Comprehensive Body Lab Report
Comprehensive Body Lab Report
HAEMATOLOGY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Comment:
Interpretation: HbA1c%
≤5.6 Normal
5.7-6.4 At Risk For Diabetes
≥6.5 Diabetes
Comments:
A 3 to 6 monthly monitoring is recommended in diabetics. People with diabetes should get the test done more often if their blood
sugar stays too high or if their healthcare provider makes any change in the treatment plan. HbA1c concentration represent the
integrated values for blood glucose over the preceding 8-12 weeks and is not affected by daily glucose fluctuation, exercise &
recent food intake.
Please note, Glycemic goal should be individualized based on duration of diabetes, age/life expectancy, comorbid conditions,
known CVD or advanced microvascular complications, hypoglycemia unawareness, and individual patient considerations.
Factors that interfere with HbA1c Measurement: Hemoglobin variants, elevated fetal hemoglobin (HbF) and chemically modified
derivatives of hemoglobin (e.g. carbamylated Hb in patients with renal failure) can affect the accuracy of HbA1c measurements.
Factors that affect interpretation of HbA1c Measurement: Any condition that shortens erythrocyte survival or decrease mean
erythrocyte age (e. g., recovery from acute blood loss, hemolytic anemia, HbSS, HbCC, and HbSC) will falsely lower HbA1c test
results regardless of the assay method used. Iron deficiency anemia is associated with higher HbA1c.
Note: Presence of Hemoglobin variants and/or conditions that affect red cell turnover must be considered, particularly when the
HbA1c result does not correlate with the patient's blood glucose levels.
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HAEMATOLOGY
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Test Name Result Unit Bio. Ref. Interval Method
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HAEMATOLOGY
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Test Name Result Unit Bio. Ref. Interval Method
/Microscopy
MPV 9.9 fl 6.5 - 12 Calculated
PDW 17 fl 9 - 17 Calculated
Comment:
As per the recommendation of International council for Standardization in Hematology, the differential leucocyte counts
are additionally being reported as absolute numbers of each cell in per unit volume of blood.
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HAEMATOLOGY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Comment:
ESR provides an index of progress of the disease and is widely used as an indicator of inflammation, infection, trauma, or
malignant diseases. Changes are more significant than a single abnormal test
It is specifically indicated to monitor the course or response to the treatment of diseases like rheumatoid arthritis,
tuberculosis bacterial endocarditis ,acute rheumatic fever ,Hodgkins disease,temporal arthritis , and systemic lupus
erythematosis; and to diagnose and monitor giant cell arteritis and polymyalgia rheumatica.
An elevated ESR may also be associated with many other conditions, including autoimmune disease, anemia,
infection,malignancy,pregnancy, multiple myeloma, menstruation, and hypothyroidism.
Although a normal ESR cannot be taken to exclude the presence of organic disease, its rate is dependent on various
physiologic and pathologic factors.
The most important component influencing ESR is the composition of plasma. High level of C-Reactive Protein, fibrinogen,
haptoglobin, alpha-1antitrypsin, ceruloplasmin and immunoglobulins causes the elevation of Erythrocyte Sedimentation
Rate.
Drugs that may cause increase ESR levels include: dextran, methyldopa, oral contraceptives, penicillamine, procainamide,
theophylline, and Vitamin A. Drugs that may cause decrease levels include: aspirin, cortisone, and quinine
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HAEMATOLOGY
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BIOCHEMISTRY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Comment:
•C-Reactive Protein [CRP] is an acute phase reactant ,hepatic secretion of which is stimulated in response to inflammatory
cytokines.
•CRP is a very sensitive but nonspecific marker of inflammation and infection.
•The CRP test is useful in patient with Inflammatory bowel disease, arthritis, Autoimmune diseases, Pelvic inflammatory disease
(PID), tissue injury or necrosis and infections.
•CRP levels can be elevated in the later stages of pregnancy as well as with use of birth control pills or hormone replacement
therapy i.e. estrogen. Higher levels of CRP have also been observed in the obese.
