2024 Ec Content Study Manual Final
2024 Ec Content Study Manual Final
GRADE 12
WINTER CLASSES
Genetics
1
Suggested modified programme due to repetition of genetics which was
coveredduring Autumn Vacation Classes.
Genetics Pre- Test Marks decreased to 50 marks, questions
testing the same skillwere removed.
pg. 2 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
CONTENT PAGE
1. Blood groupings 4-7
2. How to tackle answering pedigree diagram questions 8 – 10
3. Dihybrid Crosses 10 - 13
4. Genetic engineering 13 - 15
5. Evidence of evolution 16 - 21
6. Causes of variation 22 – 26
7. Origin of an idea (Evolution theories) 27 – 35
8. Punctuated equilibrium 36 – 38
9. Natural VS Artificial Selection 39 – 41
10. Speciation 41 – 46
11. Reproductive isolation mechanisms 47 - 52
12. Evolution in present times 53 – 55
13. The place of humans in the phylogenetic tree 56 – 69
14. The “Out of Africa” Hypothesis 70 – 78
15. Acknowledgement 79
pg. 3 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
A. BLOOD GROUPINGS AS A RESULT OF MULTIPLE
ALLELES
Sometimes both alleles of a gene are equally dominant so the heterozygous
individual expresses both alleles, example: blood groups. Protein A and protein B are
coded by alleles IA and IB respectively. The allele i codes for no protein. This means
that there are three possible alleles for this one gene locus in humans. When there
are more than two possible alleles, it is termed multiple alleles. Any two of these
alleles will occur in combination in an individual. The alleles IA and IB are co-
dominant, and IA and IB completely dominate allele i.
When two individuals with AB blood type have children, the children can be type A,
type B or type AB.
pg. 4 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
B. CO-DOMINANCE IN HUMANS:
pg. 5 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
D. EXAMPLE OF A MONOHYBRID CROSS USING BLOOD TYPES
A man and a woman both have blood group B. Use a genetic cross to show how it is
possible for them to have a child with blood group O.
ACTIVITY A
1. Two newborn babies were accidentally mixed up at the hospital. In an effort to
determine the correct parents of each baby, the blood types of the babies and the
parents were determined as follows:
Baby 1 – type O Baby 2 – type A
Mr Smith – type AB Mrs Smith – type B
Mr Jones – type B Mrs Jones – type B
pg. 6 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
pg. 7 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
E. HOW TO TACKLE ANSWERING PEDIGREE DIAGRAM QUESTION
Step 3: Parents that are shaded shapes and produce only shaded shape offspring,
can be homozygous BB or heterozygous Bb. Look to the next generation and
then work backwards. Mark the parents on the pedigree diagram.
pg. 8 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Step 4: Answer the questions that relate to the pedigree diagram.
Try to work out the genotype of A, B, C, D, H, J, L, M and O on your own
first.
Let us see if you were right:
• A and B are Bb because they produce G (bb)
• If C is BB then D must be Bb or C is Bb then D is BB because H must be Bb to
• produce K (bb)
• J is Bb because G is bb and H is Bb (produced sister K - bb)
• L and M are both Bb because parent J is Bb and I is bb so they cannot be
• homozygous BB AND L and M
• produce a son (N) and daughter (P) that are both homozygous bb
• Offspring O can be either BB or Bb because both parents are
heterozygous Bb
ACTIVITY B
4. Haemophilia is a sex-linked hereditary disease that occurs as a result of a recessive
allele on the X-chromosome. Study the family tree below and answer the questions
that follow:
(Use the symbols H for normal and h for haemophilia above the sex chromosomes, for
example.: XHX h )
pg. 9 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
5. Study the diagram below, which shows three generations of snapdragon plants and
answer the questions which follow. Use the following symbols for the contrasting
alleles: W – for white flowers R – for red flowers
[HINT: you have been told to use W for white flowers. So a homozygous white flower will
be WW. A homozygous red flower will be RR. This means that a heterozygous flower will
be WR. Do NOT use any lower-case letter for the recessive allele because you have been
provided with the symbols for the alleles. ONLY use the W and the R]
5.1 State the kind of dominance shown in the diagram above. (1)
5.2. Use the symbols R and W and write down the genotypes of each of the following
snapdragon plants:
a) A (2)
b) B (2)
c) C (2)
(15)
pg. 10 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
F. Dihybrid Cross
Dihybrid crosses involve two pairs of alleles representing two different characteristics,e.g.:
the height of a plant and the colour of its seeds.
