Brand Generic Name Dosage/route Pharmacologic Therapeutic Mechanism of Indication Contraindication Side effect Adverse effect Nursing imp

name class class action

1.Toradol Ketorolac Adults NSAIDs Anti- May inhibit Short term Contraindicated in Abdominal or CNS: headache, Watch for a
younger than Inflammatory prostaglandin management of patients stomach pain dizziness, immediatel
age 65 and Drugs synthesis to moderately hypersensitive to (mild or drowsiness evaluate sig
adolescents produce anti- severe, acute ketorolac or aspirin moderate) CV: edema, symptoms o
age 17 and inflammatory, pain for single- or other NSAIDs. bruising at place HTNEENT: tinnitus (chest pain,
older: 60 mg analgesic, and dose treatment Hypersensitivity of injection. Nasal spray only: shortness o
or 30 mg IV antipyretic effects reactions, ranging diarrhea. increased or trouble
Adults age 65 from bronchospasm dizziness. lacrimation, nasal breathing) o
and older, to anaphylactic drowsiness. discomfort, stroke (wea
patients shock, have headache. rhinalgia, rhinitis, one part or
weighing less occurred and indigestion. throat irritation the body, sl
than 50kg: 30 appropriate nausea. GI: abdominal pain, speech).Car
mg IM or 15 counteractive dyspepsia, observe pati
mg IV measures must be heartburn, nausea, with
available when first constipation, coagulopat
dose of ketorolac diarrhea, those takin
injection is given flatulence, GI anticoagula
Contraindicated in fullness, GI Drug inhibit
children younger perforation, peptic platelet
than age 17, as ulceration, aggregation
prophylactic stomatitis, can prolong
analgesic before vomiting, GI bleeding tim
major surgery, and hemorrhage NSAIDs may
intraoperatively increase the
when hemostasis is serious thro
critical; in patients events, MI,
with advanced renal stroke, whic
impairment; and in be fatal. Th
those at risk for may be gre
renal failure from with longer
volume depletion in patients
disease or r
 factors for C
disease.
2,Diamox Acetazolamide Adult: 250 mg Carbonic Diuretics Promotes renal Chronic open – Contraindicated in Burning, CNS: seizures, Monitor flu
to 1g PO anhydrase excretion of angle glaucoma patients crawling, itching, drowsiness, intake and
inhibitors sodium, potassium, hypersensitive to numbness, paresthesia, glucose, an
bicarbonate, and drug and in those prickling, "pins confusion, electrolytes
water. As with hyponatremia and needles", or depression, ataxia, especially
anticonvulsant, or hypokalemia, tingling feelings. headache, malaise, potassium,
drug normalizes marked renal or changes in fever, fatigue, bicarbonate
neuronal hepatic disease or vision. excitement, chloride. W
discharge. In dysfunction, continuing dizziness, flaccid drug is used
mountain sickness, suprarenal gland ringing or paralysis, taste diuretic the
drug stimulates failure, buzzing or other alteration consult pre
ventilation and hyperchloremic unexplained CV: flushing and dietitia
increases cerebral acidosis, or cirrhosis. noise in the ears. EENT: transient providing a
blood flow. In Contraindicated in hearing loss. myopia, hearing potassium d
glaucoma, drug patients receiving increased dysfunction, Monitor old
reduces IOP. long-term treatment sensitivity of skin tinnitus adults close
for chronic to sunlight. GI: nausea, because the
noncongestive redness or other vomiting, anorexia, especially
angle-closure discoloration of diarrhea, melena, susceptible
glaucoma. the skin. constipation excessive d
severe sunburn. GU: polyuria, Weigh patie
hematuria, daily. Rapid
crystalluria, excessive fl
glycosuria, renal may cause w
calculus loss and
Hematologic: hypotensio
aplastic anemia,
leukopenia,
thrombocytopenia
purpura, hemolytic
anemia,
agranulocytosis,
 pancytopenia

3.Tylenol Acetaminophen Adult: 325 to Para- Analgesics Thought to Mild pain or Contraindicated in Skin rash, CNS: agitation (IV), Many OTC a
650 mg PO aminophenol produce analgesia fever patients hypersensitivity anxiety, fatigue, prescription
Children: 430 derivatives by inhibiting hypersensitive to reactions. headache, products co
to 500 mg PO prostaglandin and drug. IV form is Nephrotoxicity insomnia, fever acetaminop
other substances contraindicated in (elevations in CV: HTN, aware of th
that sensitize pain patients with severe BUN, creatinine) hypotension, calculating
receptors. Drug hepatic impairment Hematological: peripheral edema, daily dose.
