Gajwani 2013
Gajwani 2013
Practitioner points
The treatment of affective dysregulation has implications on social integration, crucial to the recovery
of young people in the emerging psychosis.
Assessment of adult attachment difficulties may bring to the forefront specific negative internal
working models (and interpersonal schemas) which may indicate vulnerability to social anxiety and
depression.
Young adults at ultra-high risk of psychosis with emotional difficulties may be better at help seeking and
therefore over-represented in this sample.
Cross-sectional data analysis makes it difficult to draw aetiological links between adult attachment and
affective dysregulation.
*Correspondence should be addressed to Dr Ruchika Gajwani, School of Psychology, University of Birmingham, Edgbaston,
Birmingham B15 2TT, UK (email: [email protected]).
DOI:10.1111/bjc.12027
Attachment, affective dysregulation and psychosis 425
1
Secure attachment style represents positive self and other cognitions with low attachment avoidance and anxiety/dependence.
Preoccupied and fearful attachment styles represent elevated dependency and a negative model-model-of-self; but differ in their
model-of-other. Fearful have high avoidance and a negative world view, whereas preoccupied are dependent and have a positive
world view. Dismissive attachment style avoid intimacy, have a positive self-worth and a negative world view.
426 Ruchika Gajwani et al.
regulation difficulties (Owens, Haddock, & Berry, 2012), dissatisfaction with quality of life
(Couture, Lecomte, & Leclerc, 2007) and negative schizotypal feature of social anhedonia
(Berry, Wearden, Barrowclough, & Liversidge, 2006). Also, embedded in attachment
theory is its association with emotional functioning (Bowlby, 1982), which provides a
developmental framework for affective dysregulation in psychosis (Berry, Barrowclough,
& Wearden, 2007). The evidence supporting the association between insecure attach-
ment and affective disorders is well documented (Bowlby, 1973, 1980; Cummings &
Cicchetti, 1990; Roberts, Gotlib, & Kassel, 1996), and therefore crucial for this research as
affective dysregulation in the emerging psychosis is a vital predictive factor for transition
to psychosis (Johnstone, Ebmeier, Miller, Owens, & Lawrie, 2005; Owens, Miller, Lawrie,
& Johnstone, 2005; Yung et al., 2003).
Childhood traumatic experiences and anomalous attachment may increase vulnera-
bility to negative interpersonal schemas, which in turn may partly account for
psychotic-like experiences (Fisher, Appiah-Kusi, & Grant, 2012), emotional response to
psychosis (Birchwood, 2003; Birchwood et al., 2004; Read & Gumley, 2008), and
recovery after psychosis (Gumley & MacBeth, 2006). Predictions from attachment to
psychopathology get more complex as attachment styles are more durable in low-risk
samples and more variable in high-risk samples (Van IJzendoorn & Bakermans-Kranen-
burg, 1997) and in this respect the association between attachment and the emerging
psychosis should be deliberated under the larger framework of developmental risk and
protective factors (Sroufe, Carlson, Levy, & Egeland, 1999).
The study endeavours to describe the composition of attachment styles in the
ultra-high-risk (UHR) sample, and contrast these with the standardized scores from
normative data. We hypothesized that (1) individuals at UHR of psychosis with an insecure
attachment style (preoccupied, dissociated, and fearful) will report significantly higher
levels of depression, state anxiety, and social anxiety, compared to UHR individuals with a
secure attachment style, and (2) social anxiety would mediate the relationship between
attachment styles and depression in the UHR sample, based on previous findings by Eng,
Heimberg, Hart, Schneier, and Liebowitz (2001).
Method
Sample
Fifty-one participants meeting the UHR criteria for developing psychosis (McGlashan
et al., 2002), between 16 and 35 years, were recruited from a youth mental health service
based within an Early Intervention Team for psychosis in the United Kingdom. Any
participant that had made transition to psychosis or did not meet UHR criteria at the time
of screening assessment was excluded from the study. The sample comprised 33 males
and 18 females, with a mean age of 19 (SD = 3.09, minimum = 16, maximum = 30). The
ethnic breakdown of the sample was 57% White British, 31% Asian, 4% Black/Black British
Caribbean, 2% Black/Black British African and 6% were of Other ethnic background. The
majority of the sample (51%) was in education at the time of assessment and 65% of the
sample had a General Certificate of Secondary Education (GCSE) as a minimum
educational qualification.
