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Abstract of Paper Presentraion (Updated)

paper presntation

Uploaded by

shabnam khan
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© © All Rights Reserved
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“A Cross Sectional Study to Assess the Effects of Tobacco Consumption on

Pulmonary Function Tests”


Shabnam1, Vyas S2, Bhimwal R3
1
Ph.D. Scholler, 2Sr. Professor, 3Sr. Professor
1,2
Department of Physiology, Sawai Man Singh Medical College, Jaipur (Rajasthan)
3
Department of General Medicine, Sawai Man Singh Medical College, Jaipur (Rajasthan)
1
Correspondence Email: [email protected]

ABSTRACT
Background: Tobacco use poses a significant global and Indian public health challenge,
being the leading cause of preventable deaths. It's consumed in various forms like smoking,
chewing, and snuffing. In India, bidi (54%), cigarettes (9%), and smokeless tobacco (27%)
are prevalent. Harmful substances in tobacco smoke can cause oxidative lung damage,
including neutrophil accumulation, while smokeless tobacco damages the buccal mucous
membrane, potentially leading to mitotic changes. The slow development of nicotine
dependency is a key concern in tobacco-related diseases. Hence, this study aims to assess the
impact of different tobacco forms on pulmonary functions.
Objectives: To compare the Pulmonary function tests in Cigarette smokers, Bidi smokers ,
Tobacco chewers and control group.
Method: A cross-sectional study was carried out in the Department of Physiology,SMS
Medical College, Rajasthan. A total 280 males of the 20 to 40 years age group who had given
their consent, were recruited into 4 study groups namely, controls, tobacco chewers, cigarette
smokers, and bidi smokers having 70 individuals in each group. Spirometric parameters
studied were FVC (forced vital capacity), FEV1 (forced expiratory volume in one second),
FEV1/FVC ratio, PEFR (peak expiratory flow rate), FEF 25-75 (Flow expiratory flow rate (25-
75%))
Result: In the present study reviewed that FVC, FEV1, FEF, and PEFR were significantly
lower in cigarette smokers, bidi smokers, and tobacco chewers than control group.
(P<0.001).FEV1/FVC ratio was significantly lower in cigarette and bidi smokers than the
control group (P<0.05) but the change was not significant in tobacco chewers.
Conclusion: Nicotine dependence exacerbates respiratory function in tobacco users. Tobacco
smoke contains harmful substances like tar, nitric oxide, carbon monoxide, and carcinogens
like benzopyrene, leading to diseases such as COPD and bronchogenic carcinoma. Smokeless
tobacco increases free radical production, and reduces antioxidant levels resulting in a
decrease in pulmonary function tests

Key Words: Tobacco, smoking, smokeless tobacco, pulmonary function tests.

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