_ Calayan Educational Foundation, Inc. (4 ® College of Medical Technology fiEam PACUCOA Accredited Level It a MTAP 101 A Midterm QUIZ CHE M 15" SEM SY. 2023-2024 Name: —— Score. Section: ___ 1 Multiple Choice. Shade the letter that corresponds to the best answer. Use only Black pen. Strictly no erasures. . -Precision’is attained when results are: a. Reliable . both accurate and reproducible ib) Reproducible d. accurate 2 Which of the following is{hatlconsidered as a|source of systematic error? x a. Deterioration of reagent e- improper calibration of the instrument “Sb, Sample instability Jat pipetting error 3. _Inyits hemolysis of sample can be brought by ‘a. Improper handling during centrifugation and separation . z b. Vigorous mixing of blood with anticoagu'ant c. Vigorous t fer of blood into the evacuated tube d> PL of the above Ge) None of the above - ; 4, Whieh of the followirg errors i& NOT considered a preanalytical error? a. During a phichotomy procedure, the patient is opening and clenching his fist multiple times. b. The blood was not permitted to clot and spun in a centrifuge after 6 minutes of collection: c._ The patient was improperly identified leading to a mis'abeled biood sample. The serum sempic was dilo'ed with tep water. © During phiebotomy, the EDTA tube was collected prior to the red. clot tube. 5. Ifthe patient's test a which of the following tubes should be tsedjto extract his blood? a.) EDTA c. non-additive B. Sodium fivoride tube 7 dd. serum separator tube\ 6. Which of the feiluwing is correctly matched? a. Blue quadrant : health hazards «. yellow quadrant: stability hazard b. Red quadrant: flammable hazards d. all of these 7.. For Class A fire, the type of extinguisher to be used is ~ a. Carbon dioxide extinguishers c, dry chemical extinguishers b. Pressurized water —-d-both-b-and 6— 8. is a type cf reagent that have been put through additional purification steps, they can be used if the test requires extremely pure chemicals ~ a. Analytical reagents d. Chemically pure reagents b_, Uttrepure reagents e. USP and NF grade ©. Technicel(Commercial Grade 9. This part of the spectrophotometer holds the solution to whose concentration is to be measured a.)Cuvet c. entrance slit b. Filters d. photodetector 10. is a substance or a solution that has a known concentration and is used in the calibration of an instrument. ~ a, Reagent . control b. Standard 4d, Reagent grade water 14. Which among ina purification techniques eliminate organic contaminants | a. Filtration c. Reverse osmosis b. Distitlation dyall of the choices 12: Which of the following centrifuges generate low speeds only but can produces a tighter pellet of _ precipitated cr clotted ce''s at the bottom of the tube? a, Horizontal head centrifuge c. ultracentrifuge b angle head centrifuge d. all of the choices 13. Which of the following measures the intensity of light?Calayan Educational Foundation, Inc. College of Medical Technology PACUCOA Accredited Level I! a,) Photometry ‘¢. nephelometry ‘4 vinci 4d, turbidimetry ich among the following wavelength is within the visible spectrum? <400 nm v o> 700mm — |P b. 650rm d. all of the choices 15, Which amsag the fo..owir.g Is. the formula used to calculate absorbance @. 2-log % transmittance b. 2=log ((Tl) x 100) ¢.-.2~log ((sample beam signe! / blank beam signal) x 100) G._-All of the choices ee 46. Which among the analytical techniques measures the amount ofiight reduced or blocked by particle formation (&) Turbidimetry c. nephelometry d. atomic absorption spectrophotometry “i. Spectrophotometry 47 when among the anaiftical techniques measures the emission of Hight that 028 from excitation of chemical or e'actrochemical compounds a. FEP c. nephelometry dd, atomic absorption ‘spectrophotometry b.