B.tech - Biotechnology (Syllabus) 2018
B.tech - Biotechnology (Syllabus) 2018
Course Objective:
The objective of this course module is to acquaint the students with the basics of computers system, its
components, data representation inside computer and to get them familiar with various important features
of procedure oriented programming language i.e. C.
Course Contents:
Module I: Introduction
Introduction to computer, history, von-Neumann architecture, memory system (hierarchy, characteristics
and types), H/W concepts (I/O Devices), S/W concepts (System S/W & Application S/W, utilities). Data
Representation: Number systems, character representation codes, Binary, octal, hexadecimal and their
interconversions. Binary arithmetic, floating point arithmetic, signed and unsigned numbers, Memory
storage unit.
Examination Scheme:
Components A CT S/V/Q HA EE
Weightage (%) 5 10 8 7 70
1
CT: Class Test, HA: Home Assignment, S/V/Q: Seminar/Viva/Quiz, EE: End Semester Examination; Att:
Attendance
Herbert Schildt, “C: The complete reference”, Osbourne Mcgraw Hill, 4 Edition, 2002.
th
References:
Kernighan & Ritchie, “C Programming Language”, The (Ansi C Version), PHI, 2nd Edition.
J. B Dixit, “Fundamentals of Computers and Programming in „C‟.
P.K. Sinha and Priti Sinha, “Computer Fundamentals”, BPB publication.
2
3
PROGRAMMING IN C LAB
Course Code: BTE2108 Credit Units: 01
Course Contents:
C program involving problems like finding the nth value of cosine series, Fibonacci series. Etc.
C programs including user defined function calls
C programs involving pointers, and solving various problems with the help of those.
File handling
Examination Scheme:
IA EE
A PR LR V PR V
5 10 10 5 35 35
Note: IA –Internal Assessment, EE- External Exam, PR- Performance, LR – Lab Record, V – Viva.
Syllabus – Second Semester
Course Objective:
The objective of this module is to introduce object oriented programming. To explore and implement the
various features of OOP such as inheritance, polymorphism, Exceptional handling using programming
language C++. After completing this course student can easily identify the basic difference between the
programming approaches like procedural and object oriented.
Course Contents:
Module I: Introduction
Review of C, Difference between C and C++, Procedure Oriented and Object Oriented Approach. Basic
Concepts: Objects, classes, Principals like Abstraction, Encapsulation, Inheritance and Polymorphism.
Dynamic Binding, Message Passing. Characteristics of Object-Oriented Languages.Introduction to
Object-Oriented Modeling techniques (Object, Functional and Dynamic Modeling).
Examination Scheme:
Components A CT S/V/Q HA EE
Weightage (%) 5 10 8 7 70
Course Contents:
Creation of objects in programs and solving problems through them.
Different use of private, public member variables and functions and friend functions.
Use of constructors and destructors.
Operator overloading
Use of inheritance in and accessing objects of different derived classes.
Polymorphism and virtual functions (using pointers).
File handling.
Examination Scheme:
IA EE
A PR LR V PR V
5 10 10 5 35 35
Note: IA –Internal Assessment, EE- External Exam, PR- Performance, LR – Lab
Syllabus – Third Semester
BIOSTATISTICS
Course Code: BTE2303 Credit Units: 03
Course Objective:
The course aims to develop competency and expertise in the application of statistical methods applied to
biological data obtained in experimental techniques, methodology and the safe laboratory practice.
Course Contents:
Module I
Statistics and Biostatistics: Preliminary concepts; Measures of Central Tendency: Mean, Median, Mode
Measures of Dispersion: Range, Standard deviation, Variance
Module V: Regression
Definition, Regression lines and Regression Coefficients, Properties of Regression Coefficients, Some
examples. Method of least square: Fitting of straight line
Examination Scheme:
References:
Biostatistics: A manual of Statistical Methodology for use in Health, Nutrition and Anthropology, K.
Visweswara Rao. Publisher: Jaypee Brothers Biostatistics: A foundation for analysis in the Health
Sciences, W.W. Daniel, Publisher: John Wiley and Sons
Fundamentals of Mathematical Statistics, S.C. Gupta and V.K. Kapoor, Publisher: S.Chand & Co.
Statistical Analysis, Kaushal, T.L. Publisher: Kalyani Publishers
Statistical Methods, Potri, D. Kalyani Publishers.
Mathematical Statistics, H.C. Saxena, and V.K. Kapoor: S. Chand & Company
Biostatistics, P.N. Arora and P.K. Malhan, Publisher: Himalaya Publishing House.
DATABASE MANAGEMENT SYSTEM
Course Code: BTE2304 Credit Units: 02
Course Objective:
It enables the students to access biological information networks and databases in order to understand the
different techniques of biotechnology to build detection systems especially in the prevention and
treatment of human diseases.
Course Contents:
Examination Scheme:
Text:
Data Mining: Concept and techniques, J. Han and M. Kamber, Morgan Kaufman.
Database Management, P.C. Desai.
References:
Introduction to Database Systems, C.J. Date, Addison Wesley Publishing.
Data Mining, A.K. Pujari, Sangam Books Ltd.
Principles of Database and Knowledge Based systems, J.D. Ullman, Computer Science Press.
The Data Warehouse Lifecycle Toolkit, John Wiley and Sons Inc.
The Data Warehouse Toolkit, R. Kimball et al, John Wiley and Sons Inc.
DATABASE MANAGEMENT SYSTEMS LAB
Course Code: BTE2308 Credit Units: 01
Course Contents:
Module I
Database creation using DDL and DML.
Module II
Defining the primary and secondary keys.
Module III
Implementation of selection, projection and joins (internal and external) with SQL and Perl .
Module IV
Normalization of databases with SQL and Perl
Module V
Implementation of transactions and schedules.
Module VI
Detection of association rules and knowledge recovery.
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
Note: Minor variation could be there depending on the examiner
INDUSTRIAL BIOTECHNOLOGY
Course Code:BTE2309 Credit Units: 02
Course Objective:
The objective of this course is to use microorganism to produce various compounds of commercial
interest. The student will be exposed to various techniques available for large scale cultivation of
microorganisms.
Course Contents:
Module I
Introduction to fermentation, the fermentation industry, Production process batch and Continuous system
of cultivation, Solid-state fermentation
Module II
Selection of industrial microorganisms, media for fermentation, aeration, pH, temperature and other
requirements during fermentation, downstream processing and product recovery, food industry waste as
fermentation substrate.
Module III
Production of compounds like, antibiotics, enzymes, organic acids, solvents, beverages, SCP.
Module IV
Production of fermented dairy products
Module V
Immobilized enzymes systems, production and applications.
Examination Scheme:
Text:
Industrial Microbiology – Cassida
References:
Principles of fermentation Technology, Salisbury, Whitaker and Hall
Industrial microbiology – Prescot & Duhn.
FERMENTATION TECHNOLOGY
Course Code: BTE2310 Credit Units: 02
Objective of the course is for the acquaintance of large scale cultivation of microbes for production of
industrially important products.
Course Contents
Examination Scheme:
Text &references:
Text:
Principles of Fermentation Technology by P.F. Stanbury, A. Whitaker, and S.J. Hall, Aditya Books
(P) LTD.
Industrial Microbiology by L.E.Casida, JR. New Age International (P) LTD.
Biotechnology, A Text book of Industrial Microbiology, W. Crueger and A. Crueger, Sinauer
Association.
References:
Practical Biochemistry, Principles & Techniques, Keith Wilson and John Walker
Biochemical Engineering Fundamentals, J.E. Bailey and D.F. Ollis, McGraw-Hill
Protein Purification, M.R. Ladisch, R.C. Wilson, C.C. Painton and S.E. Builder, American Chemical
Society
DRUG DESIGN AND DEVELOPMENT
Course Code: BTE2311 Credit Units: 02
Course Objective:
The above course will be aimed to identify and design drugs that could be potentially useful in the
identification of the candidate drugs, which have efficacy in cell culture or animal models, and thus the
most effective compounds could be employed based on the above results for being moved through
preclinical studies to clinical trials.
Course Contents:
Examination Scheme:
Text:
Drug Delivery and Targeting, A.M. Hillery, A.W. Lloyd and J. Swarbrick, Harwood Academic
Publisher
Pharmaceutical Dosage Forms and Drug Delivery Systems, H.C. Ansel, L.V. allen and N.G.
Popovich, Lippincott Williams and Wilkins Publisher
References:
Introduction to Biophysical Methods for Protein and Nucleic Acid Research, J.A. Glasel and M.P.
Deutscher, Academic Press.
Principles of Drug Action, W.B. Pratt and P. Taylor, Churchill Livingston.
Principles of Medicinal Chemistry, W.O. Foye, T.L. Lemke, and D.A. Williams, Williams and
Wilkins
Side Effects and Drug Design, E.J. Lien, Marcel Dekker.