Design
Clients meeting UHR criteria were contacted individually to arrange appointments at their
GP surgery, community mental health service or at their accommodation, depending on
Attachment, affective dysregulation and psychosis 427
their suitability and risk assessment. Clients meeting the screening criteria for UHR of
psychosis were offered clinical intervention and voluntary participation in research
conducted by the team. Consented clients completed a baseline assessment pack which
included measures outlined below within 2 weeks of acceptance to the youth mental
health team, prior to any therapeutic intervention.
Assessments
Ultra-high risk of psychosis
To assess intake criteria for prodromal symptoms of psychosis, referrals were assessed
using the Structured Interview for Prodromal Syndromes (SIPS)2 (McGlashan et al., 2002).
The SIPS is a structured diagnostic interview consisting of four measures: (1) Scale of
Prodromal Symptoms (SOPS), a 19-item scale assessing positive, negative, disorganization,
and general prodromal symptoms, (2) DSM-IV schizotypal personality disorder checklist,
(3) questionnaire for family history of mental illness, and (4) Global Assessment of
Functioning scale. The criteria for prodromal syndrome evaluated using the above
measures are given in the following: (1) brief intermittent psychotic symptom syndrome,
(2) attenuated positive symptom syndrome, and (3) genetic risk and deterioration
syndrome. The diagnostic interview has shown excellent inter-rater reliability and
predictive validity (Miller et al., 2002).
Adult attachment
The Revised Adult Attachment Scale (RAAS; Collins, 1996) is a modified version of the
Adult Attachment Scale (Collins & Read, 1990) and is used to establish attachment styles in
adulthood. The RAAS is an 18-item self-report questionnaire with three subscales (each
composed of six items): (1) comfort with closeness, (2) comfort depending on others, and
(3) anxiety in relationships. Each response is rated on a 5-point scale (1 = not at all
characteristic of me to 5 = very characteristic of me). A higher score on the subscales
represents greater comfort with closeness, greater confidence in dependability of others
and higher anxiety associated with relationships. On the basis of the three RAAS subscales,
adult attachment can be assessed using a continuous measure (extent of comfort with
closeness, comfort depending on others, and fear of rejection) or can be categorized into
Bartholomew’s (1990) four attachment styles (secure, preoccupied, fearful, and
dismissing). The RAAS has good reliability for the three attachment dimensions of Close,
Depend and Anxiety (a = .77, .78, and .85, respectively) and its validity is reaffirmed by its
strong correlation (r = .98) with the original Adult Attachment Scale (Collins & Read,
1990). Within psychosis, the scale has demonstrated excellent internal consistency;
Closeness a = .86, Dependence a = .86, and Anxiety a = .97 (Tait, Birchwood, &
Trower, 2004). Tait et al. (2004) also showed moderate correlations (significant)
between the Parental Bonding Instrument (Parker et al., 1997) and the RAAS.
Anxiety
The Beck Anxiety Inventory (BAI; Beck, Epstein, Brown, & Steer, 1988) is a 21-item
self-report inventory, with each response rated on a 4-point scale ranging from 0 (not at
2
Prior to screening and recruitment of UHR participants, the primary researcher (RG) underwent training to adequate levels of
reliability on the Structured Interview for Prodromal Syndrome.
428 Ruchika Gajwani et al.
all) to 3 (severe-it bothered me a lot), based on symptoms of anxiety in the previous week.
It is a widely used measure of anxiety among psychiatric samples, with a high internal
consistency (a = .92) and good test–retest reliability (r = .75). BAI also has good
concurrent validity as it correlates well with other anxiety measures (Beck et al., 1988).
Social anxiety
The Social Interaction Anxiety Scale (SIAS) and Social Phobia Scale (SPS) were both
developed by Mattick and Clarke (1998) as companion measures to assess social anxiety.
Social Interaction Anxiety Scale. The SIAS (Mattick & Clarke, 1998) is a 20-item
self-report measure, assessing general social interaction anxiety. The SIAS assesses fear of
general social anxiety through the items describing apprehension in different group
interactions, such as difficulty talking to someone of the opposite sex, worries about
expressing one’s feelings, or nervousness mixing with people one doesn’t know well.
