Ref 4 History
Ref 4 History
© Copyright 2022
Borgstadt et al. This is an open access 1. Medical Science, A.T. Still University, Phoenix, USA 2. Clinical Informatics, Academic Affairs, HonorHealth and
article distributed under the terms of the College of Health Solutions, Arizona State University, Scottsdale, USA 3. Research, HonorHealth, Scottsdale, USA
Creative Commons Attribution License CC-
BY 4.0., which permits unrestricted use,
Corresponding author: Joshua T. Borgstadt, [email protected]
distribution, and reproduction in any
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source are credited.
Abstract
Healthcare managers and clinicians are inefficient in the processes of workflows and documentation. The
inefficiency is due in part by increasing demands of insurance companies, regulatory demands from the
government, and human error. Artificial intelligence (AI) can improve healthcare processes by decreasing
variability, thus improving patient and physician experience and patient outcomes. This project brings
together a panel of five experts to discuss problems in medicine and some of the tools available through AI
and technology to address these problems. The symposium modeled a "flipped classroom" format. The first
five 20-minute modules were uploaded to a web-based platform for viewing in advance of the 60-minute
moderated roundtable (Zoom, Zoom Video Communications, San Jose, CA, USA). The following themes
emerged after reviewing the transcribed data: data privacy and access (N=3, number of times identified);
process improvement (N=2); physician experience (N=1); value in data (N=2); and bias in healthcare and AI
(N=3). For AI to become implemented on a large scale in healthcare, many areas will need continued
discussion and research, including a continued look into how AI can add value to workflow and knowledge
augmentation. In addition, standards for the implementation of AI and a methodical approach to the
analysis of the effectiveness of algorithms coupled with training of healthcare professionals in the language
of AI algorithms will be helpful to ensure that AI is integrated safely.
Introduction
According to a report by Johns Hopkins, medical errors are now the third leading cause of death behind
cardiovascular disease and cancer [1]. The study details inefficient processes and distracted and inconsistent
care as causative factors, not bad doctors. Medicine is a profoundly personal profession, especially in
primary care. Providers take care of patients from the womb to the tomb and everything in between. A
patient has an expectation for their primary care provider to be empathetic and knowledgeable in their craft.
Instead, individuals often encounter burned-out providers, overburdened by inefficient documentation
within electronic medical records, inefficient processes, and inadequate clinic staffing [2]. The pandemic has
highlighted the importance of adequate staff, the mental and physical health of staff, and an efficient
process for a health system to meet the growing demands of the public. Often, the realities of a complex
system that cannot function at the highest level loom large over the reality of the public in desperate need of
the proper care at the right time.
The 2021 update of the Commonwealth Fund, which looks into health outcomes among high-income
countries, does not cast a favorable view of the United States healthcare system [3]. The report looked at 71
measures across five areas: access to care, care process, administrative efficiency, equity, and health
outcomes [3]. The United States was last overall. The United States came in second on measuring care
processes; however, it ranked last on the remaining four measures [3]. This rank is in stark contrast to the
number of dollars spent on healthcare in the United States. The United States far outspends the other
countries regarding the percentage of gross domestic product on related healthcare dollars [3]. Artificial
intelligence (AI) is gaining attention as a disruptor of the status quo in medicine. Great promise and
potential lie within AI as a growth agency to improve process efficiency and care within medicine.
AI is considered by many the most recent industrial revolution, detailed in an article in Forbes entitled, "The
4th Industrial Revolution Is Here, Are You Ready?" [4]. AI has revolutionized the way we communicate and
interact with the supply chain and has increased efficiency in multiple industries, ultimately increasing
profit margins. According to a white paper from Accenture, AI can increase healthcare profits by 55% by the
year 2035 [5]. Integration of AI into primary care is part of this growth. Currently, AI is being used and
tested in specialties such as radiology, cardiology, and oncology [6,7]. Specialties that are dependent on
imaging have seen the rapid acceptance of AI pilot programs due to the ability of AI to synthesize large data
sets, evaluate, and accurately diagnose. Some of these AI programs are showing accuracy in diagnosis to the
Healthcare organizations have begun to adopt AI systems and have successfully implemented aspects of this
technology into their daily process. However, AI has yet to gain full acceptance throughout healthcare. AI
has the potential to garner mainstream attention; however, it must first gain the trust of patients, providers,
and staff while showing viability as a business model within clinics and health systems.
This project looks at the themes garnered from a thematic analysis of an online symposium on AI in
medicine. The objectives of the symposium include 1) current trends in AI in medicine; 2) short-term and
long-term potential of AI in medicine to address issues such as patient access, patient engagement, and
patient safety; and 3) understanding the current barriers to the implementation and utilization of AI in
medicine.
