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Q. Assertion: The chromosomal disorders are caused due to absence or excess or
abnormal arrangement of one or more chromosomes.
Reason: Failure of segregation of chromatids during cell division cycle results in
the gain or loss of a chromosome(s), called polyploidy.

A. Both Assertion and Reason are true, and the Reason is the correct explanation
of the Assertion.
B. Both Assertion and Reason are true, but the Reason is not the correct
explanation of the Assertion.
C. Assertion is true, but Reason is false.
D. Both Assertion and Reason are false.
Q. Assertion: Out of 23 pairs of chromosomes present in humans, 22 pairs are
exactly same in both males and females; these are the autosomes.
Reason: In humans, a pair of X chromosomes is present in the female, whereas the
presence of an X and Y chromosome are determinants of the male characteristic.

A. Both Assertion and Reason are true, and the Reason is the correct explanation
of the Assertion.
B. Both Assertion and Reason are true, but the Reason is not the correct
explanation of the Assertion.
C. Assertion is true, but Reason is false.
D. Both Assertion and Reason are false.
Q. Assertion: Pleiotropy should not be confused with polygenic traits.
Reason: In polygenic traits, multiple genes result in a single phenotype but in
pleiotropy one gene can exhibit multiple phenotypic expressions.

A. Both Assertion and Reason are true, and the Reason is the correct explanation
of the Assertion.
B. Both Assertion and Reason are true, but the Reason is not the correct
explanation of the Assertion.
C. Assertion is true, but Reason is false.
D. Both Assertion and Reason are false.
Q. Assertion: Since there are three different alleles for human blood groups, there
are six different combinations of these three alleles that are possible.
Reason: For human blood groups, there are three phenotypes possible.

A. Both Assertion and Reason are true, and the Reason is the correct explanation
of the Assertion.
B. Both Assertion and Reason are true, but the Reason is not the correct
explanation of the Assertion.
C. Assertion is true, but Reason is false.
D. Both Assertion and Reason are false.
Q. In a test cross involving F1 dihybrid flies, more parental-type offspring were
produced than the recombinant type offspring. This indicates

A. Chromosomes failed to separate during meiosis

B. The two genes are linked and present on the same chromosome
C. Both of the characters are controlled by more than one gene
D. The two genes are located on two different chromosomes
Q. A yellow round-seeded Pea plant is crossed with a green wrinkled-seeded Pea
plant. Four phenotypes appeared in the progeny in the ratio of 1 : 1 : 1 : 1. The
genotype of the two parents are

A. YyRr and yyrr

B. YYRR and yyrr
C. YYRr and yyrr
D. YyRR and yyrr
Q. An allele is dominant if it is expressed in

A. Both homozygous and heterozygous states

B. Second generation
C. Heterozygous combination
D. Homozygous combination
Q. Given pedigree show inheritance of autosomal dominant disorder (myotonic
dystrophy) then what will be the genotype of shaded symbols?

A. AA
B. Aa
C. AA or Aa
D. aa
Q. Select the incorrect statement.

A. In male grasshoppers, 50% of sperms have no sex chromosome

B. In domesticated fowls, the sex of progeny depends on the type of sperm
rather than egg
C. Human males have one of their sex-chromosome much shorter than the
other
D. Male fruit flies are heterogametic
Q. In the F2 generation of a Mendelian dihybrid cross the number of phenotypes
and genotypes are

A. phenotypes – 4; genotypes – 16
B. phenotypes – 9; genotypes – 4
C. phenotypes – 4; genotypes – 8
D. phenotypes – 4; genotypes – 9
Q. In a plant, red fruit (R) is dominant over yellow fruit (r) and tallness (T)
dominant over shortness (t). A plant with RRTt genotype is crossed with plant of
rrtt genotype. The progeny is

A. All red fruit, tall 25%

B. All red fruit, tall 50%
C. All red fruit, tall 75%
D. All red fruit and tall
Q. A couple has six daughters. What is the possibility of their having a girl next
time?

A. 10%
B. 50%
C. 90%
D. 100%
Q. Which of the following is correct?

A. Birds have ZZ (female) – ZW (male) sex determination

B. Drosophila has XX-XY sex determination
C. Henking discovered the Y chromosome
D. Grasshoppers show XX-XY sex determination
Q. When a cross is made between a tall plant with yellow seeds (Tt Yy) and a tall
plant with green seeds (Tt yy), what is true regarding the proportions of
phenotypes of the offsprings in F1 generation?

A. Proportion of Tall and Green-3/8 , Proportion of Dwarf and Green-1/8

B. Proportion of Tall and Green-2/8 , Proportion of Dwarf and Green-1/8
C. Proportion of Tall and Green-1/8 , Proportion of Dwarf and Green-3/8
D. Proportion of Tall and Green-2/8 , Proportion of Dwarf and Green-2/8
Q. Which of the following is not an example of recessive autosomal disease?