The Anticancer Drugs, W.B. Pratt, R.W. Ruddon, W.D. Ensminger, and J. Maybaum, Oxford
University Press.
RECOMBINANT DNA TECHNOLOGY
Course Code:BTE2312 Credit Units: 02
Course Objective:
A complete understanding of molecular techniques like DNA sequencing, restriction mapping, PCR for
the cloning and expression of genes can be obtained through the course.
Course Contents:
Module I
Purification of DNA from bacterial, plant and animal cells, manipulation of purified DNA.
Module II
Introduction of DNA into living cells
Module III
Introduction to gene cloning and its uses, tools and techniques: plasmids and other vectors, DNA, RNA,
cDNA.
Module IV
Production of proteins from cloned genes: gene cloning in medicine (Pharmaceutical agents such as
insulin, growth hormones, recombinant vaccines), gene therapy for genetic diseases.
Module V
Analysis of DNA by Southern blotting, Analysis of RNA by Northern blotting, Analysis of proteins by
Western blot techniques, Dot blots and slot blots, RFLP, AFLP.
PCR: Basic principles and its modification application and uses.
Examination Scheme:
Text:
Gene cloning and DNA analysis by T.A. Brown
References:
Recombinant DNA, J.D. Watson et al, W.H. Freeman and Company
Principles of Gene Manipulation: An Introduction to Genetic Engineering, R.W. Old and S. B
Primrose, Blackwell Science Inc
Molecular Biotechnology: Principles and Applications of Recombinant DNA, B.R. Grick and J.J.
Pasternak, ASM Press
Molecular Biology of gene by Watson, Baker, Bell, Gann, Levine, Losick
DNA Science by Micklos Freyer
Principles of Gene manipulation and Genomics by Primrose and Twyman
TERM PAPER
Course Code: BTE2331 Credit Units: 02
METHODOLOGY
A term (or research) paper is primarily a record of intelligent reading in several sources on a particular
subject.
The students will choose the topic at the beginning of the session in consultation with the faculty
assigned. The progress of the paper will be monitored regularly by the faculty. At the end of the semester
the detailed paper on the topic will be submitted to the faculty assigned. The evaluation will be done by
Board of examiners comprising of the faculties.
1. Choosing a Subject
The subject chosen should not be too general.
Discussion
The discussion section either follows the results or may alternatively be integrated in the results section.
The section should consist of a discussion of the results of the study focusing on the question posed in the
research paper.
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded.
There are a number of key components which should not be omitted. These include:
a) summary of question posed
b) summary of findings
c) summary of main limitations of the study at hand
d) details of possibilities for related future research
References
From the very beginning of a research project, you should be careful to note all details of articles
gathered.
The bibliography should contain ALL references included in the paper. References not included in the
text in any form should NOT be included in the bibliography.
The key to a good bibliography is consistency. Choose a particular convention and stick to this.
Bibliographical conventions
Monographs
Crystal, D. (2001), Language and the internet. Cambridge: Cambridge University Press.
Edited Volumes
Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second
language. Berlin/ NY: Mouton de Gruyter.
[(eds.) is used when there is more than one editor; and (ed.) where there is only one editor. In German the
abbreviation used is (Hrsg.) for Herausgeber].
Edited Articles
Schmidt, R./Shimura, A./Wang, Z./Jeong, H. (1996), Suggestions to buy: Television commercials from
the U.S., Japan, China, and Korea. In: Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures.
Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter: 285-316.
Journal Articles
McQuarrie, E.F./Mick, D.G. (1992), On resonance: A critical pluralistic inquiry into advertising rhetoric.
Journal of consumer research 19, 180-197.
Electronic Book
Chandler, D. (1994), Semiotics for beginners [HTML document]. Retrieved [5.10.'01] from the World
Wide Web, http://www.aber.ac.uk/media/Documents/S4B/.
Other Websites
Verterhus, S.A. (n.y.), Anglicisms in German car advertising. The problem of gender assignment [HTML
document]. Retrieved [13.10.'01] from the World Wide Web, http://olaf.hiof.no/~sverrev/eng.html.
Unpublished Papers
Takahashi, S./DuFon, M.A. (1989), Cross-linguistic influence in indirectness: The case of English
directives performed by native Japanese speakers. Unpublished paper, Department of English as a Second
Language, University of Hawai'i at Manoa, Honolulu.
Appendix
The appendix should be used for data collected (e.g. questionnaires, transcripts,...) and for tables and
graphs not included in the main text due to their subsidiary nature or to space constraints in the main text.
Assessment Scheme:
Objectives:
The aim of the project is to provide the students with an opportunity to further their intellectual and
personal development in the chosen field by undertaking a significant practical unit of activity. The
project can be defined as a scholarly inquiry into a problem or issues, involving a systematic approach to
gathering and analysis of information / data, leading to production of a structured report.
1) Cover Page: This should contain the title of the project proposal, to whom it is submitted, for which
degree, the name of the author, name of the supervisor, year of submission of the project work, name of
the University.
2) Acknowledgement: Various organizations and individuals who might have provided assistance /co-
operation during the process of carrying out the study.
3) Table of Content: Page-wise listing of the main contents in the report, i.e., different Chapters and its
main Sections along with their page numbers.
4) Body of the Report: The body of the report should have these four logical divisions
a) Introduction: This will cover the background, rationale/ need / justification, brief review of literature,
objectives, methodology (the area of the study, sample, type of study, tools for data collection, and
method of analysis), Limitations of the Study, and Chapter Planning.
b) Conceptual Framework / National and International Scenario: (relating to the topic of the Project).
c) Presentation of Data,Analysis and Findings:(using the tools and techniques mentioned in the
methodology).
d) Conclusion and Recommendations: In this section, the concluding observations based on the main
findings and suggestions are to be provided.
5) Bibliography or References: This section will include the list of books and articles which have been
used in the project work, and in writing a project report.
Step I : Selection of the topic for the project by taking following points into consideration:
Suitability of the topic.
Relevance of the topic
Time available at the disposal.
Feasibility of data collection within the given time limit.
Challenges involved in the data collection (time & cost involved in the data collection, possibility
of getting responses, etc.)
Step II : Finalisation of the Topic and preparation of Project Proposal in consultation with the Supervisor.
Step III : Collection of information and data relating to the topic and analysis of the same.
Step IV: Writing the report dividing it into suitable chapters, viz.,
Chapter 1: Introduction,
Chapter 2: Conceptual Framework / National & International Scenario,
Chapter 3: Analysis & Findings
Chapter 4: Conclusion and Recommendations.
Step V: The following documents are to be attached with the Final Project Report.
1) Approval letter from the supervisor (Annexure-IA)
2) Student‟s declaration (Annexure-IB)
3) Certificate from the Competent Authority of the Organisation / Institution, if the student
undertakes the Project Work in any Organisation / Institution.
Objectives
A workshop is primarily an activity based academic event that is organized to provide the students a one
to one and hands on experience on any aspect of their learning. The communication in a workshop has to
be necessarily two way. The trainer has to make sure that the aspect covered are practically practiced by
the participants. The student will choose the option of workshop from amongst their concentration
electives. The evaluation will be done by Board of examiners comprising of the faculties.
Methodology
The methodology followed at the workshop could be based on any one or more of the following methods:
Case Study
Business Game
Simulation
Group Activity
Role Play
Business Planning
Quiz
Evaluation Scheme:
Attendance Active Multiple Choice Solving the case/ Total
Participation Questions/ Quiz Assignment/
Write up
10 30 30 30 100
Syllabus – Fourth Semester
MICROBIOLOGY LAB
Course Code: BTE2406 Credit Units: 02
Course Contents:
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
DATA STRUCTURE& ALGORITHMS LAB
Course Code: BTE2407 Credit Units: 01
Course Contents:
Module I
Stack implementation through arrays, link list
Module II
Programs for recursion functions
Module III
Implementation of queues and leap structures
Module IV
Application of binary trees in pre-order, post-order and in-order evaluation
Module V
A VL tree implementation
Module VI
Optimal matrix multiplication
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
ENZYMOLOGY AND ENZYME TECHNOLOGY LAB
Course Code: BTE2408 Credit Units: 01
Course Objective:
The laboratory will help the students to isolate enzymes from different sources, enzyme assays and
studying their kinetic parameters which have immense importance in industrial processes.
Course Contents:
Module I
Isolation of enzymes from plant and microbial sources.
Module II
Enzyme assay; activity and specific activity – determination of amylase, nitrate reductase, cellulase,
protease.
Module III
Purification of Enzyme by ammonium sulphate fractionation.
Module IV
Enzyme Kinetics: Effect of varying substrate concentration on enzyme activity, determination of
Michaelis-Menten constant (Km) and Maximum Velocity (Vmax.) using Lineweaver-Burk plot.
