Presentation on

Review of flaxseed
Presented by :
Aher preeti (01)
Babar Rupesh(02)
Bhere Nikita (03)
Bhoir Tanvi (04)
Chauhan Preeti (05)
(Final Year B. Pharmacy )
Guided by :
Prof. Dr. Sonali V. Uppalwar

Ideal Institute of pharmacy, Wada, Palghar.

Outline
 Abstract
 Introduction
 Plan of work
 Literature Review
 Pharmacognosy
 Nutritional value of flaxseed
 Health benefit of flaxseed
 Pharmacological activity of flaxseed
 Result and discussion
 Conclusion
ABSTRACT :
Background : The flaxseed (Linum usitatissimum) obtained from dried ripe seeds
belonging to family-Linaceae they have been recognized as a linseed due to
abundance of omega3 fatty acids,which give energetic proteins and nutrients to hair
follicles, boost circulation in the scalp, and inhibit hair follicle tenderness that
inhibits hair fall.
Methods:-Literature has been collected through Pubmed, Goggle scholar, Web of
science ,and a Library. This review shares updated information on the botany ,health
benefits, phytochemistry and pharmacological activity of flaxseeds.
Result:-Bioactive components of flaxseeds exhibited a wide range of activities such a
anticoagulant,anticancer,antihypertensive,antihyperlipidemic,antioxidants,antiarrhyt
hmatic.This seed is gaining importance for its use in pharmaceuticals, food and
cosmetic products.
Conclusion: Existing literature Authenticates the potential benefits of flaxseeds from
nutritional as well as medicinal perspective.
INTRODUCTION :
Flaxseed is the seed from the flax plant,an annual herb,which is a member of the linaceae family .
It thrivesin deep moist soils rich in sand,silt,clay.
The specie is native to the region extending from the eastern Mediterranean,through Western Asia and the middle
East,to India.
The latin name of flaxseed(Linum usitatissimum L.)means “very useful” ,and it has two basic varieties :brown and
yellow or golden (also known as golden linseeds).
flaxseed is emerging as an important functional food ingredient because provides oil rich in omega-3, digestible
proteins, and lignans.
flaxseed is full of fatty-acids and anti-oxidants which help to remove toxins and dead cells from the scalp.
Flaxseed gel can be applied to scalp and hair as a moisturizer that can help to stimulate growth and improve the
strength of existing hair.
Flaxseed is establishing importance in the world’s food chain as
a functional food.
Functional food can be defined as the food or food ingredients that may provide
physiological benefits and helps in preventing and/or curing of diseases.
Flaxseeds contain about 55 % ALA, 28–30 % protein and 35 % fiber.
ALA is one of the essential polyunsaturated fatty acid
and reported to exhibit anti-inflammatory, anti-thrombotic and anti-arrhythmic properties.
PLAN OF WORK
AIM : To estimate a review of flaxseed.
OBJECTIVE :
1.To evaluate the chemical composition and pharmacological activity of flaxseed.
2.To identify the health benefits and nutritional value of flaxseed.
3.To understand awareness among the people knowledge about the flaxseed and their uses.
4.To understand whether people are suffering from any health problem that can be easily cure
by the flaxseed.
5.To provide and establish people’s brief knowledge about the flaxseed
SURVEY :
1.Conducting a population survey on “Flaxseed : A Review “.
2.Collecting information regarding the topic.
3.Preparation of questionnaire for google form.
4.Analyzing all responses.
5.Aggregation of similar factors for study.
6.converting data from verbal to non-verbal (pie charts).
7.Comparison study data. people’s brief knowledge about the flaxseed.
Review Methodology :

Collecting review articles from internet sources.

Collecting information

Sorting the data regarding the project.

Literature Review
1. Amin T. Thakur m . Comparative study of immediate composition, screening of phytochemicals,
antioxidants and antimicrobial properties of Linum usitatissimum L. (flax). App Int J Curr
Microbial Sci. 2014; 3 (4): 465-481. Linum usitatissimum L. (linsemo) has a multifaceted function.
Interdisciplinary Research Journal. 2014; 4 (1): 220-235.et al (2014)

Flaxseed (LINUM USITATISSIUM) is belonging to family LINEACEA. This review summarizes the
information about the phytochemistry, pharmacological activity and toxicity of Flaxseeds. Flaxseeds have
many benefits such as healthy skin, hair growth, weight loss, lower cholesterol, act as a antioxidants ,etc.

2.Mr. Shaikh Akbar , Mr. Mirza Nazish Baig , Miss. Desahmane Amruta,Assistant Professor,
G.M.C College of Pharmacy, Aurangabad (M.S.) ,Lecturer, R.B.T College of D. Pharmacy,
Aurangabad (M.S.), et al (August 2021).