A. Haemophilia
B. Cystic fibrosis
C. Phenylketonuria
D. Sickle-cell anaemia
Q. Match Column-I with Column-II and select the correct option from the codes
given below.

A. A-(iii), B-(iv), C-(ii), D-(i)

B. A-(iii), B-(ii), C-(iv), D-(i)
C. A-(i), B-(iv), C-(ii), D-(iii)
D. A-(i), B-(ii), C-(iv), D-(iii)
Q. Due to nondisjunction of chromosomes during spermatogenesis, some sperms
carry both sex chromosomes (22A + XY) and some sperms do not carry any sex
chromosome (22A + O). IF these sperms fertilize normal eggs (22A + X), what
types of genetic disorders respectively appear among the offsprings?

A. Klinefelter’s syndrome and Turner’s syndrome

B. Turner’s syndrome and Klinefelter’s syndrome
C. Down’s syndrome and Turner’s syndrome
D. Down’s syndrome and cri-du-chat syndrome
Q. Which among the following is not a mendelian disorder?

A. Colour Blindness
B. Haemophilia
C. Sickle-cell anaemia
D. Turner’s Syndrome
Q. Find out the mismatched pair.

A. Haemophilia – Sex linked recessive

B. Cystic fibrosis – Autosomal recessive
C. Down’s syndrome – Trisomy 21
D. Turner’s syndrome – Y-linked recessive
Q. Down’s Syndrome, Klinefelter’s Syndrome, and Turner’s Syndrome are
examples of---.

A. polyploidy
B. autosomy
C. point mutations in sex chromosomes
D. aneuploidy
Q. The disease sickle-cell anaemia is caused by the substitution of (i) by (ii) at the
(iii) position of (iv) globin chain of haemoglobin molecule.
Which of the following correctly fills the blanks in the above statement?

A. (i) valine, (ii) glutamic acid, (iii) sixth, (iv) beta

B. (i) glutamic acid, (ii) valine, (iii) sixth, (iv) beta
C. (i) glutamic acid, (ii) valine, (iii) fifth, (iv) beta
D. (i) valine, (ii) glutamic acid, (iii) fifth, (iv) beta
Q. Which one of the following condition in human is correctly matched with its
chromosomal abnormality/linkage?

A. Klinefelter’s syndrome – 44 autosomes + XXY

B. Colourblindness – Y-linked
C. Erythroblastosis foetalis – X-linked
D. Down syndrome – 44 autosomes + XO
Q. Colour blindness is a

A. sex linked dominant disorder

B. sex linked recessive disorder
C. autosomal dominant disorder
D. autosomal recessive disorder
Q. In the following human pedigree, the filled symbols represent the affected
individuals. Identify the type of given pedigree.

A. X-linked dominant
B. Autosomal dominant
C. X-linked recessive
D. Autosomal recessive
Q. Alleles are:

A. Chromatids
B. Chromosomes
C. Isomers of a gene
D. Alternate forms of a gene
Q. Which of the following is the example of sex-linked disease?

A. AIDS
B. Colour blindness
C. Syphilis
D. Gonorrhoea
Q. Which of the following is incorrect regarding ZW-ZZ type of sex determination?

A. It occurs in birds and some reptiles

B. Females are homogametic and males are heterogametic
C. 1 : 1 sex ratio is produced in the offsprings
D. Only females can form different types of gametes while males can't
Q. In humans, height is not a binary thing, that is either tall or short. It can show a
lot of variation where a lot of intermediates are present. It is an example of

A. Multiple alleles
B. Pleiotropic inheritance
C. Polygenic inheritance
D. Pseudoalleles
Q. Given diagram shows a pair of homologous chromosomes during meiosis.

Maximum crossing over will occur between genes

A. A and a, D and d
B. C and d, c and D
C. B and c, b and C
D. A and d, a and D
Q. A gene showing codominance has

A. One allele dominant on the other

B. Alleles tightly linked on the same chromosome
C. Alleles that are recessive to each other
D. Both alleles independently expressed in the heterozygote
Q. The types of gametes formed by the genotype RrYy are

A. RY, Ry, rY, ry

B. RY, Ry, ry, ry
C. Ry, Ry, Yy, ry
D. Rr, RR, Yy, YY
Q. Which one is incorrect?

A. Polygenic character is controlled by multiple genes

B. Numerous intermediate types are found in between the two extremes in
polygenic inheritance
C. Height, weight and skin colour are polygenic
D. Polygenic trait is controlled by multiple alleles
Q. A man has enlarged breasts, sparse hair on the body and sex chromosomal
formula XXY. He then suffers from

