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Basharat Ali

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Basharat Ali

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Uploaded by

Talha Gaming
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Dr.

Basharat Ali (HEC Approved Supervisor)


Assistant Professor of Chemistry
SA-Centre for Interdisciplinary Research in Basic Sciences (SA-
CIRBS)
International Islamic University, Islamabad.

051-9012937
[email protected] ;
Specialization: Organic, Bioorganic and Medicinal Chemistry
Education and Training:
Post-Doctorate: Department of Medicinal Chemistry, Soochow
University, China (June 2019-May 2020)
Research Assistant: Department of Polymer Science and Engineering,
Zhejiang University, China (October 2017-December 2018)
Ph.D. in Organic Chemistry: H. E. J. Research Institute of Chemistry,
University of Karachi, Pakistan (2018)
M.Sc. in Chemistry: Department of Chemistry, Federal Urdu
University of Arts, Science, and Technology, Karachi (2012)

Profile:
Dr. Basharat Ali joined Centre for Interdisciplinary Research in Basic Sciences (CIRBS), International
Islamic University, Islamabad in February 2021. He completed his PhD in Organic Chemistry from
HEJ Research Institute of Chemistry, ICCBS, University of Karachi. During his PhD he worked on
synthesis of hydrazones, thiosemicarbazides, 1,2,4-triazoles and other heterocyclic compounds. He
worked as Research Assistant at Department of Polymer Science and Engineering in Zhejiang
University, China. He worked on organometallic catalysis for polymer synthesis, and synthesis of
Organic Solar Cells. During Post-Doctorate in the Department of Medicinal Chemistry, Soochow
University, China he worked on synthesis of chemiluminescent dioxetane probes, fluorescent probes,
and synthesis of anthraquinone (Rhein and Emodin Natural Products) derivatives.
Research Interests and Focus:
My research focuses on design, synthesis, characterization and biological evaluation of medicinally
important synthetic small molecules, particularly, in the field of heterocyclic chemistry. My research
focus also includes design and synthesis of probes for diagnosis of human diseases and detection of
toxic compounds and metals.
Research Grants:
SRGP research grant (Rs. 1.0 million) from Higher Education Commission, Synthesis,
Characterization, and Evaluation of 1,3-Thiazole Derivatives as Antimicrobial and Bioactive
Agents.(P.I: Dr. Basharat Ali, Co-PI: Prof. Dr. Muhammad Riaz)
Research Students:
MS Research Student
Student name Status
Kiran Fatima Iqbal Completed
Sammiah Tariq Completed
Sunmbal Shaheen Completed
Muhammad Ishaq Completed
Nabeel Ahmed Completed
Bibi Hadiqa Completed
Fareeha Khan Completed
Zunaira Rehman Completed
Muhammad Masood Completed
Nadir Rasheed Completed
Muhammad Mueen Completed
Mansoor Hussain Completed
Ikram Ullah Research
Kamran Sadiq Research

Selected Research Publications:


1. Zhou, S., Mou, Y., Liu, M., Du, Q., Ali, B., Jurupula, R., Qiao, C., Hu, L.F.and Ji, X. (2020).
Insights into the Mechanism of Thiol Triggered COS/H2S Release from N-Dithiasuccinoyl
Amines. The Journal of Organic Chemistry, 85(13), 8352-8359
2. Ali, I., Rafique, R., Khan, K. M., Chigurupati, S., Ji, X., Wadood, A., Rehman, A., Perveen, S.,
Ali, B. Potent α-Amylase Inhibitors and Radical (DPPH and ABTS) Scavengers based on
Benzofuran-2-yl(phenyl)methanone Derivatives: Syntheses, In Vitro, Kinetics, and In Silico
Studies, (2020). Bioorganic chemistry, 104, 104238
3. Naz, F., Kanwal, Latif, M., Salar, U., Khan, K. M., al-Rashida, M., Ali, I., Ali, B., Taha, M., and
Perveen, S. (2020). 4-Oxycoumarinyl Linked Acetohydrazide Schiff bases as Potent Urease
Inhibitors. Bioorganic Chemistry, 104365
4. Abbas, A., Ali, B., Khan, K. M., Iqbal, J., ur Rahman, S., Zaib, S., and Perveen, S. (2019).
Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and
kinetic studies. Bioorganic chemistry, 82, 163-177
5. Ali, B., Khan, K. M., Salar, U., Hussain, S., Ashraf, M., Riaz, M.,Wadood, A., Taha, M. and
Perveen, S. (2018). 1-[(4′-Chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives as
potent urease inhibitors: Synthesis, in vitro and in silico studies. Bioorganic chemistry, 79,
363-371
6. Ali, B., Khan, K.M., Hussain, S., Hussain, S., Ashraf, M., Riaz, M., Wadood, A. and Perveen,
S., (2018). Synthetic nicotinic/isonicotinic thiosemicarbazides: In vitro urease inhibitory
activities and molecular docking studies. Bioorganic chemistry, 79, 34-45
7. Li, S., Zhan, L., Zhao, W., Zhang, S., Ali, B., Fu, Z., Lau, T.K., Lu, X., Shi, M., Li, C.Z. and
Hou, J., (2018). Revealing effects of molecular packing on the performances of polymer solar
cells based on ADCDA type non-fullerene acceptors. Journal of Materials Chemistry A, 6,
12132-12141
8. Hashim, J., Arshad, N., Khan, I., Nisar, S., Ali, B. and Choudhary, M. I. (2014). Preparation of
dihydrotetrazolo [1, 5-a] pyrimidine derivatives from Biginelli 3, 4-dihydropyrimidine-2-
thiones. Tetrahedron, 70(45), 8582-8587.

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