> chemilumincescence Sc Which of the following regarding tourniquet application ig incorrect a/Cen be epplied for more than 2 minutes 5” Prolonged tourniquet application results to hemoconcentration * c. It should not be app’ ied for ammonia determination d. All of the chcices 4195The folowing analyte/s have, diurnal variation @ Growin hormone and iron b. Growth hormone only ¢.) growth hormone, iron, cortisol, and phosphorus 4. growth hormone, cortisol, and iron 20. in spectrophetometric analysis, what is the purpose of the reagent blank? ‘Correct for the interfering chromogens Correct for !'pemia Correct fo: protein Correct for color con's: Which glycoprotein binds with hemog} reticuloendothelial system? a,7 Haptogiobin b. Ceruloplasmin c. At-Antitrypsin 4. Fibrinogen — 22. is a system of creating and following procedures and Telable patient laboretery results. a. Quality Controt b. ISO certification 23. Quality assurance is concemed a. Pre analytical b. Analytical dal of the choices 24. Which types of quality contro! is performed periodically using provided samples of unknown concentration from reference laboratories? a. Internal quality control (c. external quality control b. Intra-Laboratory quay control «°° “all of the choices 25. is an error that occurs predictably once a pattern of recognition,is established. a. Random error ¢. allowable error b, Systematic error 4d. predictable error 26: i what condition would an increased level of serum a!sumin be expected? a. Malnutrition » uution of the reagents Jobin to facilitate the removal of hemoglobin by the b. c J. policies to aim for providing the most -¢, Quality Assurance d. NEQAS «with vhich phase of laboratory determination? c. Post analytical1 Educational Foundation, inc. [Mn ML College of Medical Technology [aM Fy PACUCOA Accredited Level I i! b. Acute inflammation (©. Dehydration ‘d Renal disease 27. Which of the following a an amonoacidopathy that has an absence offromogentisate oxidase fi the tyrosine pathway which leads to accumulation of homogentisic acid? <@ Niaptonuria 'b. Homocysteinuria ©. Maple syrup urine disease d. Phenylketonuria 28. What does hydrolysis of sucrose yield? a Glucose only b. Galactose and glucose . Maltose and glucose 4d, )Fructose and glucose 29° Which test may be performed to assess the aver during a previous.2- to 3smonth period? / ~~ a. Plasma glucose 7 b. Two-hour postprandial glucose c_ Oral glucose tolerance , Glycated hemoglobin sor Wnien glucose method is considered to be the reference method? a. Glucose cxidase ' 2b o-Toluidine % Hexokinase d. Gluccse dehydrogenase . 312A, cerebrospine! fluid specimen is sent to the Jab at 9:00 P.M, for glucose analysis. The specimen is cloudy and sppears to contain red blood cells. Which ofthe following statements is true? 4 Glucose testing cannot be performed on the specimen. b.)Specimen should be centrifuged and glucose assayed immediately. <<" Specimen can be refrigerated as received and glucose assayed the next day. Specimen can be frozen as received and glucose assayed the next day 32. What is the compound that comprises the majority of the|nonprotein-nitrogen fractions in serum? a. Uricacid b. Creatinine ¢. Ammonia 4, Urea _—— 33, Which of the following methods utilizes urease and glutamate dehydrogenase for the’ quantification of serum urea? a, Berthelot . B. ‘Coupled enzymatic ©. Conductimetric d. Indicator dye 34, Which of the following doesnot needito be done when collecting, handling, and using a specimen for ammonia analysis? a. Avoid using a hemolyzed specimen. Collect blood in EDTA or heparin evacuated tubes. é eyae specimen in a 37°C water bath immediately. ‘Advise patient not to smoke for 8 hours before blood collection. 