Target

Kinesin-like protein 1
Monoamine oxidase A
Beta-secretase 1
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET
Neuropeptide Y receptor type 5
Phosphodiesterase 10A
Lysine-specific demethylase 4D-like
Thrombin and coagulation factor X
3-phosphoinositide dependent protein kinase-1
Lysine-specific demethylase 4A
Lysine-specific demethylase 4C
ADAMTS5
Cannabinoid receptor 1
Myosin light chain kinase, smooth muscle
Leukocyte elastase
Cathepsin K
Cathepsin S
Arachidonate 12-lipoxygenase
Cathepsin L
Cathepsin (B and K)
Hepatocyte growth factor receptor
Signal transducer and activator of transcription 6
Cyclin-dependent kinase 4/cyclin D1
Epidermal growth factor receptor erbB1
Cyclin-dependent kinase 2/cyclin E
Adenosine A1 receptor
Adenosine A2a receptor
Matrix metalloproteinase 13
Matrix metalloproteinase 9
Matrix metalloproteinase 1
ADAM17
Cystic fibrosis transmembrane conductance regulator
Beta secretase 2
Cytochrome P450 19A1
Vascular endothelial growth factor receptor 2
Arachidonate 15-lipoxygenase
Metabotropic glutamate receptor 2
Tyrosine-protein kinase receptor FLT3
Calpain 2
Cholecystokinin B receptor
Cell division protein kinase 8
GABA-A receptor; GABA-A site (alpha1/beta2 interface)
Sodium channel protein type V alpha subunit
2-acylglycerol O-acyltransferase 2
Sodium channel protein type II alpha subunit
ALK tyrosine kinase receptor
Neurokinin 3 receptor
Leucine-rich repeat serine/threonine-protein kinase 2
Thymidylate synthase
Vitamin D receptor
Somatostatin receptor 3
Neurogenic locus notch homolog protein 1
HERG
Neurogenic locus notch homolog protein 3
MAP kinase ERK2
Leukotriene A4 hydrolase
Vanilloid receptor
Serine/threonine-protein kinase B-raf
Endothelial PAS domain-containing protein 1
GABA receptor alpha-1 subunit (by homology)
Gamma-secretase
GABA receptor alpha-5 subunit (by homology)
Carnitine O-palmitoyltransferase 1, liver isoform
Thromboxane-A synthase
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
Tyrosine-protein kinase ITK/TSK
Carnitine palmitoyltransferase 2
Cyclin-dependent kinase 2
Adenosine A3 receptor
Cytochrome P450 11B1
Cytochrome P450 11B2
Melatonin receptor 1A
Melatonin receptor 1B
Matrix metalloproteinase 16
Tyrosine-protein kinase SRC
Matrix metalloproteinase 3
Protein kinase C gamma (by homology)
Matrix metalloproteinase 2
Matrix metalloproteinase 14
P-glycoprotein 1
Matrix metalloproteinase 12
Matrix metalloproteinase 8
Dopamine D2 receptor (by homology)
c-Jun N-terminal kinase 1
c-Jun N-terminal kinase 3
DNA-dependent protein kinase
Cyclin-dependent kinase 4
c-Jun N-terminal kinase 2
Orexin receptor 2
Orexin receptor 1
Calcium sensing receptor
Cyclin-dependent kinase 5/CDK5 activator 1
Aminopeptidase N
Arachidonate 5-lipoxygenase
Muscarinic acetylcholine receptor M1 (by homology)
Tyrosine-protein kinase LCK (by homology)
Nerve growth factor receptor Trk-A
Toll-like receptor 4
