Hotel Name: Drugs Treating Inflammation

Drug Class/Ending Drug Name Action/Treats Misc./Adverse Effects/Teaching

- -

A: decreases inhibition of Bleeding/GI Bleed Hold pressure

prostaglandins GI Upset/Nausea Drug holiday 7
T: pain, fever, inflammation, days = 1 week if
Salicylate Aspirin decreases risk of TIA/stroke having surgery
NOT RECOM. for
*platelet aggregate: makes Toxicity
kids= Reyes
fibrinogen less sticky (not clot up) Tinnitus
Syndrome

GI Bleed Blackbox warning

A: blocks Cox 1 & Cox 2
DONT TAKE if
NSAID Ibuprofen T: pain, fever, inflammation Cardiac events
allergic to
sulfonamide’s

Liver failure Assesses (Liver

Tylenol/ A: acts on cells of hypothalamus
T: pain, fever
Do not exceed 3 g 1 day Function Test) LFTs/

NON Salicylate acetaminophen

Toxicity S/S (shock syndrome) BUN/Creatinine
Alcohol use?
Antidote: acetylcysteine/Mucomyst

A: blocks Cox 2 GI events/Bleed

Cox 2 Inhibitors Celecoxib T: arthritic pain Fewer GI/Cardiac events —->>> safer for long term use
*need prescription
(Celebrex)
Corticosteroids Prednisone A: varies
T: decreases inflammation
Hyperglycemia Humpback
Moon face Mood instability *Fludro = headaches

-sone OR -olone Fludrocortisone tx: Addison’s adrenal insufficiency Weight game Cushing’s S/S

A: react with opioid receptors to control Ad. React: respiratory depression, constipation, cardiac

Opioid Agonist Morphine severe pain

T: pain, sedation, euphoria
arrest, shock, addictive,
Misc: do not take with alcohol, have patient take stool
softeners (constipation)

Narcotic Naloxone A: binds to receptors, DOES NOT activate

them
Ad. React: tachycardia, blood pressure,
changes, dysrhythmias

Antagonist (Narcan) T: opioid overdose, reverses respiratory,

depression, sedation, hypotension
A: block alpha, adrenergic and serotonin Ad. React: cardiovascular effects,
Ergot Derivatives Ergotamine receptor sites, decreases hyperfusion in
arterial vascular bed
numbness/tingling,
confusion.
(Prevent headaches)
(Meds taken daily) (Ergomar) T: migraine and vascular headaches Misc: don’t take if patient has
coronary artery disease/
hypertension/pulmonary vascular
disease

A: bind to selective serotonin receptor Ad. React: CNS overload (burning/cold,

Triptans Sumatriptan sites to cause vasoconstriction numbness/tingling, tiredness/weakness,
dysphagia)
T: acute migraines
(DOES NOT PREVENT
ACUTE MIGRAINES)
(Imitrex) Misc: do not take with other migraine meds,
too much vasoconstriction caused

Cannabis A: CNS depressant

T: chemo, pain, spasticity from MS,
Ad. React: increased heart rate, sleepiness, dizziness,
hallucinations, paranoia, possible dependency
(medical marijuana) neuropathies Misc: plantform not approved, dronabinol and nabilone
FDA approved

A: stimulates immune system, decreases Ad. React: bitter taste, mild G.I. reaction, allergies
inflammation
Herbal Echinacea T: TB, HIV, cancer
Misc: teach patient not to use for prolonged time

A: make Cartilage/synovial fluid suppress Ad. React: mild GI rxn, use cautiously, if allergic to
Glucosamine inflammation
T: osteoarthritis
shellfish
Misc: don’t take if on antiplatelet/anticoagulant
(increases bleeding risk)