may relieve fever or severe active liver anemia, periorbital edema, Consider re
through central disease. leukopenia, tachycardia (IV)GI: total daily d
action in the neutropenia, nausea, vomiting, increasing d
hypothalamic heat- pancytopenia. abdominal pain, intervals in
regulating center. Metabolic and diarrhea, with hepati
electrolyte. constipation (IV) renal impai
Decreased serum
bicarbonate.
4.Dilaudid Hydromorphone Adult: 1 to 4 Opioids Opioid Binds with opioid Management of Contraindicated in constipation. CNS: sedation, Reassess pa
mg PO analgesics receptors in the pain severe patients headache or somnolence, level of pain
CNS, altering enough to hypersensitive to dizziness. dizziness, euphoria, least 15 and
perception of and require opioid drug; in those with fatigue or light-headedness, minutes aft
emotional treatment and intracranial lesions drowsiness insomnia, drug administrati
response to pain. for which that cause increased (especially right withdrawal For better a
Also suppresses alternative ICP; in those with after a dose) syndrome effect for ch
the cough reflex by treatment paralytic ileus or loss of appetite, (extended-release pain, give d
direct action on the options are narrowed or nausea and form), headache, regularly sc
cough center in the inadequate obstructed GI tract; vomiting. confusion, syncope, intervals, be
medulla. for obstetric dysgeusia patient has
analgesia; and in CV: cardiac arrest, pain.
those with hypotension, HTN, Routinely m
depressed flushing, all patients
ventilation, such as bradycardia, signs and
in status extrasystoles, symptoms o
asthmaticus, COPD, palpitations, chest misuse, abu
 cor pulmonale, discomfort, edema, addiction d
emphysema, and tachycardia treatment.
kyphoscoliosis. Monitor pa
for respirat
depression,
especially w
first 24 to 7
of drug initi
and after do
increase. Se
life-threate
fatal respira
depression
occur.
5.Strattera Atomoxetine Adult: 40 mg Selective ADHD Drug May be related to ADHD Contraindicated in heartburn. orthostatic Use drug as
PO norepinephrine selective inhibitor patients nausea. hypotension, a total treat
Children: 0.5 reuptake of the presynaptic hypersensitive to vomiting. tachycardia, HTN, program fo
mg/kg PO inhibitors norepinephrine drug or its loss of appetite. palpitations, hot including
transporter components; in weight loss. flush psychologic
those with current constipation. EENT: mydriasis, educationa
or history of stomach pain. conjunctivitis, dry social interv
pheochromocytoma, gas. mouth, Drug may b
or narrow-angle oropharyngeal discontinue
glaucoma; in those pain, without tap
with serious CV pharyngolaryngeal Periodically
disorders who are pain, sinus monitor pa
intolerant of headache for changes
increased BP or HR; or BP.
and in those who Assess patie
have taken an MAO carefully fo
inhibitor within the disease, inc
past 2 weeks. family histo
sudden dea
ventricular
 arrhythmia
Evaluate pa
with new ca
symptoms
promptly.
