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BI
OLOGY
nd
Cl
ass:2 y
ear Chapt
erNo.
20

1.Acent ralrol
ef orchromosomesi nher edi tywasf irstsuggest edi n1900,by:
a)Karlcorrens b)Gr eoger mendl e c) Wal t er d)Wal ther
Sutton fl
eming
2.Thenumberofchr omosomesi nmosqui toi s:
a)3 b)6 c) 9 d)12
3.Thenumberofchr omosomesi nhoney beei s:
a)8 b)16 c) 32 d)64
4.Thenumberofchr omosomesi ncor ni s:
a)5 b)10 c) 15 d)20
5.Thenumberofchr omosomesi nsugar canei s:
a)80 b)40 c) 20 d)10
6.Thenumberofchr omosomesi nf rogi s:
a)52 b)26 c) 13 d)7
7.Thenumberofchr omosomesi nmousei s:
a)10 b)20 c) 40 d)80
8.Asequenceoft hr
eenucl eoti
desi nmRNAi scal led:
a)Code b)Codon c) Ant icodon d)None
9.Atraitdeterminedbyageneont heX- chr omosomei ssaidt obe:
a)Autosomal b)Pseudoaut osomal c) Sex- linked d)Bot ha&b
10.
Thenumberofnucl eoti
desi nt heDNAoft ypi calhumanchr omosomei sabout :
a)10mi ll
ion b)40mi ll
ion c) 80mi ll
ion d)140mi ll
ion
11.
Adenineandguani near ecal l
ed:
a)Puri
nes b)Py rimi dines c) Bot ha&b d)None
12.
Aminoaci dar eactivat
edwhent heyr eactwi thATPi nthepr esenceofact i
vati
ngenz yme:
a)Aminoacy ler
RNAs b)Ami noacy l
etRNAs c) Ami noacy le d)None
ynt
het ase ynthet ase mRNA
synthet ase
13.
Successi veami noacidsbear ingt RNAswi l
lbi ndat :
a)Asite b)Bsi t
e c) Csi t e d)Dsi te
14.
Duringt r
anslationtheempt ytRNAswi llexi tther ibosomeat :
a)Csite b)Dsi te c) Esi te d)Fsi te
15.
BeadleandTat um concludedt hatgenespr oducet heireffectsbyspeci f
yingthestructureof:
a)Aminoaci ds b)Vi tami ns c) Fer ment ers d)Enz ymes
16.
BeadleandTat um exposedNeur ospor aspor esat :
a)X-r
ay s b)Gammar ay s c) Al pha- r
ay s d)Bet a-r
ays
17.
Eachenzy meinar gini
nebi osynt heticpat hwaywasst udiedby :
a)Watson&cr i
ck b)Beadl e&Tat um c) Har shey & d)Dar win
chase &fr
anci s
18.
Chr
omosomal t
heor
yofinher
it
ancewasfor
mul
atedby
:
a)Wal
therf
lemi
ng b)T. H.Mor
gan c) Walt
er d)Johnbr
own
Sut
ton
19.
Chr
omosomesar ecomposedof:
a)RNA&protei
n b)DNA&sugar s c) DNA&Fat
s d)DNA&
Pr
otei
ns
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20.
Chr
omosomessegr
egatesduri
ng:
a)Amit
osis b)Mi t
osis c) Mei
osi
s d)None
21.
Chr
omosomeswerefi
rstobservedi
n1882by
:
a)Wal
therfl
emi
ng b)T.H.Morgan c) Walt
er Johnbr
own
sut
ton
22.
Copy i
ngofmRNAf
rom DNAi
scall
ed:
a)Translat
ion b)Tr
anscri
pti
on c) Transducti
o d)Tr ansf
ormati
n on
23.DNAchangesar ecalledmut at
ionsandtheor
gani
sm thatundergonesuchchangesare
call
ed:
a)Wildtypes b)Changer d)Mut ants e) Transmutant
s
24.Arelati
vel
ysmallenzymet hatplay
sasupport
ingr
olei
nDNAr epl
icat
ioni
s:
a)DNApol ymer
ase-I b)DNApol y
merase- c) DNA d)DNA
II polymerase- polymerase-
II
I I
V
25.AroleinDNArepairisplay
edby :
a)DNA e) DNApol
ymer
ase- f) DNA g)DNA
pol
ymerase-
I I
I poly mer ase- pol ymer ase-
II
I I
V
26.
