11 Neural Control and Chemical Coordination
11 Neural Control and Chemical Coordination
01) The homeostatic regulation of an animal requires three basic components …. To detect
changes, ……. To evaluate the changes and ……. To adjust the changes respectively. Fill in the
blanks with correct option.
(a) receptor, affectors, effectors (b) brain, spinal cord, effectors
(c) receptors, integrators, effectors (d) receptors, integrators, effectors
09) The nerve centres, which controls the body temperature and the urge for eating are contained
in
(a) hypothalamus (b) pons (c) cerebellum (d) thalamus
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10) Cerebro spinal fluid (CSF) is found within the
(a) epidural space, subarachnoid space and dural sinuses
(b) the subarachnoid space, dural sinuses and ventricles
(c) central canal, epidural space and subarachnoid space
(d) ventricles, central canal and subarachnoid space
13) Which of the following are the three initial developmental regions of the brain?
(a) Telencephalon, prosencephalon, rhombencephalon
(b) Rhombencephalon, prosencephalon, mesencephalon
(c) Metencephalon, myelecephalon, prosencephalon
(d) Prosencephalon, diencephalon, mesencephalon
23) Which one of the following is an example of negative feedback loop in humans?
(a) Constriction of skin, blood vessels and contraction of skeletal muscles, when it is too cold
(b) Secretion of tears after falling of sand particles into the eye
(c) Salivation of mouth at the sight of delicious food
(d) Secretion of sweat glands and construction of skin blood vessels, when it is too hot
28) Potential difference across resting membrane is negatively charged. This is due to differential
distribution of the following ions.
(a) Na+ and K+ ions (b) and ions
2+ 2+ +4 -
(c) Ca and Mg ions (d) Ca and Cl ions
29) An action potential in the nerve fibre is produced when positive and negative charges on the
outside and the inside of the axon membrane are reversed because
(a) more potassium ions ether the axon as compared to sodium ions leaving it
(b) more sodium ions enter the axon as compared to potassium ions leaving it
(c) All potassium ions leave the axon
(d) all sodium ions enter the axon
30) Na+ - K+ pump is found in membranes of many cells like nerve cells. It works against electro
chemical gradient and involves an integral protein ATPase. For each molecule of ATP used.
(a) 3 ions of Na+ are pumped out and 2 ions of k+ are taken in
(b) 3 ions of Na+ Y89 are takne in and 2 ions of k+ are pumped out
(c) 2 ions of Na+ are thrown out and 3 ions of k+ are absorbed
(d) 3 ions of k+ are absorbed and 3 ions of Na+ are pumped out
31) Unidirectional transmission of a nerve impulse through nerve fibre is due to the fact that
(a) nerve fibre is insulated by a medullary
(b) sodium pump starts operating only at the cyton and then continues into the nerve fibre
(c) neurotransmitters are released by dendrites and not by axon endings
(d) neurotransmitters are released by the axon ending and not by dendrites
33) In the resting state of the neural membrane, diffusion due to concentration gradients, if
allowed, would drive
(a) K+ into the cell (b) K+ and ka+ out of the cell
(c) Na+ into the cell (d) Na+ out of the cell
34) During the transmission of nerve impulse through a nerve fibre, the potential on the ineer side of
the plasma membrane has which type of electric charge>
(a) First negative, then positive and again back to negative
(b) First positive, then negative and continue to be negative
(c) First negative, then positive and continue to be positive
(d) First positive, then negative and again back to positive
35) Parkinson’s disease (characterized by tremors and progressive rigidity of limbs) is caused by
degeneration of brain neurons that are involved in movement control and make use of
neurotransmitter
(a) acetylcholine (b) norepinephrine (c) dopamine (d) GABA
37) Chemicals which are released at the synaptic junction are called
(a) hormones (b) neutotransmitters (c) cerebrospinal fluid (d) lymph
38) Identify the parts labelled as A to E and choose the correct option for the given diagrammatic
representation of reflex action showing knee-jerk reflex.
