PRINCIPLES OF INHERITANCE AND VARIATION – Assignment 3

46. In a Mendelian dihybrid cross if the individuals with all the four kinds of alleles are 30 in F2
generation, find out the total number of F2 individuals
1) 120 2) 300 3) 240 4) 1600
47. In a Mendelian dihybrid cross the number of phenotypic recombinants is 36 in F2 generation. The
number of organisms with the genotype that itself accounts for 1/4th of F2 generation is
1) 48 2) 24 3) 18 4) 12
48. When a heterozygous maize plant with colored and full endosperm seeds is crossed to a plant with
colorless and shrunken seeds, in the progeny 480 colored full endosperm seed containing, 480
colourless shrunken seed containing 20 colored shrunken seed containing and 20 colorless and full
endosperm seed containing plants are produced. What is the percentage of recombination?
1) 96 2) 4 3) 50 4) 2
49. Which of the following is suitable for experiment on linkage?
1) aaBB × aaBB 2) AaBb × aabb
3) AaBb × AaBb 4) AAbb × AaBB
50. Study the following lists
List-I List-II
(Genotypes) (Probability in F2 progeny)
A) YYrr I) 4/16
B) YyRr II) 1/16
C) yyrr III) 2/16
D) yyRr IV) 1/16
V) 2/16
The correct match is
A B C D A B C D
1) III V I II 2) IV I II III
3) III V IV I 4) I V III IV

51. A human showing two Barr bodies in the somatic cells would be
(a) only a male with one X - chromosome
(b) only a female with two X chromosomes
(c) only a male having two Y - choromosomes
(d) either a male or a female having three X – choromosomes
52. Ram has hairy ears (hypertrichosos), a trait carried by a gene in his Y - chromosome. What
is the chance that his grandson will inherit the trait from him?
(a) 0% (b) 25% (c) 50% (d) 100%
53. A colourblind mother and normal father would have
(a) colourblind sons and normal/carrier daughters
(b) colourblind sons and daughters
(c) all colourblind (d) all normal
54. A man with certain disease marries a normal woman. They have eight children (three
daughters and five sons). All the daughters suffer from their father's disease, but none of
the sons are affected. Which of the following mode of inheritance do you suggest for this
disease?
(a) Sex - limited recessive (b) Autosomal dominant
(c) Sex - linked dominant (d) Sex - linked recessive
55. When both parents are of blood type AB, they can have children with
(a) A, B, AB and O blood types (b) A, B and AB blood type
(c) A and B blood types (d) A, B and O blood types
56. A colourblind man marries the normal daughter of a colourblind man. In their progeny
(a) all their sons will be colourblind (b) half of their sons will be colourblind
(c) none of their daughters will be colourblind (d) all their daughters will be colourblind
57. Erythroblastosis foetalis occurs
(a) When the mother is Rh negative and the child is Rh positive
(b) When the father and child are both negative, but the mother is positive
(c) When the mother and child are both Rh positive, but the father is Rh negative
(d) When the mother and father are Rh positive, but the child is Rh negative
58. In human, red-green colour blindness is recessive and sex-linked, while albinism is
recessive and autosomal. A marriage between two homozygous parents, a normal visioned
albino woman and a colourblind and normally pigmented man will produce children
(a) Who are all phenotypically normal visioned and have normal pigmentation
(b) half of whom are colourblind and other half having normal vision and all of them having
normal pigmentation
(c) all of whom have normal vision, but half of whom are albino and the other half with
normal pigmentation
(d) of four categories normal visioned pigmented; normal visioned albino; colourblind,
pigmented; colourblind, albino; all in equal proportions
59. A holandric gene is known for hypertrichosis (long hair on ears). When a man with hairy
ears marries a normal woman, what percentage of their daughters would be expected to
have hairy ears?