35, What analyte is measured using the Jaffe reaction? a. Urea b. Uric acid ‘Ammonia [creatinine .a glucose level that an individual mai 5. (a.Calayan Educational Foundation, Inc. College of Medical Technology PACUCOA Accredited Level I! Pee tet thy most appropriate adult reference range for fasting blood glucose. 16 mg/dL (2.22-6.82 mmol/L) 60-140 mg/dl. (3.33-7.77 mmol/L) 5-99 mg/dL. (3.61-5.50 mmol/L) 75-150 mg/dL. (4.16-8.32 mmol/L) 37. Laboratory tests are performed on a postmenopausal, 57-year-old female as part of an annual physical examination. The patient's casual plasma glucose is 220 mg/dL, and the glycated hemoglobin (Hb AIC) is 11%, Based on this information, how should the patient be classified? a. Normal glucose tolerance b. Impaired glucose tolerance ¢.. Gestational diabetes mellitus d.) Type 2 diabetes mellitus 382% gout) what analyte deposits in joints and other body tissues? a. Calcium b. Creatinine cayrea (6. Drie acid 39 patient with hemoiytic-uremic syndrome ass although the plasma free hemoglobin is elevated and hemoglobinuria i Pr riate than hiaptogiobin to measure this patient's hemoltic episode? ciated with septicemia has a haptoglobin level that Is normal, resent. Which test would be more appr a. Hemopexin b.)-Alpha-1 antitrypsin QE Creactive protein d. Transferrin 40. Vinich of the following statements regarding proteins Is true? 4. Total protein and albumin are about 10% h’gher in ambulatory patients plasma total protein is about 20% higher than serum levels ‘accounts for about one-third of the cerebrospinal fluid total protein protein is about two-thirds of the serum total protein your answer sheet, write the conversion factor for the following Albumin normally Trensudative serous fl. ll. Identification. On the back of analytes. (Conventional units to/SLunits) 4. Albumin 2. Ammonia 3, Bilirubin 4. BUN 5) Cholestero! 6. Creatinine 7. 8, 9. 4 pee Glucose Total Protein Triglycerides 0.) Uric Acid‘Name: Section: Catayan Educational Foundation, nc. [os | College of Medical Technology figa] 7 r| PACUCOA Accredited Level I! MTAP 101 Midterm Exam, U Hen IST SEM S.Y. 2023-2024 Score 1 Multiple Choice. Shade the letter that corresponds to the best answer. Use only Black pen. Strictly no erasures. 1 Taft i ang oT HH mee 1¢ pipette should be allowed to drain and the last drop should remain in the pipette Co) The last drop is to be blown out after the pipette drains © The pipette is color coded 44. The pipette is a volumetric pipette 2. Agfertorin the analysishs detected, anda repeat analysis is required fat spesimenmust be used? a. New specimen to be collected immediately b. New specimen to be collected after 2 hours c__ New specimen to be collected after 1 day ‘Same specimen a 3."Wigorous hand exercise (fist lenching)decreases potassium, lactacte, and phosphate levels of the blood a. True ay & False 4Which among the following ir 01 jscorect a. Amount of light absorbed —<— 'b. Inverse logarithm of transmittance ¢ --Cannot be directly measured by the spectrophotometer ~ oa of the choices = 5, “Xolution in which molecules of solute inthe solution are in equilibrium with excess undissolved moleculestis referred to as: a._ Dilute oo Concentrated (cD Saturated SE supersaturated a ————— treasures solution composition based on the curentpotental lationship in anfelectrochemical cll] ‘when the potential is varied? - =—S—— a. Fluorometry b. Chemiluminescence c. Osmometry @ Voltammetry ) cause oferoqin phlebotomy islabeling = Short draw ©. overfilled tubes 4. wrong order of draw 8. Which among the following regarding capillary blood is‘ ‘a. Obtained by skin puncture « —S_ b. Mixture of venous and arterial blood “ e> May contain tissue fluids AAI of the choices o. Which among the folowing analytes