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Material Safety Data Sheet

Acetone MSDS

$ettion1: Chemical Product and Company ldentiflcatlon

Product Name: Acetone Contact Information:

Catalog Codes: SLA3502, SLA1645, SLA3151, SLA3808 Sciencelab.com, Inc.

14025 Smith Rd.
CAS#: 67-64-1 Houston, Texas 77396

US Sales: 1-800-901-7247
RTECS: AL3150000
International Sales: 1-281-441-4400
'CA: TSCA 8(b) inventory: Acetone Order Online: ScienceLab.com

CI#: Not applicable. CHEMTREC (24HR Emergency Telephone), call:

1-800-424-9300
Synonym: 2-propanone; Dimethyl Ketone:
Dimethylformaldehyde; Pyroacetic Acid International CHEMTREC, call: 1-703-527-3887

Chemical Name: Acetone For non-emergency assistance, call: 1-281-441-4400

Chemical Formula: C3-H6-0

Section 2: Composition and Information on Ingredients

Composition:

';~7:ne~-=- 1~;~4~
,--. &_o~_y_we_~g_.
hI -~.__

Toxicological Data on Ingredients: Acetone: ORAL (LDSO):Acute: 5800 mg/kg [Rat). 3000 mg/kg [Mouse). 5340 mg/kg
__ -='
rqabbit]. VAPOR (LC50): Acute: 50100 mg/m 8 hours [Rat]. 44000 mg/m 4 hours [Mouse].

Section 3: Hazardsldentification
Potential Acute Health Effects:
Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous
in case of skin contact (permeator).

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male·
[SUSPECTED].
The substance is toxic to central nervous system (CNS).
The substance may be toxic to kidneys, the reproductive system, liver, skin.
Repeated or prolonged exposure to the substance can produce target organs damage.

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 Section 4: First Ai~ Measlrres
Eye Contact:
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,
keeping eyelids open. Cold water may be used. Get medical attention.

Skin Contact:
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Cold water may be used. Wash clothing before reuse. Thoroughly clean shoes
before reuse. Get medical attention.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical
attention.

Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention if symptoms appear.

Serlous Inhalation:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical attention .

.gestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if
symptoms appear.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Flammable.

Auto-Ignition Temperature: 465°C (869°F)

Flash Points: CLOSED CUP: -20°C (-4°F). OPEN CUP: -9°C (15.8°F) (Cleveland).

Flammable Limits: LOWER: 2.6% UPPER: 12.8%

Products of Combustion: These products are carbon oxides (CO, C02).

're Hazards in Presence of Various Substances: Highly flammable in presence of open flames and sparks, of heat.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.
Slightly explosive in presence of open flames and sparks, of oxidizing materials, of acids.

Fire Fighting Media and Instructions:

Flammable liquid, soluble or dispersed in water.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use alcohol foam, water spray or fog.

Special Remarks on Fire Hazards: Vapor may travel considerable distance to source of ignition and flash back.

Special Remarks on Explosion Hazards:

Forms explosive mixtures with hydrogen peroxide, acetic acid, nitric acid, nitric acid + sulfuric acid, chromic anydride,
chromyl chloride, nitrosyl chloride, hexachloromelamine, nitrosyl perchlorate, nitryl perchlorate, permonosulfuric acid,
thiodiglycol + hydrogen peroxide, potassium ter-butoxide, sulfur dichloride, 1-methyl-1 ,3-butadiene, bromoform, carbon,
air, chloroform, thitriazylperchlorate.

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 S~ct'i()n6: Accidental R~lease Measures
Small Spill:
Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal
container.

Large Spill:
Flammable liquid.
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,
sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or
confined areas; dike if needed. Be careful that the product is not present at a concentration level above TLV.
Check TLV on the MSDS and with local authorities.

Section 7: Handling and Storage

Precautions:
Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing
material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of
insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and
show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as
oxidizing agents, reducing agents, acids, alkalis.

prage:
.iore in a segregated and approved area (flammables area) . Keep container in a cool, well-ventilated area.
Keep container tightly closed and sealed until ready for use. Keep away from direct sunlight and heat and avoid all
possible sources of ignition (spark or flame).

Section 8: Exposure Controls/Personal Protection

Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the
work-station location.

Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.

.xposure Limits:
TWA: 500 STEL: 750 (ppm) from ACGIH (TLV) [United States]
TWA: 750 STEL: 1000 (ppm) from OSHA (PEL) [United States]
TWA: 500 STEL: 1000 [Austalia]
TWA: 1185 STEL: 2375 (mgfm3) [Australia]
TWA: 750 STEL: 1500 (ppm) [United Kingdom (UK)]
TWA: 1810 STEL: 3620 (mg/m3) [United Kingdom (UK)]
TWA: 1800 STEL: 2400 from OSHA (PEL) [United States]Consult local authorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid.

Odor: Fruity. Mint-like. Fragrant. Ethereal

Taste: Pungent, Sweetish

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I ~'olecul~; W~i9ht: 58.08 g/mole

Color: Colorless. Clear

pH (1% soln/water): Not available.

Boiling Point: 56.2°C (133.2°F)

Melting Point: -95.35 (-139.6°F)

Critical Temperature: 235°C (455°F)

Specific Gravity: 0.79 (Water = 1)

Vapor Pressure: 24 kPa (@ 20°C)

Vapor Density: 2 (Air = 1)

Volatility: Not available.

