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General Biology 1 (Lecture)

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General Biology 1 (Lecture)

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CELL DIVISION

• process of producing another cell from pre-existing cells, cell divides into 2 new cells
WHY DO CELLS NEED TO DIVIDE?
• Living things grow by producing more cells, NOT because each cell increases in size
• Repair of damaged tissue
• If cell gets too big, it cannot get enough nutrients into the cell and wastes out of the cell
• The original cell is called the parent cell; 2 new cells are called daughter cells
• Many organisms, especially unicellular organisms, reproduce by means of cell division – called
asexual reproduction – Ex: bacteria
DNA
• located in the nucleus and controls all cell activities including cell division
• Long and thread-like DNA in a non-dividing cell is called chromatin
• Doubled, coiled, short DNA in a dividing cell is called chromosome
- Consists of 2 parts: chromatid (1) and centromere (2)
CELL CYCLE
• series of events cells go through as they grow and divide
INTERPHASE
• period of cell growth and development, replication/copying, cell also grows, carries out
normal cell activities, replicates all other organelles
MITOSIS
• division of the nucleus into 2 nuclei, each with the same number of chromosomes, occurs in
all the somatic (body) cells
PMAT
• Prophase - coil up, nuclear envelope disappears, spindle fibers form
• Metaphase (Middle) - line up, connect
• Anaphase (Apart) - divide, opposite poles
• Telophase (Two) - uncoil, nuclear envelopes form, 2 new nuclei, spindle fibers disappear
CYTOKINESIS
• division of the rest of the cell (cytoplasm and organelles) after the nucleus divides (then back
to interphase)

• Somatic Cells are “body” cells and contain the normal number of chromosomes….called the
“Diploid” number (the symbol is 2n). MITOSIS
• Gametes are the “sex” cells and contain only ½ the normal number of chromosomes…. called
the “Haploid” number (the symbol is n). Sperm, Testes. Ovum, Ovaries. MEIOSIS
MEIOSIS
• Meion which means reduce, two stages: Meiosis I - reductional division; Meiosis II -
equational division
INTERPHASE
• Pre meiotic interphase
MEIOSIS I
• Prophase I
- Leptotene/Leptonema - begin to condense, increase in nuclear volume
- Zygotene/Zygonema - pairing between homologus chromosomes
- Pachytene/Pachynema - synapsis is complete, chiasmata, crossing over
- Diplotene/Diplonema - DNA recombination is complete
- Diakinesis - shorter and thicker
• Metaphase I - bivalents migrate within a cell migrate to metaphase plate
• Anaphase I - move to opposite poles
• Telophase I - complete their migration to the two poles, nucleolus reappears
CYTOKINESIS
• Formation of cleavage furrow, two daughter cells are produced, each with one half of he
number of chromosomes of the original parent cell
MEIOSIS II
• Prophase II - composed of a pair of sister chromatids attached by a common centromere.
• Metaphase II - Centromeres are positioned at the equatorial plane.
• Anaphase II - Centromeres divide and the sister chromatids of each dyad are pulled to opposite
poles
• Telophase II - One member of each pair of homologous chromosome present in each pole

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