Mitogen-activated protein kinase kinase kinase 5
Serine/threonine-protein kinase RAF
 SwissTargetPrediction
Common name
KIF11
MAOA
BACE1
RET
NPY5R
PDE10A
KDM4E
F10
PDPK1
KDM4A
KDM4C
ADAMTS5
CNR1
MYLK
ELANE
CTSK
CTSS
ALOX12
CTSL
CTSB
MET
STAT6
CCND1 CDK4
EGFR
CCNE2 CDK2 CCNE1
ADORA1
ADORA2A
MMP13
MMP9
MMP1
ADAM17
CFTR
BACE2
CYP19A1
KDR
ALOX15
GRM2
FLT3
CAPN2
CCKBR
CDK8
GABRA1 GABRB2
SCN5A
MOGAT2
SCN2A
ALK
TACR3
LRRK2
TYMS
VDR
SSTR3
NOTCH1
KCNH2
NOTCH3
MAPK1
LTA4H
TRPV1
BRAF
EPAS1
GABRA1
PSEN2 PSENEN NCSTN APH1A PSEN1 APH1B
GABRA5
CPT1A
TBXAS1
PFKFB3
ITK
CPT2
CDK2
ADORA3
CYP11B1
CYP11B2
MTNR1A
MTNR1B
MMP16
SRC
MMP3
PRKCG
MMP2
MMP14
ABCB1
MMP12
MMP8
DRD2
MAPK8
MAPK10
PRKDC
CDK4
MAPK9
HCRTR2
HCRTR1
CASR
CDK5R1 CDK5
ANPEP
ALOX5
CHRM1
LCK
NTRK1
TLR4
MAP3K5
RAF1
 SwissTargetPrediction
Uniprot ID ChEMBL ID
P52732 CHEMBL4581
P21397 CHEMBL1951
P56817 CHEMBL4822
P07949 CHEMBL2041
Q15761 CHEMBL4561
Q9Y233 CHEMBL4409
B2RXH2 CHEMBL1293226
P00742 CHEMBL244
O15530 CHEMBL2534
O75164 CHEMBL5896
Q9H3R0 CHEMBL6175
Q9UNA0 CHEMBL2285
P21554 CHEMBL218
Q15746 CHEMBL2428
P08246 CHEMBL248
P43235 CHEMBL268
P25774 CHEMBL2954
P18054 CHEMBL3687
P07711 CHEMBL3837
P07858 CHEMBL4072
P08581 CHEMBL3717
P42226 CHEMBL5401
P24385 P11802 CHEMBL1907601
P00533 CHEMBL203
O96020 P24941 P24864 CHEMBL2094126
P30542 CHEMBL226
P29274 CHEMBL251
P45452 CHEMBL280
P14780 CHEMBL321
P03956 CHEMBL332
P78536 CHEMBL3706
P13569 CHEMBL4051
Q9Y5Z0 CHEMBL2525
P11511 CHEMBL1978
P35968 CHEMBL279
P16050 CHEMBL2903
Q14416 CHEMBL5137
P36888 CHEMBL1974
P17655 CHEMBL2382
P32239 CHEMBL298
P49336 CHEMBL5719
P14867 P47870 CHEMBL1907597
Q14524 CHEMBL1980
Q3SYC2 CHEMBL2439944
Q99250 CHEMBL4187
Q9UM73 CHEMBL4247
P29371 CHEMBL4429
Q5S007 CHEMBL1075104
P04818 CHEMBL1952
P11473 CHEMBL1977
P32745 CHEMBL2028
P46531 CHEMBL2146346
Q12809 CHEMBL240
Q9UM47 CHEMBL3407319
P28482 CHEMBL4040
P09960 CHEMBL4618
Q8NER1 CHEMBL4794
P15056 CHEMBL5145
Q99814 CHEMBL1744522
P14867 CHEMBL1962
P49810 Q9NZ42 Q92542 Q96BI3 P49768 Q8WW43 CHEMBL2094135
P31644 CHEMBL5112
P50416 CHEMBL1293194
P24557 CHEMBL1835
Q16875 CHEMBL2331053
Q08881 CHEMBL2959
P23786 CHEMBL3238
P24941 CHEMBL301
P0DMS8 CHEMBL256
P15538 CHEMBL1908
P19099 CHEMBL2722
P48039 CHEMBL1945
P49286 CHEMBL1946
P51512 CHEMBL2200
P12931 CHEMBL267
P08254 CHEMBL283
P05129 CHEMBL2938
P08253 CHEMBL333
P50281 CHEMBL3869
P08183 CHEMBL4302
P39900 CHEMBL4393
P22894 CHEMBL4588
P14416 CHEMBL217
P45983 CHEMBL2276
P53779 CHEMBL2637
P78527 CHEMBL3142
P11802 CHEMBL331
P45984 CHEMBL4179
O43614 CHEMBL4792
O43613 CHEMBL5113
P41180 CHEMBL1878
Q15078 Q00535 CHEMBL1907600
P15144 CHEMBL1907
P09917 CHEMBL215
P11229 CHEMBL216
P06239 CHEMBL258
P04629 CHEMBL2815
O00206 CHEMBL5255
Q99683 CHEMBL5285
P04049 CHEMBL1906
Target Class Probability*
Other cytosolic protein 0.101613854776
Oxidoreductase 0.101613854776
Protease 0.101613854776
Kinase 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Phosphodiesterase 0.101613854776
Eraser 0.101613854776
