Monohybrid and dihybrid cross

Problem 1:
A brown eyed man marries a blue eyed woman and they have eight children, all brown eyed. What are the
genotypes of all the individuals in the family?

Problem 2:
A blue eyed man, whose both parents were brown eyed, marries a brown-eyed woman. They had one child,
who is blue eyed. What are the genotypes of all the individuals in the problem mentioned above?

Problem 3:
What are the chances that the first child of a marriage of two heterozygous brown eyed parents will be blue
eyed? If the first child is brown eyed what are the chances that the second child would be blue eyed?

Problem 4:
Albinism is recessive to normal body pigmentation in man. It is an autosomal trait. If a homozygous normal man
marries an albino girl, what would be the phenotypic and genotypic ratios in F1 generation from this marriage?

Problem 5:
Albinism, the total lack of pigment is due to a recessive gene. A man and woman plan to marry and wish to
know the probability of their having an albino child. What advice would you give to them if ?
(a) Both are normally pigmented, but each has one albino parent.
(b) The man is an albino.
(c) The man is an albino and the woman's family includes no albino for at least three generations.

Problem 6
Hearing (D) in dogs is dominant. Deafness (d) in puppies is caused by a recessive gene. Deaf puppies have the
genotype dd. You do the test cross with deaf dog and hearing dog, and you get 50% hearing and 50% deaf
puppies, what was the genotype of parent dogs?

Problem 7:
In man brown eyes (B) are dominant to blue (b) and dark hair (R) are dominant to red hair (r). A man with brown
eyes and red hair marries a woman with blue eyes and dark hair. They have two children, of whom one has
brown eyes and red hair. Give the genotypes of the parents and children.

Problem 8
When round and yellow seeded pea plants (YYRR) are crossed with green and wrinkled (yyrr) seeded pea
plants the F1 are yellow and round seeded plants (YyRr).
What will be the results when this F1 is crossed with green and wrinkled seeded (yyrr) parents?

Problem 9
In horses, the colour black is due to a dominant allele (B) and chestnut colour is due to the recessive allele (b).
The trotting gait is due to a dominant allele (T) and the pacing gait to the recessive (t). What will be the
gametes produced by a homozygous black pacer?

Problem 10
Seeds of pea plants can be round (dominant trait - R) or wrinkled (recessive - r). They also can be yellow (Y) or
green (y).
The pea plant with wrinkled and yellow seeds is crossed with the pea plant with round and green seeds. In F1
generation, you have plants with yellow round seeds and plants with wrinkled yellow seeds in ratio 1: 1.
What are the genotypes of P and F1generations?
SEX-LINKED INHERITANCE

Problem 1:
Of what type will be the children with reference to colour blindness, when a man is colour-blind and
his wife is normal?

Problem 2:
When a haemophilic male is married to a heterozygous carrier female, what haemophilic proportion
will be present in children of each sex?

Problem 3:
When a haemophilic male is married to a homozygous non-haemophilic female what will be the
result of this marriage?

Problem 4:
Of what type will be the children with reference to colour blindness, when a woman is colour-blind
and her husband is normal?

Problem 5:
A woman has normal vision but her father was colour-blind. She marries a man who is colour blind.
Find out the probability of the first child being colour blind if it is (a) Son or (b) Daughter

Problem 8
If a couple's first child is a boy, what is the probability that their next child will be a girl? And why?
BLOOD TYPE

Problem 1
A man with A blood type married to a woman with AB blood type. They have a daughter with blood
type B. What blood type can their son have?

Problem 2
A married couple has four children with four different blood types. Find possible genotype of parents
and children.

Problem 3
A woman with type A blood is claiming that a man with type AB blood is the father of her child who
is type B.
Show ALL the possible crosses; remember that the woman can have AA or AO genotypes.

Problem 4
A man with type AB blood is married to a woman with type O blood.
They have two natural children and one adopted child. Jane has type A blood, Jordan has type B
blood, Marlin has type O blood.
Which child was adopted? How do you know?

Problem 5
A woman is searching for her father and she has type O blood. She looks through records of men
who could be her father. Which blood type can she eliminate from her search? (In other words, her
dad CANNOT be what blood type.)
Explain how you know this.
INTERACTIONS OF ALLELES OF ONE GENE

1. Chickens have short or long legs. We get 10,000 eggs from the crossing between a rooster
and a hen, both with short legs. Only 7498 chickens hatched, 2483 of them have long legs,
others - short legs. Find the genotypes of all F1 Organisms (including those, which didn’t
hatch)
2. What are the expected offspring of two Snapdragon plants with pink flowers?
№1
One organism has this genotype:
AaBBCcdd
Write all types of gametes produced by this organism. (Write alleles of all possible gametes)

№2
In certain plants, tall is dominant to short. If a heterozygous plant is crossed with a homozygous tall
plant, what is the probability that the offspring will be short? Show the genotypes of parents.