For the evaluation of themes, a topical literature search was conducted utilizing Google Scholar (Google,
Mountain View, CA, USA) with the following queries: AI and data privacy and data access, AI and process
improvement, AI and physician's experience, AI and bias in healthcare, and AI and value in data. Articles
with a published date of January 2020 to the present were considered (Table 1).
Objectives
Session title (speaker
initials)
1. Describe the clinical concepts in AI. 2. Provide examples of how AI is used in clinical practice, including ambulatory
Principles in AI (CF)
and inpatient medicine. 3. Develop the strategies to implement AI and to improve healthcare outcomes.
1. Discuss the etiology of bias in healthcare data. 2. Describe the consequences of biases in data, AI, and machine
Bias in AI (CN)
learning systems. 3. Apply the strategies to acknowledge and eliminate bias in data systems.
Relationship between AI and 1. Review the role of administrative burden on the incidence of clinician burnout. 2. Develop an AI infrastructure that may
clinician burnout (RC) improve both the patient and clinician experience.
1. Compare and contrast the case-based scenarios in the use of AI in clinical medicine. 2. Analyze the mechanisms for
Case studies in AI (EK)
improving the integration of AI in medicine.
1. Discuss "why we do what we do" in medicine (i.e., patient access, patient engagement, quality improvement, patient
Moderated roundtable
safety, medical innovation) and the role of AI in these processes. 2. Synthesize the key challenges in data and AI
discussion with all
infrastructure for the next 5-10 years in healthcare. 3. Recommend the strategies to improve our approach to healthcare
presenters (JB)
outcomes (using a data-driven approach).
Theme quantification
Data from the symposium were synthesized utilizing an iterative process. The transcription was analyzed,
and the section below reflects the synthesis of themes followed by quotes from presenters supporting the
themes. The discussion section applies medical literature to each theme for further evaluation.
One solution discussed by presenters is training in basic algorithms, data governance, and interoperability.
Patients and healthcare professionals generally lack an understanding of AI and data management. Tech
companies like Google and Amazon have a competitive advantage over health systems concerning data
governance and algorithm management. Understanding how data scientists and engineers create and
evaluate algorithms is essential for healthcare professionals to engage in data management. Healthcare
professionals must engage in conversations around data management if health systems want to be
competitive in the health tech market. Training in data management for healthcare professionals,
administrators, and patients is an important step to help create and maintain privacy standards and improve
data sharing between organizations.
"How are we going to survive and make this transition into sort of a data-centric model, versus having all
these silos where, you know, we're very protective of our data, but how do we engage with other
organizations, how do we leverage the power of, um, data sharing in a way that maintains privacy?" EK
"AI now relies a lot on EHR data, but we are thinking about smartphones, wearable devices, huge amounts of
data that patients are collecting, and patients are not sure they want to share that data. Do they want more
transparency on how the data is being used?" AG
"I mean, when we go to a clinician and tell them, hey, here's a bunch of data, I mean, they're going to be
interested for about six seconds, because they know that there's power in that, but it's sort of like taking a
drowning man in the middle of the Atlantic and handing him a glass of water and saying, "here, this is going
to be really good for you." RC
"If we do the work to be able to get information aggregated and accessible, will it actually be useful in a
clinical setting? Will it actually improve outcomes?" RC
Process improvement
"I think the low-hanging fruit, the problems that are solvable, the ones that are easy to measure, you know,
are often financial, did I collect more revenue, can I get more patients seen in a day, can I get better
utilization. Those are pretty discrete, right, and we can much more quickly and easily measure that" CF
"I think we have a lot of people in healthcare who just don't want to deal with it and they put their head in
the sand and say, 'no, I'm not going to do A.I. because I, no one can explain it,' and I think that that's a
mistake, because we're missing an incredible opportunity. That would be like, you know, a hundred plus
years ago and somebody says, 'yeah, you know what? I understand what you're talking about with germ
theory of disease, but I'm not going to participate in that because I don't believe it. You can't show me a
germ, I'm not going to believe it until you can.'" CN
Physician experience
Workflow-augmentation algorithms are being developed, utilizing natural language processing with
ambient voice technology that decreases provider documentation time allowing for more time in the room
with patients. ML and AI are being utilized to improve a provider's experience with chart documentation and
data entry, allowing a provider to spend more time in critical thinking and providing care to patients during
office visits and at the hospital's bedside. Increased provider documentation and data entry requirements are
linked to an increased percentage of medical error and burnout. With the implementation of algorithms
supporting workflow, a health system can improve quality measures of care and physician experience,
leading to improved overall patient care.
Knowledge augmentation is another area being explored through AI and ML methods. Companies are
developing algorithms to improve quality and decrease error with the ultimate goal to improve outcomes.
