Target

Beta-secretase 1
Cannabinoid receptor 1
Cathepsin D
Interleukin-8 receptor B
Interleukin-8 receptor A
MAP kinase p38 alpha
Serine/threonine-protein kinase PIM1
Vascular endothelial growth factor receptor 2
Renin
Cyclin-dependent kinase 2
Cyclin-dependent kinase 1
Serine/threonine-protein kinase PIM2
Serine/threonine-protein kinase PIM3
Tyrosine-protein kinase SYK
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Cyclin-dependent kinase 9
Proteasome subunit beta type-8
Cyclin-dependent kinase 2/cyclin E1
Hexokinase type IV
Cyclin-dependent kinase 5/CDK5 activator 1
Cyclooxygenase-2
Phosphodiesterase 5A
Cannabinoid receptor 2
Galanin receptor 1 (by homology)
Galanin receptor 2 (by homology)
c-Jun N-terminal kinase 3
MAP kinase ERK2
Serine/threonine-protein kinase Chk1
Neurokinin 2 receptor
Neurokinin 1 receptor
P2X purinoceptor 3
Probable G-protein coupled receptor 88
Sphingosine 1-phosphate receptor Edg-3
Leukotriene B4 receptor 1
Glucocorticoid receptor
Progesterone receptor
Matrix metalloproteinase 1
Prostaglandin E synthase
Epidermal growth factor receptor erbB1
Gamma-secretase
C-C chemokine receptor type 1
Complement factor D
Acetyl-CoA carboxylase 2
Thrombin
Poly [ADP-ribose] polymerase-1
PI3-kinase p110-gamma subunit
P-glycoprotein 1
Cyclin-dependent kinase 4/cyclin D1
Acetylcholinesterase
Histone deacetylase 6 (by homology)
Melatonin receptor 1A
Melatonin receptor 1B
Thrombin and coagulation factor X
Histone deacetylase 1
Cholesteryl ester transfer protein
Peptide N-myristoyltransferase 1
Serine/threonine-protein kinase Aurora-A
Tyrosine-protein kinase FYN
Tyrosine-protein kinase YES
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/
Dopamine D2 receptor
Serine/threonine-protein kinase Aurora-B
Dopamine D4 receptor
Dopamine D3 receptor
Tyrosine-protein kinase SRC
Signal transducer and activator of transcription 3
Phosphodiesterase 10A (by homology)
Dopamine D1 receptor
Serotonin 1a (5-HT1a) receptor
Serotonin 2a (5-HT2a) receptor
Serotonin 2c (5-HT2c) receptor
HERG
Phosphodiesterase 4D
Induced myeloid leukemia cell differentiation protein Mcl-1
Apoptosis regulator Bcl-2
Cholecystokinin A receptor
Cyclin-dependent kinase 5/CDK5 activator 1
Beta secretase 2
Cholecystokinin B receptor
Leucine-rich repeat serine/threonine-protein kinase 2
p53-binding protein Mdm-2
Serine/threonine-protein kinase B-raf
Proto-oncogene tyrosine-protein kinase ROS
Cyclin-dependent kinase 1/cyclin B1
Lysine-specific histone demethylase 1
Insulin-like growth factor I receptor
Protein farnesyltransferase
Protein kinase C delta
Corticotropin releasing factor receptor 1
Receptor protein-tyrosine kinase erbB-2
Fibroblast growth factor receptor 3
Melanin-concentrating hormone receptor 1
Cell division protein kinase 8
FK506-binding protein 1A
Peptidyl-prolyl cis-trans isomerase FKBP5
Estrogen receptor alpha
c-Jun N-terminal kinase 1
Estrogen receptor beta
Serine/threonine-protein kinase PLK1
Inhibitor of nuclear factor kappa B kinase epsilon subunit
 SwissTargetPrediction
Common name
BACE1
CNR1
CTSD
CXCR2
CXCR1
MAPK14
PIM1
KDR
REN
CDK2
CDK1
PIM2
PIM3
SYK
PFKFB3
CDK9
PSMB8
CCNE1 CDK2
GCK
CDK5
PTGS2