Odor Threshold: 62 ppm

Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -0.2

.;hicity (in Water): Not available.

Dispersion Properties: See solubility in water.

Solubility: Easily soluble in cold water, hot water.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Excess heat, ignition sources, exposure to moisture, air, or water, incompatible materials.

Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, acids, alkalis.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Not available.

~ecialRemarks on Corrosivity: Not available.

Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation.

Toxicity to Animals:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE.
Acute oral toxicity (LD50): 3000 mg/kg [Mouse].
Acute toxicity of the vapor (LC50): 44000 mg/m3 4 hours [Mouse].

Chronic Effects on Humans:

CARCINOGENIC EFFECTS: A4 (Not classifiable for human or anirnal.) by ACGIH.

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O'EVELO'PMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male
[SUSPECTED].
Causes damage to the following organs: central nervous system (CNS).
May cause damage to the following organs: kidneys, the reproductive system, liver, skin.

Other Toxic Effects on Humans:

Hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Slightly hazardous in case of skin contact (permeator).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans:

May affect genetic material (mutagenicity) based on studies with yeast (S. cerevisiae), bacteria, and hamster
fibroblast cells. May cause reproductive effects (fertility) based upon animal studies.
May contain trace amounts of benzene and formaldehyde which may cancer and birth defects. Human: passes
the placental barrier.

Special Remarks on other Toxic Effects on Humans:

Acute Potential Health Effects:
Skin: May cause skin irritation. May be harmful if absorbed through the skin.
Eyes: Causes eye irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible
corneal injury.
Inhalation: Inhalation at high concentrations affects the sense organs, brain and causes respiratory tract irritation.
also may affect the Central Nervous System (behavior) characterized by dizzness, drowsiness, confusion,
.eadache, muscle weakeness, and possibly motor incoordination, speech abnormalities, narcotic effects and
coma. Inhalation may also affect the gastrointestinal tract (nausea, vomiting).
Ingestion: May cause irritation of the digestive (gastrointestinal) tract (nausea, vomiting). It may also affect the
Central Nevous System (behavior), characterized by depression, fatigue, excitement, stupor, coma, headache,
altered sleep time, ataxia, tremors as well at the blood, liver, and urinary system (kidney, bladder, ureter) and
endocrine system. May also have musculoskeletal effects.
Chronic Potential Health Effects:
Skin: May cause dermatitis.
Eyes: Eye irritation.

Section 12: EcologicaJ Information

Ecotoxicity:
Ecotoxicity in water (LC50): 5540 mg/l 96 hours [Trout]. 8300 mg/l 96 hours [Bluegill]. 7500 mg/I 96 hours
[Fatthead Minnow]. 0.1 ppm any hours [Water flea].

BOD5 and COD: Not available.

Products of Biodegradation:
psslbly hazardous short term degradation products are not likely. However, long term degradation products may
Aise.

Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.

Special Remarks on the Products of Biodegradation: Not available.

Se.ction 1.3: Disposal Considerations

Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental
control regulations.

Sectioo 14: Transpertlnfcrmatlen

DOT Classification: CLASS 3: Flammable liquid.

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 . >
'

L l;entific~~iO~: : Acetone UNNA: 1090 PG: "

Special Provisions for Transport: Not available.

Secti(;)n 1'5: Other Regulatory Information

Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause reproductive harm (male) which would require a warning under the statute: Benzene
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: Benzene
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause cancer which would require a warning under the statute: Benzene, Formaldehyde
Connecticut hazardous material survey.: Acetone
Illinois toxic substances disclosure to employee act: Acetone
Illinois chemical safety act: Acetone
New York release reporting list: Acetone
Rhode Island RTK hazardous substances: Acetone
Pennsylvania RTK: Acetone
Florida: Acetone
Minnesota: Acetone
l'v1assachusetts RTK: Acetone
assachusetts spill list: Acetone
I'-JewJersey: Acetone
New Jersey spill list: Acetone
Louisiana spill reporting: Acetone
California List of Hazardous Substances (8 CCR 339): Acetone
TSCA 8(b) inventory: Acetone
TSCA 4(a) final test rules: Acetone
TSCA 8(a) IUR: Acetone

Other Regulations:
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada):
CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).
CLASS 0-2B: Material causing other toxic effects (TOXIC).

DSCL (EEC):
R11- Highly flammable.
,36-Irritating to eyes.
09- Keep container in a well-ventilated place.
S 16- Keep away from sources of ignition - No
smoking.
S26- In case of contact with eyes, rinse
immediately with plenty of water and seek
medical advice.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 3

Reactivity: 0

Personal Protection: h

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National Fire Protection Association (U.S.A.):

Health: 1

Flammability: 3

Reactivity: 0

Specific hazard:

Protective Equipment:
Gloves.
Lab coat.
Vapor respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.

Section 16: ()therlnformation

~eferences:
laterial safety data sheet issued by: la Commission de la SantA.© et de la SA.©curitA.© du Travail du QuA©bec.
- r'he Sigma-Aldrich Library of Chemical Safety Data, Edition II.
-Hawley, G.G .. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987.
LOll, RTECS, HSDB databases.
Other MSDSs

Other Special Considerations: Not available.

Created: 10/10/200508:13 PM

Last Updated: 11/06/2008 12:00 PM

The information above is believed to be accurate and represents the best information currently available to us. However, we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
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if ScienceLab.com has been advised of the possibility of such damages.

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