According to the Law of Independent Assortment - The various 'factors' controlling the
different characteristics are separate entities, not influencing each other in any way,
and sorting themselves out independently during gamete formation.
Work through the following example of a dihybrid cross and remember that the alleles for
each characteristic could be either homozygous or heterozygous.
Example of a Dihybrid cross
• In pea plants, the allele for tallness (T) is dominant and the allele for shortness (t) is
recessive. The allele for purple flowers is dominant (P) and the allele for white flowers is
recessive (p). Two plants, heterozygous for both tallness and purple flowers were
crossed.
• Step 1: Decide whether this concerns a monohybrid or a dihybrid cross.
Since two characteristics of each plant are mentioned
(phenotypes: height of plant + colour of flower), it must be a dihybrid cross.
• Step 2: Choose/ use letters to represent the alleles for the gene responsible for each
characteristic.
Let T = the allele for tall plants
Let t = the allele for short plants
Let P = the allele for purple flowers
Let p = the allele for white flowers
• Step 3: Write down the phenotype of the two parents that would be producing gametes.
• tall purple X tall purple (as per question)
pg. 11 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
• Step 5: Show the gametes that each parent produces after meiosis. Each gametemust have
two letters (dihybrid) – one from each characteristic.
N.B. Remember Mendel’s Law of Independent Assortment.
TP Tp tP tp X TP Tp tP tp
Gametes TP Tp tP tp
• Step 7: Determine the phenotypic ratios from the genotypes in the punnet
square.
Phenotypic ratio: 9:3:3:1
If there is one capital letter for the allele in the F1 generation, then that trait (characteristic)
shows in the phenotype; if there are small letters then the recessive trait shows.
pg. 12 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY C
1. Two characteristics of an animal (length of the ears and shape of the lip) were studied.
Each of these characteristics has two variations: Ears may be long or short, and the lip
1.3. A male animal with genotype EELl is crossed with a female animal with genotype
Eell.
a) List all the possible gametes that could be produced by the male animal. (2)
b) Explain how Mendel’s Law of Independent Assortment applies to parents with
EeLl genotypes during gamete formation. (4)
2.1. How do Andrew and Susan’s phenotypes differ from each other? (2)
2.2. List all possible genotypes of the gametes produced by Andrew. (2)
pg. 13 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
G. GENETIC ENGINEERING:
The process where scientists alter, swap or manipulate the genes on the DNA, to
produce a different organism. Genetic engineering involves the transfer of genes
from one organism to an unrelated species.
Diabetics are people who cannot produce their own insulin. Insulin is a hormone
needed to regulate blood sugar. Biochemists have devised a way in which to produce
artificial insulin. A similar process is used to genetically modify many different
organisms. Make sure you know the basic process:
Bacteria produce restriction enzymes that ‘cut’ DNA molecules. These restriction
enzymes are extracted from the bacteria. They don’t need to know restriction
enzymes according to guidelines
pg. 14 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Suggested diagram to explain as above explanation a bit
complicated or use these points to explain
H. CLONING
• With cloning, the nucleus of a somatic cell (2n) of one organism is removed.
• An egg cell (n) is taken from an ovary.
• The nucleus of the egg cell is destroyed.
• The somatic cell’s nucleus (2n) is then placed inside the egg cell.
• The egg cell is put back into a uterus where it is allowed to grow and
differentiate into an embryo.
• When the baby is born, it is identical to the original organism.
• A sheep called Dolly was cloned successfully in 1997.
pg. 15 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
I.STEM CELL RESEARCH:
A stem cell is a cell that has the potential to regenerate multiple cell type tissue and self-
renew so a stem cell is able to produce new cells over a long term by the process of
mitosis.
Once mitosis occurs, the cells are able to differentiate into many different types of
specialized cells and tissue.
Stem cells can be harvested from umbilical cord blood (once a baby has been born), a
foetal blastocyst and bone marrow.