(a) 0% (b) 100% (c) 50% (d) 2.5%
60. One way to determine sex - linked inheritance is
(a) son resembles mother and daughter resembles father
(b) both son and daughter resemble mother
(c) both son and daughter resemble mother
(d) son resembles father and daughter resembles mother
61. Father has blood group-A and mother's blood is B. Both are heterozygous. If they have
identical twins, the percentage probability of both twins having blood group A is
(a) 100% (b) 50% (c) 25% (d) 6.25%
62. Child has blood group 'O' and his father is 'B' type. Then genotype of the father should be
(a) I0 I0 (b) IB I0 (c) IA IB (d) IB IB
63. Usually, the recessive character is expressed only when present in a double recessive
condition. However, single recessive gene can express itself in human beings when the
gene is present on
(a) the X-chromosome of the female (b) the X-chromosome of the male
(c) any autosome (d) either an autosome of X-chromosome
64. A woman has a child with Klinfelter's syndrome. The number of Barr bodies present in her
child is
(a) one (b) two (c) three (d) None of these
65. One normal couple, half of sons are haemophilic and half the daughters are heterozygous.
The genes for this disease in couple are located on
(a) both X-chromosomes of mother (b) Y-chromosomes of father
(c) one X-chromosomes of mother and X-chromosomes of father
(d) both sex - chromosomes of the father
66. A colourblind daughter will be born when the mother is
(a) colourblind and the father is carrier but not colourblind
(b) carrier and the father is colourblind
(c) normal and non-carrier but the father is colourblind
(d) mother and father are both carriers but none of them is colourblind
67. A colourblind girl is rare and can be born when
(a) her father is colourblind and mother has normal vision but her mother's father
(maternal grandfather) is colourblind
(b) her mother is colourblind, even if father has normal vision
 (c) even when both her parents have normal vision provided the grandparents were
colourblind
(d) her mother is colourblind and her father had normal vision but her paternal
grandfather (father's father was colourblind)
68. In man, the mechanism of sex-linked inheritance is generally from
(a) father to daughter to grandson (b) father to daughter
(c) daughter to grandson (d) father to son to grandson
69. The gene for haemophilia is located on the chromosome of humans. It is normally
impossible for a
(a) haemophilic father to pass the gene to his son
(b) carrier mother to pass the gene to her son
(c) haemophilic father to pass the gene to his daughter
(d) carrier mother to pass the gene to her daughter
70. Sita and Ram have their first child. Sita know her blood type is A, but ram does not know
his blood type. However, Ram knows that both his mother and father have type B blood.
The first child is a boy named kush. kush has type O blood. Sita and Ram do not understand
how this happened. Which of the following is the best explanation
(a) Sita's genotype is AA and Ram's genotype is OO; thus, skip expressess the O phenotype
(b) Sita's genotype is AO and Ram's genotype is OO; thus, skip expressess the O phenotype
(c) Because Ram's parents are both type B, Ram is not Khush's father
(d) Khush's blood type will need to be checked after his first month of life, if Sita and Ram
want to know his blood type, as it takes about a month for the blood type to develop in a
newborn child
71. A woman with cystic fibrosis, an autosomal recondition, marries her first cousin. What is
the risk that their first child will have cystic fibrosis?
(a) 1/4 (b) 1/2 (c) 3/4 (d) 1/8
72. A man affected with brachydactyly, an autosomal dominant trait that causes shortening of
several fingers. What is the risk that man's first child will have brachydactyly?
(a) 25% (b) 50% (c) 75% (d) 100%
73. A man and woman who both have Bb genotypes at a locus will produce what proportion
of Bb children?
(a) 25% (b) 50% (c) 75% (d) 100%
74. How can a female be colourblind?
(a) Both parents normal (b) Father normal, mother carrier
(c) Father colourblind, Mother carrier (d) Father colourblind, mother normal
75. Mr Phillips is colourblind. What is the probability of his male child inheriting this disease
from him?
(a) 100% (b) 25% (c) 50% (d) 0%