affected by diumal variation arinereasedJourng the aftemgon? a. ACTH — b. Aldosterone c._ Cortisol’ ‘Iron ‘None of the above 10. Which among the following statements regarding venous blood isonet ‘a, Specimen of choice for most chemistry test 7 Contains products of metabolic activities of the different organs / Oxygenated bloodCalayan Educational Foundation, Inc. College of Medical Technology PACUCOA Accredited Level It 4. Obtained by venipuncture fe. All.are correct __ 11, The following nr cuss athens] Cause of a large (QB Pulling the plunger to fast eExpressing the blood forcefully into the tube 4. Bubble formation ©. Alcohol contamination 12, The following sample interferences are inherent to the patient xcept) a.) Hemolysis —— b. Tipemia cc. teterus & Allofthe above E_ None of the above | 15, Which among the following analytes are unstable Fmt removed from nto air 30 inst] Jetot after 30 minutes?) GO Glucose v G wes 'b,. Phosphorous “ge Potassium os of the above — © None of the above _ . anaes the amount of light jnsgnsity present over und? Fluorometry PQ Chemiluminessence ¢, Osmometry 4. Voltammetry . 1s. ymca procedure has a2 SD variasion fromasmsansuau. How 0" ‘ales From anormal population wil "SD include: ~ ' 33 a 68.27% >? by 84.76% \ > 95.45% © same : 16, Material with physi hem i esembling he eshanssines and consining concentrations of the sUBstaiice Being measured is known 9s: Control “S$. Standard ec. Calibrator 4. Reference solution 17, According "scale tires e aversely Froportionalto the concentration EB Directly proportional tothe concentration ~. Proportional to the square of the concentration (CB Proportiaga to the log % transmittance 18. Tw vn desirable for each general chemistry procedure. Which of these combinations would be Kk BBvaner 4 the 2 ‘Mean of normal range ang abnormal (high) b. High normal range and abnormal (high) a {S5,bow normal range and abnormal (low) J 7 ? Abriormal (low) and abnormal (high) hould be used with all procedures to determine: 4. Coefficient variation 20. Which ofthese substances annote presorved i fiszing? 4) Blood urea nitrogen . b. Creatine kinase isoenzyme © Lactate dehydrogenase d. Prostatic acid phosphataseCalayan Educational Foundation, Inc. College of Medical Technology PACUCOA Accredited Level It Prevent glycolysis, 6. »Prevent conversion of prothrombin to thrombin c. Chelate calcium . Bind calcium \ — 22, The}precaution}o be followed with 1a specimen for bilirubin determination isto: Protect from light : —————————— 2 Refrigerate 3. Cap and refrigerate _~4 Freeze immediately & / Lonly Land 2 ce. land3 4. land4 e. land 2 or 4 23. Bthylenediamine tetraacetic acid [EDTA] works as anticoagulant by: a. Prevent glycolysis Sb. Prevent conversion of prothrombin to thrombin Chelate calcium: ‘d. Bind calcium f._Nome of the choices +24, In the laboratory procedure for the 1 precipitate all Apo Al containing lipoproteins Covert cholesterol esters to cholesterol for detection Precipitate all Apo Band Apo A ‘containing lipoproteins Prosiptae all Apo B containing proteins ich of the following lipoproteins is ‘the smallest of all the lipoproteins and is composed ) HDL Chylomicrons c.) LDL ._ Triglycerides 26, Which of the following would be most adversely affected b a HDL b. LDL Cholesterol riglycerides 27° Which ofthe ‘aia found poundiniDLasndLDain and pasa and aso conver free G Cholesterol esterase b. Cholesterol oxidase ) Lecithin-cholesterol acyltransferase Lipase: { nonfasting Sample? 28. A patient presents to his physician for a lipid profile. The following results are received: _o HDL = 50 mg/dL Total cholesterol = 300 mg/dL w ‘Triglycerides = 200 mg/dL. The galeulated LDL cholesterol is 0 + 200 /s) a_ 200 , Q 20 , 290 4. 