Total scores range from 0 to 80 with a higher score indicative of greater social interaction
anxiety. With a cut-off score of 36, SIAS has demonstrated discriminate validity is assessing
social anxiety compared to other anxiety disorders, with a sensitivity of 0.93, specificity of
0.66 and a positive predictive value of 0.84 (Peters, 2000).
Social Phobia Scale. The SPS (Mattick & Clarke, 1998) is a 20-item self-report measure,
assessing performance related anxiety and a fear of scrutiny. The SPS measures fear of
scrutiny with the items describing different performance-related anxieties, such as
uneasiness eating, drinking, writing, using public toilets, travelling on public transport, or
being looked at. With a cut off score of 26, SPS has shown high levels of internal
consistency (a = .89–.94) and test-retest reliability (r = .93) (Mattick & Clarke, 1998;
Peters, 2000).
Depression
The Beck Depression Inventory (BDI; Beck, Rush, Shaw, & Emery, 1979) is a 21-item
self-report measure used to assess depression severity in the previous week including the
day of assessment. It is a widely used measure for depression prevalence and intensity in
different psychiatric and non-psychiatric samples. The BDI has demonstrated good
concurrent validity, shown in high mean correlations with other measures of depression
and has good discriminant validity, reliably differentiating depressed from the
non-depressed individuals (Richter, Werner, Heerlein, Kraus, & Sauer, 1998).
Statistical analysis
Analyses for this study were performed using SPSS v.18 (SPSS Inc., Chicago, IL, USA) for
Windows. The normality of distribution of all measures was assessed using the
Kolmogorov–Smirnov test. Descriptive analysis and ANOVA were used for preliminary
analysis of the data and to investigate the association between attachment styles with
depression, anxiety, and social anxiety. To test the mediating relationship between
attachment styles (i.e., predictor variable) and depression with social anxiety as the
mediating variable, multiple regression analysis was conducted.
Attachment, affective dysregulation and psychosis 429
Results
Forty-five participants met UHR criteria for attenuated positive symptom syndrome, four
for genetic risk and deterioration syndrome, and two for brief intermittent psychotic
symptom syndrome. Seventy-eight per cent of the sample reported moderate to severe
levels of depression (mean = 28.50, SD = 12.34) at intake baseline, 59% reported
moderate to severe levels of anxiety state (mean = 22.65, SD = 12.83), 65% met the cut
off for social interaction anxiety (mean = 39.29, SD = 17.17), and 74% reported social
performance anxiety (mean = 33.87, SD = 15.44). Mean scores (SD) on RAAS for the
Close, Depend, and Anxiety subscales were 17.93 (5.54), 16.05 (4.87), and 19.58 (6.42)
respectively. The distribution of the four attachment styles in the UHR sample were
compared to published findings in a community sample of young adults. Eighty per cent of
the UHR sample were insecurely attached [i.e., fearful (43%), preoccupied (20%),
dismissive (17%)] in comparison to 37% reported in the community sample by Stein et al.
(2002). There were no age and gender differences in attachment styles.
Table 1. ANOVAs and post-hoc comparisons with attachment styles as the grouping variable and
depression and social anxiety symptoms as dependent variables
Social anxiety
SIAS 23.00 (16.24) 42.10 (12.88) 31.56 (17.12) 48.59 (12.65) Secure < preoccupied*,
fearful***
SPS 20.75 (11.85) 35.89 (14.16) 25.00 (16.58) 41.38 (12.21) Fearful > secure**,
dismissive*
Depression
BDI 15.70 (9.20) 38.56 (8.71) 24.89 (9.60) 31.68 (10.83) Secure < preoccupied***,
fearful***
Anxiety
BAI 17.50 (10.31) 33.00 (12.31) 15.33 (10.36) 23.27 (12.40) Preoccupied > secure*,
dismissive*
Note. SIAS = Social Interaction Anxiety Scale; SPS = Social Phobia Scale; BDI = Beck Depression
Inventory; BAI = Beck Anxiety Inventory. *p < .05; **p < .01; ***p < .001.