Module V
Effect of Temperature and pH on enzyme activity.
Module VI
Enzyme immobilization
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
Text:
Practical Biochemistry, Sawhney and Singh
References:
Practical Biochemistry, Principles & Techniques, Keith Wilson and John Walker
METHODS AND INSTRUMENTATION IN BIOTECHNOLOGY LAB
Course Code: BTE2409 Credit Units: 01
Course Contents:
Module I
Cell disruption techniques
Module II
Centrifugation – low speed and high speed.
Module III
Spectrophotometer techniques
Module IV
Chromatography –Paper Chromatography and Thin Layer Chromatography
Module V
Electrophoresis –SDS Page and Agarose gel electrophoresis.
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
MARINE BIOTECHNOLOGY
Course Code: BTE2410 Credit Units: 02
Course Objective
The students will be exposed to basic concepts related to marine life. Also the subject deals with the
scope and application of marine biota in biotechnology.
Course Contents
Module I
The marine ecosystem and its functioning: intertidal, estuarine, salt marsh, mangrove, coral reef, coastal
& deep sea ecosystems. Marine viruses, Bacteria and their significance; Hydrothermal vents; Marine
Biodiversity: defining, measurement and conservation strategies.
Module II
Nutrients cycling: carbon, nitrogen sulphur & phosphorus.
Global climate changes: impact on species diversity & productivity, oceans as a carbon sink, effects on
corals bleaching. Biological rhythms.
Module III
Important Marine Products: Bioactive compounds from marine organisms, GFP, RFP characteristics and
their applications; Green mussel adhesive protein, Chitosan and its applications
Module IV
Probiotic bacteria and their importance in aquaculture; Vaccines in aquaculture: Fish, shrimps & prawns;
Marine food analysis-spoilage, quality control; Techniques for identification of bacterial & viral
pathogens in aquaculture and Remedies.
Examination Scheme:
Course Objective
The students will be exposed to basic concepts related with development of vaccines.
Course Contents
Module I
History of Vaccine Development
Definition of Vaccine
Evolution of Vaccines
Module II
Process development for vaccines
Manufacturing of vaccines
Various aspects of vaccines, process development and manufacturing
Module III
Clinical development of vaccines
Clinical end-point: Evolution of vaccines
General specifications and pharmaceuticals release criteria for the existing vaccines
Cold chain management of vaccines
Current vaccine research
Examination Scheme:
Components H/S A CT EE
Weightage (%) 10 5 15 70
Course Objective:
The agriculture plant biotechnology course basically meant for understanding the basic techniques of
plant tissue culture and genetic engineering in plants along with the latest ongoing research on the
different aspects of plants and its products to redefine agriculture priorities and produce human resource
with academic, scientific and technical expertise along with management or business experience.
Examination Scheme:
Components H/S A CT EE
Weightage (%) 10 5 15 70
References
Course Objective: The objective of this paper is to familiarize the students with stem cell technology and
its applications for betterment of the society. The course is designed to give a broad view of mammalian
stem cells, reviewing where they are found in the body, the different types and how they are cultured. The
topics will cover the basic biology of these stem cells as well as bioengineering and application of these
stem cells to potential treatments of human diseases.
Course Contents:
Module I
Definition, properties, proliferation, culture of stem cells, medical applications of stem cells, ethical and
legal issues in use of stem cells.
Module II
Stem Cell biology and therapy, types embryonic stem cell, Adult stem cell, Stem Cell Biology and
Therapy, Embryonic Stem Cells, culture and the potential benefits of stem cell technology
Module III
Gene Therapy: Introduction, History and evolution of Gene therapy, optimal disease targets, Failures and
successes with gene therapy and future prospects,Genetic Perspectives for Gene Therapy, Gene Delivery
methods: Viral vectors and Non-viral Vectors
Module IV
Regulatory and Ethical Considerations of stem cell and Gene Therapy, Assessing Human Stem Cell
Safety, Use of Genetically Modified Stem Cells in Experimental Gene Therapies.
Examination Scheme:
References:
Stem Cell Biology and Gene Therapy. Quesenberry PJ, Stein GS, eds. (£65.00.) Wiley, 1998.
Progress in gene therapy, Volume 2,Pioneering stem cell/gene therapy trials, Roger Bertolotti, Keiya
Ozawa and H. Kirk Hammond, VSP international science publishers
Stem Cells Handbook: Stewart Sell, Humana Press; Totowa NJ, USA; Oct. 2003,
Understanding Biotechnology by Aluízio Borém, Fabrício R. Santos, David E. Bowen, Prentice Hall
TERM PAPER
Course Code: BTE2431 Credit Units: 02
METHODOLOGY
A term (or research) paper is primarily a record of intelligent reading in several sources on a particular
subject.
The students will choose the topic at the beginning of the session in consultation with the faculty
assigned. The progress of the paper will be monitored regularly by the faculty. At the end of the semester
the detailed paper on the topic will be submitted to the faculty assigned. The evaluation will be done by
Board of examiners comprising of the faculties.
1. Choosing a Subject
The subject chosen should not be too general.
Discussion
The discussion section either follows the results or may alternatively be integrated in the results section.
The section should consist of a discussion of the results of the study focusing on the question posed in the
research paper.
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded.
There are a number of key components which should not be omitted. These include:
e) summary of question posed
f) summary of findings
g) summary of main limitations of the study at hand
h) details of possibilities for related future research
References
From the very beginning of a research project, you should be careful to note all details of articles
gathered.
The bibliography should contain ALL references included in the paper. References not included in the
text in any form should NOT be included in the bibliography.
The key to a good bibliography is consistency. Choose a particular convention and stick to this.
Bibliographical conventions
Monographs
Crystal, D. (2001), Language and the internet. Cambridge: Cambridge University Press.
Edited Volumes
Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second
language. Berlin/ NY: Mouton de Gruyter.
[(eds.) is used when there is more than one editor; and (ed.) where there is only one editor. In German the
abbreviation used is (Hrsg.) for Herausgeber].
Edited Articles
Schmidt, R./Shimura, A./Wang, Z./Jeong, H. (1996), Suggestions to buy: Television commercials from
the U.S., Japan, China, and Korea. In: Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures.
Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter: 285-316.
Journal Articles
McQuarrie, E.F./Mick, D.G. (1992), On resonance: A critical pluralistic inquiry into advertising rhetoric.
Journal of consumer research 19, 180-197.
Electronic Book
Chandler, D. (1994), Semiotics for beginners [HTML document]. Retrieved [5.10.'01] from the World
Wide Web, http://www.aber.ac.uk/media/Documents/S4B/.
Other Websites
Verterhus, S.A. (n.y.), Anglicisms in German car advertising. The problem of gender assignment [HTML
document]. Retrieved [13.10.'01] from the World Wide Web, http://olaf.hiof.no/~sverrev/eng.html.
Unpublished Papers
Takahashi, S./DuFon, M.A. (1989), Cross-linguistic influence in indirectness: The case of English
directives performed by native Japanese speakers. Unpublished paper, Department of English as a Second
Language, University of Hawai'i at Manoa, Honolulu.
Appendix
The appendix should be used for data collected (e.g. questionnaires, transcripts,...) and for tables and
graphs not included in the main text due to their subsidiary nature or to space constraints in the main text.
Assessment Scheme:
Objectives:
The aim of the project is to provide the students with an opportunity to further their intellectual and
personal development in the chosen field by undertaking a significant practical unit of activity. The
project can be defined as a scholarly inquiry into a problem or issues, involving a systematic approach to
gathering and analysis of information / data, leading to production of a structured report.
1) Cover Page: This should contain the title of the project proposal, to whom it is submitted, for which
degree, the name of the author, name of the supervisor, year of submission of the project work, name of
the University.
2) Acknowledgement: Various organizations and individuals who might have provided assistance /co-
operation during the process of carrying out the study.
3) Table of Content: Page-wise listing of the main contents in the report, i.e., different Chapters and its
main Sections along with their page numbers.
4) Body of the Report: The body of the report should have these four logical divisions
a) Introduction: This will cover the background, rationale/ need / justification, brief review of literature,
objectives, methodology (the area of the study, sample, type of study, tools for data collection, and
method of analysis), Limitations of the Study, and Chapter Planning.
b) Conceptual Framework / National and International Scenario: (relating to the topic of the Project).
c) Presentation of Data,Analysis and Findings:(using the tools and techniques mentioned in the
methodology).
d) Conclusion and Recommendations: In this section, the concluding observations based on the main
findings and suggestions are to be provided.
5) Bibliography or References: This section will include the list of books and articles which have been
used in the project work, and in writing a project report.
Step I : Selection of the topic for the project by taking following points into consideration:
Suitability of the topic.
Relevance of the topic
Time available at the disposal.
