be helpful in patients with MS.
“What we learned are these specific forms of medical marijuana can ease patients’ symptoms —

specific symptoms of spasticity, or muscle stiffness … and helped with frequent

urination,”according to study author Dr. Pushpa Narayanaswami.

In a 2011 study, Israeli researchers showed that CBD helps treat MS-like symptomsby preventing

immune cells from transforming and attacking the insulating covers of nerve cells in the spinal

cord. After inducing an MS-like condition in mice — partially paralyzing their limbs — the

researchers injected them with CBD. The mice responded by regaining movement, first twitching

their tails and then beginning to walk without a limp. The researchers noted that the mice

treated with CBD had much less inflammation in the spinal cord than their untreated

counterparts.

In another study in Neuroscience researchers used experimental autoimmune encephalomyelitis

(EAE), an animal model of MS, and found that cannabinoids reduced microglia activation,

nitrotyrosine formation, T cell infiltration, oligodendrocyte toxicity, myelin loss and axonal

damage in the mouse spinal cord white matter and alleviated the clinical scores when given

either before or after disease onset.

5. ADHD/ADD

The normal course of treatment for a child diagnosed with ADD/ADHD, is a course of

methylphenidate, better known as Ritalin. For the child diagnosed with ADD/ADHD, the side

effects of using Ritalin, are many, including psychosis (abnormal thinking or hallucinations),

difficulty sleeping, stomach aches, diarrhea, headaches, lack of hunger (leading to weight loss)

and dry mouth. In some cases, the use of Ritalin has led to death. Death can be caused due to

burst blood vessels, heart failure and fever. Violence is a leading cause of amphetamine-related

deaths. Violent tendencies can develop after even regular use.

documentary Generation Rx, details the disturbing and ongoing chemical abuse of children by

conventional medicine. The prescription of psychiatric drugs to the masses, specifically children,

are altering their minds, bodies and entire lives.

While some apply preconceptions that marijuana exacerbates ADHD almost all California

cannabinologists believe cannabis and cannabinoids have substantially improved the lives of

ADHD sufferers, and with less negative side effects than common stimulant drug ADHD

treatments.

We have come to understand more about the brain and the role of dopamine and the

endocannabinoid system we are starting to unravel how cannabis, anandamide and dranabinol

act to free up dopamine and decrease the overstimulation of the midbrain.

The results in treating ADHD with cannabis are often spectacular. Patients report grades going

from Cs and Ds to As and Bs. Dr. David Bearman, a physician practicing in Santa Barbara,

California, reports patients have said, “I graduated from the Maritime Academy because I smoked

marijuana,” and “I got my Ph.D. because of smoking marijuana.” Almost universally, ADHD

patients who therapeutically used cannabis reported in helped them pay attention in lecture,

focus their attention instead of thinking of several ideas almost at the same time, helped them to

stay on task and do their homework.

70 percent of the brain’s job is to inhibit sensory input from the other 30 percent. Typical ADHD

symptoms include distractability. The most accepted theory about ADHD rests on the fact that

about 70% of the brain’s function is to regulate input to the other 30%. The cause of ADHD is

probably a decreased ability to suppress sensory input both internal and external input (need a

reference here). Basically the brain is overwhelmed with too much information that comes too
fast. In ADHD, the brain is cluttered with and too aware of all the nuances of a person’s daily

experience. This phenomenon is caused by a dopamine dysfunction.

Since the endocannabinoid system was discovered, many studies revealed that marijuana also

modulates the dopamine system and therefore has a potential for ADHD treatment. As recounted

in the physicians’ stories below, marijuana may be a safer, less costly, and more effective

treatment than anything available from the pharmaceutical companies.

Dr. Claudia Jensen, a 49-year old California pediatrician and mother of 2 teenage daughters, says

marijuana might be the best treatment for ADHD. In an interview with the FOD news network,

she said:

“Why would anyone want to give their child an expensive pill… with unacceptable side effects,

when he or she could just go into the backyard, pick a few leaves off a plant and make tea…?”

“Cannabinoids are a very viable alternative to treating adolescents with ADD and ADHD … I have

a lot of adult patients who swear by it.”

In her testimony, before the House Committee on Government Reform on Marijuana (2004) Dr.

Jensen discussed the practice of recommending marijuana to patients with ADHD in an 11-page

statement. Her testimony summarized hundreds of published scientific articles on the

safety/efficacy of marijuana that have produced strong scientific evidence that marijuana is an

important medicine.

Her reasons for looking to marijuana as treatment for ADHD?

“The other legal drugs used to treat ADD are helpful in many patients, but they all have side

effects… the other five of the nine drugs used to treat ADD in this country haven’t even been

scientifically tested … for ADD in children. These are drugs for depression and high blood
pressure …Of all the drugs use to treat ADD, cannabis has the least number of serious side

effects.

Her explanation for why marijuana is opposed by the pharmaceutical companies:

“The real problem with allowing patients to use cannabis as a medication is economics … If

cannabis were approved for use in just the ADD/ADHD market alone, it could significantly impact

the $1 billion a year sales for traditional ADD/ADHD pharmaceuticals.”

Sources:

cancerresearchuk.org

leafly.com

preventdisease.com

davidbearmanmd.com

ms-uk.org

medicalmarijuana.com

alternet.org

sciencedaily.com
http://www.realfarmacy.com/5-diseases-proven-to-respond-better-to-cannabis-than-
prescription-drugs/