44) The point in eye of mammals from which optic nerves and blood vessels leave the eye ball is
(a) yellow spot (b) blind spot (c) pars optica (d) None of the above
47) In the blind spot, where the optic nerves leave the eyes
(a) rods and cones are absent (b) only cones are present
(c) only rods are present (d) special neurons are present
49) Examine the diagram of the two cell types A and B given adjacent and select the correct option
(a) cell A is the rod cell found evenly all over retina
(b) cell A is the cone cell more concentrated in the fovea centralis
(c) cell B is concerned with colour vision in bright light
(d) cell A is sensitive to low light intensities
50) The defective condition of eye, in which distant objects are seen distinct but near
objects are indistinct is called
(a) myopia (b) astigmatism
(c) presbyopia (d) hypermetropia
(b) eye ball is normal but image is formed over blind spot
(c) eye ball is normal but image is formed slightly behind the retina due to faulty lens
(d) curvature of cornea becomes irregular
58) Below is the diagram of the sectional view of cochlea of human ear,
identify A to E choose the correct option
(a) A – Scala media, B – Organ of corti, C – Basilliar membrane,
D – Scala tympani, E – Scala vestibuli
(b) A – Scala vestibuli, B – Organ of corti, C – Basilliar membrane,
D – Scala tympani, E – Scala media
(c) A – Scala vestibuli, B –Basilliar membrane C – Organ of corti,
D – Scala tympani, E – Scala media
(d) A – Scala vestibuli, B –Basilliar membrane C – Scala tympani,
D – Organ of corti, E – Scala media
61) Which one of the following pairs correctly matches a hormone with a disease resulting from its
deficiency?
63) The hormone, which brings about the contraction of gall bladder is
(a) oxytocin (b) gastrin (c) cholecystokinin (d) secretin
66) While dwarfs and cretins are somewhat of the same height, the main difference is that
(a) dwarfs have normal intelligence, while cretins do not
(b) cretins are mentally deranged
(c) the head of cretin is especially large
(d) the dwarfs have elongated chin
67) Hormone that promotes cell division, protein synthesis and bone growth is
(a) ADH (b) ACTH (c) PTH (d) GH
68) If a person takes large amount of water, the amount of ADH in blood will
(a) increase (b) decrease
(c) first increase then decrease (d) will remain unchanged
70) Stimulation of the mother’s nipples by a nursing baby initiates a sensory impulses, which pass
into the central nervous system and eventually reach the hypothalamus. These impulses result
in
(a) synthesis and release of prolactin from the posterior
(b) release of lactogenic hormone from the anterior pituitary
(c) release of oxytocin from the posterior pituitary
(d) release of prolactin inhibiting factor
79) A person passes excessive urine and drinks much water but his glucose level
is normal. It is due to
(a) increased secretion of glucagon
(b) fall in glucose released in urine
(c) reduction in insulin secretion
(d) reduction in vasopressin secretion in posterior pituitary
81) The portion of the pituitary gland that arises from the roof of the primitive oral cavity is the
(a) adenohypophysis (b) pars nervosa
(c) neurohypophysis (d) infundibulum
85) Hormones thyroxin, adrenalin and pigment melanin are the formed from
(a) glycine (b) tryptophan (c) tyrosine (d) proline
86) Which endocrine gland stores its secretion in extracellular spaces before discharging into
blood?
(a) testes (b) pancreas (c) thyroid (d) Adrenal
87) Thyrocalcitonin
(a) elevates k+ level in blood (b) lowers Ca2+ level in blood
(c) elevates Ca2+ level in blood (d) None of the above
92) A person is having problems with calcium and phosphorus metabolism in his body. Which one
of the following glnds may not be functioning properly?
(a) parathyroid (b) parotid (c) pancreas (d) Thyroid
99) Which one of the following is correctly matched pair of the given secretion and its primary role
in human physiology?
(a) sebum - sexual attraction (b) Sweat - thermoregulation
(c) Saliva - Tasting food (d) tears - excretion of salts
103) Renin is
(a) an enzyme present in the gastric juice of mammals
(b) a substance excreted through the kidney
(c) a protein produced by some cells present in the cortex of kidney
(d) None of the above
105) Which hormone causes dilation of blood vessels, increased oxygen consumption and
glycogenolysis?