350 29. Which enzyme is ; wfeianeonl common to all enzymatic methods for{triglycerid# measurement? ——IC] Calayan Educational Foundation, inc. College of Medical Technology PACUCOA Accredited Level I! hi 4, blycerol phosphate oxidase ‘b. Glycerol phosphate dehydrogenase c._ Pyruvate kinase (@)Giyeerol kinase _ 30. A patient sample is assayed foifasting triglyceride) and a triglyceride value of 1036. mg/dL. This value is of immediate concern because of fi SSsocTation with which of the following a, Coronary heart disease b,_ Diabetes © Pancreat a. Gout 31. What is thfmost appropriate fasting)procedure when a lipid study oF genes al choles HDL. nd LDL tests are ordered? “a. hours, nothing but water allowed b. 10 hours, wafer, smibking, coffee, te (no sugar or cream) allowed >> 12 hours, nothing but water allowed - 4. hours, wate, smoKing, coffee, 186 (no sugar or cream) allowed 430, Joka Smithers (2 years of age) i in to see his physician fora pre-college physical and cheekypy ohn Tras always been extremely healthy. The following laboratory results are received: cv =~ hu ‘AStandard = 0.679 ‘AControl = 0.650 As ASmithers=0.729 7 CStandard=200 mgidL 5p Control range 190-195 mg/dL 2 Deng 20 Z malt ‘ohn’ cholesterol concentration is jppreximately =e ~ a. 186 mg/dL a b> 199 modL. “ec. 209 mg/dL | © 215 mg/dL _——=— 54 -Which among the following elements in proteins]differentiatethis.class of substan es from carbohydrate and lipids? ~— — a. Carbon b. Hydrogen Nitrogen Oxygen 34. Which among the following igtrue about-al J ‘a. Compared to globin, it makes up the lessgr portion of total protein ~ >. Its size prevents its passage through even a damhéged glomerular barrier @ tis produced in the liver ° usually related to High serum values y n electrophoresis at pH 8.6 is: ve y a. Alpha | globulin AB ovedé G@) Albumin 2 ._ Beta globulin B B 4.) Gamma globulin aaa __, &- Cathe 36. “The process of separating albumin from globulins using} fecium sulfate js known as: a. Floaiafion SSS ——— Protein precipitation .) Salting out “d. Ultracentrifugation 37. The of protein nitro n ‘The gpussin of ps tein nitrogen contant to protein content depends on the fact Gb) 6.54 E>) 6.63 | d. 7.78 38, Which reagent is employed in the serum protein determination? a. Molybdenum blue =—=—==-_— b.. FerricyanideCalayan Educational Foundation, Inc. College of Medical Technology PACUCOA Accredited Level I! Resorcinol-HCI Biuret 30.°X normal serum electrophoresis has approximately 6096 albumin and 5-10% each of the other 4 fractions. If an electrophoretic pattern shows 30% albumin, 4-10% ‘STother fractions excepyfgamimia which is yaSvG] ypu would ‘expect what condition to exist in the patient? A Cirrhosis: av a Ge Monoctonal gammopathy c. Inflammation 4. Chronic lymphocytic leukemia 40, By theurease metho) urea is enzymatically converted to: © Ammonia Carbon dioxide c. Nitrogen 4. Amino groups , 41.U i of clev ated which of the following? ydney failure ~ Cirrhosis of the liver @ Muscle destruction Intestinal blockage / 42. Theffirst step in analyzing a 24-hour urine specimen for, cuantiative wine protein a. “Subculture the urine for bacteria — 'b. Add the appropriate preservative Screen for albumin using a dipstick Nec te ota volume at 45, Toe biuret ragtgn forthe analysis of serum protinepends on iQ number of 2 eine pow Uk Frc arbo! ours \c, Peptide bonds d. Tyrosine residues 44 Tagellulose aceuteletrophoresis at pELB.6 of serum proteins will show an order of migration beginning with be es a as follows: (> Albumin, alpha-1 globulin, alpha-2 globulin, beta globulin, gamma globulin SS Alpha-1 globulin, alpha-2 globulin, beta globulin, gamma globulin, albumin ‘c. Albumin, alpha-2 globulin, alpha-t globulin, beta globulin, gamma globulin 4 Gamma globulin, beta