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1.5 PHARMACEUTICAL INORGANIC CHEMISTRY (THEORY)

Theory : 2 Hrs. /Week

1. Scope and objectives: This course mainly deals with fundamentals of Analytical
chemistry and also the study of inorganic pharmaceuticals regarding their monographs
and also the course deals with basic knowledge of analysis of various
pharmaceuticals.

2. Upon completion of the course student shall be able to:


a. under stand the principles and procedures of analysis of drugs and also regarding
the application of inorganic pharmaceuticals;
b. know the analysis of the inorganic pharmaceuticals their applications; and
c. appreciate the importance of inorganic pharmaceuticals in preventing and curing
the disease.

3. Course materials:
Text books
a. A text book Inorganic medicinal chemistry by Surendra N. Pandeya
b. A. H. Beckett and J. B. Stanlake’s Practical Pharmaceutical chemistry Vol-I &
Vol-II
c. Inorganic Pharmaceutical Chemistry III-Edition P.Gundu Rao
Reference books
a. Inorganic Pharmaceutical Chemistry by Anand & Chetwal
b. Pharmaceutical Inorganic chemistry by Dr.B.G.Nagavi
c. Analytical chemistry principles by John H. Kennedy
d. I.P.1985 and 1996, Govt. of India, Ministry of health

4. Lecture wise programme:


Topics
1 Errors
2 Volumetric analysis
3 Acid-base titrations
4 Redox titrations
5 Non aqueous titrations
6 Precipitation titrations
7 Complexometric titrations
8 Theory of indicators
9 Gravimetry
10 Limit tests
11 Medicinal gases
12 Acidifiers
13 Antacids
14 Cathartics
15 Electrolyte replenishers
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16 Essential Trace elements


17 Antimicrobials
18 Pharmaceutical aids
19 Dental Products
20 Miscellaneous compounds
21 Radio Pharmaceuticals

1.5 PHARMACEUTICAL INORGANIC CHEMISTRY (PRACTICAL)

Practical : 3 Hrs./Week

1. Limit test (6 exercises)


a. Limit test for chlorides
b. Limit test for sulphates
c. Limit test for iron
d. Limit test for heavy metals
e. Limit test for arsenic
f. Modified limit tests for chlorides and sulphates

2. Assays (10 exercises)


a. Ammonium chloride- Acid-base titration
b. Ferrous sulphate- Cerimetry
c. Copper sulpahte- Iodometry
d. Calcilugluconate- Complexometry
e. Hydrogen peroxide – Permanganometry
f. Sodium benzoate – Nonaqueous titration
g. Sodium chloride – Modified volhard’s method
h. Assay of KI – KIO3 titration
i. Gravimetric estimation of barium as barium sulphate
j. Sodium antimony gluconate or antimony potassium tartarate

3. Estimation of mixture (Any two exercises)


a. Sodium hydroxide and sodium carbonate
b. Boric acid and Borax
c. Oxalic acid and sodium oxalate

4. Test for identity (Any three exercises)


a. Sodium bicorbonate
b. Barium sulphate
c. Ferrous sulphate
d. Potassium chloride
30

5. Test for purity (Any two exercises)


a. Swelling power in Bentonite
b. Acid neutralising capacity in aluminium hydroxide gel
c. Ammonium salts in potash alum
d. Adsorption power heavy Kaolin
e. Presence of Iodates in KI

6. Preparations (Any two exercises)


a. Boric acids
b. Potash alum
c. Calcium lactate
d. Magnesium suphate

Scheme of Practical Examination :


Sessionals Annual
Synopsis 05 15
Major Experiment 10 25
Minor Experiment1&2 03 15
Viva 02 15
Max Marks 20 70
Duration 03hrs 04hrs
Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity,
promptness, viva-voce and record maintenance).

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