Nucl eoti
desar eonl yaddedt othe3’ endofaDNAst r
andby :
a)DNAPol ymer ase- I b)DNAPol ymer ase- c) DNA d)DNA
II Poly mer ase- Pol ymer ase-
II
I I
V
27.
EachOkazakif ragment sissynthesizedby :
a)DNAPol ymer ase- I b)DNApol ymer ase- c) DNA d)DNA
II Poly mer ase- pol ymer ase-
II
I I
V
28.
Eacht RNAhasasequenceoft hreebasi s,call
edant i
codon, whi chiscompl ement ar yt o
codonof :
a)rRNA b)tRNA c) mRNA d)nRNA
29.
enzy me, primase, construct
sanRNApr imer,asequenceofabout10RNAnucl eot i
des
compl ement ar yt oDNA:
a)pat t
ern b)cut-cut c) stenci l d)t empl ate
30.
whoshowedt hatamountofadeni neinDNAi salway sequal st heamountt hymi ne, andt he
amountofguani nei salwaysequal stheamountofcy t
osine:
a)Erwinchar gaff b)JamesWat son c) Mar tha d)Wal ter
chase Sut ton
31.
Ev er
y200nucl eot ides,theDNAdupl exiscoi l
edar oundacor eofei ghthi
stonepr ot eins
formi ngacompl exknownasa:
a)Histomone b)Nucl eosome c) Per oxi some d)Gl yoxisome
32.
Ev er
ygenest artswi thcodonAUG, whichnor mallyencodest heami noacids:
a)Arginine b)Citrull
i
ne c) Met hi oni ne d)Ly sine
33.
DNAwasdi scov eredin1869by :
a)Erwinchar gaff b)AlfredHar shey c) Wal ter d)Fr iedr i
ch
Flemi ng Mi escher
34.
Genet iccodei sacombi nati
onof3nucl eotidesinDNAwhi chspeci fyaparticul
ar:
a)Ami noaci ds b)Fattyacids c) Vitami ns d)St eroids
32 35
35. Pand Sl abel edv ir
useswer eusedi nexper i
ment sby:
a)Wat son&cr ick b)Har shey&chase c) Wi l
ki ns& d)Cor rens&
Frankl i
n bridge
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36.
Highl
ycondensedpor
ti
onofchr
omati
niscal
l
ed:
a)Homochromatin b)Euchromat
in c) Het erochr o d)Achr omat in
mat in
37.
Hist onesar eposi t
ivelychar gedduet oabundanceoft hebasi cami noaci ds:
a)Argi nine b)Ly sine c) Bot ha&b d)Al ani ne
38.
Humancel lcont ai
nabout45di ffer entki ndsof :
a)tRNA b)r RNA c) mRNA d)cRNA
39.
Humancel l
shav e46chr omosomes, consist ingof ………. pairs:
a)20 b)21 c) 22 d)23
40.
Ifaeukar yot i
cDNAi sexami nedwi thanel ect ronmi croscope, itresembl esast ringof :
a)Blobs b)Beads c) Gl obul es d)Vesi cles
41.
Ifthest randofDNAf rom asi ngl echr omosomeswer el aidouti nast r
aightl i
ne, itslengt h
woul dbeabout ……….Cm:
a)2 b)15 c) 5 d)20
42.
In1910ThomasHuntMor gan, study i
ngt hef rui tfl
y ,
dr osophi lamel anogast er,det ecteda
mut ant :
a)Whi teey edmal e b)Whi teey edf emal e c) Redey ed d)Redey ed
fly fly mal ef ly femal ef l
y
43.