globulin, alpha-2 globulin, alpha-! globylin, albumin 45. Which of the following serum protein fractions is most likely to bg plevated)in patients with nephrotic syndrome? a. Alpha-1 globulin 4 bh, Albumin (CZ Alpha-2 globulin a globulin and gamma globulin 46, Suerosefs considered a disaccharide that on hydrolysis yields which ofthe following sugars? ‘a Glucose b. Galactose and glucose ¢_ Maltose and glucose [oy Fructose and glucose ——= 47° The following results are from a 21-year-old patient with a back injury whafappears otherwise healthy), Whole blood glucose: 77 mydl (4.2 mmol) —— Serum glucose 88 mg/dl (4.8 mmol/L) CSF glucose: 56 mg/dl (3.1 mmol/L) § The best interpretation of these results is that: The whole blood and serum vale ae expacnd bt the CBF values elevated ‘The whole blood glucose should be higher than the serum value © A\ll values are consistent with a normal healthy iualCalayan Educational Foundation, Inc. [qf | College of Medical Technology faa it | PACUCOA Accredited Level II 7 d. The serum and whole blood values should be identical x 48, A person with a blood glucose of 80 mg/dl (4.4 mmol/L) would have a imultaneously determined CSF glucose value off - 25 mg/dl (1.4 mmol/L) go. (50 mg/dl (2.3 mmol/L) 6 ©. 100 mg/dl (5.5 mmol/L) ato? d. 150 mg/dl (8.3 mmol/L) 49, Which ofthe biochemical processes below is promoted by a. Glycogenolysis b. Gluconeogenesis ¢, Esterification of cholesterol |.) Uptake of glucose by the cells 0 Taboratory results for a patient 2 diabetes/ire as follows: Analyte Result Glucose 128mgidL 4 Total cholesterol 195 mg/dL HDL 45 mg/dL LDL 105 mg/dL. BUN 38 mg/dL Creatinine 2.1 mg/dL Microalbuminuria s4mpmt& AST 28 U/L ALT 38 U/L Ah of the following statements is correct regarding this patient? ax increased risk for cardiovascular disease increased risk for diabetic nephropathy = patient is at increased risk for liver failure Patient is at risk for hypoglycemia 51 ar what serum slusose concentration woud glucose begin Qjpppear in he net) 2 s0mgdl eae ; b. 75 mg/dL y J 100 mg/dL. @ 170 mga —— _ srl obese woman visits her doctor reportngfinereased urination especially at nigh) Gineased his td creased appetite, Her glucose on examination was 21 mpl (esting). Which ofthe following Satemen best fis with the g information above? ‘a. The patient most likely has type | diabetes mellitus As) The patient would show a positive glucose in her urine ‘The patient would have a Secbnses glycated hemoglobin ~< c d. Additional testing of this patient should include assessment ‘of hyjpoglycemiag 53, A plasma glucose result is 100 mg/dL. The corresponding glucose in. whol ‘would approximate: a. 58mp/dL oc, 98 mg/dL 87 mp/dL. L114 mg/d 54 Which of the following methods is virtually specific for glucose and ong GoPD a second coupling step requiring magnesium? aad @ Hexokinase ¢, Glucose dehydrogenase b. Glucose oxidase 4. Pyruvate kinase 55. Which of the following precautions is necessary to ine ait fi use 2 3s, 180 gramlday carbohydrate dit for 3 days prior fo'the test = (Co) a tasting state before glucose is given “G. No undue stress before or during the test @ alllofthe above None of the above = 56. A 62-year-old patient presents to the physician with report offnereased thirst and increased. urination} particular at night. The physician requests a series of tests over the next few days. The following data are received: ° oDCalayan Educational Foundation, Inc. College of Medical Technology PACUCOA Accredited Level I! Analyte Result Random glucose 186 mg/dL Fasting glucose 114 mg/dL 2-Hour OGTT 153 mg/dL HbAle 5.9% v Which ofthe following conclusions may be made regarding these data? Data represents normal glucose status Orn represents an impaired glucose tat = Data represents the