Patil Medical

D. Y.Internal College, Kolhapur

AsSsessement
Second MBBS Ist
PATHOL0GY Examination, June 2023
Date: 20,06.2023
Time: Ipm- 4:00pm
Section A MCQS: 1X 20 marks
are arrested by addition of colchicine in the following mitotic
Q1. For karyotyping, the dividing cells phase:
B. Metaphase
A. Prophase
D. Telophase
C. Anaphase
Q2. Mechanism of mammalian apoptosis involves the most important role of the following protein:

B. BCL-2
A. Receptor for TNF
D. CED-9
C. TPS3

Q3. In atrophy, the cells are:

B. Shrunken cells
A. Dead cells
D. Reversibly Induced cell
C. Irreversibly injured cells

Q4. In Alzheimer's disease, cerebral plaques consist of:

A. ATTR protein B. Aß>M protein

D. Prion protein
C. Aß protein
Q5. Grave's disease is a type of:
A. Type Ireaction B. Type II Reaction
C. Type lII reaction D. Type IV Reaction

06. The essentialdifference between plasma and interstitial fluid compartment is:
A. Glucose is higher in the former B.Urea is higher in the former
C. Protein content is higher in the former D.Potassium is higher in the former
Q7. The most common cause of arterial thromboemboli is:
A.Cardiac thrombi B. Aortic aneurysm

C. Pulmonary veins D. Aortic atherosclerotic plaques

Q8 Hepar lobatum is seen in:
A. Primary syphilis B. Secondary syphilis
C. Tertiary syphilis D. Congenital syphilis
Q9. Main cytokines acting as mediators of inflammation are as under except:
A. Interleukin-I (IL-) B. Tumour necrosis factor a (TNF-a)
C. Nitric oxide (NO)
D. Interferon-y (IF-y)
 Q10. P. falciparum differs from other
plasmodia in following aspects excepl
A. Itdoes not have exocrythrocytic stage
B. It parasitises only juvenile red cells
C.It causes imalignant malaria parasite
D.One red cell may contain more than onc
Q11. The following form of ionising radiation
exposure is associated with highest risk of cancer:
A. a-rays
C.y-rays B.B-rays
D. X-rays
O12, Which of the following viral infection is not known to produce any human tumour?
A. Polyoma virus B. EBV
C. HSV D. HTLV

Q13. In starvation, first nutrient to be depleted in the body is:

A. Fat B.Carbohydrate

C. Protein D. Vitamins

Q14. Mutations affecting germ cells produce:

A. Cancers B. Inherited diseases

C. Congenital malformations D.Aneuploidy

Q15. In irondeficiency anaemia, TIBC is:

B. Normal
A. Low

D. Borderline
C. High
Q16. In warm antibo dy autoimmune haemolytic anemia antibody is commonly:

A. IgA B. IgG

C. IgM D. IgD

Q17. The pathognomonic abnormality in b-thalassaemia minor is:

A. Marked rise in HbA2 B. Marked rise in HbF

C. Marked unconjugated hyperbiliubinaemia D. Marked anaemia

Q18. Philadelphia chromoso me is characterised by:

A. (8;14) B. t(9;:22)

C. (22:9) D. t(14;8)

Q19. Basophils are increased in:

A. Bronchialasthma B.CML

C. Angioneurotic oedema D.Corticosteroid therapy

Q
20. Popcorn cell is seen in which type of Hodg kins Lymphoma
A. Classical HD
B. Nodular Sclerosis

C. Lymphocytic Depletion D. Lymphocytic predominance

 D. Y. Patil Medical College,
Kolhapur
Second MBBS Ist Internal Assessment Exam, June 2023
PATHOLOGY
Date: 20.06.2023
Time: 1pm- 4:00 pm
5X 10marks
Section BSAQs: Answer any 10 out of
Q1. Write a note on Fracture
healing.
Q2. Enumerate and describe Endogenous and exogenous pigments.
Q3. Discuss the pathogenesis and lab
diagnosis of HY.
Q4. Write a note on Type II
Hypersensitivity Reaction.
Q5. Discuss Pathogenesis and Fates
ofThrombosis.
Q6. Define shock and discuss etiopathogenesis of septic shock.
Q7. Write a note on Cysticercosis.
Q8. Describe the pathogenes is of obesity and its consequences.
09. Write a short note on Klinfelter's Syndrome.

Q10. Write a note on lab diagnosis of Chronic Myeloid Leukemia.

of Reed-Sternberg cell.
QT. Define and classify Hodgkin's Lymphomas and describe different Types
3X 10marks
Section CLAQs: Answer any 3 out of 4
Malignant tumour. (4) Enumerate carcinogens
Q1. Detine Neoplasia. (2) Difference between Benign and
and Add a note on chemicalcarcinogenesis. (4)
and weight loss since 2 months X-Ray Chest
Q2. 42-Year-old male presented with history of fever cough
shows cavitary lesion in right Apical Lobe?
a. What is your diagnosis and why? (2)
disease? (4)
b. Describe etiopathogenesis of this findings
C. Describe Gross and Microscopic of this condition? (4)

03. 58-Year-Old Pure Vegetarian Male Presented with pallor, Weakness, baldy tongue and numbness in
MCV- 110fl.
the finger, his Hb was 8 gm %and
why? (2)
a. What's is your diagnosis and this condition? (4)
of
b. What is the etiopathogenisis
findings in such cases? (4)
C. What are the laboratory
causes (3) and Discuss mechanism of Apoptosis. (5)
04.What is apoptosis (2) and mention the