Flaxseeds are also called as Alsi, Jawas, Aksebija in Indian languages The lignan content in flaxseed is
significantly higher than any other plants. This herbs is known as one of the best dietary sources of
Omega-3 fatty acids and lignan.The review focuses on health benefit of flaxseed and food applications to
make people aware about it.
3. Bernacchia R, Preti R, and Vinci G. Chemical Composition and Health Benefits of Flax. Austin J.
Food Nutri Sci. 2014;2(8):1045. ISSN: 2381-8980.et al (2014)

The work in this review focuses that flaxseed has nutritional and functional properties. country of
practical properties, flaxseed includes low portions of unfavorable healthful compounds inclusive of
cadmium, cyanogenic glycosides, inhibitors of trypsin which might be typically eliminated via thermal
and mechanical processes, consisting of cooking in microwaves, autoclaving and boiling.

4. Bernacchia R, Financial Sciences Laboratory, Department of Management, Sapienza University

of Rome, Via del Castro Laurenziano, 9–00161 Rome, Italy, Tel: 06/49.766.514;et al (oct 2014).

These review focuses on the recent data on flaxseed and its beneficial effects .Flaxseed is an annual
herb. It is a seed from the flax plant. flaxseed has high content of omega-3, omega-6 rich oil, alpha-
linolenic acid, lignans, etc.In year 2013-2014,Canada was world’s largest producer of flax about 614,000
metric tonnes of flaxseed.
5. Parikh M, Maddaford TG, Austria JA, Aliani M, Netticadan T, Pierce GN. Dietary flaxseed as
a strategy for improving human health. Nutrients. 2019;11(5):1171. doi:
10.3390/nu11051171.et al (2019)
The review focuses on the benefits of administering flaxseed or the individual bioactive
component on health and disease.flaxseed contain both soluble and insoluble fibres. Half an
ounce of dry flax provides 20% to 25% of your daily fiber needs.
PHARMACOGNOSY
TAXONOMY :
Flaxseed is the seed from the flax plant belonging to family linaceae
It is annual herb.
Classification of Flaxseed :
Vernacular name of flaxseed:

Hindi – Alsi, Tisi

Marathi –Alashi, Jawas, Atasi
Bengali – Masina, Atasi
Malayalam –Agastha, Agasi, Cheru, Charm
Kannada –Agasebeeja, Semeagere, Agasi
Panjabi – Alish, Alsi, Tisi
Oriya –Atushi,Peso
Sanskrit – Atasi, Jawas, Uma
Tamil-Alshi,Ali, Virai
Arabic- Bazrul karan, Bazruk Basen, Katan
Urdu –Alsi, Katan,
Deccan –Alshi, Jawas
Physical characteristics of flaxseed :

Colour –Reddish brown

Odour – Characteristic Odour
Shape – Oval and Strongly Fattened
Length – 4-6mm
Width – 2-3mm
Phytochemistry of Flaxseed:
It contain:
Proteins -20 %
Dietary fibre and Lipds -40%
Fatty oil – 37%
Carbohydrates -28. 8%
Fibre -4. 8%
Mineral matter -2. 4%
Calcium-0.17%
Phosphorus-0.37%
Iron -2.7mg%
It also contain Niacin, thiamin, Carotene, choline, pantothenic acid, and Vit. E
It Also contain Cinnamic acid, Flavonoids, phenolic acid and lignins
 Cotyledon contain 75% lipid and 76% Of protein while
 Endosperm contain 23% lipid and 16% of protein
NUTRITIONAL VALUE OF FLAXSEED
 Calories – 55g
 Fat -4.3g
 Sodium -3.1gm
 Carbohydrates -3g
 Fibre –2.8g
 Sugar-0.2g
 Protein -1. 9g
Carbohydrates :
 There are two different types of carbohydrates in flaxseed.
 Most of the carbohydrate in flaxseed is fiber (almost 3 grams in a tablespoon of whole flaxseeds).
 Fiber not only helps to boost digestive health, but fiberalso helps to regulate blood cholesterol and
boosts satiety—the feeling of fullness after eating.
 The rest of the carbohydrate in flaxseed comes from sugar, but it is a very small amount of naturally
occurring sugar.
Fats:
 There are just over 4 grams of fat in a tablespoon of whole flaxseed .
 The fat in flaxseed is primarily polyunsaturated fat, which is considered to a "good" fat.
 Polyunsaturated fat may boost heart health when you use it to replace less healthy fats (like
saturated fat) in your diet.
 There are two different kinds of polyunsaturated fatty acids (PUFAs) and flaxseed contains
both of them.
 You'll get 230 milligrams of α-linolenic acid (ALA) omega-3 fatty acids in a tablespoon of
flaxseed, and 606 milligrams of linoleic acid or omega-6 fatty acid, making these seeds a good plant-
based source of fatty acids.
 There is just under 1 gram of monounsaturated fat in a single serving of
flaxseed and a very small amount (0.4 grams) of saturated fat.
Protein:
 Adding flaxseed to a salad or smoothie can help boost your protein intake, but not substantially.
 Flaxseed's 2grams of protein per tablespoon is about 4% of your daily target (if you consume a 2,000
calorie-per-day diet).
Vitamins and Minerals

• Flaxseed provides important micronutrients.

