2nd-Year-Endocrine System Study Guide
2nd-Year-Endocrine System Study Guide
ENDOCRINE SYSTEM
AFFECTIVE .........................................................................................................................................................................................................................
Introduction to the Course/Module .....................................................................................................................................................................................
GUIDE
Teaching and learning strategies: .........................................................................................................................................................................................
Learning opportunities..........................................................................................................................................................................................................
Time
tables:...........................................................................................................................................................................................................................
This Study guide of the module/course outlines the
Assessment tools: .................................................................................................................................................................................................................
key components and areas for the facilitation of the
students.
Internal Evaluation:...............................................................................................................................................................................................................
Attendance Requirement: ....................................................................................................................................................................................................
Department of Medical Education
Vision and Mission of KGMC
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Curriculum Committee KGMC
Chair:
Professor Dr.Zahid Aman, Dean KGMC.
Co-Chair:
Dr. Sabina Aziz, Associate Dean KGMC.
Clinical Sciences:
Dr. Mohammad Noor Wazir, Department of Medicine KGMC/HMC
Dr. Bushra Rauf Department of Gynae KGMC/HMC.
Dr. Sofia Iqbal, Department of Ophthalmology KGMC/HMC.
Dr. Said Amin Department of Medicine KGMC/HMC.
Dr. Ghareeb Nawaz Department of ENT KGMC/HMC.
Dr. Jamshed Alam Department of Surgery KGMC/HMC.
Dr. Ambreen Ahmad, Department of Pediatrics KGMC/HMC.
Dr. Ain-ul-Hadi Department of Surgery KGMC/HMC.
Dr. Fawad Rahim Department of Medicine KGMC/HMC.
Behavioral Sciences:
Dr. Ameer Abbas Department of Psychiatry KGMC/HMC.
Medical Education
Dr. Naheed Mahsood, Department of Medical Education, KGMC.
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Dr. Naveed Afzal Khan, Department of Medical Education, KGMC.
Dr. Khurram Naushad, Department of Medical Education, KGMC.
Basic Sciences:
Dr. Amin-ul-Haq Department of Biochemistry, KGMC.
Dr. Khalid Javed Department of Pathology, KGMC.
Dr. Raheela Amin Department of Community Medicine, KGMC.
Dr. Zubia Shah Department of Physiology, KGMC.
Dr. Naheed Siddique Department of Forensic Medicine, KGMC.
Dr. Shams Suleman Department of Pharmacology, KGMC.
Dr. Shahab-ud-Din, Department of Anatomy, KGMC.
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Module Committee for Endocrinology
Endocrine System
1. Dr. Sarah Shahid Lecturer Department of Physiology……………... Module Coordinator
2. Dr. Naheed Mahsood Assistant Professor DME .................................Module Secretory:
3. Dr. Naveed Afzal Khan Coordinator DME ......................................Module Secretory
4. Dr. Khurram Naushad DME ………………………………………..………. Module Coordinator.
5. Dr. Shabnam Gul Associate Admin…………………………….………Member:
6. Dr. Shakeela Asif Associate Professor Department of Community Medicine…Member
7. Dr. Muhammad Hussain Afridi Assistant Professor Department of Endocrinology…Member
8. Dr. Saima Nadeem Assistant Professor Department of Pathology…………………… Member
9. Dr. Ameer Abbas Assistant Professor Department of Behavioral Sciences…Member
10. Dr. Yousaf Jan Assistant Professor Department of Surgical B ….Member
11. Dr. Afsheen Mehmood Assistant Professor Department of Physiology…….........Member
12. Dr. Gulnaz begun Senior Lecturer Department of Biochemistry……………. Member
13. Dr. Fahad Falah Lecturer Department of Pharmacology……………………..Member
14. Dr. Faiza Nadeem Lecturer Department of Forensic Medicine……………….Member
15. Dr. Qaisar Zaman, Lecturer Anatomy. .............................................................Member:
16. Dr. Farida Ahmad Lecturer Physiology…………………………………………..Member
17. Miss. Fayal Alam Student of Final Year…………………………………………Member
18. Miss. Faiza Gul Student of Final Year……………………………………………Member
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Integrated curriculum:
An integrated curriculum is all about making connections, whether to real life or across the disciplines, about skills or about knowledge.
An integrated curriculum fuses subject areas, experiences, and real-life knowledge together to make a more fulfilling and tangible
learning environment for students. Integrated teaching means that subjects are presented as a meaningful whole. Students will be
able to have better understanding of basic sciences when they repeatedly learn in relation to clinical examples. Case based
discussions, computer-based assignments, early exposure to clinics, wards, and skills acquisition in skills lab are characteristics of
1. Knowledgeable
Knowledgeable about the diseases and health conditions prevalent in the population of Pakistan and use Evidence-based medicine to
2. Skillful
Skillful in History taking and Physical examination to compassionately deal with a patient.
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3. Community health promoter
Take appropriate decisions and actions for protecting and promoting the health of their community.