Stem cell therapy can be used to treat a variety of different human diseases:
• cancers like Leukemia
• degenerative diseases like Multiple Sclerosis
• diabetes mellitus where the pancreas no longer produces insulin
• muscle damage
• organ damage and
• certain genetic diseases in conjunction with gene therapy
pg. 16 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Teaching Tool 1: Evidence of Evolution
pg. 17 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
1. Focus on the following definitions.
1.1 Definition of biological evolution:
➢ Biological evolution refers to the change in the characteristics of a species
over time.
pg. 18 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
The distribution of the flightless birds of the world we get ostriches in Africa,
Rhea’s in southern America, Kiwi’s and Emu’s in Australia.
pg. 19 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
2.4. Genetics (evidence for human evolution and evidence for “OUT
OF AFRICA HYPOTHESIS”)
All living organisms share a universal code of three DNA bases (codons) that
are used to specify each amino acid.
Comparison of the human genetic code with that of other organisms shows that
chimpanzees are nearly genetically identical (differ by less than 1.2%) whereas
the mouse differs by ≈15%.
pg. 20 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 1
pg. 21 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Teaching Tool 2:
3 Variation (Causes) (how variation can play a role in natural selection –
variation causes genetic different individuals and that individual may
have an extra characteristics)
➢ Species
A group of organisms that have similar characteristics and can interbreed
to produce fertile offspring
How do you tell if two organisms are the same species:
If a species can interbreed and produce fertile offspring then they are the
same species. If they interbreed but do not produce fertile offspring then they
are not the same species.
pg. 22 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
3.2.1.2 Random arrangement of chromosomes (what is the difference in
variation on crossing over and random arrangement – causes
different genetic gametes)
• Homologous chromosomes are arranged in pairs at the equator during
Metaphase 1 and during Metaphase 2 chromosomes are arranged singly at
the equator.
• This results into genetic different gametes
3.2.2 Mutations
• Gene Mutation – a change in the sequence of nitrogenous bases or nucleotides of
DNA (learners should know the definition)
• Chromosomal mutation – a change in the normal structure or number of
chromosomes (use the correct wording as it comes from the Exam
Guidelines)
3.2.3 Random fertilisation - between different egg cells and different sperm
cells formed by meiosis result in offspring that are different from each other.
(any sperm cell can fertilise the ovum)
3.2.4 Random mating - between organisms within a species leads to a different set of
offspring from each mating pair. (any male can mate with any female)
pg. 23 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
3.3 TYPES OF VARIATION
3.3.1 Continuous variation - (the word range must be emphasized and taught
– light yellow red or dark red)
• When traits do not fall into clear cut classes.
• For example, there is every shade of hair colour between black and blond.
People do not belong to one or other of a small number of distinct categories
i.e. there is continuous variation from one extreme to the other.
• Variations such as these are under genetic control but there are several pairs
of genes involved.
• The genome AA BB CC DD might give black hair while the genome aa bb cc
dd might give blond hair.*
• Genomes Aa Bb Cc Dd or AA Bb CC dd or aa BB cc Dd and all the other
possible combinations would give intermediate colours
• The condition of having more than one gene controlling a characteristic is
called polygenic inheritance (polygenic inheritance is not for exams)
Discontinuous variation e.g. Mendel’s pea plants either tall or short and had no
intermediate forms between these traits
• You are either male or female, there are no intermediates
• Your ABO blood group is either A, B, AB or O
• Easily distinguishable and not affected by environmental conditions
• Brought about by one or two genes
• Genetic defects such as colour blindness, albinism, sickle cell anaemia are
all genetically controlled in a discontinuous way
• You either have these conditions or you do not.
• There are no intermediate states
pg. 24 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Discontinuous variation in blood group. The figures cannot be made to fit a smooth
curve because there are no intermediates.
ACTIVITY 2
2.3.1. Complete the table below on the differences between continuous and
discontinuous variation.
pg. 25 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
3 The graph below illustrated different hights in humans.
(5)
3.1.1 What type of variations is illustrated in this graph (1)
pg. 26 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Teaching Tool 3:
ORIGIN OF AN IDEA (Evolution theories)
pg. 27 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
4.1 Ideas on Evolution
pg. 28 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
5.1. Jean Baptiste de Lamarck – 1744-1829 (Lamarckism) (learners have
to know how to spell it)
1. Law of use and disuse (explain the theory – firstly they must state the law
and explain the law)
• Changes in the environment create new needs that cause organisms to
modify their existing organs to meet the need.
