What Is Autism?
What Is Autism?
Autism, also called autism spectrum disorder (ASD), is a complicated, lifelong condition that
includes problems with communication and behavior. It's a spectrum disorder, which means it
affects people in different ways and in varying degrees. It usually appears by age 2 or 3.
People with autism have trouble with communication. They have trouble understanding what
other people think and feel. This makes it hard for them to express themselves, either with words
or through gestures, facial expressions, and touch.
People with autism may have problems with learning. Their skills might develop unevenly. For
example, they could have trouble communicating but be unusually good at art, music, math, or
things that involve memory. Because of this, they might do especially well on tests of analysis or
problem-solving.
More children are diagnosed with autism now than ever before. But the latest numbers could be
higher because of changes in how it’s diagnosed, not because more children have the disorder.
Social communication and interaction skills can be challenging for people with ASD.
Examples of social communication and social interaction characteristics related to ASD can
include
● Avoids or does not keep eye contact
● Does not respond to name by 9 months of age
● Does not show facial expressions such as happy, sad, angry, and surprised by 9 months of
age
● Does not play simple interactive games like pat-a-cake by 12 months of age
● Uses few or no gestures by 12 months of age (for example, does not wave goodbye)
● Does not share interests with others by 15 months of age (for example, shows you an
object that they like)
● Does not point to show you something interesting by 18 months of age
● Does not notice when others are hurt or upset by 24 months (2 years) of age
● Does not notice other children and join them in play by 36 months (3 years) of age
● Does not pretend to be something else, like a teacher or superhero, during play by 48
months (4 years) of age
● Does not sing, dance, or act for you by 60 months (5 years) of age
Genetic factors
Over the last few decades, there has been a significant increase
in autism genetics research. During that time, scientists have found that ASD is highly heritable.
This means that genetics play a large role in its development.
For example, a 2019 study
of more than 2 million people across five countries estimated ASD’s heritability to be
approximately 80%.
Researchers have also found that specific gene variants can contribute to autism risk. A gene
variant is a permanent change in the DNA sequence that makes up a gene. Some gene variants
come from a person’s parents, while others can occur during a person’s lifetime.
There is no clinical reason to carry out routine testing for common gene variants, as many people
have them, and they do not reliably predict that a person will be autistic.
However, there is a growing number of rare gene variants that doctors could look for. Testing for
them could potentially
:
● give people a better understanding of why they, or their child, is autistic
● enhance early recognition, allowing people to gain support sooner
● increase the quality of healthcare a person receives
However, genetic testing also comes with some potential difficulties, including:
● Difficulty interpreting findings: The rare gene variants that have links to autism are not a
guarantee a person will be autistic nor a way to predict the severity of symptoms.
● False negatives: This can happen if a doctor fails to detect a known variant. This may
mean a child does not receive a correct diagnosis.
● Ethical concerns: There are significant fears among members of the autistic community
that scientists could use genetic testing for autism as a first step toward erasing it. This is
known as eugenics.
Environmental factors
Researchers have identified several environmental factors
that may play a role in developing autism, including:
● bacterial and viral infections while pregnant
● maternal autoimmunity
● the use of certain medications during pregnancy (e.g., valproic acid, selective serotonin
reuptake inhibitors)
● environmental toxicants, including air pollution, heavy metals, and pesticides
● maternal obesity or diabetes
parental age at the time of conception
● extremely preterm birth and low birth weight
● extremely preterm birth and low birth weight
It is important to note that some studies on these factors have somewhat confusing results.
For example, an older 2010 study from Denmark found no association between maternal
infection and ASD diagnosis when looking at the total period of pregnancy.
However, researchers did find an association between ASD diagnosis and pregnant people who
were admitted to the hospital for viral infections during the first trimester and pregnant people
who had bacterial infections in the second trimester.
Similarly, in 2012
, a study found “little evidence” of an association between ASD and common infectious diseases
or fevers during pregnancy. However, it did find an increased risk of an ASD diagnosis if a parent
had influenza (flu) or prolonged fever during their pregnancy.
More research is necessary to better understand the role that environmental factors might play.
Treatment
No cure exists for autism spectrum disorder, and there is no one-size-fits-all treatment. The goal
of treatment is to maximize your child's ability to function by reducing autism spectrum disorder
symptoms and supporting development and learning. Early intervention during the preschool
years can help your child learn critical social, communication, functional and behavioral skills.
The range of home-based and school-based treatments and interventions for autism spectrum
disorder can be overwhelming, and your child's needs may change over time. Your health care
provider can recommend options and help identify resources in your area.
If your child is diagnosed with autism spectrum disorder, talk to experts about creating a
treatment strategy and build a team of professionals to meet your child's needs.
Treatment options may include:
● Behavior and communication therapies. Many programs address the range of social,
language and behavioral difficulties associated with autism spectrum disorder. Some
programs focus on reducing problem behaviors and teaching new skills. Other programs
focus on teaching children how to act in social situations or communicate better with
others. Applied behavior analysis (ABA) can help children learn new skills and generalize
these skills to multiple situations through a reward-based motivation system.
● Educational therapies. Children with autism spectrum disorder often respond well to highly
structured educational programs. Successful programs typically include a team of
specialists and a variety of activities to improve social skills, communication and behavior.
Preschool children who receive intensive, individualized behavioral interventions often
show good progress.
● Family therapies. Parents and other family members can learn how to play and interact
with their children in ways that promote social interaction skills, manage problem
behaviors, and teach daily living skills and communication.
● Other therapies. Depending on your child's needs, speech therapy to improve
communication skills, occupational therapy to teach activities of daily living, and physical
therapy to improve movement and balance may be beneficial. A psychologist can
recommend ways to address problem behavior.
● Medications. No medication can improve the core signs of autism spectrum disorder, but
● Medications. No medication can improve the core signs of autism spectrum disorder, but
specific medications can help control symptoms. For example, certain medications may be
prescribed if your child is hyperactive; antipsychotic drugs are sometimes used to treat
severe behavioral problems; and antidepressants may be prescribed for anxiety. Keep all
health care providers updated on any medications or supplements your child is taking.
Some medications and supplements can interact, causing dangerous side effects.
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