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BP 601t Medicinal Chemistry 3 Jun 2020

Previous Year Question Paper of B.Pharmacy 6th Semester

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Aditya Kumar
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32 views3 pages

BP 601t Medicinal Chemistry 3 Jun 2020

Previous Year Question Paper of B.Pharmacy 6th Semester

Uploaded by

Aditya Kumar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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com

Total No. of Questions : 8] [1] [Total No. of Printed Pages : 3

Roll No ..................................
BP-601T/PY-601-CBGS
B.Pharmacy VI Semester (PCI Scheme)/
(Non-PCI Scheme)
Examination, June 2020
Choice Based Grading System (CBGS)
Medicinal Chemistry-III
Time : Three Hours
Maximum Marks : 75
Note: i) Attempt any five questions.
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ii) All questions carry equal marks.
g^r àíZm| Ho$ g_mZ A§H$ h¡&
iii) In case of any doubt or dispute the English version
question should be treated as final.
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o« r ^mfm
Ho$ àíZ H$mo A§{V‘ ‘mZm Om¶oJm&
1. Define β-lactam antibiotic. Give historical background,
Stereochemistry, SAR and degradation of penicillin groups
of antibiotics.
β-b¡³Q>‘ E§Q>r~m¶mo{Q>H$ H$mo n[a^m{fV H$a|& Eo{Vhm{gH$ n¥ð>^y{‘,
ñQ>o[a¶moHo${‘ñQ´>r, Eg E Ama Am¡a E§Q>r~m¶moQ>rH$ XdmAm| Ho$ no{Z{g{bZ
g‘yhm| H$m jaU H$a|&
2. What are MDR TB and XDR TB? Give the classification of
anti-tubercular drugs. Write synthesis of Para amino salicylic
acid.
E‘ S>r Ama Q>r ~r Am¡a E³g S>r Ama Q>r ~r ³¶m h¢? E§Q>² r-Q>ç~y aHw$ba XdmAm|
H$m dJuH$aU X|& n¡am A‘rZmo g¡{b{g{bH$ E{gS> H$m g§íbofU {bI|&
BP-601T/PY-601-CBGS PTO

https://www.rgpvonline.com
https://www.rgpvonline.com

[2]

3. Define and classify Antiviral agent with suitable examples. Give


the method synthesis and mechanism of action of Acyclovir.
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H$a|& EgmB³bmo{da H$s {H«$¶m H$s {d{Y g§íbofU Am¡a V§Ì X|&
4. Explain life cycle of Malarial parasite and drug acting on each
stage of life cycle. Write brief note on quinolines as
antimalarial agents. Outline synthesis of chloroquine.
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Ho$ OrdZ MH«$ H$s ì¶m»¶m H$a|& E§Q>r‘bo[a¶b EO|Q> Ho$ ê$n ‘| {³dZmo{bZ
na g§{jßV ZmoQ> {bI|& ³bmoamo³drZ Ho$ g§íbofU H$mo aoIm§{H$V H$a|&
5. What are sulfonamide antibiotics? Write different ways to
classify sulphonamides. Write synthesis and mechanism of
action of sulfamethoxazole.
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Ho$ {bE {d{^Þ VarHo$ {bI|& gë’¡$‘oWmo³gmμOmob H$s {H«$¶m Ho$ g§íbofU
Am¡a V§Ì H$mo {bI|&
6. Discuss classification, Structure Activity Relationship and
Mechanism of Action of antifungal agents with suitable
examples.
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g§~§Y Am¡a V§Ì H$s MMm© H$a|&
7. Write synthesis, mechanism of action and uses of (any three)
a) Miconazole
b) Chloramphenicol
c) Isoniazid
d) Trimethoprim
e) Dapsone

BP-601T/PY-601-CBGS PTO
Contd...

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https://www.rgpvonline.com

[3]

g§íbofU, H$ma©dmB© H$m V§Ì Am¡a Cn¶moJ H$mo {bI|& (H$moB© VrZ)
A) ‘m¶H$moZmμOmob
~) ³bmoa‘’o${ZH$b
g) AmBgmo{Z¶m{OS>
X) Q´>mB©{‘Wmoàr‘
B) S>n¡ gmoZ
8. Write short note on any three of the following.
a) Mechanism of action and SAR of Tetracyclines
b) Solid phase and solution phase synthesis
c) Quinolones with suitable examples
d) Parameters used in drug design
e) Third and fourth generation cephalosporins
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A) Q>oQ´>mgmB{³bZ H$s {H«$¶m H$m V§Ì Am¡a Eg E Ama
~) gm°{bS> ’o$O Am¡a gbyeZ ’o$O g§íbofU
g) Cn¶w³V CXmhaU Ho$ gmW {³dZmobmoZ
X) Xdm {S>μOmBZ ‘| Cn¶moJ {H$E OmZo dmbo n¡am‘rQ>a
B) Vrgar Am¡a Mm¡Wr nrT>r Ho$ go’$bmoñnmo[aZ
******

BP-601T/PY-601-CBGS PTO

https://www.rgpvonline.com

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