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10 views3 pages

8Th Outline

Uploaded by

Zainab Rasheed
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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BS-CHEMISTRY 8th SEMESTER OUTLINE

ANALYTICAL CHEMISTRY

Course Title ANALYTICAL CHEMISTRY - I


Course Code CHEM-412-I
Credit Hours 3

Luminescence Spectrometry
Introduction, Origin of fluorescence and phosphorescence spectra, Jablonski diagram,
Activation, Deactivation, Fluorescence spectrum, Fluorescent and phosphorescent species,
Photoluminescence and structure, Factors affecting fluorescence and phosphorescence,
Fluorescence quenching, Quantum yield, Instrumentation for fluorescence measurements,
Sources, Wavelength selectors, Sampling, Detectors, Readout devices, Instrumentation for
phosphorescence measurements, Sampling, Recording procedure, Applications of
fluorescence and phosphorescence

Thermal Methods of Analysis


Introduction, Instrumentation, Sources of errors, Data interpretation, Factors affecting curve,
Applications of TGA, DTA and DSC

Course Title ANALYTICAL CHEMISTRY - II


Course Code CHEM-412-II
Credit Hours 3

Hyphenated Techniques
Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Mass
Spectrometry (LC-MS), MS-MS, LC-FTIR, LC-NMR, CE-MS, Inductively Coupled Plasma-
Mass Spectrometry

Course Title ANALYTICAL CHEMISTRY - III


Course Code CHEM-412-III
Credit Hours 3

Advanced Separation Techniques


Introduction: Classifications of chromatographic techniques, Chromatographic processes,
Rate and plate theories of chromatography, Van-Deemter equation and its significance in
evaluating column efficiency

Electrophoresis: Theory and principle of Capillary Electrophoresis (CE) and Gel


Electrophoresis, Mobility, Electro-osmotic flow, Two-dimensional electrophoresis, Extraction,
Fractionation and Purification of Macromolecules

Gas Liquid Chromatography: Principle, Sample preparation/derivatization, Separation


process, Instrumental aspects and its applications

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BS-CHEMISTRY 8th SEMESTER OUTLINE

HPLC: Principle, Sample preparation, Separation process, Instrumentation, Method


development and applications. Fast protein liquid chromatography, HPTLC, HILIC, Capillary
electro-chromatography (CEC), Any other

Solid Phase Extraction (SPE): Principles and fundamentals, Importance of sample


preparation, SPE as sample preparation tool; Load and elute conditions, Sorbent chemistries,
Sorbent packaging, Packed particle beds and disks, Sorbent capacity and recovery, Offline and
online approaches, Method developments and protocols, Silica, Polymer and other sorbents,
Applications and automation, Application to real sample, i.e. Blood, General composition of
blood, Function of blood, Blood plasma, Plasma proteins, Composition and functions,
Microchips, Nanochips, Lab-on-a-Chip, Microfluidics, Micro- and Nano-LC systems,
Applications in different fields such as food, pharmaceuticals, petroleum, environmental and
other industrial sectors

Course Title ADVANCE ANALYTICAL CHEMISTRY LAB-II-B


Course Code CHEM-412-IIB
Credit Hours 3

1. Determination of free fat content in oil / milk


2. Determination of free fatty acids and acid values of biodiesel
3. Determination of saponification value
4. Determination of iodine value
5. Determination of phosphate content in commercial fertilizer samples by spectrophotometry
6. Determination of iron in food items
7. Determination of citric acid / ascorbic acid in juices / tablets
8. Determination of carbon dioxide in soft drinks
9. Iron in pharmaceutical samples
10. Quantification of proteins
11. Spectroscopic determination of lead in leaves using solvent extraction
12. Determination of heavy metals in biological samples
13. Small Research Projects

Course Title (Medicinal Chemistry) ORGANIC CHEMISTRY-I (Minor)


Course Code CHEM-462-I
Credit Hours 3

Medicinal Chemistry
Chemistry of biomolecules; introduction to drugs and drug discovery, sources of therapeutic
agents, structure activity relationship (SAR), drug-receptor interaction, drug formulation
and its methods, different types of drugs, chemistry and modes of action of some common
drugs.

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BS-CHEMISTRY 8th SEMESTER OUTLINE

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