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NILESH

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13 views

NILESH

Uploaded by

choudhary25092000
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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lOMoAR cP SD| 31 72 0 42 4

A PROJECT REPORT ON
Development of TLC Using Silica Gel

For partial fulfillment of B.pharma 7 th semester

Session: 2024-25
Dr. A.P.J. Abdul Kalam Technical
University Lucknow

Institute of Pharmacy
HCPG College
Bawan Bigha , Varanasi, 221002

SUBMITTED BY :- Supervision
NILESH MAURYA
B.pharma 4th Year Mrs. Ankita Yadav
Roll no. 2102050500059
( ASSISTANT PROFESSOR )
lOM oARcP SD| 31 72 042 4

CERTIFICATE
This certify that NILESH MAURYA Student of the Institute of Pharmacy HarishChandra P.G.
College, Varanasi has undertaken this project Development of TLC Using Silica Gel.
The project has been carried out by the student fulfillment of the requirement under our
my supervision & guidance.

DIRECTOR OF INSTITUTION: -

Director
Dr. Manish Kumar Gupta
Institute of Pharmacy, Harish Chandra P.G. College,
Varanasi-221002
lOMoAR cPSD| 31720424

DECLARATION

I hereby declare that the project entitled “Development of TLC using silica Gel”is
as my own effort the guidance of Mrs. Ankita Yadav, Assistant Professor. This project is
submitted to the Institute of Pharmacy Harish Chandra P.G. College, Varanasi for the
partial fulfilment of the “BACHELOR OF PHARMACY”.
lOMoAR cPSD| 31720424

ACKNOWLEGEMENT

I would like to express my regards and deep sense of gratitude towards our mentor Mrs. Ankita
Yadav, Assistant Professor who gave us the golden opportunity to work on the project entitled
“Development of TLC using silica Gel” and provide continuous support and guidance that
made this project completed successfully.

Thanking you NILESH MAURYA


B.pharma 4 th Year
Roll no. 2102050500059
lOMoAR cPSD| 31720424

ABSTRACT

In the present article attempt has been made to explain the basic ideas and the significance of
Thin layer Chromatography (TLC) in different analytical methods. As TLC is less time consuming,
low cost, and can be performed with less complicated technique it has a wide application in
pharmaceutical analysis. If performed precisely 32 amino acids can be separated by TLC. Also it
has a wide application in identifying impurities in a compound. It can be used as a preliminary
analytical method prior to HPLC. The concept of TLC is simple and samples usually require only
minimal pretreatment. TLC can be used to monitor the progress of a reaction, identify compounds
present in a given substance. TLC is also used to separate the identical compounds in a mixture.
Many standard methods in industrial chemistry, environmental toxicology, food chemistry, water,
inorganic and pesticide analysis, dye purity, cosmetics, plant materials, and herbal analysis rely
upon TLC as the preferred approach.

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