(a) ACTH (b) insulin (c) Adrenaline (d) Glucagon
107) The endocrine gland that is formed from two different germ layers is the
(a) ovary (b) thyroid gland
(c) pancreas (d) adrenal gland
108) The group of adrenocortical hormones concerned with electrolyte balance is the
(a) glucocorticoids (b) mineralocorticoids
(c) androgens (d) epinephrine and norepinephrine
111) What is the proper sequence of adrenal cortex zones, from the outside in?
(a) zona glomerulosa, zona fasciculata, zona reticularis
(b) zona glomerulosa, zona reticularis, zona fasciculata
(c) zona reticularis, zona fasciculate, zona glomerulosa
(d) zona fasciculate, zona reticularis, zona glomerulosa
113) Feeling the tremors of an earthquake a scared resident of seventh floor of a multistoried
building starts climbing down the stairs rapidly. Which hormone initiated this action.
(a) thyroxin (b) Adrenaline (c) Glucagone (d) pineal
115) Which one of the following glands is correctly matched with the accompanying description?
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(a) Thyroid - Hyperactivity in young children causes cretinism
(b) Thymus - Starts undergoing atrophy after puberty
(c) Parathyroid - Secretes parathormone, which promotes movement of calcium ions
from blood into bones during calcification
(d) Pancreas - Delta cells of the islets of langerhans secrete a hormone, which
stimulates glycolysis in liver
116) The hormone that controls the level of calcium and phosphorus in the blood is secreted from
(a) thyroid (b) parathyroid (c) pituitary (d) thymus
117) Both the ovaries are removed from a female rat. The hormone titre decreases in case of
(a) oxytocin (b) prolactin
(c) oestrogen (d) gonadotropin releasing factor
122) Withdrawal of which of the following hormones is the immediate cuase of menstruation
(a) Oestrogens (b) FSH (c) FSH - RH (d) Progesterone
124) Through negative feedback, a hormone may shut of the secretion of an anterior pituitary
hormone by
(a) stimulating the release of a ( hypothalamic) releasing hormone
(b) inhibiting the release of a (hypothalamic) inhibiting
(c) inhibiting the release of a (hypothalamic) releasing hormone
(d) All of the preceding
125) Which one of the following is not a second messenger in hormone action?
(a) c-GMP (b) Calcium (c) sodium (d) c-AMP
126) In hormone action, if receptor molecules are removed from target organ the target organ will
(a) continue to respond to hormone
(b) not respond to hormone
(c) continue to respond but requires higher concentration
(d) continue to respond but in the opposite any
128) In a man, abducens nerve is injured. Which one of the following functions will be affected?
(a) movement of the eye ball (b) swallowing
(c) movement of the tongue (d) movement of the neck
129) Which of the following hormones is not a secretion product of human placenta?
(a) Human chorionic gonadotropin (b) Prolactin
(c) Oestrogen (d) Progesterone
134) In fishes, the lateral line receptors are neuromast organs. These are
(a) olfactoreceptor (b) gustatoreceptors
(c) rheoreceptors (d) chemoreceptors
Direction: (Q. Nos. 141 - 146) In each of the following questions a statement of Assertion is given
followed by a corresponding statement of Reason just below it. Of the statements, mark the
correct answer as
(a) If both Assertion and Reason are true and Reason is the correct explanation of Assertion
(b) If both Assertin and Reason are true, but Reason is not the correct explanation of Assertion
(c) If Assertion is true, but Reason is false
(d) If both Assertion and reason are false
141) Assertion: The name master endocrine gland of body is given to the pituitary gland.
Reason: Hypothalamus controls over the master gland.
142) Assertion: The imbalance in concentration of Na+, k+ and proteins generates resting potential
Reason: To maintain the unequal distribution of Na+ and k+, the neurons use electrical energy
143) Assertion: Hypoglycemia disorder is due to imbalance of glucagon and insulin hormone.
