SAFETY DATA SHEET GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA

according to Regulation (EC) No. 1907/2006

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : 1,2,4-Trichlorobenzene

CAS-No. : 120-82-1

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Scientific research and development, Intermediate
1.3 Details of the supplier of the safety data sheet
Company : CHANGZHOU SMART SOURCE INTERNATIONAL CO., LTD
605,Block #16-1, Landsea Green Town,
Xinbei District,
Changzhou 213022,
Jiangsu, China

Telephone : +86 519 85263898

Fax : +86 519 85263899
1.4 Emergency telephone
Emergency Phone # : +86 519 85263898

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Skin irritation (Category 2), H315
Short-term (acute) aquatic hazard (Category 1), H400
Long-term (chronic) aquatic hazard (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008

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 Pictogram

Signal word Warning

Hazard statement(s)
H302 Harmful if swallowed.
H315 Causes skin irritation.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel
unwell.
P302 + P352 IF ON SKIN: Wash with plenty of water.
Supplemental Hazard none
Statements
Reduced Labeling (<= 125 ml)
Pictogram

Signal word Warning

Hazard statement(s) none
Precautionary none
statement(s)
Supplemental Hazard none
Statements
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.1 Substances
Formula : C6H3Cl3
Molecular weight : 181,45 g/mol
CAS-No. : 120-82-1
EC-No. : 204-428-0
Index-No. : 602-087-00-6
Component Classification Concentration
1,2,4-trichlorobenzene
CAS-No. 120-82-1 Acute Tox. 4; Skin Irrit. 2; <= 100 %
EC-No. 204-428-0 Aquatic Acute 1; Aquatic
Index-No. 602-087-00-6 Chronic 1; H302, H315,
H400, H410
M-Factor - Aquatic Acute:

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 10
For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first-aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Hydrogen chloride gas
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.

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SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance
contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency
procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only
to qualified or authorized persons.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls

Personal protective equipment

Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Viton®
Minimum layer thickness: 0,7 mm
Break through time: 480 min

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 Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 10 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
Body Protection
protective clothing
Respiratory protection
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic
compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear
Color: colorless
b) Odor aromatic
c) Odor Threshold No data available
d) pH No data available
e) Melting Melting point: 17 °C
point/freezing point
f) Initial boiling point 213,5 °C at 1.013 hPa
and boiling range
g) Flash point 113,0 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, No data available
gas)
j) Upper/lower Upper explosion limit: 6,6 %(V)
flammability or Lower explosion limit: 2,5 %(V)
explosive limits
k) Vapor pressure 1,3 hPa at 40,0 °C
0,26 hPa at 20 °C
l) Vapor density No data available
m) Density 1,45 g/cm3

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 Relative density No data available
n) Water solubility 37,8 g/l at 25 °C
o) Partition coefficient: log Pow: 4,05 at 25 °C - Potential bioaccumulation
n-octanol/water
p) Autoignition 571,0 °C
temperature
q) Decomposition No data available
temperature
r) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available

SECTION 10: Stability and reactivity

10.1 Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Exothermic reaction with:
Oxidizing agents
Alkali metals
Alkaline earth metals
Risk of explosion with:
fire-promoting substances

10.4 Conditions to avoid

Strong heating.
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
Oral: No data available
LD50 Oral - Rat - male and female - 930 mg/kg
(OECD Test Guideline 401)
Inhalation: No data available

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 LD50 Dermal - Rat - 6.139 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Convulsions or effect on seizure threshold.
(RTECS)
Skin corrosion/irritation
No data available
Skin - Rabbit
Result: Moderate skin irritation
Remarks: (RTECS)
(Regulation (EC) No 1272/2008, Annex VI)
Serious eye damage/eye irritation
No data available
Eyes - Rabbit
Result: No skin irritation - 24 h
(OECD Test Guideline 405)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative
(OECD Test Guideline 406)
Germ cell mutagenicity
No data available
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Carcinogenicity
No data available
Reproductive toxicity
No data available
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
RTECS: DC2100000
Nausea, Dizziness, Headache, Gastrointestinal disturbance, Liver injury may occur., Kidney
injury may occur.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.

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SECTION 12: Ecological information
12.1 Toxicity
No data available
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 1,4 mg/l - 48 h
and other aquatic (OECD Test Guideline 202)
invertebrates
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) -
1,4 mg/l - 96 h
(US-EPA)
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Other adverse effects
No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.

SECTION 14: Transport information

14.1 UN number
ADR/RID: 2321 IMDG: 2321 IATA: 2321
14.2 UN proper shipping name
ADR/RID: TRICHLOROBENZENES, LIQUID
IMDG: TRICHLOROBENZENES, LIQUID
IATA: Trichlorobenzenes, liquid
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
14.6 Special precautions for user
No data available

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SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use
REACH - Restrictions on the manufacture, : 1,2,4-trichlorobenzene
placing on the market and use of certain
dangerous substances, preparations and articles
(Annex XVII)

National legislation
Seveso III: Directive 2012/18/EU of the European : ENVIRONMENTAL HAZARDS
Parliament and of the Council on the control of
major-accident hazards involving dangerous
substances.

Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or
stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of H-Statements referred to under sections 2 and 3.
H302 Harmful if swallowed.
H315 Causes skin irritation.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.
Further information
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product.

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