In1944, Oswal dAv eryal ongwi thCol i
nMacl eodandMacl y nMcCar tyrepeat ed
exper iment sof :
a)Lamar ck b)Gr i
ff th c) Dar win d)Spemann
44.
In1952byAl fr
edHar sheyandMar thaChaseexper i
ment edwi thbact eriophages:
a)T1 b)T2 c) T3 d)T4
45.
In1953Wat son&Cr i
ckpr oposedst ructur eoft he:
a)RNAmol ecul e b)ATPmol ecule c) DNA d)NAD
mol ecul e mol ecul e
46.
In1953, Fr edrickSanger , descr ibedt hecompl etesequenceofami noaci dsof :
a)My ogl obi n b)Ker at i
n c) Gl obul in d)I nsul in
47.
Inal kapt onur iathepat ientpr oducedur i
net hatcont ained:
a)Homogenet i
sic b)Absci sicaci d c) St ear i
caci d d)Adeny lic
acid acid
48.
Inbact eriat henewl ysy nthesi zedmRNAi sdi r ectl
yr eleasedi nto:
a)Prot opl asm b)Cy topl asm c) Nucl eopl as d)None
m
49.
Ineukar yotest hebi ndingsi tesofpr omot erar eat:
a)-20&- 70 b)- 20&- 50 c) - 25&- 70 d)- 35&- 80
50.
Inpheny lketonur i
a,pheny lalaninei snotdegr adedbecauseofdef ect i
veenzy me
pheny lalanine:
a)Cat alase b)Oxi dase c) Reduct ase d)Hy droxy l
ase
51.
Inpr okar yotewi thinpromot ert her ear etwobi ndingsi tesTTGACAal socal led- 35
sequenceandTATAATal socal l
ed………….Sequence:
a)-10 b)- 20 c) - 30 d)- 35`
52.
Inpr okar y otest r
anslationbegi nswhent hei nit i
alpor t
ionofmRNAmol eculebi ndst o:
a)tRNA b)r RNA c) ami noaci ds d)pept idechi n
53.
insi cklecel lanemi aapoi ntmut ationl eadst ochangeofami noaci dgl utami caci di nt o:
a)arginine b)l ysine c) v aline d)al anine
54.
insi cklecel ldisease, asi nglet hy mi nei srepl acedwi thanadeni nei ntheDNAt hatcodes
for:
a)vali
ne b)hi st i
dine c) gl ycine d)gl utami c
acid
55.
inthedoubl ehel i
xofDNAadeni nef or mt wohy drogenbondswi th:
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a)t hymi ne b)guani ne c) cy tosi ne d)ur acil

56.i
nt hedoubl ehel i
xofDNAguani nef or mst hreehy drogenbondswi th:
a)t hymi ne b)guani ne c) cy tosi ne d)ur acil
57.Leadi ngst r
andi sbui ltupsi mpl ybyaddi ngnucl eotidescont i
nuousl yt oit
sgr owing……. .