presence of an insulinoma d. Data represents the diagnosis of diabetes -—_— foest marketo detect patients with diabetes who are at risk for 57, Which of the following laboratory tess is th¢ best ma devel tee oho mcd wy oe roalbuminuria test a > a, Creatinine jlucose b. BUN _ ; ; on 58, Th red complex veloped inte Jaffe method determine creatinine measurements isa result of the xi ‘nine with which of the following? z > splexing of creatinine wit sortie wit ‘Alkaline picrate ¢. Sulfurie ac b. Diacetyl monoxide d, Sodium hydroxide : __ tel nce corrected for body surface area approximates [ . 59, Given the data below, the calculated creatinine. le Ulan %9 NSP swe — 11.2 min SL Result Ui Analyte ‘p Serum creatinine 1.2 mg/dL “Urine creatinine (120 mg/dL |, Urine volume whit) 1 a5-bAden vid min /\ Surface area 1,80 m2 , (> Satie \ Vn < c. Kjeldahl a.Nessier (077 cerformed. The 24-hour volume of urine is 770ml; serum creatinine is 2/0 mg/dl and is cleared per minute assuming average 2 7 4 Cc J? te Opal GB 0 @ . Lloyd 61. A creatinine clearance testis p ‘urine creatinine is 240 mg/dl. What is the (body surfacd? P= 2.0 ay/dl 20nd ph 05 a. 60 U2 2g ML Dib s Boe West ec 18 62° Which formula is most accurate in predicting-plasianasmpolality? Od Vv IPmL est? ‘a. Na+2(Cl) BUN +Glucose ri — SAPGO min L ° b.__2(Na) +2 (Cl) +Glucose + BUN Cie Taio)? - ay (Na) +Glucose/18 +BUN/2.8 % 2(BUN) +Glucose/18 + CV2.8 166 J ob 63. Which of the following statements regarding eum wee true? ‘a, Levels are independent of diet - , High BUN levels can result from necrotic liver disease BUN is elevated in prerenal as well as renal failure ‘d. BUN rises earlier and quicker than creatinine in renal damage 64. A patient with type 2 diabetes isin for a routine examination with the _A series of laboratory tests are performed, including calculation of an eGFR. The patient’s calcul: eG! mL/ min, }this result is most indicative of: a. A normal state Mild kidney damage b. Abnormal glucose control d. Kidney failure 65. A healthy 28-year-old female sees her physician fo ji i elatively” i le iysician for a routine examination and receives a “relatively” cl ill health except for the results below. anit Total bilirubin 2.8 mg/dL (91! I.2ny wo)Calayan Educational Foundation, Inc. (ei) College of Medical Technology PACUCOA Accredited Level I! Direct bilirubin 0.1 mg/dL. < O-ny/4L Indirect bilirubin 2.7 mg/dL. OZ. O-8 mopil ‘These results most likely indicate which of the following? ‘4. Normal bilirubin metabolism X b. Extrahepatic obstruction a Doact /Coniegnled ¢, Dubin-Johnson syndrome 4 10/7 A viect /eonivgate (2) Gilber’s disease Be indiect/vmeonygone measure of advanced stages, Poor «66. Which ofthe following is measured.vsing glutamate dehydrogensse and is 8 & soar comin Wer TeTiver disease c. unconjugated bilirubin Total bilirubin o> Ammonia dren ee —_ 67 In which of the following disease states would you see an blevation in total bilirubin ‘and conjugated bilirubi a) only? ewe ———— Biliary obstruction «e. neonatal jaundice increased unconjugated ——— Hemolysis _ ; 68. Inwhich of the following conditions doesfio 2c ‘of giucurony! transferase Fest! te in and kerioters in neonates and eventual death within 18 months? a. Gilbert's disease Coen syndrome 'b, Dubin-Johnson syndrome [ Intravascular hemolysis . i ign ofb into the ile canal) p 69, Which of the following conditions is caused by de a. Gilbert's disease 'b. Physiologic jaundice of th 70. Which of the following enzym a. Biliverdin reductase "Dubin-Johnson syndrome e newborn ic jaund 1s is responsible for’ = glucurony! transferase d. b-Glucuronidase b. Peroxidase 171, which ofthe following fractions of bilirubin in high concentrations /$ associated wit 7 a. Delta bilirubin = = Conjugated