•As compared to ESR, CRP shows an earlier rise in inflammatory disorders which begins in 4-6 hrs, he intensity of the rise being
higher than ESR and the recovery being earlier than ESR. Unlike ESR, CRP levels are not influenced by hematologic conditions
like Anemia, Polycythemia.
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BIOCHEMISTRY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Glucose - Fasting
Glucose - Fasting 72 mg/dL 70-100 Hexokinase/G-6-PDH
Comment:
Impaired glucose tolerance (IGT) fasting, means a person has an increased risk of developing type 2 diabetes but does not
have it yet. A level of 126 mg/dL or above, confirmed by repeating the test on another day, means a person has diabetes.
IGT (2 hrs Post meal ), means a person has an increased risk of developing type 2 diabetes but does not have it yet. A 2-hour
glucose level of 200 mg/dL or above, confirmed by repeating the test on another day, means a person has diabetes
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BIOCHEMISTRY
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Test Name Result Unit Bio. Ref. Interval Method
Lipase
Lipase 40.0 U/L 12–53 Colorimetric rate
Comment:
Pancreas is the major and primary source of serum lipase, though lipase is also secreted by the gastric and intestinal mucosa.
Lipase measurement in serum is used to diagnose acute pancreatitis.
After an attack of acute pancreatitis, serum Lipase activity increases within 4 to 8 hours,peaks at about 24 hours, and decreases
over 8 to 14 days. Concentrations often remain elevated longer than those of Amylase.The increase in serum Lipase activity is
not necessarily proportional to the severity of the attack.
Lipid Profile
Cholesterol - Total 144 mg/dL Low (desirable): < 200 Enzymatic
mg/dL
Moderate (borderline)
200–239 mg/dL
High: >/= 240 mg/dL
Triglycerides 50 mg/dL Normal: <150, GPO, Trinder without
Borderline: 150 - 199, serum blank
High:200-499,
Very High>=500
Cholesterol - HDL 61 mg/dL Undesirable/high risk Elimination/catalase
<=40mg/dL
Desirable/low
risk>=60mg/dl
Cholesterol - LDL 73 mg/dL Desirable: <100 Calculated
Above desirable: 100 -
129
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BIOCHEMISTRY
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Test Name Result Unit Bio. Ref. Interval Method
Borderline high : 130 -
159
High : 160 - 189
Very high : >=190
Cholesterol- VLDL 10 mg/dL <30 Calculated
Cholesterol : HDL Cholesterol 2.4 Ratio Desirable : 3.0-4.0 Calculated
High risk : >4
LDL : HDL Cholesterol 1.20 Ratio Desirable : 2.0-2.5 Calculated
High risk : >3.0
Non HDL Cholesterol 83 mg/dl Desirable:< 130, Calculated
Above Desirable:130 -
159,
Borderline High:160 -
189,
High:190 - 219,
Very High: >= 220
Comment:
•Lipid profile measurements in the same patient can show physiological & analytical variations. It is recommended that 3 serial
samples 1 week apart may be tested.
•Indians are at a high risk of developing atherosclerotic cardiovascular disease (ASCVD); at a much earlier age and more severe
with high mortality. Dyslipidemia (abnormal lipid profile) is the major risk factor and found in almost 80% Indians.
•Total cholesterol is the total amount of cholesterol in blood comprising of HDL, LDL-C, and VLDL.
•LDL Cholesterol (LDL-C) or “bad”cholesterol contributes most significantly to atherosclerosis leading to heart disease or
stroke and is the primary target for reducing risk for cardiovascular disease.
•High-density lipoprotein (HDL) or “good” cholesterol can lower risk of heart disease and stroke.
•Triglyceride (TG) level also plays a major role in CVD. Indians are more prone to Atherogenic dyslipidemia, a condition
associated with high TG, low HDL-C and high LDL-C; this is associated with diabetes, metabolic syndrome and insulin resistance.