Chatbots have been developed and are being utilized as patient triage. Algorithms utilize large data sets and
deep AI to learn how to read radiographs and allow providers to use diagnosis assist in EMR systems. AI is a
tool, and knowledge augmentation is an area with great promise for deep AI algorithms to decrease
variability in care with the ultimate goal of improving outcomes. The lack of explanation in how a deep AI
algorithm produces a result is an ongoing concern for its use in medicine. Knowledge augmentation
continues to be an avenue of research.
"…. There's this other application, of A.I., around workflow augmentation. Taking things that are really
burdensome, but relatively easy, and taking those off of people's plates, making that process a lot easier.
And so we've seen that be very successful in other industries. I think it's been arguably even a more
successful approach to the application of A.I. in non-healthcare, but healthcare continues to focus on the
knowledge augmentation rather than workflow augmentation approach, relatively …
So, if you can walk out of the room with your chart note already written, and ninety percent of your
interview complete, and ninety-plus percent of your documentation complete … you're handing the clinician
all of the information that they need in the most actionable, usable format possible. That is certainly an
application of AI, to know what questions to ask, to know how to translate that information from the
patient-friendly interview, into a chart-ready [provider] note." RC
The panelists discussed the importance of finding the right tool for a particular problem. In process
improvement, finding the right tool involves understanding the problem compared to the end goal of
success: quality improvement, physician experience, and patient outcome. Variability in healthcare leads to
inconsistent care. Care should adhere to evidence-based guidelines and be consistent in quality and
delivery.
"I think a lot of us in healthcare are in it, yes to care for patients, but also to do it better, right, and we
recognize in process improvement, we need to decrease the variability, right. The variation in care needs to
get narrowed so that we can recognize if we are doing something right or wrong first, then we can correct it."
CN
Value in data
According to the 2021 Commonwealth Fund Report, the United States healthcare systems ranked last when
compared in 71 measures, when rated against other industrialized nations globally [3]. Technology can add
value to healthcare, but each program and algorithm must be strategically applied to the appropriate
problem. Each organization must consider the ability to implement, maintain, and monitor AI and ML
"Look at 23andMe. I mean, people pay a hundred plus dollars for the right to give up their genomic
information into an aggregate pool. Why'd they do it? Because they made it entertaining. It wasn't even a
direct monetary value, in fact it was an inverse monetary value, you had to pay money for the right to get
your information into that pool, and people just flowed in there because they made it engaging and
entertaining." RC
"How do you see balancing the massive amounts of data that are out there, that need to be able to use it
across some of those silos that have come up? But then, perhaps even more functionally, more importantly,
is taking that data and turning it into information. Making it actionable, making it valuable." RC
Data in healthcare have been biased due to the siloed nature of care the US healthcare system has created.
Each organization owns its data, and the sharing of data between various groups is complicated. Populations
served by various healthcare organizations may be homogenous, thus potentially creating a bias
toward particular groups of people. Evaluating a group of people to note diagnosis and attempt to risk
stratify the population is considered by the presenters as a way to help keep the focus of data on patient
outcomes. Bias in data can lead to inconsistent care among different populations, and variability can lead to
worse outcomes from a population standpoint.
"I want to maybe challenge everybody to think about it differently. It's actually exposing bias that's already
there, right. We are already treating people differently, and we're getting away with it because, once again,
they're in small scales that nobody has voiced it or it just hasn't been significant enough to be brought to
their attention. But, when an algorithm does it, oh my god, everybody has to stop and turn off the algorithm
and never use A.I. again." CN
"I’m excited that I think we’re going to find all kinds of different possibilities to take better care of our
patients, but I think, maybe, to go even back to some of the earlier conversation, we need to gain not just the
trust of the doctors on some of the algorithms and this, deep learning black box, you know, unexplainable
A.I. We need to gain the trust of our patients too, to let us use the data, because insofar as we don’t have a
kind of, heterogeneous population in our data, we’re going to have nothing but bias, and it’s going to
exaggerate some of the inconsistent delivery of medicine that we have now.” CN
“I think what we need to do instead, if we can’t explain all of the nodes through deep learning and the
machine learning component of it, we need to understand, what does that patient population look like,
right? It’s more like a nutrition label, it contains this many of this kind of person, this many diabetics, this
many hypertensives, this is their age, and apply it to a similar population to get the best results. And then
what you have to do, as somebody using that algorithm, is you need to actually apply it to your population
and let it run and make sure it’s giving you similar results before you turn it on and you have it start making
recommendations in changing care whatsoever.” CN
Discussion
The term artificial intelligence was first coined in 1956 by John McCarthy. He defined AI as "the science and
engineering of making intelligent machines” [10]. The field of AI is large and separated into different
Workflow augmentation is perhaps a more promising area for AI to provide meaningful assistance to
problem areas in billing, scheduling, and nursing workflows and triage. AI performs faster and more
efficiently than humans in billing, scheduling, accounting, and management of processes. AI chatbots can
improve efficiency in nursing and triage processes in the clinic [15]. Healthcare is a complex system of
professionals, departments, and institutions. Utilizing engineer planning paradigms such as Reach,
Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) and Systems Engineering Initiative
for Patient Safety (SEIPS) to evaluate, implement, and monitor AI-enabled systems within the culture of
each department the system interacts with provides an opportunity to collect data on how AI has addressed
a given process and decreased inefficiencies [16]. Instead of looking just at the tool's effectiveness, Li et al.