Feasibility of data collection within the given time limit.
Challenges involved in the data collection (time & cost involved in the data collection, possibility
of getting responses, etc.)
Step II : Finalisation of the Topic and preparation of Project Proposal in consultation with the Supervisor.
Step III : Collection of information and data relating to the topic and analysis of the same.
Step V : The following documents are to be attached with the Final Project Report.
1) Approval letter from the supervisor (Annexure-IA)
2) Student‟s declaration (Annexure-IB)
3) Certificate from the Competent Authority of the Organisation / Institution, if the student
undertakes the Project Work in any Organisation / Institution.
Objectives
A workshop is primarily an activity based academic event that is organized to provide the students a one
to one and hands on experience on any aspect of their learning. The communication in a workshop has to
be necessarily two way. The trainer has to make sure that the aspect covered are practically practiced by
the participants. The student will choose the option of workshop from amongst their concentration
electives. The evaluation will be done by Board of examiners comprising of the faculties.
Methodology
The methodology followed at the workshop could be based on any one or more of the following methods:
Case Study
Business Game
Simulation
Group Activity
Role Play
Business Planning
Quiz
Evaluation Scheme:
Attendance Active Multiple Choice Solving the case/ Total
Participation Questions/ Quiz Assignment/
Write up
10 30 30 30 100
Syllabus – Fifth Semester
Course Contents:
Module I
Preparation of DNA: genomic, Plasmid
Module II
Isolation of RNA
Module III
RFLP analysis
Module IV
Gel filtration
Module V
Preparation of Competent Cells
Module VI
Restriction Digestion and Ligation of DNA
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
ANIMAL BIOTECHNOLOGY LAB
Course Code: BTE2506 CreditUnits: 02
Course Contents:
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
PLANT BIOTECHNOLOGY LAB
Course Code: BTE2507 Credit Units: 02
Course Contents:
Module I
Sterilization of glasswares and equipments.
Preparation of cotton plugs and culture media
Preparation of stocks for culture media
Preparation of culture media
Module II
Preparation and sterilization of different explants
Inoculation of explants on culture media
Module III
Study of viability of seeds
Embryo culture
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
BIOINFORMATICSLAB
Course Code: BTE2508 Credit Units: 01
List of Experiments/Exercises
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
Note: Minor variation could be there depending on the examiner.
SUMMER INTERNSHIP EVALUATION-I
Course Code: BTE2535 Credit Units: 03
Methodology
The students will be sent to various industries and institutes where they will undergo short term training.
After the completion of the training the students will be required to submit project report which shall then
be evaluated by two internal examiners. The students will then have to appear for a Viva Voce
examination to be conducted by an external evaluator at the end of the semester.
Report Layout
The report should contain the following components:
Acknowledgements (optional)
Acknowledgment to any advisory or financial assistance received in the course of work may be given.
Abstract
A good"Abstract" should be straight to the point; not too descriptive but fully informative. First paragraph
should state what was accomplished with regard to the objectives. The abstract does not have to be an
entire summary of the project, but rather a concise summary of the scope and results of the project
Table of Contents
Titles and subtitles are to correspond exactly with those in the text.
Introduction
Here a brief introduction to the problem that is central to the project and an outline of the structure of the
rest of the report should be provided. The introduction should aim to catch the imagination of the reader,
so excessive details should be avoided.
Materials and Methods
This section should aim at experimental designs, materials used. Methodology should be mentioned in
details including modifications if any.
Note that in writing the various secions, all figures and tables should as far as possible be next to the
associated text, in the same orientation as the main text, numbered, and given appropriate titles or
captions. All major equations should also be numbered and unless it is really necessary never write in
“point” form.
Conclusion
A conclusion should be the final section in which the outcome of the work is mentioned briefly.
Future prospects
Appendices
The Appendix contains material which is of interest to the reader but not an integral part of the thesis and
any problem that have arisen that may be useful to document for future reference.
References / Bibliography
This should include papers and books referred to in the body of the report. These should be ordered
alphabetically on the author's surname. The titles of journals preferably should not be abbreviated; if they
are, abbreviations must comply with an internationally recognised system.
Examples
For research article
Voravuthikunchai SP, Lortheeranuwat A, Ninrprom T, Popaya W, Pongpaichit S, Supawita T. (2002)
Antibacterial activity of Thai medicinal plants against enterohaemorrhagic Escherichia coli O157: H7.
Clin Microbiol Infec, 8 (suppl 1): 116–117.
For book
Kowalski, M. (1976) Transduction of effectiveness in Rhizobium meliloti. SYMBIOTIC NITROGEN
FIXATION PLANTS (editor P.S. Nutman IBP), 7: 63-67
Execution of Research
Data Analysis
Analyse Quantitative/ Qualitative information
Control Quality
Draw Conclusions
Examination Scheme:
Project Report 50
Viva Voce 50
Total 100
Course Objective:
The course is designed to give a broad view of mammalian stem cells, reviewing where they are found in
the body, different types and how they are cultured. The topics will cover the basic biology of these stem
cells as well as bioengineering and application of these stem cells to potential treatments of human
diseases.
Course Contents:
Module I
Stem Cell biology; types; embryonic stem cell, Adult stem cell and potential benefits of stem cell
technology, Bone marrow transplants, Immunotherapy, Autoimmune Diseases and Promise of Stem Cell-
Based Therapies, Stem Cells and Diabetes, Stem Cells and heart Repair
Module II
Gene Therapy: Introduction, History and evolution of Gene therapy, optimal disease targets, Failures and
successes of gene therapy and future prospects; Gene Therapy and Immune System: Genetic
Immunization, Innate and Acquired Immune Response to Gene Therapy
Module III
Gene Delivery methods; Viral vectors: Adenoviral, Adeno-associated virus (AAV), Retroviral, Lentiviral,
Herpes Virus; Non-viral Vectors and Physical Methods & Combinatorial methods. Genetic perspectives
for Gene Therapy, Gene Therapy for Cancer and Vascular Disorders, Nervous System.
Module IV
Regulatory and Ethical Considerations of Cell and Gene Therapy, Assessing Human Stem Cell Safety,
Use of Genetically Modified Stem Cells in Experimental Gene Therapies.
Examination Scheme:
Text:
Stem cell biology and gene therapy, Booth C., Cell Biology International, Academic Press
Stem Cell and Gene-Based Therapy: Frontiers in Regenerative Medicine, Alexander Battler,
Jonathan Leo, Springer,
References:
Stem Cell Biology and Gene Therapy. Quesenberry PJ, Stein GS, eds. (£65.00.) Wiley, 1998.
Progress in gene therapy, Volume 2,Pioneering stem cell/gene therapy trials, Roger Bertolotti, Keiya
Ozawa and H. Kirk Hammond, VSP international science publishers
Stem Cells Handbook: Stewart Sell, Humana Press; Totowa NJ, USA; Oct. 2003,
Understanding Biotechnology by Aluízio Borém, Fabrício R. Santos, David E. Bowen, Prentice Hall
Cell Therapy: Stem Cell Transplantation, Gene Therapy, and Cellular Immunotherapy (Cancer:
Clinical Science in Practice) George Morstyn, William Sheridan, Cambridge University Press,
JAVA-I
Course Code: BTE2511 Credit Units: 02
Course Objective:
The objective is to introduce students to a modern programming language and help them gain sufficient
fluency to undertake research projects with a programming component; to lay the foundations for more
advanced study of object-oriented languages
Emphasis is on to understand the basic concepts of programming; to learn the syntax and semantics of
Java; to be able to use a program development environment
Course Contents:
Module I
Introduction to Java - Features, Inheritance, Strings, Packages, Interfaces; Multi- Threading, Applet
Programming: AWT- Components, Menus, Layout manager, etc., Event Handling,, Java Packages -
java.util, -java.io; exception handling,
Module II
Collection API - Arrays, Collection Interfaces, Concrete Collections, The Collections Framework,
Legacy Collections
Module III
Swing
Module IV
JDBC
Introduction to Client Server Application
Java Drivers
java.sql Package
Installing and setting up JDBC
Basic JDBC Programming concepts
Populating a database
Executing Queries
Scrollable and Updateable Result Sets
Examination Scheme:
TERM PAPER
Course Code: BTE2531 Credit Units: 02
METHODOLOGY
A term (or research) paper is primarily a record of intelligent reading in several sources on a particular
subject.
The students will choose the topic at the beginning of the session in consultation with the faculty
assigned. The progress of the paper will be monitored regularly by the faculty. At the end of the semester
the detailed paper on the topic will be submitted to the faculty assigned. The evaluation will be done by
Board of examiners comprising of the faculties.
1. Choosing a Subject
The subject chosen should not be too general.
Discussion
The discussion section either follows the results or may alternatively be integrated in the results section.
The section should consist of a discussion of the results of the study focusing on the question posed in the
research paper.