• Thiamin is a water-soluble B vitamin that is needed by the body to metabolize carbohydrate
and branched-chain amino acids .
• It is also vital for neural function.
• A tablespoon of flaxseed also contains 2% of the DRI of niacin, vitamin B6, and folate.
• In terms of minerals, a tablespoon of flaxseed provides 13% of the DRI for manganese and
about 10% for magnesium.
• Other minerals in flaxseed include phosphorus (7% of RDI), copper (6%), and selenium (4%)
 Health benefits of flaxseed

1. Improve Hearth Health: It helps lower blood pressure and it may slow the progression of
atherosclerosis
2. Protect against Cancer: flaxseed show beneficial affect against prostate, lung, colon, ovary,
and liver cancer
3. Enhance the hair length
4. Flaxseed help for weight loss
5. High in omega 3 fatty acids- It contains high alpha-linolenic acid (ALA), a type of omega 3
fatty acids. That help to reduce inflammation and prevent cholesterol from being deposited in
your hearts blood vessels.
6. Rich in fiber Flaxseed contain two types of fiber Soluble and insoluble. Soluble fiber slow
down digestion, which may help to regulate blood glucose levels and lower cholesterol.
Insoluble fiber adds bulk to stool , which may prevent constipation and promote bowel
movement
Pharmacological Activity of flaxseed

Some Pharmacological Activity of flaxseed are as Follows:

1. Antiarrhythmic Effects
2. Antidiabetic Effects
3. Antioxidant Effects
4. Anticoagulant and Antiplatelet Effects
5. Antineoplastic Effects
6. Hormonal Effects
7. Antilipidemic Effects
Antiarrhythmic Effects:
 Flaxseed contains the high amount of Omega 3 fatty acids.
 Higher intake of dietary linolenic acid Reduce the risk of Arrhythmia.

Antidiabetic Effects:
 Flaxseed and flaxseed oil boast many health promoting compounds with the potential to lower
blood sugar level and delay the development of type 2 diabetes
 Flaxseed are rich In fiber, omega 3 fatty acids And unique plant components they may improve
blood sugar control , insulin sensitivity.

Antioxidant Effects:
 Secoisolariciresinol diglycoside (SDG), a plant lignan found in flaxseed, has been found to possess
antioxidant properties.
 Flaxseed may increase lipid peroxidation and thus may increase oxidative injury.
Anticoagulant and Antiplatelet Effects:
 Flaxseed oil decrease collagen stimulated platele aggregation and bleeding time .
 Use of flaxseed supplement also decrease thrombinstimulated platele aggregation.

Antineoplastic Effects:
 flaxseed was one of the most commonly used products for treating breast cancer.
 The amount of lignan production in processed foods is generally dependent on the percent of
flaxseed within the product.
 several researchers noted that the breast cancer- modulating effects of
phytoestrogens are dependent both on the background diet, genetic makeup, and on the timing of
exposure in the life cycle.
Hormonal Effects:
 Flaxseed (not flaxseed oil) is a rich source of plant lignans.
 It has been proposed that flaxseed and its lignans have potent antiestrogenic effects on estrogen
receptor-positive breast cancer.
 Enterlactone and enterodiol (metabolized from flaxseed in the bowel) may decrease cell proliferation
and inhibit aromatase, 5-alpha- reductase, and 17-betahydroxysterioid dehydrogenase activity, which
may offer a reduction in the risk of breast,prostate and other hormone sensitive cancers.
Antilipidemic Effects:
 It has been reported that defatted flaxseed (equivalent to the fiber component of flaxseed) can
significantly reduce levels of total cholesterol and low-density lipoproteins (LDL), and triglycerides.
 The fiber portion of flaxseed has been proposed to exert lipid-lowering effects by enhancing gastric
emptying time, altering transit time, interfering with bulk-phase diffusion of fat and increasing
excretion of bile acids.
Conclusion

Flax (Flax) has a potential health nutritional profile.

However, many people are still unaware of the potential health benefits of flax seeds and their
dietary uses.
The content of ALA (omega-3 fatty acid), fiber and lignan (especially SDG) attracts food
technologists to fully explore its possibilities in commercial food processing..
Flaxseed incorporates critical portions of compounds with purposeful and bioactive properties,
including alpha- linolenic acid, lignans, soluble fibre and protein, whose outcomes at the
prevention of sure nontransmissible continual illnesses had been tested.
These traits make flaxseed an appealing supply of purposeful components for the training of
foodstuffs.
Compounds including polyunsaturated fatty acids, crucial amino acids, nutrition E, lignans and
nutritional fibers help for human weight loss plan and fitness maintenance.
Results and Discussion
The result and discussion of review of flaxseed is based on recent survey as follow:
Survey :
Our project is based on a survey of flaxseed. For some questions, we have provided multiple marking
schemes. According to the survey, practically everyone is aware of flaxseed, its different uses and health
benefits of flaxseed.
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