6.Selenor Doxepin Adult: 75 mg TCAs Antidepressants Increases amount Depression; Contraindicated in dizziness drowsiness, Don't withd
PO of norepinephrine, anxiety patients increase in pupil dizziness, seizures, drug abrup
serotonin, or both hypersensitive to size confusion, gradually ta
in the CNS by drug and in those dry mouth numbness, dosage to m
blocking their with glaucoma or mouth sores hallucinations, withdrawal
reuptake by the tendency toward skin more paresthesia, ataxia, symptoms.
presynaptic urine retention and sensitive to weakness, Monitor pa
neurons during acute sunlight than headache, nausea, hea
recovery phase of an usual extrapyramidal and malaise
MI. flushing reactions, tardive abrupt with
changes in dyskinesia, tremor, of long-term
appetite or taste disturbance, therapy; th
weight fatigue symptoms d
changes in the CV: orthostatic indicate add
way things taste hypotension, HTN, Enter
indigestion tachycardia, ECG If signs or
constipation changes, flushing symptoms o
psychosis o
increase, ex
prescriber t
reduce dosa
Record moo
changes. M
patient for
suicidality,
allow only a
minimum s
drug.
If using dru
 insomnia an
symptoms d
resolve afte
days, evalu
primary psy
or medical

7.Lioresal Baclofen Adult and Gamma- Skeletal muscle Hyperpolarizes Spasticity in MS: Contraindicated in Feeling sleepy, CV: hypotension, Don't use o
children: 5mg aminobutyric relaxant fibers to reduce spinal cord patients tired, dizzy or peripheral edema to treat mu
PO t.i.d acid impulse injury hypersensitive to weak EENT: amblyopia, spasm caus
transmission. drug. Feeling or being nasal congestion, rheumatic
Appears to reduce sick (nausea or dry mouth, disorders, c
transmission of vomiting) excessive salivation palsy, Parki
impulses from the Diarrhoea GI: nausea, disease, or
spinal cord to Headaches. constipation, because dru
skeletal muscle, Problems diarrhea, vomiting effectivene
thus decreasing the sleeping GU: urinary these indica
frequency and Dry mouth frequency, urine hasn't been
amplitude of Rapid eye retention, erectile established
muscle spasms in movements, dysfunction, Life-threate
patients with spinal blurred vision or incontinence CNS depres
cord lesions. difficulty Metabolic: collapse, an
focusing hyperglycemia, respiratory
Excessive weight gain may occur w
sweating or a intrathecal
mild rash. Have traine
and resusci
equipment
available du
screening, d
titration, an
refill.
8.Lodine Etodolac Adult: 200 to NSAIDs Anti- The analgesic Acute pain patients with known Bloated, full particularly erosion To reduce a
400 mg PO inflammatory effect of NSAIDs hypersensitivity to feeling. of the gastric gastrointes
 drugs may result from etodolac or other continuing mucosa. The most effects, adm
interference with ingredients in ringing or common symptoms NSAIDs with
the prostaglandins etodolac tablets. buzzing or other are abdominal or milk. If th
involved in pain. Etodolac tablets unexplained pain, dyspepsia, patient has
Prostaglandins should not be given noise in ears. epigastric distress, history of a
appear to sensitize to patients who excess air or gas heartburn, and inform the
pain receptors to have experienced in stomach or nausea. prescriber.
mechanical asthma, urticaria, or intestines. the prescrib
stimulation or to other allergic-type hearing loss. drug is ineff
other chemical reactions after lack or loss of If renal or h
mediators. NSAIDs taking aspirin or strength. abnormaliti
inhibit synthesis of other NSAIDs passing gas. occur, stop
prostaglandins sneezing. drug and no
peripherally and stuffy nose. prescriber
possibly centrally.
