1. Total number of P.I.

(x) of tetrachloro cyclobutane can show geometrical isomers (y) than find out x + y:

(a) 2 (b) 6

(c) 8 (d) 7

2. Number of fractions on fractional distillation of mixture of :

(a) 2 (b) 1

(c) 4 (d) 3

CH 3 – CH – CH – CH – CH 3
| | |
3. Total number of optically active stereoisomers of Cl Cl Cl .

(a) 2 (b) 6

(c) 4 (d) 3

4. How many spatial orientations are possible in the following compound ?

(a) 2 (b) 6

(c) 4 (d) 8

5. Total number of stereoisomers of compound is :

CH 3  CH  CH  CH 3
| |
OH Br

(a) 2 (b) 6

(c) 4 (d) 3

6.Total number of optically active stereoisomers of tartaric acid are

(a) 2 (b) 1

(c) 4 (d) 3
7. The total number of ketones (including stereo isomers) with the molecular formula C 6H12O is :

(a) 3 (b) 7

(c) 4 (d) 8

8. The sum of total stereoisomers and fractions on the fractional distillation of 2, 3- Dichloropentane is.

(a) 2 (b) 6

(c) 4 (d) 3

CH 3 – CH – CH  CH – CH – CH 3
| |
Cl Cl
9. Total number of optically stereoisomers of are :

(a) 2 (b) 6

(c) 4 (d) 3

10. Total number of optical active stereoisomers of the following compound are :

CH3 – CH = CH – CHCl – CH = C = CH – CH = CH – CH3

(a) 8 (b) 16

(c) 32 (d) 12

11. Total number of position isomers of trichlorocyclohexane which can show geometrical isomerism.

(a) 2 (b) 3

(c) 4 (d) 6

12. Which of the following pairs of compounds are enantiomers :

CH 3 CH 3
H OH HO H
OH H H OH

(a) CH 3 and CH 3
 CH 3 CH 3
H OH HO H
HO H HO H

(b) CH 3 and CH 3

CH 3
H OH
H OH

(c) and CH 3

CH 3 CH 3
HO H HO H
H OH HO H

(d) CH 3 and CH 3

13. The configuration of the given compound is :

(a) E (b) R

(c) S (d) Z

14. Which one of the following pair represents stereo isomerism :-

(a) Linkage isomerism and Geometrical isomerism

(b) Chain isomerism and Rotational isomerism

(c) Optical isomerism and Geometrical isomerism

(d) Structural isomerism and Geometrical isomerism.

15. Which of the following is not chiral ? 

(a) 2–Butanol (b) 2, 3–Dibromo pentane

(c) 3–Bromo pentane (d) 2–Hydroxy propanoic acid

16. Among the following which one can have a meso form ? 

(a) CH3CH(OH)CH(CI)C2H5 (b) CH3CH(OH)CH(OH)CH3

(c) C2H5CH(OH)CH(OH)CH3 (d) HOCH2CH(CI)CH3

 17. CH3 – CHCI – CH2 – CH3 has a chiral centre which one of the following represents its R configuration :

C 2H 5 C 2H 5
| |
H — C — CH 3 CI — C — CH 3
| |
(a) CI (b) H

CH 3 C 2H 5
| |
H — C — CI H 3 C — C — CI
| |
(c) C 2H 5 (d) H

18. In the following the most stable conformation of n-butane is : 

(a) (b)

(c) (d)

19. Which of the following acids does not exhibit optical isomerism ?
(a) Maleic acid (b) -amino acids

(c) Lactic acid (d) Tartaric acid

20. Two possible stereo-structures of

CH3CHOH.COOH, which are optically active, are called.

(a) Diastereomers (b) Atropisomers

(c) Enantiomers (d) Mesomers

21. The correct statement regarding the comparison of staggered and eclipsed conformations of ethane, is:

(a) The staggered conformation of ethane is more stable than eclipsed conformation, because staggered
conformation has no torsional strain.

(b) The staggered conformation of ethane is less stable than eclipsed conformation, because staggered
conformation has torsional strain.

(c) The eclipsed conformation of ethane is more stable than staggered conformation, because eclipsed
conformation has no torsional strain.
 (d) The eclipsed conformation of ethane is more stable than staggered conformation even though the
eclipsed conformation has torsional strain.

22. Which of the following biphenyls is optically active

CH3 O2N

(a) CH3 (b) I

Br Br I

(c) I I (d) I

23. In which of the following molecules, all atoms are coplanar ?

(a) (b)

CH3 CN
C=C
CN
(c) (d) CH3

24. The correct corresponding order of names of four aldoses with configuration given below

CHO CHO CHO CHO

H OH HO H HO H H OH
H OH H OH HO H HO H
CH2OH CH2OH CH2OH CH2OH respectively, is

(a) D-erythrose, D-threose, L-erythrose, L-threose

(b) L-erythrose, L-threose, L-erythrose, D-threose

(c) D-threose, D-erythrose, L-threose, L-erythrose

(d) L-erythrose, L-threose, D-erythrose, D-threose

25. With respect to the conformers of ethane, which of the following statements is true?
(a) Bond angle remains same but bond length changes

