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series application questions

Series Application Questions

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series application questions

Series Application Questions

Uploaded by

muhammad.hannan24621
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 2

Salim Habib University

Department of Biomedical Engineering


Assignment

Electrical Activity in Neurons

The propagation of electrical signals along a neuron is governed by the cable equation:

𝜕 2𝑉 1 𝜕𝑉
2
− =0
𝜕𝑥 𝑅𝑚 𝐶𝑚 𝜕𝑡

Where

V(x,t) is the voltage along the length of the neuron

membrane resistance is 𝑅𝑚 = 1𝑀𝛺

membrane capacitance is 𝐶𝑚 = 1𝜇𝐹/𝑐𝑚2

Question:

a) Use a power series expansion to solve for 𝑉(𝑥, 𝑡) around 𝑥 = 0, assuming the initial condition
𝑉(0, 𝑡) = 𝑉0

b) Explain how this solution helps predict the voltage changes along a neuron over time, and
how it can be used to better understand signal transmission in neurons for medical devices like
neurostimulators.

Page 1 of 2
Thermal Ablation in Cancer Treatment:

Thermal ablation is a technique used to destroy cancerous tissues by heating them. The
temperature distribution in tissue during thermal ablation is governed by the heat conduction
equation:

𝜕𝑇 𝜕2𝑇
=𝑘 2 +𝑄
𝜕𝑡 𝜕𝑟

where 𝑇(𝑟, 𝑡)is the temperature at a distance 𝑟 from the heat source, 𝑘 is the thermal diffusivity,
and 𝑄 is the heat source term.

𝑐𝑚2
where: 𝑘 = 0.001 , 𝑄 = 10𝑊/𝑐𝑚3
𝑠

Question:
a) Use a series solution to find the temperature distribution 𝑇(𝑟, 𝑡) near 𝑟 = 0, assuming an initial
temperature 𝑇(𝑟, 0) = 𝑇0
b) Discuss how this solution can be used to optimize the energy delivery during thermal ablation
procedures and minimize damage to surrounding healthy tissue.

Page 2 of 2

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