• Repeated use of the organ would cause it to enlarge and become more
efficient. Disuse of an organ would cause it to degenerate.
2. Law of inheritance (explain the theory – firstly they must state the law and
explain the law)
What happened to this new The long necks acquired in this way
characteristic? could be passed on to the next
generation /were inherited
What was the result of this? All the giraffes have long necks
(no longer a general statement - learners must state the favorable
characteristics)
Example:
Refer to the characteristic (Long necks) – do not only state - “the acquired
characteristic was pass on to the next generation”
pg. 29 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
6.1 Darwinism (Charles Darwin – 1809–1882)
6.1.1 Darwin's theory of evolution by natural selection:
Note the difference how to answer this from previous years on how to
describe Darwinism
How to describe Darwinism
Example:
pg. 30 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Guiding Question Darwin’s explanation
1-State the characteristic that varies There is a variation in the 1- length of
giraffe’s necks.
Describe the 2- variations There were giraffes with 2- long neck and
short necks
3- Explain the environmental change/ Leaves/ food was only available a the top of
selection pressure for natural selection the tree/higher trees and natural selection
(what is causing natural selection) took place between giraffes with long necks
and short necks for food
4- State the unfavorable characteristic and Giraffes with 4- short necks (unfavourable
why it is unfavorable characteristic) could not get food from the top
of a tree/higher trees, 4- 4- their neck was too
short
State the favorable characteristic and why Giraffes with long necks (favourable
it is favorable characteristic) could get food from the top of a
tree/higher trees, their neck was long enough
Explain what happen to this individual with They could eat more leaves/food and survive
the favorable characteristics
What happen to the favorable The giraffes with the long necks reproduce
characteristic
The allele for long necks will be passed on to
the offspring
pg. 31 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
6.1.2 Difference between Lamarck and Darwin
Lamarck’s Darwin’s
ACTIVITY 3
Brine shrimp are small arthropods found in saltwater lakes. During favourable conditions
female shrimps produce eggs that hatch into live young. However, when conditions are
unfavourable, the shrimp produce cysts. Each cyst contains the embryo covered with a
hard, protective covering. In this state the embryo stops growing and is said to be dormant.
The embryo can remain in this dormant state for many years and the cyst will only hatch at
the optimum salt concentration.
Scientists wanted to investigate which salt concentration resulted in the highest percentage
of hatched cysts
They did the following:
• Prepared salt solutions of different concentrations: 0%, 0,5%, 1%, 1,5% and 2%
• Placed 30 mℓ of each solution into one of five beakers
• Took samples of brine shrimp cysts using a dropper
• Counted the number of cysts in each sample
• Recorded this as the initial number of cysts
• Placed the samples into each of the five beakers
• Left the beakers at room temperature for 48 hours
• Recorded the number of cysts that hatched in each beaker
• Calculated the percentage of cysts that hatched.
• The results are shown in the table below.
pg. 32 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
3.1. State TWO planning steps to consider before collecting the samples. (2)
3.3 Calculate the value of X in the table. Show ALL working. (3)
3.4 State THREE factors that were kept constant in order to ensure the validity
of this investigation. (3)
ACTIVITY 4
4.1. There are two variations in the colour of kingsnakes. Some have a bright
colourful pattern and others have a dull pattern. Kingsnakes are non-poisonous
to their predators. Coral snakes also have a bright colour pattern but are
poisonous to their predators. This is a defence mechanism as predators avoid
them. Scientists observed that where kingsnakes shared the same habitat with
coral snakes, there were more kingsnakes that had bright colourful patterns.
The diagram below represents the distribution of the snakes.
pg. 33 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
4.1.1. Explain how the bright colour pattern of coral snakes influences their survival. (3)
4.1.2. Use Darwin's theory of evolution through natural selection to explain why
there are more brightly coloured kingsnakes in this habitat. (6)
ACTIVITY 5
5.1. Flightless bird species that are currently distributed across different continents
are shown in the picture below.
Scientists hypothesise that these species of flightless birds arose from a single
common ancestor that was able to fly.
pg. 34 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 6
Darwin and Lamarck were both scientists who tried to understand evolution.