Reason: In hypoglycemia, the level of insulin is decreased and glucagon is increased
145) Assertion: Diabetes insipidus is marked by excessive urination and too much thirst of water
Reason: Anti-Diuretic Hormone (ADH) is secreted by the posterior lobe of pituitary gland.
149) Column I lists some disorders associated with brain and column II lists the causes for these
disorders. Match these two columns and identify the correct option from those given
Column I Column II
A Epilepsy 1. Degeneration of neurons on the cerebral cortex
B Alzheimer’s disease 2. Irregular electrical discharge in the neurons
C Parkinson’s disease 3. Decreased production of acetylcholine
D Huntington’s chorea 4. Degeneration of dopaminegric neurons
5. Formation of blood clots in the brain
Code:
A B C D
(a) 5 4 3 1
(b) 2 3 1 4
(c) 2 3 4 1
(d) 2 3 3 1
154) Which one of the following hormones through synthesized elsewhere, is stored and released by
the master gland?
(a) Antidiuretic hormone (b) Luteinizing hormone
(c) prolactin (d) Melanocyte stimulating hormone
155) Which one of the following hormones is not involved in sugar metabolism?
(a) Cortisone (b) Aldosterone (c) insulin (d) Glucagon
156) Destructin of the anterior horn cells of the spinal cord would result in loss of
(a) sensory impulses (b) voluntary motor impulses
(c) commissural impulses (d) integrating impulses
157) A chemical signal that has both endocrine and neural roles is
(a) melatonin (b) calcitonin (c) epinephrine (d) cortisol
158) Which of the following regions of the brain is incorrectly paired with its function
(a) Medulla oblongata – Homeostatic control
(b) Cerebellum – Language comprehension
(c) Corpus callosum – Communication between the left and right cerebral cortices
(d) Cerebrum – calculation and contemplation
162) Identify the hormone with its correct matching of source and function.
(a) Oxytocin - posterior pituitary growth and maintenance of mammary glands
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(b) Melatonin - Pineal gland, regulates the normal rhythm of sleep-wake cycle
(c) Progesterone - Corpus luterm, stimulation of growth and activities of female
secondary sex organs
(d) Atrial natriuretic - ventricular wall increases blood pressure.
factor
164) A diagram showing axon terminal and synapse is given identify correctly at least two of A-D
165) Which of the following statements is correct in relation to the endocrine system?
(a) Organs in the body like gastrointestinal tract, heart, kidney and liver do not produce any hormones
(b) Non – Nutrient chemicals produced by the body in trace amount that act as intercellular
messenger are known as hormones.
(c) Releasing and inhibitory homones are produced by the pituitary gland
(d) Adenophyphysis is under direct neural regulation of the hypothalamus
166) A pregnant female delivers a baby who suffers from stunted growth, mental retardation low
intelligence quotient and abnormal skin. This is the result of
(a) low secretion of growth hormone (b) cancer of the thyroid gland
(c) over secretion of pars distalis (d) deficiency of iodine in diet
171) A person entering an empty room suddenly finds a snake right in front, on opening the door.
Which one of the following is likely to happen in his neurohormonal control system?
(a) Sympathetic nervous system is activated releasing epinephrine and norepinephrine from adrenal medulla
(b) Neurotransmitters diffuse rapidly across the cleft and transmit a nerve impulse
(c) Hypothalamus activates the parasympathetic division of brain
(d) Sympathetic nervous system is activated the parasympathetic division of brain
172) The Leyding cells as found in the human body are the secretory source of
(a) progesterone (b) intestinal mucus (c) glucagon (d) androgens
173) Which one of the following pairs of hormones are the examples of those that can easily pass
through the cell membrane of the target cell and bind to a receptor inside it (mostly in the
nucleus)?
(a) Insulin and glucagon (b) Thyroxine and insulin
(c) Somatostain and oxytocin (d) cortisol and testosterone
176) Which part of the human ear plays no role in hearing as such, but is otherwise very much
required?