№3
Following a SsYy x SsYy cross, what fraction of the offspring are predicted to have a genotype
that is heterozygous for both characteristics? Write your solution.

№4
Given the genotypes of parents: AABBCc x AabbCc.
Find the probability of individuals which have the same phenotype with the first parent?
Show your solution.

№5
In humans, red-green colour-blindness is inherited as a sex-linked recessive. If a colour-blind woman
marries a man who has normal vision, what would be the expected genotypes and phenotypes of all
possible children?

№6
In humans, haemophilia is inherited as a sex-linked recessive. Coloured figures show individuals with
this disorder, white figures are normal or carriers. There is a family tree here:

Write the genotypes of all shown family members.

№7
The rabbit of agouti colour is crossed with a chinchilla rabbit. In the next generation, we get two
agouti and one white rabbit.
What type of offspring can two parental rabbits potentially have? (Write the genotypes and
phenotypes of all family members)
№8
What are the blood types of possible offspring of a cross between individuals that are type AB and
type 0? (Write the genotypes and phenotypes of all family members)

№9
In the maternity hospital, four babies were born in one night, and they all had different blood types:
A, B, AB, and 0.
There were four pairs of parents with following blood types:
I) 0 and 0;
II) AB and 0;
III) A and B;
IV) B and B.
Determine the parents and their children. Show your solution.

№10
One organism has three heterozygous genes on one pair of homologous chromosomes: DdRrTt.

a) Write all possible types of gametes (shows all possible sets of alleles in gametes).
b) What types of gametes will be more than others.
c) What are genes that are on the same chromosome called?
 Name: _____________________________________________ Period: _______

Multiple Allele Traits in Rabbits (Bio 2A)

Allele Phenotype

C Rabbit with full color

(black or brown)

ch
c
Rabbit with light gray
coat

A brown rabbit can have the following

Himalayan (white with genotypes:
h
c dark ear tips, nose,
paws, and tail) ch h
CC CC Cc

*Fun fact: the “ch” stands

c Albino (white) for “chinchilla” which is a
gray coloration in rabbits
and chinchillas!

ch h
Order of dominance C→C →c →c

1. The chart shows four alleles that affect the coat color of rabbits. Each allele is dominant
to the ones below it. For each genotype, indicate the color of rabbit:

ch
CC
h
CC

cc
ch
C c
h
C c
 ch h
C C
2. Show the cross between an albino rabbit (cc) and a black rabbit (CC)

What are the phenotypes of the

offspring and in what proportion?

ch h
3. Show the cross between two gray rabbits that are both C C .

What are the phenotypes of the

offspring and in what proportion?

4. Show the cross between a gray rabbit and a black rabbit, if BOTH parents also have an
albino (c) allele.

What are the phenotypes of the

offspring and in what proportion?

5. Show the cross of a gray rabbit that carries the albino allele with a black rabbit that
carries the gray allele.

What are the phenotypes of the

offspring and in what proportion?
 Name _____________________________________________

Genetics: Blood Types

Blood Type is controlled by 3 alleles: A, B, O. A & B are codominant, O is recessive.

1. a) What are the two genotypes possible for a person who has A blood? _________
b) What genotype does a person with AB blood have? ________
c) What genotype does a person with O blood have? _________
d) What are the two genotypes possible for a person who has B blood? ________

2. A man with type AB blood is married to a woman also with type AB blood.

What proportion of their children will have: Show the cross:

A blood? _______

B blood? ______

O blood _____

AB blood ______

3. A man with type B blood (genotype BB) is married to a woman with type O blood. Show the
cross:

What proportion of their children will have:

A blood? _______

B blood? ______

O blood _____

AB blood ______

4. A woman with type A blood (genotype AO) is married to a type B person (genotype BO). Show
the cross

What proportion of their children will have:

A blood? _______

B blood? ______

O blood _____

AB blood ______
5. A woman with type A blood is claiming that a man with type AB
blood is the father of her child who is type B.

Show ALL the possible crosses; remember that the woman can have AA
or AO genotypes.

Could this man be the father of the child? ____________

Assuming that he is the father, what must the mother’s genotype be? _____

6. A man with type AB blood is married to a woman with type O blood.

They have two natural children and one adopted child.

Jane has type A blood, Jordan has type B blood, and Marlin has type O
blood.

Which child was adopted? ____________________

How do you know?