PDE5A
CNR2
GALR1
GALR2
MAPK10
MAPK1
CHEK1
TACR2
TACR1
P2RX3
GPR88
S1PR3
LTB4R
NR3C1
PGR
MMP1
PTGES
EGFR
PSEN2 PSENEN NCSTN APH1A PSEN1 APH1B
CCR1
CFD
ACACB
F2
PARP1
PIK3CG
ABCB1
CCND1 CDK4
ACHE
HDAC6
MTNR1A
MTNR1B
F10
HDAC1
CETP
NMT1
AURKA
FYN
YES1
NCOR2 HDAC3
DRD2
AURKB
DRD4
DRD3
SRC
STAT3
PDE10A
DRD1
HTR1A
HTR2A
HTR2C
KCNH2
PDE4D
MCL1
BCL2
CCKAR
CDK5R1 CDK5
BACE2
CCKBR
LRRK2
MDM2
BRAF
ROS1
CDK1 CCNB1
KDM1A
IGF1R
FNTA FNTB
PRKCD
CRHR1
ERBB2
FGFR3
MCHR1
CDK8
FKBP1A
FKBP5
ESR1
MAPK8
ESR2
PLK1
IKBKE
 SwissTargetPrediction
Uniprot ID ChEMBL ID
P56817 CHEMBL4822
P21554 CHEMBL218
P07339 CHEMBL2581
P25025 CHEMBL2434
P25024 CHEMBL4029
Q16539 CHEMBL260
P11309 CHEMBL2147
P35968 CHEMBL279
P00797 CHEMBL286
P24941 CHEMBL301
P06493 CHEMBL308
Q9P1W9 CHEMBL4523
Q86V86 CHEMBL5407
P43405 CHEMBL2599
Q16875 CHEMBL2331053
P50750 CHEMBL3116
P28062 CHEMBL5620
P24864 P24941 CHEMBL1907605
P35557 CHEMBL3820
Q00535 CHEMBL4036
P35354 CHEMBL230
O76074 CHEMBL1827
P34972 CHEMBL253
P47211 CHEMBL4894
O43603 CHEMBL3176
P53779 CHEMBL2637
P28482 CHEMBL4040
O14757 CHEMBL4630
P21452 CHEMBL2327
P25103 CHEMBL249
P56373 CHEMBL2998
Q9GZN0 CHEMBL3399910
Q99500 CHEMBL3892
Q15722 CHEMBL3911
P04150 CHEMBL2034
P06401 CHEMBL208
P03956 CHEMBL332
O14684 CHEMBL5658
P00533 CHEMBL203
P49810 Q9NZ42 Q92542 Q96BI3 P49768 Q8WW43 CHEMBL2094135
P32246 CHEMBL2413
P00746 CHEMBL2176771
O00763 CHEMBL4829
P00734 CHEMBL204
P09874 CHEMBL3105
P48736 CHEMBL3267
P08183 CHEMBL4302
P24385 P11802 CHEMBL1907601
P22303 CHEMBL220
Q9UBN7 CHEMBL1865
P48039 CHEMBL1945
P49286 CHEMBL1946
P00742 CHEMBL244
Q13547 CHEMBL325
P11597 CHEMBL3572
P30419 CHEMBL2593
O14965 CHEMBL4722
P06241 CHEMBL1841
P07947 CHEMBL2073
Q9Y618 O15379 CHEMBL2111363
P14416 CHEMBL217
Q96GD4 CHEMBL2185
P21917 CHEMBL219
P35462 CHEMBL234
P12931 CHEMBL267
P40763 CHEMBL4026
Q9Y233 CHEMBL4409
P21728 CHEMBL2056
P08908 CHEMBL214
P28223 CHEMBL224
P28335 CHEMBL225
Q12809 CHEMBL240
Q08499 CHEMBL288
Q07820 CHEMBL4361
P10415 CHEMBL4860
P32238 CHEMBL1901
Q15078 Q00535 CHEMBL1907600
Q9Y5Z0 CHEMBL2525
P32239 CHEMBL298
Q5S007 CHEMBL1075104
Q00987 CHEMBL5023
P15056 CHEMBL5145
P08922 CHEMBL5568
P06493 P14635 CHEMBL1907602
O60341 CHEMBL6136
P08069 CHEMBL1957
P49354 P49356 CHEMBL2094108
Q05655 CHEMBL2996
P34998 CHEMBL1800
P04626 CHEMBL1824
P22607 CHEMBL2742
Q99705 CHEMBL344
P49336 CHEMBL5719
P62942 CHEMBL1902
Q13451 CHEMBL2052031
P03372 CHEMBL206
P45983 CHEMBL2276
Q92731 CHEMBL242
P53350 CHEMBL3024
Q14164 CHEMBL3529
Target Class Probability* Known actives (3D/2D)
Protease 0.11573667475 890 / 0
Family A G protein-coupled receptor 0.11573667475 242 / 0
Protease 0.11573667475 294 / 0
Family A G protein-coupled receptor 0.11573667475 166 / 0
Family A G protein-coupled receptor 0.11573667475 82 / 0
Kinase 0.11573667475 270 / 0
Kinase 0.11573667475 94 / 0
Kinase 0.11573667475 331 / 0
Protease 0.11573667475 676 / 0
Kinase 0.11573667475 150 / 0
Kinase 0.11573667475 165 / 0
Kinase 0.11573667475 70 / 0
Kinase 0.11573667475 49 / 0
Kinase 0.11573667475 223 / 0
Enzyme 0.11573667475 130 / 0
Kinase 0.11573667475 46 / 0
Protease 0.11573667475 19 / 0
Kinase 0.11573667475 68 / 0
Enzyme 0.11573667475 83 / 0
Kinase 0.11573667475 33 / 0