Hence high triglyceride levels also need to be treated.
•Non-HDL-Cholesterol (Non-HDLC) measures all plaque forming lipoproteins (e.g. remnants, LDL-C, VLDL, Lp(a), Apo-B).
Monitoring of Non-HDLC is important in patients with high TG (e.g. diabetics, obese persons) and those already on statin
therapy.
•Lipid Association of India (LAI-2020) recommends:-
Screening of all Indians above the age of 20 years for CVD risk factors, esp. lipid profile.
Identification of Risk factors: Age (male ≥45 years, female ≥55 years); Family h/o heart disease at younger age (<55 yrs
in males, <65 yrs in female), Smoking/tobacco use, High blood pressure, Low HDL (males <40 mg/dl and females
<50mg/dl).
Fasting lipid profile is not mandatory for screening. Both fasting and non-fasting lipid profiles are equally important for
managing Indian patients.
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BIOCHEMISTRY
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Test Name Result Unit Bio. Ref. Interval Method
Non-HDLC should be calculated in every subject. LAI recommends LDL-C as the primary target and Non-HDLC as the co-
primary target for initiating drug therapy.
Lifestyle modifications are of first and foremost importance for management and prevention of dyslipidemia. Among low
risk groups, treatment is started only after 3 months of lifestyle changes.
Testing for Apolipoprotein B, hsCRP, Lp(a ) should be considered for patients in moderate risk group.
Newer treatment goals based on Risk Groups and values of LDL-C and Non-HDLC
•As per NCEP Expert Panel (2011) guidelines, universal screening for dyslipidemia is recommended for children between 9
- 11 yrs (repeat at 17-21 yrs). Screening is not recommended before the age of 2yrs. Above the age of 2 yrs, selective screening
is done in children with family history of premature CVD or risk factors like obesity, diabetes, and hypertension.
Note: Reference Interval as per National Cholesterol Education Program (NCEP) Report.
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BIOCHEMISTRY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Alkaline Phosphatase 60 U/L 46-116 IFCC Standardization
Gamma Glutamyltransferase (GGT) 14 U/L <38 Modified IFCC
Comment:
•LFTS are based upon measurements of substances released from damaged hepatic cells into the blood that gives idea of the
Existence, Extent and Type of Liver damage. - Acute Hepatocellular damage: ALT & AST levels are sensitive index of
hepatocellular damage - Obstruction to the biliary tract,Cholestasis and blockage of bile flow:1) Serum Total Bilirubin
concentration 2) Serum Alkaline Phosphatase (ALP) activity 3) Gamma Glutamyl Transpeptidase (GGTP) 4) 5`-Nucleotidase -
Chronic liver disease: Serum Albumin concentration
•Bilirubin results from the enzymatic breakdown of heme. Jaundice is a yellowish discoloration of the skin and mucous
membranes caused by hyperbilirubinemia.
•Pre-hepatic or hemolytic jaundice - Abnormal red cells, antibodies,drugs and toxins,Hemoglobinopathies, Gilbert’s syndrome,
Crigler-Najjar syndrome
•Hepatic or Hepatocellular jaundice-Viral hepatitis,toxic hepatitis, intrahepatic cholestasis
•Post-hepatic jaundice -Extrahepatic cholestasis, gallstones, tumors of the bile duct, carcinoma of pancreas
•In viral hepatitis and other forms of liver disease associated with acute hepatic necrosis, serum AST and ALT concentrations are
elevated even before the clinical signs and symptoms of disease appear.
•ALT is the more liver-specific enzyme and elevations of ALT activity persist longer than AST activity.
•Peak values of aminotransferase activity occur between the seventh and twelfth days. Activities then gradually decrease,
reaching normal activities by the third to fifth week. Peak activities bear no relationship to prognosis and may fall with worsening
of the patient's condition.