end:
a)5’ b)3’ c) Bot ha&b d)None
58.Lev eneconcl udedt hatDNA&RNAmol eculesar emadeofr epeat i
nguni t
sof:
a)Nucl eot ides b)Nucl eosomes c) Nucl eic d)Nucl eosides
acids
59.Allthe64codonswer et est ed:
a)Mar shal l b)Phi li
pLeader c) Har Gobi ndkh d)Al l
Nirenber g orana
60.Miescherext ractedawhi tesubst ancef rom thenucl ei ofhumancel lsandf ishsperm, he
calledt hi ssubst ance:
a)Nucl ein b)Nucl eicaci d c) Nucl eoi d d)Nucl eotide
61.Mostchr omosomesar eabout :
a)20%DNA&80% b)40%DNA&60% c) 30%DNA& d) 50%DNA
Prot ei
ns pr oteins 70%pr oteins &50%pr otei
ns
62.Mut ationscanbr oadl ybecl assi fiedas:( 1)chr omosomalaber rationand( 2):
a)Di rectmut ation b)Dotmut ation c) Poi nt d)Si t
e
mut at i
on mut ati
on
63.Okazaki fragment sar eabout100- 200nucl eot i
desl ongi n:
a)Pr okar y otes b)Eukar yot es c) Bot ha&b d)None
64.Okazaki fragment sar eabout1000- 2000nucl eotidesl ongi n:
a)Pr okar y otes b)Eukar yot es c) Bot ha&b d)None
65.Oncet het ranscr iptionhasst artedt hesi gmaf actori sr el
easedandcor eenzy memov es
overt he:
a)Templ atest rand b)Ant i-sensest rand c) Codi ng d)Bot ha&b
strand
66.Onlyoneoft het wost randsofDNAar etranscr i
bed, thisst r
andi scal led:
a)Templ atest rand b)Ant i-sensest rand c) Sensest rand d)Bot ha&b
67.Originsi teofr eplicationi sonei n:
a)Pr okar y otes b)Eukar yot es c) None d)Bot ha&b
68.Ther ear esev eralor i
gi nsitesofr eplicat i
onin:
a)Pr okar y otes b)Eukar yot es c) None d)Bot ha&b
69.Whof oundt hatDNAcont ainst hr eemai ncomponent s:
a)Lev i
ne b)Lev er c) P. A.Lev ene d)Lor enz
70.Pointmut ati
onsar emut at i
onalchangeswhi chaf fectt hemessagei tsel
f,producing
alt
er ationi nsequenceof :
e) DNA f) RNA g)Ami noaci ds h)ATP
71.Poly mer ase- IIIprogr essi velyt hreadst heDNAt hrought heenzy mecompl exmov i
ngi tat
rapidr at eofsome……………nucl eot ide/ second:
a)4000 b)2000 c) 500 d)1000
72.Af ungust hathasonepai rofchr omosomesi s:
a)Asper gi l
lus b)Penci ll
ium c) Mucor d)Rhi zopus
73.Prot ei
nscal ledel ongat i
onf act orsassi stinbi ndingt RNAt ot heexposedmRNAcodonat :
a)Psi te b)Esi te c) Asi te d)Dsi t
e
74.Prot ei
nscal l
edi nitiationf act orposi tionthet RNAonr i
bosomal surf aceatt he:
a)Psi te b)Esi te c) Asi te d)Dsi t
e
75.Thedi rect ionofr eplicat i
oni sal way s:
a)3’ to5’ b)5’ to3’ c) Bot ha&b d)None
76.RNApol y mer ase- Isy nthesi zes:
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a)rRNA b)mRNA c) t RNA d)pr otein

77.
RNApol y mer ase- I
Isy nthesi zes:
a)rRNA b)mRNA c) t RNA d)pr otein
78.
RNApol y mer ase- I
IIsy nthesi zes:
a)rRNA b)mRNA c) t RNA d)pr otein
79.
RosalindFr anklincar ri
edanX- raydi ffractionanal ysi
sof :
a)RNA b)ATP c) NAD d)DNA
80.
Sickl
ecel lanaemi aandpheny leket onur iaar ev erywel lknownexampl esof:
a)Pointmut ation b)Chr omosomal c) Si te d)Dotmut ation
aber rat i
on mut ati
on
81.
Thef act orr esponsi blef orcor rectr ecogni t
ionofbi ndingsi teandi ni
ti
ati
onoftranscription
processi s:
a)Alphaf act or b)Si gmaf act or c) Bet af actor d)Pi factor
82.
Somechr omosomal aber rationi nv olves:
a)Presenceofan b)Lossof c) Bot ha&b d)None
extra chr omosome
chromosome
83.
Thenumberofchr omosomesi nf ernsi smor et han……pai rs:
a)200 b)300 c) 400 d)500
84.
Synthesi sofpr oteiniscal led:
a)Translation b)Tr anscr ipt i
on c) Tr ansduct io d)Tr ansformat i
n on
85.