9.Dilantin Phenytoin Adult: Loading Hydantoin Anticonvulsants May stabilize Generalized Contraindicated in Headaches. CV: bradycardia, Carefully m
dose of 10 to derivatives neuronal tonic-clonic patients Make sure you periarteritis cardiac stat
15 mg/kg IV membranes and status hypersensitive to rest and drink nodosa, during and
limit seizure epilepticus; hydantoins and in plenty of fluids hypotension, CV administrati
activity either by prevention and those with a history Feeling drowsy, arrest toxicity may
increasing efflux or treatment of of prior acute sleepy or dizzy. EENT: diplopia, increase wi
decreasing influx of seizures during hepatotoxicity As your body nystagmus, blurred infusion rat
sodium ions across neurosurgery attributable to gets used to vision, gingival above those
cell membranes in phenytoin. phenytoin, these hyperplasia recommend
the motor cortex Parenteral side effects GI: nausea, Toxicity has
during generation phenytoin is also should wear off vomiting, been repor
of nerve impulses. contraindicated in Feeling nervous, constipation below the
patients with sinus unsteady or Hematologic: recommend
bradycardia, SA shaky agranulocytosis, infusion rat
block, second- or Feeling or being leukopenia, Reduction i
third-degree AV sick (nausea or pancytopenia, administrati
block, or Adams- vomiting) thrombocytopenia, or discontin
Stokes syndrome. Constipation macrocythemia, of dosing m
Sore or swollen megaloblastic needed Mo
 gums. anemia patient for
hypersensiti
reactions, in
angioedem
Don't stop d
suddenly be
this may wo
seizures. Ca
prescriber
immediatel
adverse rea
develop.
10.Topamax Topiramate Adult and Sulfamate- Anticonvulsants May block sodium To prevent Contraindicated in Tiredness, CV: chest pain, Monitor pa
children: 25 substituted channel and migraine and patients drowsiness, flushing cognitive an
mg PO monosaccharides potentiate the headache hypersensitive to dizziness, loss of EENT: abnormal neuropsych
activity GABA while drug or its coordination, vision, diplopia, adverse rea
inhibiting components. tingling of the nystagmus, including be
glutamate and Use cautiously in hands/feet, loss conjunctivitis, disturbance
carbonic anhydrase patients with of appetite, bad secondary angle- somnolence
hepatic and renal taste in your closure glaucoma, fatigue, con
impairment. mouth, diarrhea, epistaxis, psychomot
Bioequivalence and weight loss pharyngitis, slowing, or
hasn't been sinusitis, rhinitis, difficulty wi
demonstrated dry mouth, concentrati
between Trokendi increased salivation memory, sp
XR and Qudexy XR. GI: anorexia, or language
nausea, abdominal If needed,
pain, constipation, withdraw
diarrhea, anticonvuls
dyspepsia, (including
gastroenteritis, topiramate
gingivitis, vomiting, gradually to
gastritis minimize ri
increased s
 activity.
Monitoring
topiramate
isn't necess
11.Rayos Prednisone Adult: 200 mg Adrenocorticoids Corticosteroid Decreases Acute Contraindicated in Weight gain GU: menstrual Determine
PO inflammation, exacerbations of patients Indigestion irregularities, patient is
mainly by MS (immediate- hypersensitive to Problems increased urine hypersensiti
stabilizing release) drug or its sleeping calcium level other
leukocyte components; in (insomnia) Hematologic: corticostero
lysosomal those with systemic Feeling restless anemia, Immediate-
membranes; fungal infections Sweating a lot neutropenia drug may b
suppresses (immediate-release Mild mood Hepatic: for alternat
immune response; only), cerebral changes hepatomegaly therapy.
stimulates bone malaria, or active Always adju
marrow; and ocular herpes lowest effec
influences protein, simplex; and in dose.
fat, and those receiving Most adver
carbohydrate immunosuppressive reactions to
metabolism. doses together with corticostero
live-virus vaccines. dose- or du
dependent.
For better r
and less tox
give a once
dose in the
morning.
Monitor BP
patterns, an
potassium l
12.Tapazole Methimazole Adult: 15 mg Thyroid hormone Antihyperthyroid Inhibits synthesis Hyperthyroidism Contraindicated in Black, tarry CV: edema Monitor CB
PO antagonists drug of thyroid hormone patients stools. GI: nausea, periodically
Children: 0.4 hypersensitive to bleeding gums. vomiting, salivary detect impe
mg/kg/day PO drug and in those bleeding under gland enlargement, leukopenia,
with history of acute the skin. epigastric distress thrombocyt
 pancreatitis after bloody or cloudy Hematologic: aplastic ane
methimazole use. urine. agranulocytosis, and
burning, leukopenia, agranulocyt
crawling, itching, thrombocytopenia, also monito
numbness, aplastic anemia hepatic fun
prickling, "pins Hepatic: jaundice, Stop drug if
and needles", or hepatic abnormality
tingling feelings. dysfunction, Drug may in
chills. hepatitis risk of
difficulty in agranulocyt
breathing. which can b
dizziness or threatening
lightheadedness. Monitor pa
sore throat
and genera
malaise and
symptoms
promptly.