•Aminotransferase activities observed in cirrhosis vary with the status of the cirrhotic process and range from the upper
reference limit to four to five times higher, with an AST/ALT ratio greater than 1. The ratio's elevation can reflect the grade of
fibrosis in these patients. Slight or moderate elevations of both AST and ALT activities have been observed after administration
of various medications and chronic hepatic injury such as (1) hemochromatosis, (2) Wilson disease, (3) autoimmune hepatitis, (4)
primary biliary cirrhosis, (5) sclerosing cholangitis, and (6) a1-antitrypsin deficiency.
•AST activity also is increased in acute myocardial infarction, progressive muscular dystrophy and dermatomyositis, reaching
concentrations up to eight times the upper reference limit.Slight to moderate AST elevations are noted in hemolytic disease.
•GGT is a sensitive indicator of the presence of hepatobiliary disease, being elevated in most subjects with liver disease
regardless of cause. Increased concentrations of the enzyme are also found in serum of subjects receiving anticonvulsant drugs,
such as phenytoin and phenobarbital.
Amylase
Amylase 96 U/L 30.0 - 118.0 Ethylidene Blocked-
pNPG7
Comment:
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BIOCHEMISTRY
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Test Name Result Unit Bio. Ref. Interval Method
cholangiopancreatography(ERCP) and acute alcohol poisoning.
Low Amylase levels are seen in Chronic Pancreatitis,Congestive Heart failure, 2nd & 3rd trimester of pregnancy, Gastrointestinal
cancer & bone fractures.
Drugs causing increased amylase levels are aspirin,diuretics,oral contraceptives,corticosteroids,indomethacin,ethyl alcohol and opiate
intake.
In acute pancreatitis, elevated amylase levels usually parallel lipase concentrations, although lipase levels may take a bit longer to
rise,will remain elevated longer and are more specific than amylase as a marker for pancreatitis.
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Immunology
Test Name Result Unit Bio. Ref. Interval Method
Comment:
*Note -No standard reference range has yet been established for Insulin-PP in the Indian population, therefore the same could
not be provided along with the test. However, various studies done on different populations mention that the range of Insulin-
PP can vary somewhere from 5-79 mU/L which can be used for clinical purposes.
Insulin is peptide hormone secreted from Beta cells of pancreas and the secretion is regulated by primarily by the blood glucose
levels.
The levels should be measured with the concomitant blood glucose.
Insulin levels are most frequently ordered following an abnormal glucose test and/or when a patient has acute or chronic
symptoms of hypoglycemia, such as sweating, palpitations, hunger, confusion, blurred vision, dizziness, fainting, and seizures
(although these can be caused by other conditions along with low blood glucose)
Note:
A single random blood sample for insulin may provide insufficient information due to wide variation in the time responses
of insulin levels and blood glucose.
Stimulation of insulin secretion may be caused by many factors like hyperglycemia, glucagon, amino acids, growth hormone
and catecholamines
Interference in insulin assay is seen due to insulin antibodies which develop in patients treated with bovine or porcine
insulin.
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Immunology
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Vitamin D (25-OH)
Vitamin D (25-OH) 19.0 ng/ml Deficiency:< 20, CLIA
Insufficiency:20-29,
Sufficiency:30 - 100,
Toxicity possible:> 100
Comment:
Vitamin D is a fat-soluble steroid prohormone involved in the intestinal absorption of calcium and the regulation of calcium
homeostasis.
Two forms of vitamin D are biologically relevant - vitamin D3 (Cholecalciferol) and vitamin D2 (Ergocalciferol).
Both vitamins D3 and D2 can be absorbed from food but only an estimated 10-20perc. of vitamin D is supplied through
nutritional intake.
Vitamin D is converted to the active hormone 1,25-(OH)2-vitamin D (Calcitriol) through two hydroxylation reactions. The
first hydroxylation converts vitamin D into 25-OH vitamin D and occurs in the liver. The second hydroxylation converts 25-
OH vitamin D into the biologically active 1,25-(OH)2-vitamin D and occurs in the kidneys as well as in many other cells of
the body.