Theact iv atingenzy me, ami noacy l
et RNAsy nt hetase, catalyzest heat t
achmentofami no
acidst ospeci fi
c:
a)rRNA b)t RNA c) mRNA d)cRNA
86.
theamountofi nfor mat iononechr omosomecont ainswoul dfillabout:
a)80pr i
ntedbooks b)200pr i
nt edbooks c) 280pr inted d)380pr inted
of100pageseach of1000pages booksof booksof
each 1000pages 1000pages
each each
87.
Thebi ndi ngofRNApol ymer aset opr omot eri sfirststepi ngene:
a)Translation b)Tr anscr ipt i
on c) Tr ansduct io d)Tr ansformat i
n on
88.
ThecapofmRNAi sint hef or m of :
a)ATP b)CTP c) UTP d)GTP
89.
Thecapsandt ail
ssav et hemRNAf rom v arietyof:
a)Nucleases b)Phosphat ases c) Bot ha&b d)Reduct ases
90.
Thechr omosomesacqui r
edi f
fer entshapesatt het i
meof :
a)Anaphase b)Met aphase c) Pr ophase d)Tel ophase
91.
Thechr omosomesar ecal ledt el ocent r
ic,acr ocent r
ic,sub- met acentri
c&met acentric
dependi ngupont helocat ionof :
a)Blastomer e b)Mi cromer e c) Cent r
omer e d)Ki netomer e
92.
Thecodef orspeci f
yingami noaci dsdoesnotconsi stof3- bases.Thi siscal
ledthe:
a)Doubl etcode b)Tr ipletcode c) Quadr uplet d)None
code
93.
TheDNAmol ecul ehadashapeofahel ixwi thdi amet erof2nm andcompl etehelicaltur n
every:
a)0.4nm b)1. 4nm c) 2. 4nm d)3. 4nm
94.
TheDNAmol ecul eissi mpl e:
a)Doubl ehel ix b)Tr iplehel ix c) Doubl ecur l d)Doubl etwi rl
95.
TheDNAr eplicati
onbegi nsatoneormor euni quesites, call
edt heor i
ginofrepl
i
cationand
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pr
oceeds:
a)Uni
dir
ecti
onal
l
y b)Bi
dir
ect
ional
l
y c) Mul tidirectio d)None
nal l
y
96.Thef i
rstev idenceofher editynat ur eofDNAwaspr ov idedby :
a)Fr edr i
ckMi scher b)Wal t
herFl emi ng c) Fr edr i
ck d)Wal ter
Gr i
ffith Sut ton
97.Thegenecausi ngt hewhi teey et raitindr osophi lar esi desonl yont he:
a)Aut osome3 b)Aut osome7 c) Y d)X
chr omosom chr omosom
e e
98.Thegenet i
ccodei s:
a)Uni versal b)Non- uni ver sal c) Wor ld-wi de d)Common
99.Thel aggi ngst r
andofDNAi ssy nthesi zedcont i
nuousl yasaser iesofshor t
………segment s:
a)Hanuka b)Okazaki c) Rock d)Gol dberg
100. Thel inkagei scalledphosphodi est erbondbecauseofphosphat egroupislinkedt o
thet wosugar sbymeansofapai rof:
a)Pept idebond b)Gl y cosidi cbond c) Est erbond d)Hy drogen
bond
101. TheMesel son-Stahlexper i
mentconf i
rmedt hepr edi ctionoft heWatson-Cr i
ck
modelt hatDNAr eplicationi s:
a)Semi -
conser vative b)Conser vat ive c) Di sper sive d)Semi -
disper si
v e
102. Thenon- sensecodonsar eusual l
ypr esentatt heendoft hegeneandhencet heyar e
alsocal led:
a)St artcodons b)St opcodons c) Ter mi nal d)Lat ecodons
codons
103. Thepar t
icularar rayofchr omosomest hatani ndividualpossessesi scal
led:
a)Ki net ochor e b)Ki net omer e c) Kar yot ype d)Kar yon
104. Thepor tionofchr omat inot hert hanhet erochr omat i
ni scal l
ed:
a)Homochr omat in b)Euchr omat in c) Achr omat i