Lamarck’s theory of evolution was based around how organisms (e.g. animals, plants)
change during their lifetime, and then pass these changes onto their offspring. For
example, Lamarck believes that the giraffe had a long neck because its neck grew longer
during its lifetime, as it stretched to reach leaves in high-up trees, meaning that each
generation of giraffe had a longer neck than previous generations.
6.1. Give:
a) The term that describes Lamarck’s ideas. (1)
b) The term that describes Darwin’s idea of Natural selection. (1)
c) The name of the Scientist that is associated with the theory of punctuated
equilibrium. (1)
6.2. Tabulate the difference between Lamarck’s theory of evolutions and Darwin’s
theory of evolution (2)
6.3. Explain whose idea evolution is more acceptable today. (2)
pg. 35 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
7.1 Punctuated Equilibrium (Eldredge and Gould – 1972) (Learners must
know who came up with this theory)
• Stephan J Gould and Niles Eldredge formulated this model (1972).
• They observed that the fossil record gives a different picture of evolution.
• They claim that there were long periods of stasis (4-10 million years)
involving little evolutionary change.
• Then occasional rapid formation of new species (5,000 - 50,000 years).
• Punctuated Equilibrium explains the speed at which evolution takes place:
• Evolution involves long periods of time where species do not change or
change gradually through natural selection (known as equilibrium).
➢ This alternates with (is punctuated by) short periods of time where rapid
changes occur through natural selection.
➢ during which new species may form in a short period of time.
pg. 36 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Stasis
(Equilibrium)
Rapid change
(Punctuated
pg. 37 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
8.1. Artificial selection
pg. 38 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Teaching Tool 4
Natural selection VS Artificial selection
Natural selection Artificial selection
Environment is the selective force Human is the selective force
Response is adaptation to nature Response to satisfy human need
Happens in a species Can include more than one species
Example Artificial
Selection
pg. 39 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
4.2. List similarities between natural selection and artificial selection.
• both create a trend towards organisms better suited for their environment
‘purpose’
• both natural selection and artificial selection involve an organism’s traits being
determined by how much they are favoured
• then, the organisms with favourable traits pass those traits on to future
generations both processes eventually form a new species.
ACTIVITY 7
All types of domestic dogs are capable of interbreeding to produce puppies which will
eventually be capable of interbreeding with any other domestic dog
7.3.1. Explain why all breeds of domestic dogs belong to the same species (2)
7.3.2. Domestic dogs are bred to show specific characteristics with respect to their
health, personality, and appearance. Explain why this is consider as artificial
selections. (2)
7.3.3. Describe how artificial selection led to different breeds of domestic dogs (3)
7.3.4. What effect does the type of selection mentioned in 7.3.3 have on the survival
change of the dog species. (2)
pg. 40 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Teaching Tool 5: Speciation
• such that the individuals of the two populations become very different from each
other
• The BOLD is the fact that you state according to the exam guidelines
• The highlight is what you must get out of the example in the exam paper.
pg. 41 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
If a population of a single species/original population
(Mention the original species in the extract that they give you and refer to where the
species lived)
such that the individuals of the two populations become very different from
each other
The two populations are now different species, name the new species. (mention
the new species that form)
pg. 42 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Example 1
Pottos and lemurs are small mammals. Scientists believe that pottos and lemurs
share a common ancestor that existed in Africa. Presently pottos only occur in Africa
while lemurs are only found in Madagascar. Madagascar is an island off the East
coast of Africa as shown in the diagram below.
pg. 43 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
• There is now no gene flow between the
• (Mention how many populations are there now)
• There is now gene flow between the two population in Africa and
Madagascar
• such that the individuals of the two populations become very different
from each other
• Even if the two populations of Africa and Madagascar were to mix again
• they will not be able to interbreed.
• The two populations are now different species, Pottos and Lemurs
pg. 44 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Example 2:
The present-day distribution of three closely related species of the dog family, the
coyote, jackal and dingo, is shown on the world map below.
• The three populations are now different species, Coyote, Jackal and Dingo
pg. 45 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 8
8.1.
8.1.2. Describe how speciation of the GRAND CANYON squirrels took place. (5)
pg. 46 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 9
9.1. Darwin discovered two different species of tortoises on two different islands
in the Galapagos. One had a domed shell and short neck, the other had an
elongated shell and a longer neck. The two islands had very different
vegetation. One of the islands (island X) was rather barren, dry and arid. It
had no grass but rather short tree-like cactus plants. On the other island
(island Y), there were no cactus plants but it had a good supply of water and
grass grew freely. The diagram below shows the two main???
