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Basic Bioinformatics Syllabus

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40 views

Basic Bioinformatics Syllabus

Uploaded by

banjaraarush09
Copyright
© © All Rights Reserved
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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SAGE University,

Indore

Institute Name: Institute of Biological Department Name: Institute of Biological Sciences


Sciences
Recommended Programs: B.Sc

Course Name B.Sc Course Code BLSDSBMB008P


L T P N
Credit Hours Total Credits
- 2 - 2
-
Prerequisites BASICS BIOINFORMATICS
Bioinformatics is defined broadly as the study of the inherent structure of biological
information. It is the combination of biology and the information sciences. Examples of
current bioinformatics research include the analysis of gene and protein sequences to
reveal protein evolution and alternative splicing, the development of computational
Course approaches to study and predict protein structure to further understanding of function, the
Objectives analysis of mass spectrometry data to understand the connection between
phosphorylation and cancer, the development of computational methods to utilize
expression data to reverse engineer gene networks in order to more completely model
cellular biology, and the study of population genetics and its connection to human
disease.
1. Sequence information resource NCBI.
2. Understanding and use of various web resources: EMBL, Genbank, Entrez,
UniPROT.
3. Protein information resource (PIR)
4. Sequence and protein submission tools.
Course Content 5. Understanding and using: PDB, Swissprot, TREMBL
6. Using various BLAST and interpretation of results.
7. Retrieval of information from nucleotide databases.
8. Multiple sequence alignment using Clustal W.
9. Homology Modelling.
10. OMIM Database
 Mount D., Bioinformatics: Sequence and Genome Analysis, Cold Spring
Harbor Laboratory Press, New York. 2004
 Leach, A. R., Molecular Modelling: Principles and Applications, Longman,
1996.
Text Books
 Cynthia Gibas and Per Jambeck, Bioinformatics, 1st Edition, O’Reilly
Publication, 2001.

 University Of Surrey. June 25, 2007. In Silico Cell For TB Drug


References Discovery. ScienceDaily. Retrieved February 12, 2010.
 Athanaileas, Theodoros; et al. (2011). "Exploiting grid technologies for the
simulation of clinical trials: the paradigm of in silico radiation
oncology". SIMULATION: Transactions of the Society for Modeling and
Simulation International. 87 (10): 893–
910. doi:10.1177/0037549710375437. S2CID 206429690.
On completion of this course a student should be able to understand
1. Become familiar with the essential concepts of bioinformatics.
2. Explore the history of this young area.
Course 3. Experience how rapidly bioinformatics is growing.
Outcomes 4. Insilico Prediction.
5. Computational Biology

Mapping of Course outcome with Program Outcomes, PSO’s, and Knowledge Levels
(As per Blooms Taxonomy)
Knowledge Levels
CO/PO PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11 PO12 PSO1 PSO2 PSO3 PSO4
(K1, K2, …, K6)
CO1
CO2 Y
CO3 Y
CO4 Y

High-3 Medium-2 Low-1

K1 => Remember K2 => Understand K3 => Apply K4 => Analyze K5 =>


Evaluate K6 => Create

Prof. Prof. Dr.


Designed By: Checked By: Approved By:
(Dr. Lakshmi Pillai) (Name with Sign.) (Name with Sign.)

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