Protease 0.101613854776
Kinase 0.101613854776
Eraser 0.101613854776
Eraser 0.101613854776
Protease 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Enzyme 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Kinase 0.101613854776
Transcription factor 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Other cytosolic protein 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Other ion channel 0.101613854776
Protease 0.101613854776
Cytochrome P450 0.101613854776
Kinase 0.101613854776
Enzyme 0.101613854776
Family C G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Protease 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Ligand-gated ion channel 0.101613854776
Voltage-gated ion channel 0.101613854776
Transferase 0.101613854776
Voltage-gated ion channel 0.101613854776
Kinase 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Transferase 0.101613854776
Nuclear receptor 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Unclassified protein 0.101613854776
Voltage-gated ion channel 0.101613854776
Unclassified protein 0.101613854776
Kinase 0.101613854776
Protease 0.101613854776
Voltage-gated ion channel 0.101613854776
Kinase 0.101613854776
Unclassified protein 0.101613854776
Ligand-gated ion channel 0.101613854776
Protease 0.101613854776
Ligand-gated ion channel 0.101613854776
Enzyme 0.101613854776
Cytochrome P450 0.101613854776
Enzyme 0.101613854776
Kinase 0.101613854776
Enzyme 0.101613854776
Kinase 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Cytochrome P450 0.101613854776
Cytochrome P450 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Protease 0.101613854776
Kinase 0.101613854776
Protease 0.101613854776
Kinase 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Primary active transporter 0.101613854776
Protease 0.101613854776
Protease 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Family C G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Protease 0.101613854776
Oxidoreductase 0.101613854776
Family A G protein-coupled receptor 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Toll-like and Il-1 receptors 0.101613854776
Kinase 0.101613854776
Kinase 0.101613854776
Known actives (3D/2D)
57 / 0
160 / 0
713 / 0
109 / 0
295 / 0
1130 / 0
6/ 0
336 / 0
109 / 0
6/ 0
13 / 0
53 / 0
952 / 0
22 / 0
148 / 0
387 / 0
314 / 0
16 / 0
239 / 0
220 / 0
509 / 0
9/ 0
101 / 0
755 / 0
99 / 0
716 / 0
561 / 0
205 / 0
254 / 0
273 / 0
125 / 0
27 / 0
155 / 0
274 / 0
891 / 0
30 / 0
43 / 0
197 / 0
47 / 0
444 / 0
19 / 0
6/ 0
23 / 0
18 / 0
37 / 0
127 / 0
124 / 0
115 / 0
73 / 0
18 / 0
31 / 0
2/ 0
214 / 0
2/ 0
268 / 0
23 / 0
460 / 0
243 / 0
1/ 0
37 / 0
308 / 0
28 / 0
105 / 0
24 / 0
159 / 0
79 / 0
18 / 0
266 / 0
343 / 0
142 / 0
149 / 0
416 / 0
374 / 0
5/ 0
317 / 0
181 / 0
58 / 0
221 / 0
28 / 0
78 / 0
19 / 0
114 / 0
271 / 0
352 / 0
231 / 0
117 / 0
93 / 0
149 / 0
745 / 0
640 / 0
37 / 0
261 / 0
15 / 0
143 / 0
67 / 0
173 / 0
209 / 0
35 / 0
5/ 0
107 / 0