n d)None
105. Ther iboseof7- met hy l
eguanosi neandt hef irstnucl eot ideofmRNAar elinkedby5’
to5’ :
a)Bi -phosphat e b)Tr i
-sulphat e c) Tr i
-nitrate d)Tr i-
bridge bridge bridge phosphat e
bridge
106. TheRNApol ymer aseenzy messy nthesizeRNAf r
om:
a)5’ -3’direction b)3’ -5’di r
ect ion c) 1’ -3’ d)5’ -
2’
direct i
on direction
107. Thesequenceofnucl eot i
dest hatdet ermi nest heami noaci dssequenceofapr otein
i
scal l
eda:
a)Al lele b)Gene c) Jean d)Codon
108. Intranscr i
ption,thesi mpl estst opsi gnalisaser iesof :
a)GCbasepai rs b)ATbasepai r
s c) ACbase d)GTbase
pai r
s pairs
109. Thest randopposi tetot empl at est r
andi scal led:
a)Codi ngst rand b)Sensest rand c) Ant i-sense d)Bot ha&b
strand
110. Thet ailofmRNAi sint hef orm ofPol y
-Alinkedt o3’ endoft he:
a)r RNA b)mRNA c) t RNA d)cRNA
111. thet ransf erofi nformat i
onf rom RNAt opr otei nsi scal led: t
ranscri
pti
on
a)t ranscr i
ption b)t ransduct ion c) t ransl ation d)t r
ansf ormati
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on
112. thetrueE.Col ir
epli
catingenzy mesi sDNApol ymerase:
a)I b)I I c) II
I d)I v
113. Therear et hreeDNApol y
mer asesnamel yI,I
IandIIIin:
a)Vi rus b)Yeast c) Fungi d)Bact eria
114. Therei sonl yonet y
peofRNApol y mer asei n:
a)Pr okar yotes b)Eukar yotes c) Bot ha&b d)None
115. ThreecodonsUAA, UAG&UGAdonotcodef oranyami noaci ds&hencear eknown
as:
a)Non- sensecodon b)St opcodon c) Sensecodon d)Bot ha&B
116. Thymi ne, cy t
osineandur acilar ecal l
ed:
a)Pur ines b)Py rimidines c) Urinates d)None
117. Transcr i
pt ionisinti
atedwhent heenzy meRNApol y mer asebi ndstoapar ticular
bindi ngsi tecal leda:
a)Demot er b)Tr ot ter c) Promot er d)Si gmaf actor
118. Transcr i
pt i
oni stheprocessi nwhi chanRNAcopyoft heDNAsequenceencodi ng
thegenei spr oducedwi t
hhelpof :
a)RNApol ymer ase b)DNApol ymer ase c) RNAl i
gase d)RNA
Isomer ase
119. Transcr i
pt ionstartsatt heRNApol y
mer asebindingsi tecal l
edpr omoteronDNA:
a)Templ at estrand b)Ant i-
sensest r and c) Bot ha&b d)Codi ng
strand
120. Transf ormat ionisthet ransferofgenet icmat eri
alfr
om onecel ltoanot
herandcan
altert hegenet icmakeupoft he:
a)Donorcel l b)Reci pientcel l c) Bot ha&b d)None
121. Typical l
yachr omosomei smadeof :
a)Chr omat ids b)Cent romer e c) Secondar y d)Al l
const riction
122. UGAcodoni snor mallyast opcodonbuti nmi tochondr iai treadsas:
a)Val i
ne b)Tr y ptophan c) Glumat ic d)Pheny l
al ani
n
acid e
123. Vernoni ngr am in1956di scov er edmol ecularbasisofsi ckl ecel l
anemia,apr otei n
def ecti nheritedas:
a)Mendel i
an b)Monogol ism c) AZ d)Non-
disor der syndr ome disjunct ion
124. Ther apidf ragment soft hel aggi ngst randar eat t
achedbyenzy me”
a)DNApol ymer ase b)RNAl i
gase c) DNAl igase d)RNA
topoi somer a
se
125. Whichoft hef ol
lowingi snonsensecodon:
a)AUG b)AAA c) UAA d)UUC