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded.
There are a number of key components which should not be omitted. These include:
i) summary of question posed
j) summary of findings
k) summary of main limitations of the study at hand
l) details of possibilities for related future research
References
From the very beginning of a research project, you should be careful to note all details of articles
gathered.
The bibliography should contain ALL references included in the paper. References not included in the
text in any form should NOT be included in the bibliography.
The key to a good bibliography is consistency. Choose a particular convention and stick to this.
Bibliographical conventions
Monographs
Crystal, D. (2001), Language and the internet. Cambridge: Cambridge University Press.
Edited Volumes
Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second
language. Berlin/ NY: Mouton de Gruyter.
[(eds.) is used when there is more than one editor; and (ed.) where there is only one editor. In German the
abbreviation used is (Hrsg.) for Herausgeber].
Edited Articles
Schmidt, R./Shimura, A./Wang, Z./Jeong, H. (1996), Suggestions to buy: Television commercials from
the U.S., Japan, China, and Korea. In: Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures.
Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter: 285-316.
Journal Articles
McQuarrie, E.F./Mick, D.G. (1992), On resonance: A critical pluralistic inquiry into advertising rhetoric.
Journal of consumer research 19, 180-197.
Electronic Book
Chandler, D. (1994), Semiotics for beginners [HTML document]. Retrieved [5.10.'01] from the World
Wide Web, http://www.aber.ac.uk/media/Documents/S4B/.
Other Websites
Verterhus, S.A. (n.y.), Anglicisms in German car advertising. The problem of gender assignment [HTML
document]. Retrieved [13.10.'01] from the World Wide Web, http://olaf.hiof.no/~sverrev/eng.html.
Unpublished Papers
Takahashi, S./DuFon, M.A. (1989), Cross-linguistic influence in indirectness: The case of English
directives performed by native Japanese speakers. Unpublished paper, Department of English as a Second
Language, University of Hawai'i at Manoa, Honolulu.
Appendix
The appendix should be used for data collected (e.g. questionnaires, transcripts,...) and for tables and
graphs not included in the main text due to their subsidiary nature or to space constraints in the main text.
Assessment Scheme:
Objectives:
The aim of the project is to provide the students with an opportunity to further their intellectual and
personal development in the chosen field by undertaking a significant practical unit of activity. The
project can be defined as a scholarly inquiry into a problem or issues, involving a systematic approach to
gathering and analysis of information / data, leading to production of a structured report.
1) Cover Page: This should contain the title of the project proposal, to whom it is submitted, for which
degree, the name of the author, name of the supervisor, year of submission of the project work, name of
the University.
2) Acknowledgement: Various organizations and individuals who might have provided assistance /co-
operation during the process of carrying out the study.
3) Table of Content: Page-wise listing of the main contents in the report, i.e., different Chapters and its
main Sections along with their page numbers.
4) Body of the Report: The body of the report should have these four logical divisions
a) Introduction: This will cover the background, rationale/ need / justification, brief review of literature,
objectives, methodology (the area of the study, sample, type of study, tools for data collection, and
method of analysis), Limitations of the Study, and Chapter Planning.
b) Conceptual Framework / National and International Scenario: (relating to the topic of the Project).
c) Presentation of Data,Analysis and Findings:(using the tools and techniques mentioned in the
methodology).
d) Conclusion and Recommendations: In this section, the concluding observations based on the main
findings and suggestions are to be provided.
5) Bibliography or References: This section will include the list of books and articles which have been
used in the project work, and in writing a project report.
Step I : Selection of the topic for the project by taking following points into consideration:
Suitability of the topic.
Relevance of the topic
Time available at the disposal.
Feasibility of data collection within the given time limit.
Challenges involved in the data collection (time & cost involved in the data collection, possibility
of getting responses, etc.)
Step II : Finalisation of the Topic and preparation of Project Proposal in consultation with the Supervisor.
Step III : Collection of information and data relating to the topic and analysis of the same.
Step V : The following documents are to be attached with the Final Project Report.
1) Approval letter from the supervisor (Annexure-IA)
2) Student‟s declaration (Annexure-IB)
3) Certificate from the Competent Authority of the Organisation / Institution, if the student
undertakes the Project Work in any Organisation / Institution.
WORKSHOP / CERTIFICATION
Course Code: BTE2533 Credit Units: 02
Objectives
A workshop is primarily an activity based academic event that is organized to provide the students a one
to one and hands on experience on any aspect of their learning. The communication in a workshop has to
be necessarily two way. The trainer has to make sure that the aspect covered are practically practiced by
the participants. The student will choose the option of workshop from amongst their concentration
electives. The evaluation will be done by Board of examiners comprising of the faculties.
Methodology
The methodology followed at the workshop could be based on any one or more of the following methods:
Case Study
Business Game
Simulation
Group Activity
Role Play
Business Planning
Quiz
Evaluation Scheme:
Attendance Active Multiple Choice Solving the case/ Total
Participation Questions/ Quiz Assignment/
Write up
10 30 30 30 100
Course Objective:
A complete understanding of molecular techniques can be obtained through the course. The successful
application of biotechnology largely depends on these advanced molecular techniques.
Course Contents:
Module I: Enzymes used in RDT
Restriction endonuclease, methyltransferase, ligase, polymerase, kinase, phosphatase, nuclease,
transferase, reverse transcriptase.
Examination Scheme:
Course Objective:
The objective of the course is to apply the principles of biochemical engineering in large scale cultivation
of microorganism for production of important products.
Course Contents:
Module I
Advantage of bioprocess over chemical process. Basic principle in bioprocess technology. Media
formulation, Cell culture techniques; Inoculum development and aseptic transfers. Different types of
pumps, valves, and line materials, piping conventions etc. used in Biochemical Process
Module II
Process technology for the production of primary metabolites, eg. biomass, ethanol, acetone-butanol,
citric acid, amino acids, polysaccharides and plastics.
Ethanol: production by batch, continuous and cell recycle adopted by various technologies practiced in
Indian distilleries using molasses and grains. Computation of fermentation efficiency, distillation
efficiency and overall efficiency of ethanol production, recovery, uses, glucose effect etc. Power alcohol
– definition, uses, merits and demerits of various technologies for its production.
Biomass: Bakers and distillers yeast production using various raw materials, “bios” factors for growth,
Crabtree effect, harvesting, different forms and uses.
What are mushroom, different forms of common mushroom production from agro based raw materials
and uses. Biofertilizers, biocompost and biopesticides
Module III
Production of secondary metabolites – penicillin, cephalosporins, streptomycin, tetracycline etc.
Metabolites from plant and animal cell culture
Penicillin: Classification, various penicillin as precursor and „R‟ – side chain, penicillinase, 6-APA,
penicillin production, harvest and recovery, uses of various forms etc.
Streptomycin: chemical structure, production, harvest and recovery, use by-product of streptomycin
fermentation etc.
Tetracycline: chemical structure, production, harvest and recovery, use by-product of tetracycline
fermentation etc.
Module IV
Microbial production of industrial enzymes – glucose isomerase, penicillin acylase, cellulase, amylase,
lipase, protease etc.
Examination Scheme:
Course Objective:
Role of antibody engineering in biomedical applications and the importance of immuno genetics in
disease processes, tissue transplantation and immune regulation are some of the areas of attributes of this
course which can help the students to understand the biotechnology related to human kind.
Course Contents:
Module I: Introduction
Phylogeny of Immune System, Innate and acquired immunity, clonal nature of Immune Response.
Organization and structure of lymphoid organs Nature and Biology of antigens and super antigens
Antibody structure and function; Types of immunity- innate, acquired, active and passive.
Examination Scheme:
Text:
Basic Immunology, A.K. Abbas and A.H. Lichtman, Saunders W.B. Company
Basic Immunology, A.K. Abbas and A.H. Lichtman, Saunders W.B. Company
References:
Fundamentals of Immunology, W. Paul, Lippincott Williams and Wilkins
Immunology, W.L. Anderson, Fence Creek Publishing (Blackwell).
Immunology: A Short Course, E. Benjamin, R. Coico and G. Sunshine, Wiley-Leiss Inc.
Immunology, Roitt, Mosby – Yearbook Inc.
Kuby Immunology, R.A. Goldsby, T.J. Kindt, and B.A. Osborne, Free
RECOMBINANT DNA TECHNOLOGY LAB
Course Code: BTE2605 Credit Units: 02
Course Objective:
The laboratory experiments in Recombinant DNA Technology would certainly help to comprehend the
theoretical aspects of the subject.
Course Contents:
Module I
Study of cloning (GFP CLONING)
Module II
Study of PCR
Module III
Study of Southern hybridiosation
Module IV
Study of RAPD
Module V
Site directed mutagenesis
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
BIOPROCESS TECHNOLOGY LAB
Course Code: BTE2606 Credit Units: 02
Course Contents:
Module I
Isolation of industrially important micro organisms for microbial processes.