Monitor PT
especially b
invasive
procedures
13.Revatio Sildenafil Adult: 5 or 20 PDE5 Inhibitors Erectile When used for To improve Contraindicated in Headaches CNS: headache, The serious
mg PO Dysfunction erectile exercise ability patients Feeling sick seizures, anxiety, events linke
Drugs dysfunction, drug and delay hypersensitive to (nausea) dizziness, insomnia, this drug's u
increases effect of clinical drug or its Flushing somnolence, erectile dys
nitric oxide by worsening in components. including hot paresthesia, fever mainly invo
inhibiting PDE5. patients with flushes CV: flushing patients wit
When sexual WHO group 1 Indigestion dyspepsia, underlying
stimulation causes PAH Stuffy nose diarrhea, gastritis, disease who
local release of Feeling dizzy nausea increased ri
nitric oxide, GU: UTI cardiac effe
inhibition of PDE5 Musculoskeletal: related to s
by sildenafil causes back pain, myalgia activity.
 increased levels of Respiratory: Patients wit
cyclic guanosine dyspnea caused by
monophosphate connective
(cGMP) in the disease are
corpus prone to ep
cavernosum, during ther
resulting in smooth than those
muscle relaxation primary pul
and inflow of blood HTN.
to the corpus
cavernosum. In
PAH, drug
increases cGMP
level by preventing
its breakdown by
phosphodiesterase,
prolonging smooth
muscle relaxation
of the pulmonary
vasculature, which
leads to
vasodilation.
14.Estrace Estradiol Women: q to Estrogen Estrogen Increases synthesis Vasomotor Contraindicated in headache. Hepatic: cholestatic Ensure that
2 mg PO of DNA, RNA, and menopausal patients with active breast pain or jaundice has physica
protein in symptoms, or history of tenderness. Metabolic: weight before starti
responsive tissues; female thrombophlebitis or nausea. gain, therapy. Pa
reduces release of hypogonadism, thromboembolic vomiting. hypothyroidism, receiving lo
FSH and LH from female disorders, estrogen- constipation. hypercalcemia (in therapy sho
the pituitary gland. castration, dependent gas. patients with have yearly
primary ovarian neoplasia, breast or heartburn. breast cancer and Monitor lip
failure reproductive organ weight gain or bone metastases) BP, body w
cancer, or loss. Musculoskeletal: and hepatic
undiagnosed arthralgia, back function. Pr
abnormal genital pain, myalgia, neck should asse
 bleeding. pain, limb pain, patient's ne
Contraindicated in fractures continue es
patients with Respiratory: URI, therapy. Ma
protein C, protein S, asthma attempts to
or antithrombin exacerbation, taper at 3- t
deficiency or other bronchitis month inte
known
thrombophilic
disorders.
15.Lanoxin Digoxin Adult and Cardiac inotropes Inhibits sodium- Heart failure, Contraindicated in Feeling dizzy CNS: confusion, Drug-induce
Children older glycosides potassium– rapid patients Feeling or being weakness, mental arrhythmia
than age 10: activated digitalization hypersensitive to sick disturbances increase the
10 to 15 mcg/ adenosine drug and in those Diarrhoea (anxiety, severity of H
kg PO triphosphatase, with digitalis- Changes in your hallucinations, hypotensio
Children ages promoting induced toxicity, vision depression, children, ca
5 to 10: 20 to movement of ventricular Skin rashes delirium), dizziness, arrhythmia
45 mcg/kg PO calcium from fibrillation, or headache including si
extracellular to ventricular CV: arrhythmias, bradycardia
intracellular tachycardia unless heart block usually earl
cytoplasm and caused by HF. EENT: blurred of toxicity.P
strengthening vision, diplopia, with
myocardial light flashes, hypothyroid
contraction. Also photophobia, extremely s
acts on CNS to yellow-green color to cardiac
enhance vagal disturbance, halos glycosides a
tone, slowing around visual need lower
conduction images Enter
through the SA and Monitor po
AV nodes. level carefu
corrective a
before
hypokalemi
occurs.