4. Critical Thinker
Evaluate critically the patient data to effectively deal with complexity of medical decisions for the best possible outcomes using
5. Professional
Display professional values (honesty, accountability, cultural and religious sensitivity), attitudes and behaviors (empathy, ethics, good
communication skills and lifelong learner) that embody good medical practice.
6. Researcher
Exhibit a spirit of inquisitiveness, inventiveness, and ethical conduct while carrying out research in accordance with the prescribed
guidelines.
Demonstrate exemplary conduct and leadership in Advancing healthcare, enhancing medical education, and Enhancing the trust of the
1. Acquire a high level of clinical proficiency in history taking, physical examination, differential diagnosis, and the effective use of med-
icine’s evolving diagnostic and procedural capabilities including therapeutic and palliative modalities
PSYCHOMOTOR
By the end of five year MBBS program the KGMC student should be able to;
4. Perform BLS
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AFFECTIVE
By the end of five year MBBS program the KGMC student should be able to
3. Counsel and educate patients and their families to empower them to participate in their care and enable shared decision-making.
5. Demonstrate in clinical care an understanding of the impact of psychological, social, and economic factors on human health an d dis-
ease
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Introduction to endocrine system
The Endocrine System is composed of glands that secrete chemicals called hormones into the bloodstream for the
control of body functions. ... Substances released by the hypothalamus trigger the production and secretion of
hormones by the pituitary gland. The endocrine system uses chemical messages in the form of hormones- chemical
substances that are secreted by cells into extracellular fluids and regulate metabolic activity. Blood transfers hormones
to target sites. Target cells or target organs Target cells must have specific protein receptor in order to be affected by
the hormones.
Hormones of the endocrine system coordinate and control growth, metabolism, temperature regulation, the
stress response, reproduction, and many other functions.
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General Learning Outcomes of Course
Knowledge
Development, structure, hormones and regulation of pituitary gland, thyroid gland, parathyroid gland, endocrine pancreas, and ad-
renal glands
Describe the etiology, pathophysiology, relevant clinical features and common investigations of disorders of these glands
Describe the basic concepts and components of medical professionalism
Skills
Describe the steps of writing a research proposal
Detect glucose in urine
Detect glucose in blood
Perform and interpret Glucose
tolerance test
Identify the structure of pituitary gland
under microscope
Identify the structure of thyroid gland under microscope
Identify the structure of adrenal gland under microscope
Affective
Demonstrate compassion and care for patients while performing any examination
Demonstrate the team work while working in the hospital environment.
Show good communication skills while performing tasks.
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List of Themes …………………………………………….TOTAL WEEKS-4
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MBBS Year-2: Endocrine Module
Hormone
MBBS Year-2: Endocrine Module
of Posterior Pitui-
16 Describe formation and physiological LGF Mcq/Seq
functions of ADH
Biochemistry Hormones 17 Define hormones and differentiate LGF Mcq/Seq
between the terms- endocrine,
Introduction
paracrine & autocrine
18 Classify hormones on various basis LGF Mcq/Seq
19 Discuss the mechanisms of action of LGF Mcq/Seq
hormones
20 Define 2nd messengers and their roles LGF Mcq/Seq
Anterior Pitui- 21 Enumerate the hormones of anterior LGF Mcq/Seq
tary hormones pituitary gland
22 Describe the chemistry, secretion, LGF Mcq/Seq
mechanism of action, regulation and
metabolic effects of Growth hormone
with its related clinical disorders
Posterior Pitui- 23 Enumerate the hormones of the LGF Mcq/Seq
tary hormones posterior pituitary gland
MBBS Year-2: Endocrine Module
Pharmacology Antithyroid drugs 49 Describe the types and mechanism of LGF Mcq/Seq
action of Antithyroid drugs
Community Diabetes mellitus 50 Describe the epidemiology, risk factors LGF Mcq/Seq
medicine and prevention of Diabetes Mellitus
Theme-3 (Increased thirst and urination)
Histology Pancreas 51 Describe the histological features of LGF Mcq/Seq
pancreas and differentiate between
exocrine and endocrine parts of
pancreas
Physiology Mechanism of 52 Explain Mechanism of action of insulin LGF Mcq/Seq
action of insulin
&its control
53 Describe the Control of Insulin LGF Mcq/Seq
Secretion
Physiological Ef- 54 Describe the effects of insulin on LGF Mcq/Seq
fects of insulin on carbohydrates, proteins and Fats
carbohydrates, metabolism
protein, and Fats
Physiology of 55 Describe regulation of glucagon and its LGF Mcq/Seq
effects
Glucagon
MBBS Year-2: Endocrine Module
Somatostatins
Physiological ef- 57 Describe Effects of hyperglycaemia LGF Mcq/Seq
fects of Diabetes
/hypoglycaemia on body functions
58 Explain Insulin resistance LGF Mcq/Seq
Biochemistry Pancreas 59 Enumerate the hormones secreted by LGF Mcq/Seq
pancreas
60 Describe the chemistry, biosynthesis, LGF Mcq/Seq
secretion, mechanism of action,
regulation and metabolic effects of
Insulin & Glucagon with its related
clinical disorders
Pharmacology Antidiabetic drugs 61 Explain the mechanism of action of oral LGF Mcq/Seq
antidiabetic drugs
62 Explain the mechanism of action and LGF Mcq/Seq
complications of Insulin therapy
Medicine Diabetes Mellitus 63 Explain the short-term and long-term LGF Mcq/Seq