bilirubin —s (b>) Unconjugated bilirubin ____ 4 Unconjugated and delta bilirubit 72 After a difficult venipuncture requiring/prolonged torniquet applicat jon} the serum K. was found to be 6.8 mEq/l. ‘The best course of action is t0: a. Repeat the test using the same specimen +. Adjust the volume based on the current serum Na © Repeat the test using freshly drawn serum C B, in a spectrophotometer utilizing a ¢, Holmium oxide glass d, Potassium dichromate solution Nickel II sulfate ’. Mercury vapor lamp 74, In measuring calcium using AAS, anthanumjis used: a. Asan intemal standard _b. To bind calcium }) As diluents to bind phosphorus d. To eliminate protein as interference 75, Barbiturate abuse can-be detected using immunoassays a8 screening method, which among the following is used _g\gonfib the presence of barbiturates i urine samples? © : Ca) GMS — ©. TLC helometry 4d. Ultraviolet absorpti . on |. Ultravi tion spectros 76[Cgulometry}js often used to measure: re as '@,_ The pH in saliva . Bicarbonate in urine (ox off b ore newest d. Ammonia in plasma jich among the fol lowing is the moss specifi metho for thy si i L. Glucose oxidase - sis of luose @) Herokinase ¢. Glucose-6-phosphatase 4. Glucose dehydrogenase48, The most a. Jaffe reaction a—Natelson 6, Pvlenderson-hasselbalch 802 Which of the following is t 1 -log(%T) (2) 2 -log(*T) fog(%T) +2 d. 2x log(%T) e. None of the choices PACUCOA Accredited Level d. 8hydroxyquinoline reaction .Schales and schales method __ 79. Tha bicarbonate and carbonic acid rai calculate from an equation by a ¢. Gibbs-Donnan 4. Siggaard-Andersen ven the percet fhe formula for calculating absorbance 1, Which among the following isthe equation used in csi a.) pka= pH + log({acid)/{salt]) iy to K bb. pKa=pH + logt (sal pH = pKa + logi{acid) pH = pKa + log({salt/{acid)) “g.. none of the choices 82 is a systemat Trend shift 8. &_Trend Sshitt 3 is a Standard deviation b. Variance Level HAL A is a systematic error that is caused by| facidl) ott V{salt]) ot + 193 Rts Ge oaepsvndo determie whethes the nati proses teard multirles ‘4. coefficient of variation o | Control: Calcium Mean 8.2 mgidi's* 0.31 College of Medical Technology nsmittance of a solution? 1¢ instrument 5s is out of control‘al Technolog) sy PACUCOA Accredited Level I dur of the of the previous paj month, ie and identify the QC problem Taare QC problem that occured )Trend -cvosses the ren .random error feferring to the Levy—Jennings chart, what is o Kertosia what is the first day in the mo radon ult shouldbe epee) day in the month when the run should be rejected and a. Days — © —— b oy S CRoDay 8 - YH day above me Day ‘a. Day 9 87, Referring to the Levy—Jennings chart, what anal is pres G@)snin : en ce daring to ssond half ofthe month? B. Trend 4. Kurtosis 88,_What i the first day inthe second half ofthe month that pajeat jesus would besejestes. a. Day 16 CopDay 18 T% doy below the mean b. Day 17 4. Day 19 89. A quality control: material should: a.) Behave like a real sample Available to last for 2 to 3 months ¢. Should vary in concentration and composition from vial to vials 4d. May have a maximum of 2 communicable diseases Ce.) All of the choices 90. Which of the two tyj control concentration fromigeference laboratories?) / a. Internal quality control 'b. Intra-Laboratory quality control ally using provided samples of unknown sternal quality control d. all of the choices I. Tdentification, On the back of your answer sheet, write the conversion factor forthe following analytes (Conventional units to SI units) 1.Albumin eo ALB i 2Ammonia 0-597 pot Me 3.Bilirubin ' Hb ° 4,BUN Gl 5.Cholesterol G Chole 6.Creatinine TG 7.Glucose 0.0585 8, Total Protein But 9. Triglycerides Bun 10, Uric Acid 0 Ereannine brie Ampeg so