430 Ruchika Gajwani et al.
attachment style rated themselves with significantly lower social performance anxiety
than those with fearful attachment style. State anxiety was significantly lower in secure
and dismissive attachment styles than those with preoccupied attachment style.
Table 2. Regression analysis with attachment style as a predictor variable and social anxiety or
depression as the outcome variable
Discussion
Results on adult attachment dysfunction showed that 80% of young adults at UHR of
psychosis in this study (N = 51) were insecurely attached, of which 43% (n = 22)
presented with fearful attachment, 20% (n = 10) preoccupied attachment and 17% (n = 9)
dismissive attachment. The findings suggest that the UHR sample predominantly expressed
anxiety about relationships, such as fears of rejection and being unloved. Young people at
UHR of psychosis reported greater discomfort with intimacy and dependence on others, as
well as fears of abandonment in comparison with the undergraduate samples on which the
Adult Attachment Scale was developed (Collins, 1996). In another study of a community
sample of young adults (Stein et al., 2002), 63% of their sample was securely attached,
which reflects a striking contrast to young people presenting to an early intervention
service for high risk of psychosis. The attachment profiles of the UHR sample in this study
are comparable to a depressed group (BDI ≥ 16) of respondents (Murphy & Bates, 1997;
Reinecke & Rogers, 2001). This is reflected in predominantly fearful and preoccupied
attachment styles in this study’s UHR group. While both these styles are characterized by an
elevated desire for dependency (Bartholomew, 1990), individuals with a preoccupied
attachment style rely on others’ opinion to maintain self-worth (i.e., positive internal
working model of other and a negative internal working of self), whereas individuals with
fearful attachment avoid intimacy with others and have a negative internal working model
of self and other. Overall, these findings suggest that the young people at UHR of psychosis
in this sample may resemble an affectively disturbed group (Morrison et al., 2012; Wigman
et al., 2012). These findings have clinical implications for screening, therapeutic alliance
and intervention, as the focus may as much have to be on the affective dysregulation, as on
positive symptoms of psychosis in the high-risk group.
The findings showed that adult attachment was significantly associated with
depression, anxiety, and social anxiety, with insecurely attached participants reporting
elevated scores on all three affective dimensions. More specifically, participants with
fearful and preoccupied attachment styles had greater social interaction anxiety and
depression than those with secure attachment styles, and those with fearful attachment
also had higher scores on social phobia. Bartholomew’s (1990) four-category model of
adult attachment demonstrates that individuals with a preoccupied attachment style have
a negative view-of-self but a positive view-of-other and those with fearful attachment have
a negative view of self and other. The results of the association between adult attachment
dysfunction and affective dysregulation in the UHR sample suggest that a negative
self-schema, regardless of a view of others is associated with a significant apprehension of
group interaction and vulnerability to depression. However, those who have a negative
view of self and other (i.e., fearful attachment) are likely to experience greater depression,
social anxiety, and social phobia than someone with a secure attachment style.
Our findings are also in line with those of previous studies (Lee & Hankin, 2009) in
which an association between depression and anxious attachment has consistently been
432 Ruchika Gajwani et al.
reported. In two separate studies (Carnelley, Pietromonaco, & Jaffe, 1994; Murphy & Bates,
1997), depression was significantly associated with preoccupied and fearful attachment,
which suggests that depressed mood is linked to a negative view of self, irrespective of a
positive or negative view of others. Support for the association between social anxiety and
insecure attachment has been reported in a longitudinal study of young children who were
followed from the age of 15 months to 9 years (Bohlin, Hagekull, & Rydell, 2000). Their
study revealed that securely attached infants had better social functioning at school and less
social anxiety than children who had been insecurely attached.
The results of this study are consistent with evidence for insecure attachment
relationships as predictors of anxiety symptoms and related affective disorders. In a
longitudinal study, Warren, Huston, Egeland, and Sroufe (1997) found that young children
with anxious/resistant attachment were more likely to develop anxiety disorders in
adolescence than those who were securely attached. These findings were significant after
accounting for the effect of maternal anxiety and temperament assessed when the
children were newborns. There is also evidence from a cross-sectional analysis in a sample
of young adolescents (N = 155), for a significant association between insecure attach-
ment and elevated anxiety symptoms (Muris, Meesters, van Melick, & Zwambag, 2001).