Hyperkalem
 result from
toxicity.

16.Norvasc Amlodipine Adult: 5 mg Calcium channel Antihypertensive Inhibits calcium ion hypertension Contraindicated in Headaches CNS: headache, Monitor pa
PO blockers influx across patients Feeling dizzy somnolence, carefully. So
Children ages cardiac and hypersensitive to Flushing fatigue, dizziness, patients, es
6 to 17: 2,5 to smooth-muscle drug. A pounding asthenia those with
5 mg PO cells, dilates heartbeat CV: edema, obstructive
coronary arteries Swollen ankles flushing, have develo
and arterioles, and palpitations increased
decreases BP and GI: nausea, frequency,
myocardial oxygen abdominal pain duration, or
demand. GU: sexual severity of a
dysfunction or acute MI
Musculoskeletal: initiation of
cramps channel blo
Respiratory: therapy or a
dyspnea of dosage in
Skin: pruritus, rash Monitor BP
frequently d
initiation of
therapy. Be
drug-induce
vasodilation
gradual ons
acute hypo
is rare.
17.Serevent Salmeterol Adult: 1 Long acting Bronchodilators Selectively COPD, Contraindicated in urticaria, rash, CV: tachycardia, Drug isn't in
diskus inhalation ( 50 selective beta^2 activates beta2 emphysema or patients angioedema, palpitations, HTN, for acute
mcg) agonist receptors, which chronic hypersensitive to bronchospasm, edema bronchospa
results in bronchitis drug, its ingredients, headache, EENT: Alert: Moni
bronchodilation; or milk proteins. tremor, or conjunctivitis, patient for
also, blocks the Contraindicated as anaphylaxis keratitis, nasal urticaria, w
release of allergic the primary congestion, may signal
 mediators from treatment for acute sinusitis, rhinitis, hypersensiti
mast cells lining episodes of asthma pharyngitis, reaction.
the respiratory or COPD. candidiasis of Monitor pa
tract. Contraindicated for mouth or throat, hypokalemi
treatment of asthma hyposalivation, hyperglycem
without an ICS. throat irritation,
Using without an ICS dental discomfort,
may increase the tracheitis
risk of asthma- GI: nausea,
related death. vomiting, dyspepsia
Metabolic:
hyperglycemia
18.Zyrtec Cetirizine Adult and Piperazine Antihistamines Cetirizine, a human Seasonal allergic headaches. contraindicated drowsiness and Patients tak
children 6 and derivatives metabolite of rhinitis dry mouth. in those patients impaired motor cetirizine re
older: 5 to 1o hydroxyzine, is an feeling sick (nausea) with a known function early in monitoring
mg PO antihistamine; its feeling dizzy. hypersensitivity therapy. They also relief of sym
Children 2 to principal effects diarrhoea. to it or any of its can cause blurred Healthcare
5: 2.5 mg PO are mediated via sore throat. ingredients or vision, members sh
selective inhibition sneezing or blocked hydroxyzine. constipation, and also monito
of peripheral H1 and runny nose. dry mouth and patients for
receptors. The throat. Some adverse eff
antihistaminic antihistamines, such as fati
activity of cetirizine such as somnolence
has been clearly promethazine, may adults and
documented in a cause cholestatic headaches
variety of animal jaundice, which children
and human models may be a
hypersensitivity
reaction, and may
predispose patients
to photosensitivity.
Promethazine may
also cause
extrapyramidal
reactions with high
doses