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3rd Week of Dev

EMBRYOLOGY

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12 views

3rd Week of Dev

EMBRYOLOGY

Uploaded by

dejilo9839
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Previous Class

After 2nd Week We Found-

Bilaminar germ disc


Amniotic cavity
Secondary yolk sac
Chorionic cavity
Cytotrophoblast
Syncytiotrophoblast

1
Dr.Mostafa
THIRD WEEK OF DEVELOPMENT
(Trilaminar Germ Disc)

GASTRULATION

Presented by-
Dr. AHM Mostafa kamal
www.ahmmostafakamal.com

Dr.Mostafa 2
Third Week of Development
(Trilaminar Germ Disc)

GASTRULATION
The process of formation of trilaminar germ disc is
called gastrulation.
(ectoderm, mesoderm & endoderm)

Gastrulating begins with formation of the primitive


streak on the surface of the epiblast

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PRIMITIVE GROOVE – Caudal to cranially a groove
appears on the surface of epiblast is called primitive groove.

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PRIMITIVE STREAK – Epiblastic cells are elevated on
each side of the groove, it extend up to primitive node.

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PRIMITIVE NODE – Collection of epiblastic cell at
the end of the primitive streak.

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PRIMITIVE PITS – Collection of epiblastic
cell at the end of the primitive streak

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Gastrulation : Formation of all the three germ layers

Cells from primary streak migrate then invaginate


between epiblast and hypoblast and this inward
movement is known as invagination

Some epiblast cell displace the hypoblast and form


endoderm

Other come to lie between epiblast and newly created


endoderm to form mesoderm

Remaining epiblast cells from ectoderm


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Epiblast is the source of all 3 germ layer

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Sacro - Coccygeal Teratoma

If epiblastic cells are persist caudally in the


primitive streak it can form teratoma

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Formation Of Notocord

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Formation of Notocord (Contd…)
Most cranially epiblast and hypoblast adherent called
prechordal plate, which rupture to form
buccopharyngeal membrane.
Most caudally epiblast and hypoblast adherent called
cloaca, which rupture to form anus.

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Prechordal plate & Cloaca

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Formation of Notocord (Contd…)
 Notochordal process is formed by epiblastic cell
 Extend from the primitive node to the buccopharyngeal
membrane
 A neurenteric canal is formed within notochordal process
which connect amniotic cavity to yolk sac.

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Formation of Notocord (Contd…)
Cells of notochordal
process intermingle with
endodermal cell.

Latter they separate


from endoderm.

Cells will proliferate


and become solid cord,
the definitive notochord.

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gg

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Ramnent of Notochord

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Mesoderm (Fate Map)

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Mesoderm (Fate Map)
Cells that migrate from the primitive node and from
cranial end of the streak become Paraxial
mesoderm

Cells migrating through the midstreak region become


intermediate mesoderm

Those migrating through the caudal part of streak


become lateral plate mesoderm

Caudalmost part of the streak contribute to


extraembryonic
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mesoderm 19
Mesoderm

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Development of the Trophoblast
Primary villi: consists of
• Cytotrophoblast
• Syncytiotrophoblast

Secondary villi: consists of


• Cytotrophoblast
• Syncytiotrophoblast
• A central core of primary
mesoderm
Tertiary villi: Consists of
• Cytotrophoblast
• Syncytotrophoblast
• Primary mesoderm
differentiate into blood
vessels Dr.Mostafa 21
Third Week of Development
SUMMARY
Gastrulation
Primitive streak
Primitive node
Notochord
Buccopharyngeal membrane
Cloaca
Primary, secondary and tertiary villus

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THANK YOU ALL

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