Module II
Determination of Thermal Death Point and Thermal death time of micro organisms for design of a
sterilizer
Module III
Determination of growth curve of a supplied micro organism and also determine substrate degradation
profile and to compute specific growth rate and growth yield from the data obtained.
Module IV
Comparative studies of ethanol production using different substrates.
Module V
Production of single cell protein
Module VI
Production and estimation of alkaline protease
Module VII
Sauer Krant fermentation
Module VIII
Use of alginate for cell immobilization
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
IMMUNOLOGY AND IMMUNOTECHNOLOGY LAB
Course Code: BTE2607 Credit Units: 01
Course Contents:
Module I
Blood film preparation and identification of cells.
Module II
Identification of blood group.
Module III
Isolation of serum.
Module IV
Lymphoid organs and their microscopic organization.
Module V
WIDAL Test
Module VI
Radial Immuno Diffusion Test
Module VII
Ouchterlony Double diffusion Test
Module IX
Purification of lgG through affinity chromatography
Module X
Immunohistochemistry
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
.
PHARMACEUTICAL BIOTECHNOLOGY
Course Code: BTE2608 Credit Units: 02
Course Objective:
The main objectives are to cover representative pharmaceutical dosage forms, and general issues of
formulation, production, quality requirements, validation and uses and to gain an understanding of the
challenges associated with quality pharmaceutical manufacturing
Course Contents:
Module I
Introduction to Physical Pharmaceutics - Metrology and Calculations,
Module II
Molecular structure, properties and States of Matter, Solutions, Phase Equilibra, Micromeritic and Powder
Rheology, Surface and Interfacial Phenomena, Dispersion Systems, Diffusion & Dissolution, Kinetics
and
drug stability, Viscosity & Rheology
Module III
Polymer Science and Applications, Formulations and Development, Packaging
Module IV
Introduction to Industrial Processing, Transport Phenomena (Fluid Flow, Heat Transfer and Mass
Transfer)
Module V
Particulate Technology (Particle Size, Size reduction, Size Separation, Powder Flow and Compaction),
Unit Operations (Mixing, Evaporation, Filtration, Centrifugation, Extraction, Distillation, and Drying)
Module VI
Materials of Pharmaceutical Plant Construction, Good Manufacturing Practice (GMP‟s) Guidelines
Examination Scheme:
Text:
Bentley's Pharmaceutics by E A Rawlins
Pharmaceutical Sciences by Remington
References:
Physical Pharmacy by Alfred Martin.
Cooper and Gunn's Tutorial Pharmacy
MOLECULAR MODELLING
Course Code: BTE2609 Credit Units: 02
Course Objective:
The students should be able to understand and work on the following topics: various levels of structural
organizations in bio-molecules; representation of the 2D and 3D structures: coordinate systems &
modeling; bioinformatics approaches for structure analysis and structure predictions; conformations &
analysis of macromolecules.
Course Contents
Module I
Internal and external co-ordinate system; Generation of co-ordinates of biopolymers in Cartesian and
cylindrical polar co-ordinate System.
Module V
Methods to predict three dimensional structures of nucleic acids, rRNA, tRNA, and proteins
Module VI
Molecular mechanics & dynamics of oligopeptides, proteins, nucleotides and small molecules;
Conformational Searches; Simulation of molecular mechanics and dynamics; Simulations of Free Energy
changes; Electrostatics of Biomolecules
Examination Scheme:
Components CT Attendance Assignment/ EE
Project/Seminar/Quiz
Weightage (%) 15 5 10 70
Course Objective:
This course will enable the students to gain knowledge about a relatively newer area of science. The
course is designed to model the different technical properties, applications, besides the closely related
aspects of artificial neural networks.
Course Contents:
Module I
Historical background, Why is learning hard?
Module II
Memorization, generalization and function approximation, Linear Associators, Perceptrons and Capacity,
Multilayer neural networks, Maximum Likelihood and Gradient Descent learning, Stochastic gradient
descent for supervised learning.
Module III
The back propagation algorithm, Aspects of Learning Theory and Generalization, Bias vs. variance,
Overtraining, pruning and regularization, VC dimension and how much data is enough?.
Module IV
Neural networks and analog VLSI, Selected Applications.
Examination Scheme:
Text:
Neural Networks: A Comprehensive Foundation by S. Haykin, Prentice Hall.
References:
Neutral Networks for Pattern Recognition by C. Bishop, Oxford University Press.
JAVA-II
Course Code: BTE2611 Credit Units: 02
Course Objective
The objective is to introduce students to a serverside programming language and help them gain sufficient
fluency to undertake research projects with a programming component; to lay the foundations for study of
web technologies and different tools used for the same.
Emphasis is on to understand the basic concepts of web programming; to learn the syntax and semantics
of Servlet and JSP; to be able to use a server side program development environment
Course Contents
Module I
HTML and JavaScript, Creating and processing HTML forms
Module II
Java Servlets
Introduction to Server Side Application Development
Basics of Servlet Programming
Web Container
Session Tracking
Servlet Context
Examination Scheme:
METHODOLOGY
A term (or research) paper is primarily a record of intelligent reading in several sources on a particular
subject.
The students will choose the topic at the beginning of the session in consultation with the faculty
assigned. The progress of the paper will be monitored regularly by the faculty. At the end of the semester
the detailed paper on the topic will be submitted to the faculty assigned. The evaluation will be done by
Board of examiners comprising of the faculties.
1. Choosing a Subject
The subject chosen should not be too general.
Discussion
The discussion section either follows the results or may alternatively be integrated in the results section.
The section should consist of a discussion of the results of the study focusing on the question posed in the
research paper.
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded.
There are a number of key components which should not be omitted. These include:
m) summary of question posed
n) summary of findings
o) summary of main limitations of the study at hand
p) details of possibilities for related future research
References
From the very beginning of a research project, you should be careful to note all details of articles
gathered.
The bibliography should contain ALL references included in the paper. References not included in the
text in any form should NOT be included in the bibliography.
The key to a good bibliography is consistency. Choose a particular convention and stick to this.
Bibliographical conventions
Monographs
Crystal, D. (2001), Language and the internet. Cambridge: Cambridge University Press.
Edited Volumes
Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second
language. Berlin/ NY: Mouton de Gruyter.
[(eds.) is used when there is more than one editor; and (ed.) where there is only one editor. In German the
abbreviation used is (Hrsg.) for Herausgeber].
Edited Articles
Schmidt, R./Shimura, A./Wang, Z./Jeong, H. (1996), Suggestions to buy: Television commercials from
the U.S., Japan, China, and Korea. In: Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures.
Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter: 285-316.
Journal Articles
McQuarrie, E.F./Mick, D.G. (1992), On resonance: A critical pluralistic inquiry into advertising rhetoric.
Journal of consumer research 19, 180-197.
Electronic Book
Chandler, D. (1994), Semiotics for beginners [HTML document]. Retrieved [5.10.'01] from the World
Wide Web, http://www.aber.ac.uk/media/Documents/S4B/.
Other Websites
Verterhus, S.A. (n.y.), Anglicisms in German car advertising. The problem of gender assignment [HTML
document]. Retrieved [13.10.'01] from the World Wide Web, http://olaf.hiof.no/~sverrev/eng.html.
Unpublished Papers
Takahashi, S./DuFon, M.A. (1989), Cross-linguistic influence in indirectness: The case of English
directives performed by native Japanese speakers. Unpublished paper, Department of English as a Second
Language, University of Hawai'i at Manoa, Honolulu.
Appendix
The appendix should be used for data collected (e.g. questionnaires, transcripts,...) and for tables and
graphs not included in the main text due to their subsidiary nature or to space constraints in the main text.
Assessment Scheme:
Objectives:
The aim of the project is to provide the students with an opportunity to further their intellectual and
personal development in the chosen field by undertaking a significant practical unit of activity. The
project can be defined as a scholarly inquiry into a problem or issues, involving a systematic approach to
gathering and analysis of information / data, leading to production of a structured report.
1) Cover Page: This should contain the title of the project proposal, to whom it is submitted, for which
degree, the name of the author, name of the supervisor, year of submission of the project work, name of
the University.
2) Acknowledgement: Various organizations and individuals who might have provided assistance /co-
operation during the process of carrying out the study.
3) Table of Content: Page-wise listing of the main contents in the report, i.e., different Chapters and its
main Sections along with their page numbers.
4) Body of the Report: The body of the report should have these four logical divisions
a) Introduction: This will cover the background, rationale/ need / justification, brief review of literature,
objectives, methodology (the area of the study, sample, type of study, tools for data collection, and
method of analysis), Limitations of the Study, and Chapter Planning.
b) Conceptual Framework / National and International Scenario: (relating to the topic of the Project).
c) Presentation of Data,Analysis and Findings:(using the tools and techniques mentioned in the
methodology).
d) Conclusion and Recommendations: In this section, the concluding observations based on the main
findings and suggestions are to be provided.