9.2.2. Describe how the two tortoise species become different (6)
9.2.3. List FOUR sources of variation that could have led to the variation in the (4)
tortoise population
9.2.4. Explain the role of natural selection on island X where more of tortoise 2 are
found. (6)
pg. 47 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Teaching Tool 6: Reproductive isolation mechanisms
pg. 48 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
10.3 Plant adaptation to different pollinators
Many plants and their flowers are specifically adapted for specific pollinators.
Some closely related species of plants have different characteristics such as
flower shape, size, colour, reward type (nectar or pollen), scent and timing of
flowering all play a role in attracted certain pollinators to them.
Also, cross-pollination between the different species is prevented.
pg. 49 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
10.4 Infertile offspring
Even if two species are able to physically mate and produce offspring, they will
still be reproductively isolated due to the fact the most hybrid offspring are
infertile.
(The genital opening of these snails are not aligned, and mating cannot be
completed)
pg. 50 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 10
10.1. Identify the reproductive isolation mechanisms hat is illustrated in the (5)
diagrams below.
May
Species 1 Species 2
pg. 51 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Sheep and goat hybrid dies before birth
ACTIVITY 11
pg. 52 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
(1)
11.2.3. Explain the development of infertile offspring between two species. (3)
pg. 53 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
pg. 54 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
11. Evolution in present times
Teaching Tool 7 Evolution in present times
Evolution is always happening. Most of the time it is impossible to observe changes in
populations and species because evolution happens very slowly – thus the theory of
gradualism. However, there are some cases (e.g.: rapidly producing organisms such
as viruses and bacteria) that allow scientists to study how species change in response
to environmental factors. Pathogens (viruses and bacteria) evolve quickly because
there is lots of natural variation amongst them and the fact that mutations occur most
often in rapidly reproducing organisms.
The evolution of drug resistance in bacteria
Low --------------------->High
pg. 55 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 12
a) A (1)
b) B (1)
12.1.4 Explain how these two dark mosquitoes evolved in the first generation (3)
12.1.5 Describe the composition of the survivors of the second pesticide application (2)
pg. 56 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
12. Evidence for common ancestors
Teaching Tool 8 - The place of humans in the phylogenetic tree
Human Evolution
The place of the family Hominidae in the animal kingdom
Hominidae is the family name for all primates including all African Apes
• Humas are mammals and belong to the class MAMMALIA, because their bodies
is covered with hair and they suckle their young
• The order they belong to is PRIMATES. - Primates includes human, apes,
orangutangs, gorillas an chimpanzees
pg. 57 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
• The Family HOMINIDAE includes HOMINIDS
HOMININS
Great Apes HOMINIDS (refers to bipedalism)
(bipedal)
Orangutan
Ardipithecus
Gorilla
Australopithecus
Chimpanzee
Homo
Hominids refer to the modern and extinct Great apes (i.e. modern humans,
chimpanzees, orangutans and all their immediate ancestors)
Great Apes is also referring to as African Apes
Hominin – the group consisting of modern humans , extinct human species and
all our immediate ancestors (including members of the genera Homo,
Australopithecus and Ardipithecus). Are all bipedal organisms.
Ardipithecus, Australopithecus and early Homo- species are considered fossil
ancestors of modern humans (learners must know this line of development)
Modern Humans are classified in the genus and species – Homo sapiens
Homo – sapiens
Genus – Homo
Specie- sapiens
# The genus name and species name must be underlined / cursive #
# Read what the question asks – Give the Genus, species, family, class or
order name
pg. 58 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
How to interpretate a Phylogenetic tree:
• The root of the phylogenetic diagram represents the ancestor, and the tips of the
branches, the descendants of that ancestor. To move upwards is to move forward
in time.
(3 and 4 are more related to each other because there we have a more recent
common ancestor)
• Each lineage has a part of its history that is unique and parts that are shared with
other lineages, as illustrated below …
pg. 59 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
• And each lineage has ancestors that are unique to that lineage and
common ancestors that are shared with other lineages.