Most cells express the vitamin D receptor and about 3perc. of the human genome is directly or indirectly regulated by the
vitamin D endocrine system.
The major storage form of vitamin D is 25-OH vitamin D and is present in the blood at up to 1,000 fold higher
concentration compared to the active 1,25-(OH)2-vitamin D. 25-OH vitamin D has a half-life of 2-3 weeks vs. 4 hours for
1,25-(OH)2-vitamin D. Therefore, 25-OH vitamin D is the analyte of choice for determination of the vitamin D status.
Risk factors for vitamin D deficiency include low sun exposure, inadequate intake, decreased absorption, abnormal
metabolism, vitamin D resistance and and liver or kidney diseases.
Vitamin D deficiency is a cause of secondary hyperparathyroidism and diseases resulting in impaired bone metabolism (like
rickets, osteomalacia).
Recently, many chronic diseases such as cancer, high blood pressure, osteoporosis and several autoimmune diseases
have been linked to vitamin D deficiency.
The assay measures both D2 (Ergocalciferol) and D3 (Cholecalciferol) metabolites of vitamin D
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SEROLOGY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Comment:
Infection with HBV results in a wide spectrum of acute and chronic liver diseases that may lead to cirrhosis and hepatocellular
carcinoma. Hepatitis B surface antigen (HBsAg), derived from the viral envelope, is the first antigen to appear following infection
and is detectable in the serum.
Note:
•This is a Rapid, Screening Test for Qualitative detection of HBsAg.
•All Provisionally Reactive cases must be confirmed by confirmatory method to rule out false positives due to interfering
substances.
Limitations:
•For diagnostic purposes, results should be used in conjunction with patient history and other hepatitis markers for diagnosis of
acute and chronic infection.
•Additional follow up testing using other available methods is required ,if this test is Non- Reactive in the presence of persisting
clinical symptoms of Hepatitis B.
•In few cases,false positive results can be obtained due to presence of other antigens or elevated levels of Rheumatoid factor.
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CLINICAL PATHOLOGY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Comment:
•Note: Pre-test condition to be observed while submitting the sample-first void, mid stream urine, collected in a clean, dry, sterile
container is recommended for routine urine analysis, avoid contamination with any discharge from vaginal, urethra, perineum,
Avoid prolonged transit time & undue exposure to sunlight.
•During interpretation, points to be considered are Negative nitrite test does not exclude the urinary tract infections. Trace
proteinuria can be seen with many physiological conditions like prolonged recumbency, exercise, high protein diet. False positive
reactions for bile pigments, proteins, glucose and nitrites can be caused by peroxidase like activity by disinfectants, therapeutic
dyes, ascorbic acid and certain drugs.• Urine microscopy is done in centrifuged urine specimens
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CLINICAL PATHOLOGY
COMPREHENSIVE PLATINUM FULL BODY CHECKUP WITH SMART REPORT
Test Name Result Unit Bio. Ref. Interval Method
Test results released pertain to the sample, as received. Laboratory investigations are only a tool to facilitate in arriving at a diagnosis and should
be clinically correlated by the interpreting clinician. Result delays may happen because of unforeseen or uncontrollable circumstances. Test report
may vary depending on the assay method used. Test results may show inter-laboratory variations. Test results are not valid for medico-legal
purposes. Please mail your queries related to test results to Customer Care mall ID [email protected]
Disclaimer: Results relate only to the sample received. Test results marked "BOLD" indicate abnormal results i.e. higher or lower than normal. All
lab test results are subject to clinical interpretation by a qualified medical professional. This report cannot be used for any medico-legal purposes.
Partial reproduction of the test results is not permitted. Also, TATA 1mg Labs is not responsible for any misinterpretation or misuse of the
information. The test reports alone may not be conclusive of the disease/condition, hence clinical correlation is necessary. Reports should be
vetted by a qualified doctor only.
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