Data privacy and access is a critical issue and one in which policy and process must be developed to ensure
the safe acquisition and transfer of data in the healthcare sector. The exchange of patient data among
healthcare institutions, academic research, and industry can declassify sensitive information and allow
malicious data breaches [17]. Efforts must be taken to limit the risk of such data breaches. Before using an
extensive data set of patient information, understanding issues involving patient consent is essential [17].
Some ethics committees do not require consent for deidentified information, while some prefer to use an
opt-out method. This method could lead to bias as only the most engaged patients will be involved [17].
Value is an essential factor to consider when implementing a new product or service. The same is true for
healthcare and especially AI in healthcare. For a system or provider to change workflow, the value of the
change to the new service must be shown. The user and the consumer must see value in the service and gain
trust to utilize the service. The perceived risks to the implementation of AI include fear of new technology,
ethical or trust issues, and regulatory concerns [18]. Performance and communication concerns were noted
to be the highest predictor of risk belief among survey participants [18]. The panelists discussed the data and
the reality of data fatigue for the healthcare provider. The analysis of data should be meaningful for the
endpoint of a particular problem. Brault and Saxena discussed the large amounts of data collected with
mobile health technology and questioned the validity of the data due to inherent bias [19]. The authors
suggest the value of data is not just the amount collected but the appropriate evaluation and analysis of said
data [19].
Unconscious bias in healthcare is understood as the attitude and opinion toward a particular person or group
that affects perceptions by changing the way the care is provided [20]. Bias is inherent in the way medicine is
practiced. The siloed nature of care in the United States creates homogenous pools of patients that data are
pulled from research and process improvement projects. Algorithms expose bias already embedded in the
process due to the particular data set being studied, a theme that emerged in the discussion. Brault and
Saxena offer three principles to keep in mind for further research. The first principle is to create a catalog of
bias listing the source and ramifications of bias [19]. The second deals with creating standards for the use of
AI as a tool in medicine [19]. The third principle the authors discuss concerning the research of AI is to
develop an approach to evaluate and analyze the effectiveness of AI to solve a particular problem [19]. The
reality of AI and the change to specific processes and workflows in medicine will require training for
healthcare professionals in the basic language of AI and algorithms. Training will open up the world of AI to
professionals and help to safeguard this growing technology in the complex arena of medicine.
Limitations
Although approximately 50 people registered for the event, less than half were able to attend. Reasons for
this could be online meeting fatigue, time of day, and lack of good reminders. Although the event had
technical difficulties initially and the first five minutes was not captured, 52 minutes of discussion was
transcribed and analyzed. The symposium drew expert panelists from various aspects of the health
technology industry; however, more industry leaders should be included in this discussion, including, but
not limited to, experts on interoperability, health policy as it relates to AI and emerging technology, and
system strategy and management to evaluate new care models emerging through the use of AI.
The research for the analysis was conducted through Google Scholar. The search could have been expanded
to include other search engines to potentially include more articles for study. Words such as machine
learning, deep AI, and neural networks were uncovered with the search conducted; however, the search
could be completed using these words and others to potentially increase the article pool.
Conclusions
The panel discussion highlighted several issues to consider when thinking about the implementation of AI
into medicine. Data privacy and access is a critical issue and one in which policy and process must be
developed to ensure the safe acquisition and transfer of data in the healthcare sector. Many areas will need
Additional Information
Disclosures
Human subjects: All authors have confirmed that this study did not involve human participants or tissue.
Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue.
Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the
following: Payment/services info: All authors have declared that no financial support was received from
any organization for the submitted work. Financial relationships: All authors have declared that they have
no financial relationships at present or within the previous three years with any organizations that might
have an interest in the submitted work. Other relationships: This is meant to declare that potential
conflicts of interest may be present in this study. One panelist in the referenced symposium is also a
contributor to this paper. One panelist in the referenced symposium is also a founder and board member of
a company that utilizes artificial intelligence (AI) in electronic medical records. One panelist in the
referenced symposium is also a senior engineer with a major electronic medical record (EMR) company.
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