A. Down syndrome
B. Edward syndrome
C. Turner syndrome
D. Klinefelter syndrome
Q. Blood grouping in human beings is controlled by

A. 4 alleles in which A is dominant

B. 3 alleles in which A and B are codominant, and i is recessive
C. 3 alleles in which none is dominant
D. 3 alleles in which A is dominant
Q. Which of the following characteristics represent ‘Inheritance of blood groups in
humans?
1. Dominance
2. Codominance
3. Multiple alleles
4. Incomplete dominance
5. Polygenic inheritance

A. 2, 4 and 5
B. 1, 2 and 3
C. 2, 3 and 5
D. 1, 3 and 4
Q. The genotypes of a Husband and Wife are IAIB and IAi and . Among the blood
types of their children, how many different genotypes and phenotypes are
possible.

A. 3 genotypes; 3 phenotypes
B. 3 genotypes; 4 phenotypes
C. 4 genotypes; 3 phenotypes
D. 4 genotypes; 4 phenotypes
Q. Test cross involves

A. Crossing between two genotypes with recessive trait

B. Crossing between two F1 hybrids
C. Crossing the F1 hybrid with a double recessive parent
D. Crossing between two genotypes with dominant trait
Q. When a violet flower of an unknown genotype is crossed with a white flower, the
progenies are violet and
white in equal proportion. Then read the following statements.
(i) This is called test cross
(ii) Unknown flower is homozygous
(iii) Unknown flower is heterozygous
(iv) This test is used to determine the phenotype of the plant at F2
(v) For a test cross to be carried out, either violet or white flowers should be
crossed with the recessive
parent instead of self-crossing.
Select the option representing all the incorrect statements:

A. (iii), (iv), (v)

B. (ii), (iv)
C. (i), (ii), (v)
D. (ii), (iv), (v)
Q. The figure below shows three types of sex determination. Select the option
giving correct identification.

A. C - ZZ males, ZW females
B. A - XO Males, XX females
C. B - XY females, XX males
D. C - ZZ females, XX males
Q. The inheritance of flower colour in Antirrhinum sp. (dog flower) is an example
of

A. Incomplete dominance
B. Co-dominance
C. Multiple alleles
D. Linkage
Q. What is the probability of production of dwarf offsprings in a cross between two
heterozygous tall pea plants?

A. Zero
B. 50%
C. 25%
D. 100%
Q. Failure of cytokinesis after telophase stage of cell division results in an increase
in a whole set of chromosomes in an organism. The phenomenon is called as

A. Polyploidy
B. Aneuploidy
C. Haploidy
D. Diploidy
Q. If a genetic disease is transferred from a phenotypically normal but carrier
female to only some of the male progeny, the disease is

A. Autosomal dominant
B. Autosomal recessive
C. Sex-linked dominant
D. Sex-linked recessive
Q. A single heterozygous yellow wrinkled seeded Pea plant shall produce gametes
with the genetic constitution

A. YR only
B. Yr only
C. Yr and yr
D. YR and yR
Q. In honey bees, females are (i) having (iii) chromosome and males are (iii)
having (iv) chromosomes

A. (i)-diploid; (ii)-46; (iii)-Haploid; (iv)-23

B. (i)-Haploid; (ii)-23; (iii)-Diploid; (iv)-46
C. (i)-Diploid; (ii)-32; (iii)-Haploid; (iv)-16
D. (i)-Haploid; (ii)-16; (iii)-Diploid; (iv)-32
Q. Which one of the following traits of garden pea studied by Mendel was a
recessive feature?

A. Green pod colour

B. Round seed shape
C. Axial flower position
D. Green seed colour
Q. The possibility of a female becoming haemophilic is extremely rare because
mother of such a female has to be at least __(i)__ and father should be
__(ii)__ .

A. (i) haemophilic, (ii) carrier

B. (i) carrier, (ii) haemophilic
C. (i) haemophilic, (ii) normal
D. (i) haemophilic, (ii) haemophilic
Q. Trisomy is represented by

A. (2n - 1)
B. (2n - 2)
C. (2n + 2)
D. (2n + 1)
Q. Which of the following is a mismatched pair of disease and its related
symptom?

A. Disease – Phenylketonuria; Symptom – Urine turns black on exposure to air

B. Disease – Down’s syndrome; Symptom – Physical and mental retardation
C. Disease – Klinefelter’s syndrome; Symptom – Sterile males
D. Disease – Turner’s syndrome; Symptom – Sterile females
Q. Which one of the following conditions correctly describes the manner of
determining the sex in the given example?

A. XO type of sex chromosomes determine male sex in grasshopper

B. XO condition in humans as found in Turner syndrome, determines female sex
C. Homozygous sex chromosomes (XX) produce male in Drosophila
D. Homozygous sex chromosomes (ZZ) determine female sex in birds