Oxidoreductase 0.11573667475 38 / 0
Phosphodiesterase 0.11573667475 61 / 0
Family A G protein-coupled receptor 0.11573667475 224 / 0
Family A G protein-coupled receptor 0.11573667475 5 / 0
Family A G protein-coupled receptor 0.11573667475 5 / 0
Kinase 0.11573667475 69 / 0
Kinase 0.11573667475 255 / 0
Kinase 0.11573667475 61 / 0
Family A G protein-coupled receptor 0.11573667475 95 / 0
Family A G protein-coupled receptor 0.11573667475 113 / 0
Ligand-gated ion channel 0.11573667475 195 / 0
Family A G protein-coupled receptor 0.11573667475 9 / 0
Family A G protein-coupled receptor 0.11573667475 15 / 0
Family A G protein-coupled receptor 0.11573667475 31 / 0
Nuclear receptor 0.11573667475 144 / 0
Nuclear receptor 0.11573667475 40 / 0
Protease 0.11573667475 234 / 0
Enzyme 0.11573667475 21 / 0
Kinase 0.11573667475 299 / 0
Protease 0.11573667475 176 / 0
Family A G protein-coupled receptor 0.11573667475 174 / 0
Protease 0.11573667475 88 / 0
Ligase 0.11573667475 75 / 0
Protease 0.11573667475 110 / 0
Enzyme 0.11573667475 68 / 0
Enzyme 0.11573667475 121 / 0
Primary active transporter 0.11573667475 228 / 0
Kinase 0.11573667475 53 / 0
Hydrolase 0.11573667475 28 / 0
Eraser 0.11573667475 29 / 0
Family A G protein-coupled receptor 0.11573667475 11 / 0
Family A G protein-coupled receptor 0.11573667475 13 / 0
Protease 0.11573667475 219 / 0
Eraser 0.11573667475 28 / 0
Other ion channel 0.11573667475 20 / 0
Enzyme 0.11573667475 4 / 0
Kinase 0.11573667475 164 / 0
Kinase 0.11573667475 16 / 0
Kinase 0.11573667475 14 / 0
Eraser 0.11573667475 4 / 0
Family A G protein-coupled receptor 0.11573667475 203 / 0
Kinase 0.11573667475 113 / 0
Family A G protein-coupled receptor 0.11573667475 76 / 0
Family A G protein-coupled receptor 0.11573667475 106 / 0
Kinase 0.11573667475 143 / 0
Transcription factor 0.11573667475 8 / 0
Phosphodiesterase 0.11573667475 478 / 0
Family A G protein-coupled receptor 0.11573667475 20 / 0
Family A G protein-coupled receptor 0.11573667475 179 / 0
Family A G protein-coupled receptor 0.11573667475 141 / 0
Family A G protein-coupled receptor 0.11573667475 74 / 0
Voltage-gated ion channel 0.11573667475 211 / 0
Phosphodiesterase 0.11573667475 22 / 0
Other cytosolic protein 0.11573667475 3 / 0
Other ion channel 0.11573667475 75 / 0
Family A G protein-coupled receptor 0.11573667475 21 / 0
Kinase 0.11573667475 91 / 0
Protease 0.11573667475 80 / 0
Family A G protein-coupled receptor 0.11573667475 88 / 0
Kinase 0.11573667475 139 / 0
Other nuclear protein 0.11573667475 189 / 0
Kinase 0.11573667475 118 / 0
Kinase 0.11573667475 16 / 0
Other cytosolic protein 0.11573667475 32 / 0
Eraser 0.11573667475 5 / 0
Kinase 0.11573667475 173 / 0
Enzyme 0.11573667475 62 / 0
Kinase 0.11573667475 75 / 0
Family B G protein-coupled receptor 0.11573667475 88 / 0
Kinase 0.11573667475 73 / 0
Kinase 0.11573667475 8 / 0
Family A G protein-coupled receptor 0.11573667475 78 / 0
Kinase 0.11573667475 15 / 0
Isomerase 0.11573667475 16 / 0
Enzyme 0.11573667475 2 / 0
Nuclear receptor 0.11573667475 21 / 0
Kinase 0.11573667475 77 / 0
Nuclear receptor 0.11573667475 26 / 0
Kinase 0.11573667475 11 / 0
Kinase 0.11573667475 23 / 0