ACTIVITY 13
Present
Homo sapiens
Time (million years ago)
Homo erectus
Australopithecus robustus
Australopithecus boisei
Homo habilis
Australopithecus
africanus Australopithecus afarensis
pg. 60 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
13.1.2 How many of each of the following are represented in the
diagram?
a) Genera
b) Species (2)
pg. 61 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
1. Upright posture: the back limbs of hominids are generally stronger
than their front limbs, enabling them to stand erect (upright) and use
their hands for grasping; standing erect also gives a better view of
surroundings and exposure of genitals to attract the opposite sex
2. Large brains: relative to their body size, hominids have larger brains
than other species in the Animal Kingdom. This allows them to process
and store information.
3. Long upper arms / front limbs: apes are normally quadrupeds, and this
requires longer front limbs. Longer front limbs also make it easier to grasp and
swing from branches.
4. Two eyes in the front of the head, this provides good binocular vision as
both eyes work together.
5. The eyes have cones for colour vision that gives greater clarity.
7. Freely rotating arms: arms can be lifted above the head to swing from
branch to branch, or to pick fruit hanging relatively high above the ground.
(learners must also know the significance of this characteristic)
8. Elbow joints allowing rotation of forearm this allows the limb to extend or
flex to grasp and reach for objects. It also enables the flexing and rotation of
the wrists
9. Bare fingertips or nails instead of claws: Digits (finger and toes) have soft,
broad, and very sensitive pads. The flat fingernails or toenails protect these
pads.
14. Parts of the brain that process information from the hands and eyes are
enlarged
pg. 62 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Correct way to state Incorrect way
Large brain relative to body size Not just large brain- elephants have large brain
too
Two eyes in front of the head Two eyes
Long upper arms Long arms
Upright posture Can stand up straight
Two teats/nipples Two mammal glands
Freely rotating arms Rotating arms
Elbow joints allowing rotation of Elbow rotate
forearm
ACTIVITY 13
pg. 63 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
13.1.4. Which organism: (1)
a) Belongs to the hominin group
b) Is quadrupedal
c) Belongs to Mammalia
13.1.6. Give any other similarities that you did not mention in 1.2
Anatomical differences between Africa apes and humans (also emphasis the
significance)
pg. 64 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Differences between Homo sapiens and other primates
4. Brow ridges are not well developed 4. Brow ridges are well developed
5. Smaller canines 5. Larger canines
6. Smaller spaces/diastema between the 6. Larger spaces/diastema between the
teeth teeth
7. Jaws with teeth on a gentle/round curve/C - 7. Jaws with teeth in a rectangular/U
shape shape
8. Jaws 8. Jaws
None – prognathous/ prognathous/
Less protruding jaw More protruding jaw
9. Lower jaw has a well-developed chin 9. Lower jaw has poorly developed chin
10. No cranial ridge 10. Cranial ridges at the top of the cranium
11. Spine more curve/ S- shape 11. Less curve/ C- Shape
12. Pelvic gridle short and wide 12. Pelvic gridle long and narrow
13. Palate small and round 13. Palate long and rectangular
pg. 65 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
(visible features)
Mistakes made when answering anatomical differences/ visible differences
Foramen magnum
pg. 66 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Lower jaw has a well-developed chin or
poorly develop chin (number 6)
In Humans Prognathous
None – prognathous OR
OR More protruding
Less protruding
Teeth
Not:
pg. 67 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
The significance of the structural changes that characterise the evolution of
modern humans
Structure Significance
Structure Significance
pg. 68 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Dentition/Teeth
• This corresponds with the decreased
In ape-like beings there are gaps/diastema need to bite and tear
between incisors and canines • and an increased need to grind and
but no gaps between the teeth in humans chew in humans
Humans have smaller canines than the ape- • in view of the change in diet to soft,
like beings cooked food
Humans have flatter molars and pre-molars
than the ape-like beings
Chin • Developed chin assists with speech in
humans
In humans the chin is more developed
compared to the ape-like beings
pg. 69 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 14
a) Hominidae
b) Hominin
c) Bipedal organism (3)
14.3. Explain how the change in the skull from B to C could indicate (4)
change in intelligence
14.4 Tabulate FIVE visible differences between the skulls of A and C (2)
(20)
pg. 70 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
2. Out of Africa Theory
Teaching tool 10: The out of Africa Hypothesis
Modern humans originated in Africa and then migrated to other continents.