5) Bibliography or References: This section will include the list of books and articles which have been
used in the project work, and in writing a project report.
Step I : Selection of the topic for the project by taking following points into consideration:
Suitability of the topic.
Relevance of the topic
Time available at the disposal.
Feasibility of data collection within the given time limit.
Challenges involved in the data collection (time & cost involved in the data collection, possibility
of getting responses, etc.)
Step II : Finalisation of the Topic and preparation of Project Proposal in consultation with the Supervisor.
Step III : Collection of information and data relating to the topic and analysis of the same.
Step V : The following documents are to be attached with the Final Project Report.
1) Approval letter from the supervisor (Annexure-IA)
2) Student‟s declaration (Annexure-IB)
3) Certificate from the Competent Authority of the Organisation / Institution, if the student
undertakes the Project Work in any Organisation / Institution.
Objectives
A workshop is primarily an activity based academic event that is organized to provide the students a one
to one and hands on experience on any aspect of their learning. The communication in a workshop has to
be necessarily two way. The trainer has to make sure that the aspect covered are practically practiced by
the participants. The student will choose the option of workshop from amongst their concentration
electives. The evaluation will be done by Board of examiners comprising of the faculties.
Methodology
The methodology followed at the workshop could be based on any one or more of the following methods:
Case Study
Business Game
Simulation
Group Activity
Role Play
Business Planning
Quiz
Evaluation Scheme:
Attendance Active Multiple Choice Solving the case/ Total
Participation Questions/ Quiz Assignment/
Write up
10 30 30 30 100
Syllabus – Seventh Semester
IPR, BIOSAFETY & BIOETHICS
Course Code: BTE2702 Credit Units: 02
Course Objective
The aim of this course is to develop the understanding of relevance, business Impact and protection of
Intellectual Property along with the types of Intellectual Property Rights: Patents, Trademarks,
Copyrights, Industrial Designs, Geographical Indications and International Conventions, Biosafety and
Bioethics
Course Contents
Module V
Protection of Traditional Knowledge- Objective, Concept of Traditional Knowledge, Holders, Issues
concerning, Bio-Prospecting and Bio-Piracy, Alternative ways, Protectability, need for a Sui-Generis
regime, Traditional Knowledge on the International Arena, at WTO, at National level, Traditional
Knowledge Digital Library.
Module VI
Biosafety and Bioethics Management-Key to environmentally responsible use of biotechnology.
Cartagena Protocol on Biosafety, Ethical implications of Biotechnological products and techniques.
Examination Scheme:
Text
Intellectual Property Rights by Birgitte Anderson, Edward Elgar Publishing
Intellectual Property Rights and the Life Science Industries by Graham Dutfield, Ashgate Publishing
References
WIPO Intellectual Property Handbook
Intellectual Property by William Rodelph Cornish, David Clewelyn
Globalising Intellectual Property Rights by Duncan Matthews
Journals and Current magazines
RESEARCH METHODOLOGY AND REPORT WRITING
Course Code: BTE2703 Credit Units: 02
Course Objective
To develop understanding of information and library science research issues in the domain of
bioinformatics through review of journal articles, invited talks, and critical group discussions of methods.
The main objectives for this course are to develop: familiarity with information and library science-
oriented problems in the biomedical sciences, an understanding of research methods in the biomedical
domain, critical thinking and evaluation skills and presentation and summarization skills.
Course Contents
Module I
Introduction: Science, Scientific Field and Biological research. Role of a researcher in different stages of
a project, Routes to research funding (academic and commercial)
Module II
Research – Definition – Importance and Meaning of research – Characteristics of research – Types of
Research – Steps in research – Identification, Selection and formulation of research problem – Research
questions – Research design – Formulation of Hypothesis – Review of Literature.
Module IV
Type of Articles (review, letters etc). Scientific paper format (Abstract, Introduction, Materials and
Methods, Results, Discussion). Writing, evaluating, presenting and publishing the results of scientific
research in the academic press (journals, conferences etc). Choosing the appropriate journal (Sources,
Information, Instructions to authors, peer review system, journal evaluation)
Module V
Case studies of areas of current research. Formulating a research plan and its presentation
Examination Scheme:
Text:
Statistical Methods By S.P. Gupta
References:
Research Methodology Methods and Techniques by C.R. Kothari
Statistics(Theory and Practice) by B.N. Gupta
Research Methodology Methods and statistical Techniques by Santosh Gupta
Scientific journals and magazines
GENOMICS AND PROTEOMICS LAB
Course Code: BTE2704 Credit Units: 02
Course Contents:
Module I
Three dimensional Structures – In silico study – large molecular complexes RNA polymerase II,
ribosome, unstructured proteins
Module II
DNA sequencing methods
Module III
Gene finding tools and Genome annotation
Module IV
Comparison of two given genomes
Module V
Analysis of 2D – IEF data
Module VI
Microarray and Microarray data analysis
Module VII
Inference of protein function from structure
Module VIII
Inference of protein function and structure
Module IX
Two-hybrid methods
Examination Scheme:
IA EE
Class Test Mid Term Attendance Major Minor Practical Viva
(Practical Viva Experiment Experiment/Spotting Record
Based)
15 10 05 35 15 10 10
SUMMER INTERNSHIP EVALUATION-II
Course Code: BTE2735 Credit Units: 03
Methodology
The students will be sent to various industries and institutes where they will undergo short term training.
After the completion of the training the students will be required to submit project report which shall then
be evaluated by two internal examiners. The students will then have to appear for a Viva Voce
examination to be conducted by an external evaluator at the end of the semester.
Report Layout
The report should contain the following components:
Acknowledgements (optional)
Acknowledgment to any advisory or financial assistance received in the course of work may be given.
Abstract
A good"Abstract" should be straight to the point; not too descriptive but fully informative. First paragraph
should state what was accomplished with regard to the objectives. The abstract does not have to be an
entire summary of the project, but rather a concise summary of the scope and results of the project
Table of Contents
Titles and subtitles are to correspond exactly with those in the text.
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Introduction
Here a brief introduction to the problem that is central to the project and an outline of the structure of the
rest of the report should be provided. The introduction should aim to catch the imagination of the reader,
so excessive details should be avoided.
Note that in writing the various secions, all figures and tables should as far as possible be next to the
associated text, in the same orientation as the main text, numbered, and given appropriate titles or
captions. All major equations should also be numbered and unless it is really necessary never write in
“point” form.
Conclusion
A conclusion should be the final section in which the outcome of the work is mentioned briefly.
Future prospects
Appendices
The Appendix contains material which is of interest to the reader but not an integral part of the thesis and
any problem that have arisen that may be useful to document for future reference.
References / Bibliography
This should include papers and books referred to in the body of the report. These should be ordered
alphabetically on the author's surname. The titles of journals preferably should not be abbreviated; if they
are, abbreviations must comply with an internationally recognised system.
Examples
For research article
Voravuthikunchai SP, Lortheeranuwat A, Ninrprom T, Popaya W, Pongpaichit S, Supawita T. (2002)
Antibacterial activity of Thai medicinal plants against enterohaemorrhagic Escherichia coli O157: H7.
Clin Microbiol Infec, 8 (suppl 1): 116–117.
For book
Kowalski, M. (1976) Transduction of effectiveness in Rhizobium meliloti. SYMBIOTIC NITROGEN
FIXATION PLANTS (editor P.S. Nutman IBP), 7: 63-67
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Range of Research Methods used to obtain information
Execution of Research
Data Analysis
Analyse Quantitative/ Qualitative information
Control Quality
Draw Conclusions
Examination Scheme:
Project Report 50
Viva Voce 50
Total 100
TERM PAPER
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Course Code: BTE2731 Credit Units: 02
METHODOLOGY
A term (or research) paper is primarily a record of intelligent reading in several sources on a particular
subject.
The students will choose the topic at the beginning of the session in consultation with the faculty
assigned. The progress of the paper will be monitored regularly by the faculty. At the end of the semester
the detailed paper on the topic will be submitted to the faculty assigned. The evaluation will be done by
Board of examiners comprising of the faculties.
1. Choosing a Subject
The subject chosen should not be too general.
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6. Editing & Preparing the final Paper
y) Before writing a term paper, you should ensure you have a question which you attempt to answer in
your paper. This question should be kept in mind throughout the paper. Include only information/
details/ analyses of relevance to the question at hand. Sometimes, the relevance of a particular section
may be clear to you but not to your readers. To avoid this, ensure you briefly explain the relevance of
every section.
z) Read the paper to ensure that the language is not awkward, and that it "flows" properly.
aa) Check for proper spelling, phrasing and sentence construction.
bb) Check for proper form on footnotes, quotes, and punctuation.
cc) Check to see that quotations serve one of the following purposes:
(xiii) Show evidence of what an author has said.