(b) Bond angle changes but bond length remains same

(c) Both bond angle and bond length changes

 (d) Both bond angles and bond length remains same

26. The geometrical isomerism is shown by :-

CH 2
CH2

(a) (b)
CHCI
CHCI

(c) (d)

27. Correct configuration of the following is : -

CH 3

H OH

CH 3 OH

(a) 2S, 3S (b) 2S, 3R

(c) 2R, 3S (d) 2R, 3R

28. Among the following L–serine is : -

NH 2 CO 2 H CH 2 OH
CO 2 H

H CO 2 H HOH 2 C H N 2H CH 2 OH N 2H H

(a) CH 2 OH (b) NH 2 (c) H (d) CO 2 H

29. C8H16 that can form cis-trans geometrical isomers and also has a chiral centre, is

(a) (b)
(c) Both of these (d) None of these

30. Which will not show geometrical isomerism ?

(a) CH3CH = NOH (b)

(c) HO – N = N – OH (d) (CH3)2C = NOH

 31. Which is optically inactive ?
a a a a
C=C =C=C C=C =C
(a) b b (b) b b

a
d
N
e
(c) b (d) None of these

32. The compound CHCI CHCHOHCOOH with molecular formula C4H5O3Cl can exhibit 
(a) geometric, optical, position and functional isomerism.

(b) geometric. optical and functional isomerism only

(c) position and functional isomerism only

(d) geometric and optical isomerism only

33. Point out incorrect sawhorse drawing(s) for the following compound.

CH3

H Br

H Br

CH3

Br H
H Br
CH3 CH3
CH3 CH3
H H
(a) Br (b) Br

Br CH3
CH3 H CH3
Br
CH3 H
H H
(c) Br (d) Br

34. Which of the following are not enantiomer pair.

(a) A & B (b) A & D

 (c) B & D (d) C & D

35. For geometric isomers of 3–hexene :

(a) M.P. is high and dipole moment high for trans

(b) M.P. is low and dipole moment low for trans

(c) M.P. is high and dipole moment low for trans

(d) M.P. is low and dipole moment high for trans

36. Racemic mixture is formed by mixing two :

(a) Isomeric compounds (b) Chiral compounds
(c) Meso compounds (d) Optical isomers

37. Which of the following does not show geometrical isomerism ?

(a) 1,2-Dichloro-1-pentene (b) 1,3-Dichloro-2-pentene

(c) 1,1-Dichloro-1-pentene (d) 1,4-Dichloro-2-pentene

38. Among the following four structures I to IV.

CH 3 O CH 3
| || |
C 2 H 5 – CH – C 3H 7 CH 3 – C – CH – C 2H 5
(I) (II)

it is true that

(a) All four are chiral compounds (b) Only I and II are chiral compounds

(c) Only III is a chiral compound (d) Only II and IV are chiral compounds

39. Which of the following will have a meso-isomer also ?

(a) 2-Chlorobutane (b) 2,3-Dichlorobutane
(c) 2,3-Dichloropentane (d) 2-Hydroxypropanoic acid

40. Amongst the following compounds, the optically acitve alkane having lowest molecular mass is
 (a) CH3–CH2–CH2–CH3 (b)

(c) (d) CH3–CH2–CCH

41. Which of the following compounds is not chiral ?

(a) 1–Chloropentane (b) 2-Chloropentane

(c) 1-Chloro-2-methylpentane (d) 3-Chloro-2-methylpentane

42. Which type of isomerism is shown by 2,3-dichlorobutane ?

(a) diastereomerism (b) optical-isomerism

(c) geometric-isomerism (d) structural-isomerism

43. Increasing order of stability among the three main conformations (i.e. eclipse, anti, gauche) of 2-fluoroethanol is

(a) eclipse, gauche, anti (b) gauche, eclipse, anti

(c) eclipse, anti, gauche (d) anti, gauche, esclipse

44. Which one of the following conformations of cyclohexane is chiral?

(a) Chair (b) Boat
(c) Twist boat (d) Rigid

CO 2 H
HO 2 C

HO H
H
45. The absolute configuration of OH is
(a) R, R (b) R, S
(c) S, R (d) S, S

46. The alkene that exhibits geometrical isomerism is :

(a) 2-methyl propene (b) 2-butene
(c) 2-methyl-2-butene (d) propene
47. The number of stereoisomers possible for a compound of the molecular formula CH3–CH=CH–CH(OH)–Me is:

(a) 2 (b) 4

(c) 6 (d) 3

48. Out of the following, the alkene that exhibits optical isomerism is.
(a) 3-methyl-2pentene (b) 4-methyl-1-pentene
(c) 3-methyl-1-pentene (d) 2-methyl-2-pentene

49. Which of the following compound will exhibit geometrical isomerism ?

(a) 1-Phenyl-2-butene (b) 3-Phenyl-1-butene

(c) 2-Phenyl-1-butene (d) 1,1-Diphenyl-1-propane

50. The number of chiral centres in penicillin is

(a) 3.00 to 3.00 (b) 2.00 to 2.00

(c) 1.00 to 1.00 (d) None of these