complications of Diabetes Mellitus
64 Describe the pathophysiology, clinical LGF Mcq/Seq
features and treatment of Diabetes
Mellitus
Theme-4 (Moon face)
Gross 65 Describe the gross anatomy and LGF Mcq/Seq
anatomy relations of adrenal glands on both
sides
Embryology Adrenal gland 66 Describe the development of adrenal LGF Mcq/Seq
gland
Histology 67 Describe the microscopic picture of LGF Mcq/Seq
adrenal gland and differentiate be-
tween the various histological zones of
adrenal gland
Physiology Physiologi- 68 Describe Types, Mechanisms and LGF Mcq/Seq
cal func- regulation of mineralocorticoids
tions of Al-
69 Describe the physiological Effects of LGF Mcq/Seq
Aldosterone (Renal, Circulatory and
others)
MBBS Year-2: Endocrine Module
Histology Pituitary glands 84 Identify the structure of pituitary gland practical Mcq/Seq
under microscope
The following teaching / learning methods are used to promote better understanding:
Interactive Lectures
Skills session
Self-Directed Study
Interactive lectures:
An interactive lecture is an easy way for instructors to intellectually engage and involve students as active participants in a lecture-
based class of any size. Interactive lectures are classes in which the instructor breaks the lecture at least once per class to have students
participate in an activity that lets them work directly with the material.
The instructor might begin the interactive segment with an engagement trigger that captures and maintains student attention.
Then the instructor incorporates an activity that allows students to apply what they have learned or give them a context for up-
As the instructor feels more comfortable using interactive techniques he or she might begin to call upon a blend of various inte r-
In small groups, students observe patients with signs and symptoms in hospital or clinical settings. This helps students to relate
The shy and less articulate are more able to contribute. Students learn from each other. Everyone gets more practice at express-
ing their ideas. A two way discussion is almost always more creative than individual thoughts. Social skills are practiced in a 'safe' envi-
ronment e.g. tolerance, cooperation. This format helps students to clarify concepts acquire skills or attitudes. Students exchange opin-
ions and apply knowledge gained from lectures, tutorials and self-study. The facilitator role is to ask probing questions, summarize, or
Skills relevant to respective module are observed and practiced where applicable in skills laboratory or Laboratories of various
departments.
Self-directed learning, which involves studying without direct supervision in a classroom/Library, is a valuable way to learn and
is quickly growing in popularity among parents and students. Students’ assume responsibilities of their own learning through individual
study, sharing and discussing with peers, seeking information from Learning Resource Centre, teachers and resource persons within
and outside the college. Students can utilize the time within the college scheduled hours of self-study.
Time tables:
The timetables for the module will be shared via Edmodo and the notice boards in advance.
Assessment tools:
Theoretical knowledge is tested by a written examination system constituted by multiple choice questions (MCQs). The assess-
ment of practical knowledge involves oral, spot, or objective structured practical examinations (OSPE).
Multiple choice questions (MCQs) are a form of assessment for which students are asked to select the best choice from a list of
answers.
MCQ consists of a stem and a set of options. The stem is usually the first part of the assessment that presents the question as a
problem to be solved; the question can be an incomplete statement which requires to be completed and can include a graph, a
picture or any other relevant information. The options are the possible answers that the student can choose from, with the cor-
rect answer called the key and the incorrect answers called distractors.
Correct answer carries one mark, and incorrect ‘zero mark’. There is NO negative marking.
Students mark their responses on specified computer-based sheet designed for the college.
The block exam will comprise of 120 MCQs and will be compiled according to the shared blueprint.
Short Essay Questions (SEQ)
Short answer questions generally ask for brief, text-based responses and may also be referred to as fill-in-the-blank;
or completion questions.
Variations of the short answer question may request a list of terms or rules in which the order is not important, or may requ ire a nu-
merical or formula response.
Easy to write.
Reduces possibility of guessing.
Can have a lengthy stem such as a paragraph. (Caution: You generally should not expect an exact answer character-by-
character.)
May be easy to score if the required answer is short.
Disadvantages of Short Answer Questions
All the students are assessed on the same content by the same examiner in the same allocated time.
A structured examination will have observed, unobserved, interactive and rest stations.
Unobserved will be static stations in which students will have to answer the questions related to the given pictures, models or
Rest station is a station where there is no task given, and in this time student can organize his/her thoughts.
The Block OSPE will be comprise of 18 examined station and 7 rest stations. The stations will be assigned according to the sh red
blueprint.
Internal Evaluation:
Internal evaluation is a process of quality review undertaken within an institution for its own ends. 10% marks of internal evaluation
Biochemistry
Apart from this resource learning, students can consult books available in library or recommended by the specialty experts.