Cortical Blood Vessels
Microanatomy of Blood Vessels
Cerebral Arteries and Veins
Henri Duvernoy‘s Seminal Paper
on Cortical Blood Vessels
Human Blood
Circulation
Blood Vessel Walls - Microanatomy
Blood Vessel Types
Elastic Artery (Aorta and Large Branches)
Orcein (Elastika-Färbung)
Vein – Muscular Artery
Resorcin-Fuchsin
(Elastika-Färbung)
Vein – Muscular Artery
HE
Arteriole – Venule
HE
Capillaries
HE
Capillaries
Capillary Types
Endothelium Endothelium with
without fenestrations and pinocytotic activity
uninterrupted basement (lung, heart, skeletal muscle,
membrane (CNS) connective tissue, skin)
Endothelium with fenestrations Endothelium with fenestrations
occupied by a diaphragm without a diaphragm
(gut, endocrine glands) (liver, kidney)
End or Terminal Arteries (Brain, Retina, Heart, Liver, Kidney)
Macroanatomy: Internal Carotid & Vertebral Artery
Macroanatomy: Basilar Artery & Circle of Willis
Macroanatomy: Middle Cerebral Artery
Macroanatomy: Middle Cerebral Artery
Macroanatomy: Anterior & Posterior Cerebral Artery
Macroanatomy: Vascular Territories of the 3 Arteries
The Gap
??
Macroanatomy: Superficial Veins
Macroanatomy: Superficial Veins
Macroanatomy: Deep Veins
Macroanatomy: Dural Venous Sinuses
Macroanatomy: Dural Venous Sinuses
Macroanatomy: Dural Venous Sinuses
Henri M. Duvernoy: Cortical Blood Vessels (1981)
Henri M. Duvernoy: Cortical Blood Vessels (1981)
Cited 383 times since its publication (as of 10.2017)
Techniques for Studying Vascularization
Intravascular injection of india ink or gelatin ("Injektionspräparate")
Injection Fixation of tissue
(a) Cutting (thick paraffin sections, 400 µm) Tissue clearing
(Spalteholz) Light microscope
(b) Uncut tissue block Stereomicroscope (for surface vessels)
Intravascular injection of polymerizing agents ("Korrosionspräparate")
Injection of methyl methacrylate (Mercox) Tissue destruction
(potassium hydroxide) Cast of cortical vessels
(a) Stereomicroscope
(b) Scanning electron microscope (SEM)
Cortical Pial Vessels (Medial Orbital Gyrus)
Cast of Pial Arterioles (SEM)
Principal Groups of Intracortical Arteries and Veins
Typical Intracortical Artery and Vein (Group 4)
All Groups of Arteries and Veins
Vascular Layers
Differences between Cortical Areas – Cytoarchitecture
Geyer et al.
NeuroImage
1999
Differences between Cortical Areas – Cyto Variability
Differences between Cortical Areas – Ligand Binding Sites
Geyer et al.
Nature 1996
Differences
between
Cortical Areas
– Vasculature
Central
Sulcus
Differences between Cortical Areas – Cyto Variability
Brain #16/96 Brain #207/84
Left Hemisphere Left Hemisphere
POS POS
CALS
CALS
Area 17
Area 18
CALS: Calcarine Sulcus
POS: Parieto-Occipital Sulcus
Amunts et al.
NeuroImage 2000
Differences
between
Cortical Areas
– Vasculature
Calcarine
Sulcus
