3 Experiment Urinary System
3 Experiment Urinary System
01 Introduction,
02 URINARY SYSTEM
Objectives
After following this topic, and any additional reading, you should know:
• The organization of the urinary system.
• The organization of the kidney, and the organization and functions of the nephron and conducting
tubules.
• How to recognize and identify the five major segments of the nephron: renal corpuscles, proximal
and distal convoluted tubules, loops of Henle and collecting tubules, and appreciate how the histol
ogical structure of these components is related to their functions.
• The components of the glomerulus that filter urine.
• The structure of the urinary epithelium and describe the ways in which it is adapted for its functio
n.
• Recognize and describe sections of ureter and bladder.
KIDNEY
This is stained section of kidney -showing th
e outer cortex and the inner medulla.
The medulla is full of renal tubules, but do
es not contain renal corpuscles.
All the renal corpuscles are found in the co
rtex.
• This section shows a renal cor
puscle. See if you can identify
Bowman's capsule, and the ren
al corpuscle.
• It is helpful to remember that t
his is a cross section through t
he capsule, which is in reality
an ovoid structure.
URETER
• A thick, fibroelastic, lamina propria lies underneath the epit
helium.
• This mucosa (epithelium and lamina propria) is protective.
• There are no mucosal or submucosal glands, and no submuc
osa.
• There is a layer of smooth muscle outside the mucosa:
❑ The upper two-thirds has two layers of smooth muscle: inne
r longitudinally arranged, and outer circularly arranged.
❑ The lower third has three layers of smooth muscle; Inner lo
ngitudinal, middle circular, outer longitudinal.
• Urine is squeezed into the bladder by peristalsis.
• Outer adventitial layer has fibroelastic connective tissue, wi
th blood vessels, lymphatics and nerves. The ureter (one per kidney) is a long, straight, mus
• Folds of mucosa help to protect against reflux of urine when cle-walled tube. The epithelium lining this tube is s
the bladder is full. tratified, transitional epithelium.
BLADDER
• The bladder has three layers of smooth m
uscle, and a transitional epithelium. It's h
arder to make out the three layers, becau
se the bladder is sac like, not a tube.
• The mucosa is heavily folded - this helps
to accommodate for large volume change
s.
• The transitional epithelial lining can stret
ch until it looks like stratified squamous
epithelium.
URETHRA
• The urethra conveys urine from the bladder
to the exterior of the body.
• It is similar in structure to the ureter, though
shorter.
• The lumen is kept closed, unless urine is bei
ng passed.
• The female urethra is lined by stratified col
umnar epithelium, with a few small mucosa
l glands that secrete mucus, and is bound to
the anterior wall of the vagina by an externa
l layer of fibrous connective tissue
LAB PERFORMANCE
Thanks