(xiv) Avoid misrepresentation through restatement.
(xv) Save unnecessary writing when ideas have been well expressed by the original author.
dd) Check for proper form on tables and graphs. Be certain that any table or graph is self-explanatory.
Discussion
The discussion section either follows the results or may alternatively be integrated in the results section.
The section should consist of a discussion of the results of the study focusing on the question posed in the
research paper.
Conclusion
The conclusion is often thought of as the easiest part of the paper but should by no means be disregarded.
There are a number of key components which should not be omitted. These include:
q) summary of question posed
r) summary of findings
s) summary of main limitations of the study at hand
t) details of possibilities for related future research
References
From the very beginning of a research project, you should be careful to note all details of articles
gathered.
The bibliography should contain ALL references included in the paper. References not included in the
text in any form should NOT be included in the bibliography.
The key to a good bibliography is consistency. Choose a particular convention and stick to this.
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Bibliographical conventions
Monographs
Crystal, D. (2001), Language and the internet. Cambridge: Cambridge University Press.
Edited Volumes
Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures. Challenges to communication in a second
language. Berlin/ NY: Mouton de Gruyter.
[(eds.) is used when there is more than one editor; and (ed.) where there is only one editor. In German the
abbreviation used is (Hrsg.) for Herausgeber].
Edited Articles
Schmidt, R./Shimura, A./Wang, Z./Jeong, H. (1996), Suggestions to buy: Television commercials from
the U.S., Japan, China, and Korea. In: Gass, S./Neu, J. (eds.) (1996), Speech acts across cultures.
Challenges to communication in a second language. Berlin/ NY: Mouton de Gruyter: 285-316.
Journal Articles
McQuarrie, E.F./Mick, D.G. (1992), On resonance: A critical pluralistic inquiry into advertising rhetoric.
Journal of consumer research 19, 180-197.
Electronic Book
Chandler, D. (1994), Semiotics for beginners [HTML document]. Retrieved [5.10.'01] from the World
Wide Web, http://www.aber.ac.uk/media/Documents/S4B/.
Other Websites
Verterhus, S.A. (n.y.), Anglicisms in German car advertising. The problem of gender assignment [HTML
document]. Retrieved [13.10.'01] from the World Wide Web, http://olaf.hiof.no/~sverrev/eng.html.
Unpublished Papers
Takahashi, S./DuFon, M.A. (1989), Cross-linguistic influence in indirectness: The case of English
directives performed by native Japanese speakers. Unpublished paper, Department of English as a Second
Language, University of Hawai'i at Manoa, Honolulu.
Appendix
The appendix should be used for data collected (e.g. questionnaires, transcripts,...) and for tables and
graphs not included in the main text due to their subsidiary nature or to space constraints in the main text.
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Assessment Scheme:
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PROJECT
Course Code: BTE2732 Credit Units: 02
Objectives:
The aim of the project is to provide the students with an opportunity to further their intellectual and
personal development in the chosen field by undertaking a significant practical unit of activity. The
project can be defined as a scholarly inquiry into a problem or issues, involving a systematic approach to
gathering and analysis of information / data, leading to production of a structured report.
1) Cover Page: This should contain the title of the project proposal, to whom it is submitted, for which
degree, the name of the author, name of the supervisor, year of submission of the project work, name of
the University.
2) Acknowledgement: Various organizations and individuals who might have provided assistance /co-
operation during the process of carrying out the study.
3) Table of Content: Page-wise listing of the main contents in the report, i.e., different Chapters and its
main Sections along with their page numbers.
4) Body of the Report: The body of the report should have these four logical divisions
a) Introduction: This will cover the background, rationale/ need / justification, brief review of literature,
objectives, methodology (the area of the study, sample, type of study, tools for data collection, and
method of analysis), Limitations of the Study, and Chapter Planning.
b) Conceptual Framework / National and International Scenario: (relating to the topic of the Project).
c) Presentation of Data,Analysis and Findings:(using the tools and techniques mentioned in the
methodology).
d) Conclusion and Recommendations: In this section, the concluding observations based on the main
findings and suggestions are to be provided.
5) Bibliography or References: This section will include the list of books and articles which have been
used in the project work, and in writing a project report.
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The Steps of a Project Report
Step I : Selection of the topic for the project by taking following points into consideration:
Suitability of the topic.
Relevance of the topic
Time available at the disposal.
Feasibility of data collection within the given time limit.
Challenges involved in the data collection (time & cost involved in the data collection, possibility
of getting responses, etc.)
Step II : Finalisation of the Topic and preparation of Project Proposal in consultation with the Supervisor.
Step III : Collection of information and data relating to the topic and analysis of the same.
Step IV: Writing the report dividing it into suitable chapters, viz.,
Chapter 1: Introduction,
Chapter 2: Conceptual Framework / National & International Scenario,
Chapter 3: Analysis & Findings
Chapter 4: Conclusion and Recommendations.
Step V: The following documents are to be attached with the Final Project Report.
1) Approval letter from the supervisor (Annexure-IA)
2) Student‟s declaration (Annexure-IB)
3) Certificate from the Competent Authority of the Organisation / Institution, if the student
undertakes the Project Work in any Organisation / Institution.
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WORKSHOP / CERTIFICATION
Course Code: BTE2733 Credit Units: 02
Objectives
A workshop is primarily an activity based academic event that is organized to provide the students a one
to one and hands on experience on any aspect of their learning. The communication in a workshop has to
be necessarily two way. The trainer has to make sure that the aspect covered are practically practiced by
the participants. The student will choose the option of workshop from amongst their concentration
electives. The evaluation will be done by Board of examiners comprising of the faculties.
Methodology
The methodology followed at the workshop could be based on any one or more of the following methods:
Case Study
Business Game
Simulation
Group Activity
Role Play
Business Planning
Quiz
Evaluation Scheme:
Attendance Active Multiple Choice Solving the case/ Total
Participation Questions/ Quiz Assignment/
Write up
10 30 30 30 100
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Syllabus – Eighth Semester
PROJECT/ DISSERTATION
Course Code: BTE2837 Credit Units: 17
Course Objective:
The students are expected to utilize their scheduled periods by undertaking the project that would be
completed during the semester
Every student shall undertake a major Project. The major Project shall be undertaken in some
biotechnology industry or laboratory of repute. Each student shall be assigned to a faculty who shall
continuously monitor the progress of the Project in the concerned laboratory or industry. The faculty, in
consultation with the concerned scientist of the industry/laboratory, shall decide the topic of the project.
At the conclusion of the project the student shall submit a seminar and a dissertation. The dissertation
shall be evaluated by the internal faculty/examiner. The student then shall have to appear for the viva
voce examination.
Research is genuine exploration of the unknown that leads to new knowledge which often warrants
publication. But whether or not the results of a research project are publishable, the project should be
communicated in the form of a research report written by the student.
Sufficient time should be allowed for satisfactory completion of reports, taking into account that initial
drafts should be critiqued by the faculty guide and corrected by the student at each stage.
The File is the principal means by which the work carried out will be assessed and therefore great care
should be taken in its preparation.
Report Layout
The report should contain the following components:
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Acknowledgements (optional)
Acknowledgment to any advisory or financial assistance received in the course of work may be given.
Abstract
A good"Abstract" should be straight to the point; not too descriptive but fully informative. First paragraph
should state what was accomplished with regard to the objectives. The abstract does not have to be an
entire summary of the project, but rather a concise summary of the scope and results of the project
Table of Contents
Titles and subtitles are to correspond exactly with those in the text.
Introduction
Here a brief introduction to the problem that is central to the project and an outline of the structure of the
rest of the report should be provided. The introduction should aim to catch the imagination of the reader,
so excessive details should be avoided.
Note that in writing the various secions, all figures and tables should as far as possible be next to the
associated text, in the same orientation as the main text, numbered, and given appropriate titles or
captions. All major equations should also be numbered and unless it is really necessary never write in
“point” form.
Conclusion
A conclusion should be the final section in which the outcome of the work is mentioned briefly.
Future prospects
Appendices
The Appendix contains material which is of interest to the reader but not an integral part of the thesis and
any problem that have arisen that may be useful to document for future reference.
References / Bibliography
This should include papers and books referred to in the body of the report. These should be ordered
alphabetically on the author's surname. The titles of journals preferably should not be abbreviated; if they
are, abbreviations must comply with an internationally recognised system.
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Examples
Execution of Research
Data Analysis
Analyse Quantitative/ Qualitative information
Control Quality
Draw Conclusions
Examination Scheme:
Dissertation: 100
Viva Voce: 100
Total: 200
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