Information on each of the following fossils that serve as evidence for the
It must be explained as stated here
'Out-of-Africa' hypothesis:
o Ardipithecus fossils found in Africa only
o Australopithecus fossils found in Africa only (Karabo, Little Foot, Taung
Child, Mrs Ples)
o Homo -fossils -
- Homo habilis found in Africa only
- Oldest fossils of Homo erectus and Homo sapiens found in Africa,
- Younger fossils were found in other parts of the world)
pg. 71 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Evidence from fossils of different ages show that the anatomical characteristics of
organisms changed gradually over time.
# It is very important to know the line of fossil evidence and the fossils that is
used as reference (where they are found, who discovered them etc.)
pg. 72 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Homo sapiens (modern humans of today)
The table below shows the characteristics of different organisms (as obtained from a
study of their fossils) that are thought to be in the same lineated to the evolution of
modern humans.
The fossils are dealt with in the order in which they appeared on earth.
(the characteristics will be given to learners, but learner must know who
discovered the fossil)
pg. 73 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Organism When Fossil site discover Characteristics
organi ed by
Ardipithecu 5–4
smmya North-East Tim White Brain size: 300–350ml
s ramidus existed Ethiopia Forward position of foramen
(Ardi) magnum Very prognathous
(more protruding jaws) Heavy
brow ridges
Pelvis structure: bipedal and
tree climbing
Australopithecu 4 – 2,7 mya Ethiopia, Donald Brain size: 375–550ml
s afarensis Kenya, Johans Forward position of
(Lucy) Tanzania on foramen magnum Very
prognathous
Heavy brow ridges
Canines large and
pointed
Long arms.
No cranial ridge
Homo habilis 2,2 – 1,6 Tanzania Louis and Brain size: 650 ml Less
mya Mary prognathous
Leakey Less pronounced brow ridges
Human-like teeth – smaller
canines. Long arms
pg. 74 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
Homo erectus 2 – 0,4 Java in Eugene Brain size: 900 ml Prognathous
mya Indonesia Dubois Cranial ridges Short canines
and then Longer legs and shorter arms
Swartkrans
Homo sapiens 200 000 Makapansgat Tim White Brain size: 1200–1800 ml No
years ago in Limpopo; brow ridges
– present Border Cave Small teeth Short arms
in KZN;
Blombos
Cave in the
Western Cape
Given the amount of genetic material shared between humans and other
hominids (the apes), they must have had a common ancestor who lived
approximately 5 – 6 million years ago.
pg. 75 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
13.1.3 Cultural evidence: toolmaking
• A very important aspect of human evolution, separating humans from other
hominids, is the development and use of tools.
• Art also contributed. The earliest known art dates from about 100 000 years
ago, and the earliest cave paintings (see Figure 26 below), of which we have
an abundance in South Africa, were made some 40 000 years ago
pg. 76 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
ACTIVITY 15
15.1 .1 Name the TWO lines of evidence for human evolution that is
referred to in the extract above (2)
15.1.4 Describe ONE feature of the skull that can be used as evidence (2)
for bipedalism
15.1.5 State TWO similarities between the hands of African apes and (3)
modern humans.
15.1.7 Draw a table to show the brain volumes of the different Homo (4)
species, using information from the extract.
pg. 77 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
15.2. Scientists use fossils as evidence for human evolution. The
brain volume of some extinct primates has been estimated from
their fossils and have been compared to the brain volumes of
living primates
15.2.1. What type of evidence of human evolution is given in the table (1)
15.2.6 Draw a bar graph to show the average brain volume of EACH
of the species of the genus Homo. (6)
pg. 78 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
15.2.7 Explain how genetic evidence as a line of evidence contributes
to human evolution.
ACTIVITY 16
16.1.3 If asked to decide whether a complete skull with jaw- bones was (8)
that of Ardipithecus or Australopithecus, describe what four
features would you examine
pg. 79 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP
16.2.2. Give the name of the Australopithecus afarensis that was found
in Kenya and Tanzania
We would like to express our profound gratitude to the following bodies for their
contributions to the compilation of this Content Manual for Winter Classes.
pg. 80 LIFE SCIENCES: EVOLUTION GRADE 12 CONTENT MANUAL TEACHER/LEARNER: ADAPTED BY L. MONYANE, Z.SANDA & R.BISHOP