Overall, the results are consistent with previous work which suggests that difficulties in
interpersonal relationships are associated with less favourable emotional regulation
(Mikulincer et al., 2003).
The link between attachment difficulties and affective disturbances of depression and
anxiety is fairly well established (Dozier, Stovall, & Albus, 1999; Rosenstein & Horowitz,
1996), the focus on adult attachment and social anxiety has been limited, despite its clinical
implications as a disorder and a psychiatric comorbidity. With the aim of examining the
association between adult attachment, social anxiety and depression, Eng et al. (2001)
found, among patients with social anxiety disorder, two clusters of attachment styles:
patients with anxious attachment style experienced greater social anxiety and avoidance,
depression and fear of scrutiny than the securely attached patients, as well as a non-clinical
control group. Of further interest is the reported mediational role of social anxiety
symptoms in the association between attachment styles and depression. To explain these
results, the authors draw on the cognitive and affective influences of attachment
relationships (Collins & Read, 1990) which may increase the severity of social anxiety, and
this in turn may affect the experience of depression. Based on the findings of Eng et al.
(2001) and results of the ANOVA, a similar mediational analysis was performed. Due to the
cross-sectional nature of the data, it is difficult to establish the predictive capacity of the
variables; however, social anxiety and social phobia were kept as a mediating factors for
depression in the analyses based on the assumption that social anxiety is a risk factor for
subsequent depression (Stein et al., 2001). Results of the analysis in the UHR sample failed
to support the mediating role of social anxiety between attachment styles and depression.
However, of interest was the mediating role of social phobia between attachment and
depression. With regard to performance related anxiety, it is known that self-criticism and
fear of scrutiny are not unique to social phobia (Birchwood et al., 2007). Social functioning
impairments are predictors of transition to psychosis but may also determine vulnerability
to other affective and non-affective disorders in young people at risk of psychosis.
While it may be difficult to clinically differentiate depression and anxiety (Shorter &
Tyrer, 2003), and to study the causal links due to cross-sectional analysis, results suggest
that depression mediated the relationship between adult attachment and social anxiety in
the UHR sample. The negative schemas emerging from an adult attachment dysfunction
may increase the vulnerability to depression (Murphy & Bates, 1997), in turn reducing the
Attachment, affective dysregulation and psychosis 433
Methodological considerations
The high prevalence of affective dysregulation in the UHR sample may be due to a
self-selection/referral bias, with better detection of young adults expressing distress. It
may also be that high-risk young adults with emotional difficulties may be better at help
seeking and therefore over-represented in this sample. The use of a single index measure
of adult attachment may bias the findings as affective dysregulation could contribute to the
current working models of attachment. Also, RAAS has been validated in adult samples
and while it has shown significant correlations with a childhood attachment questionnaire
in an adult sample with psychosis (Tait et al., 2004), the study considers the use of an adult
attachment measure on a proportion of clients under 18 years of age (33%) in this study, a
methodological limitation. Although the cross-sectional nature of the data makes it
difficult to provide sufficient evidence for the causal links between adult attachment styles
and affective dysregulation, our findings are closely in line with longitudinal findings on
developmental psychopathology.
Clinical implications
Taking into account the methodological strengths and weaknesses, findings of this study
have clinical and theoretical implications for understanding developmental pathways to
affective dysregulation, specifically social anxiety and depression in young people at UHR
of developing psychosis. Our findings are vital in bringing to the forefront clinically
significant levels of distress and anxiety experienced by the young people at UHR of
psychosis. The influence of adult attachment difficulties on vulnerability to experiences of
depression and social anxiety may indicate overriding interpersonal negative schemas,
specific to attachment styles. The treatment of affective dysregulation and implications on
social integration is crucial for recovery for young people in the emerging psychosis, as the
established affective bonds reflect the internal models of self and other, and their specific
association with emotional regulation.
Acknowledgements
The authors would like to thank the Early Detection and Intervention Team at Birmingham and
Solihull Mental Health Foundation Trust for their support and help with recruitment. Professor
434 Ruchika Gajwani et al.
Birchwood and Dr Patterson are partly funded by the National Institute for Health Research
(NIHR) through the Collaborations for Leadership in Applied Health Research and Care for
Birmingham and Black Country (CLAHRC-BBC) programme.
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