(a) Eustachian tube (b) Organ of corti (c) vestibular apparatus (d) Ear ossicles
177) The purplish – red pigment rhodopsin contained in the rods type of photoreceptor cells of the
human eyes is a derivative of
(a) vitamin - C (b) vitamin - D (c) vitamin – A (d) vitamin – B
178) When a neuron is in resting state, i.e not conducting any impulse, the axonal membrane is
(a) equally permeable to both Na+ and k+ ions (b) impermeable to both Na+ and K+ ion
(c) comparatively more permeable to K ions and nearly impermeable to Na+ ions
+
(d) comparatively more permeable to Na+ ions and nearly impermeable to k+ ions
179) Match the source gland with its respective hormone as well as the function.
181) Injury to adrenal cortex is not likely to affect the secretion of which one of the following?
(a) Aldosterone
(b) Both androstenedione and dehydropiandrosterone
(c) Adrenaline (d) Cortisol
183) Toxic agents, present in food which interfere with thyroxine synthesis, lead to the development
of
(a) toxic goiter (b) cretinism (c) simple goitre (d) thyrotoxicosis
11 (d) 12 (d) 13 (a) 14 (c) 15 (d) 16 (b) 17 (a) 18 (b) 19 (b) 20 (a)
21 (b) 22 (d) 23 (a) 24 (a) 25 (d) 26 (b) 27 (c) 28 (a) 29 (c) 30 (a)
31 (d) 32 (c) 33 (c) 34 (a) 35 (c) 36 (a) 37 (b) 38 (b) 39 (b) 40 (a)
41 (d) 42 (a) 43 (b) 44 (b) 45 (d) 46 (b) 47 (a) 48 (b) 49 (b) 50 (d)
51 (a) 52 (a) 53 (d) 54 (a) 55 (b) 56 (d) 57 (d) 58 (a) 59 (b) 60 (c)
61 (a) 62 (d) 63 (c) 64 (c) 65 (c) 66 (b) 67 (d) 68 (b) 69 (c) 70 (c)
71 (a) 72 (c) 73 (b) 74 (a) 75 (a) 76 (b) 77 (c) 78 (d) 79 (d) 80 (a)
81 (a) 82 (a) 83 (b) 84 (d) 85 (c) 86 (c) 87 (b) 88 (c) 89 (b) 90 (b)
91 (b) 92 (a) 93 (c) 94 (d) 95 (a) 96 (d) 97 (a) 98 (b) 99 (b) 10 (c)
0
101 (d) 10 (b) 10 (c) 10 (b) 10 (c) 10 (c) 10 (d) 10 (d) 10 (c) 11 (a)
2 3 4 5 6 7 8 9 0
111 (a) 11 (a) 11 (b) 11 (d) 11 (b) 11 (d) 11 (c) 11 (c) 11 (c) 12 (a)
2 3 4 5 6 7 8 9 0
121 (a) 12 (d) 12 (a) 12 (c) 12 (c) 12 (b) 12 (c) 12 (a) 12 (b) 13 (d)
2 3 4 5 6 7 8 9 0
131 (b) 13 (a) 13 (b) 13 (a) 13 (c) 13 (c) 13 (b) 13 (d) 13 (d) 14 (a)
2 3 4 5 6 7 8 9 0
141 (b) 14 (c) 14 (c) 14 (a) 14 (b) 14 (c) 14 (c) 14 (a) 14 (c) 15 (c)
2 3 4 5 6 7 8 9 0
151 (d) 15 (a) 15 (b) 15 (a) 15 (b) 15 (b) 15 (c) 15 (b) 15 (a) 16 (c)
2 3 3 5 6 7 8 9 0
161 (d) 16 (b) 16 (c) 16 (d) 16 (b) 16 (d) 16 (c) 16 (c) 16 (a) 17 (c)
2 3 4 5 6 7 8 9 0
171 (a) 17 (d) 17 (d) 17 (c) 17 (d) 17 (c) 17 (c) 17 (c) 17 (a) 18 (d)
2 3 4 5 6 7 8 9 0
181 (c) 18 (a) 18 (c) 18 (a)
2 3 4